Polytene chromosomes normal.
macrochaeta & head
macrochaeta & scutum
H2 heterozygous adults also expressing Rbfox1dsRNA.Scer\UAS under the control of Scer\GAL4sca-109-68 exhibit an enhanced loss of thoracic sensory bristles and exhibit a significant amount of sockets instead of bristles, as compared to H2 heterozygotes.
A Eps-152/Eps-15EP2513 transheterozygous background significantly enhances the hair loss phenotype observed in H2 heterozygotes. This enhancement is gene dosage dependent with loss of both copies of Eps-15 increasing the hair loss to 46%, accompanied by increases of nearly four-fold in the number of double sockets and nearly two-fold in the number of areas with no external sensory organs.
Effects on wing development by dx24/Y and H2/+ are mutually levelled. dx24/Y wing phenotypes, both regarding vein broadening and spread out wings, as well as haploinsufficient vein shortening in H2 mutants are largely restored in dx24/Y, H2/+ flies. Yet the fragile wing texture typical of dx mutants remains.