Open Close
General Information
Symbol
Dmel\TrpA1UAS.cUa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Unknown
FlyBase ID
FBal0291243
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-dTrpA1, UAS-TrpA1, UAS-DmTRPA1
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of TrpA1.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Activation of Tdc-positive neurons by expressing TrpA1Scer\UAS.cUa under the control of Scer\GAL4Tdc2.PC in virgin females at the permissive temperature induces post-mating behaviors. These include reduced levels of copulation within one hour, increased rejection behaviors (ovipositor extrusion) and increased egg laying.

Single vdaB class IV dendritic arborization neuron cells expressing TrpA1Scer\UAS.cUa under the control of Scer\GAL4ppk.PU at 30[o]C show a dorsal shift in the position of their presynaptic terminals compared to controls. The topography of the presynaptic terminals of v'ada class IV da neurons is unaffected if they express TrpA1Scer\UAS.cUa under the control of Scer\GAL4ppk.PU as single cell clones at 30[o]C.

Expression of TrpA1Scer\UAS.cUa under the control of Scer\GAL4GMR.PF at 29[o]C eliminates the difference in LN(v) dendrite length that is normally seen in constant darkness versus constant light conditions in wild-type larvae.

Overexpression of TrpA1Scer\UAS.cUa in class I dendritic arborization neurons (under the control of Scer\GAL421-7) confers allyl isothiocyanate sensitivity but not a response to light on these neurons.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
NOT suppressed by
Statement
Reference

Scer\GAL4NPF.1, TrpA1UAS.cUa has abnormal sleep | heat sensitive phenotype, non-suppressible by NPFUAS.cWa, Scer\GAL4NPF.1

Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of TrpA1Scer\UAS.cUa under the control of Scer\GAL4TrpA1.PU rescues the increased temperature preference seen in TrpA11 mutant flies.

Expression of TrpA1Scer\UAS.cUa under the control of Scer\GAL4ppk.1.9 rescues the delayed initiation of escape behavior in response to touch with a 46[o]C probe seen in TrpA11 mutant larvae.

Expression of TrpA1Scer\UAS.cUa under the control of Scer\GAL4TrpA1.PR restores the aversive response of TrpA11 mutant flies to allyl isothiocyanate.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
TrpA1Scer\UAS.cUa
TrpA1UAS.cUa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Unknown
Secondary FlyBase IDs
    References (37)