FlyBase Gene Report: Dmel\adp

General Information

Symbol

Dmel\adp

Species

D. melanogaster

Name

adipose

Annotation Symbol

CG5124

Feature Type

protein_coding_gene

FlyBase ID

FBgn0000057

Gene Model Status

Current

Stock Availability

7 publicly available

Gene Summary

adipose (adp) encodes a protein involved in lipid metabolism and fat storage. [Date last reviewed: 2019-09-12] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Red Book
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

55B9-55B9

Sequence location

2R:18,151,704..18,154,060 [+]

Recombination map

2-84

RefSeq locus

NT_033778 REGION:18151704..18154060

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (8 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (6 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

involved_in lipid metabolic process

inferred from mutant phenotype

(Teague et al., 1986)

involved_in negative regulation of triglyceride storage

inferred from mutant phenotype

(Suh et al., 2007, Hader et al., 2003)

involved_in regulation of lipid storage

inferred from mutant phenotype

(Suh et al., 2007)

involved_in response to desiccation

inferred from mutant phenotype

(Clark and Doane, 1983)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in carbohydrate metabolic process

traceable author statement

(Clark and Doane, 1983)

involved_in lipid metabolic process

traceable author statement

(Clark and Doane, 1983)

involved_in negative regulation of fatty acid biosynthetic process

inferred from biological aspect of ancestor with PANTHER:PTN001811495

(GO Reference Genome Project, 2011-)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

part_of Cul4-RING E3 ubiquitin ligase complex

inferred from biological aspect of ancestor with PANTHER:PTN000400063

(GO Reference Genome Project, 2011-)

is_active_in cytoplasm

inferred from biological aspect of ancestor with PANTHER:PTN000400063

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

adipose (adp) encodes a protein involved in lipid metabolism and fat storage. [Date last reviewed: 2019-09-12]

Phenotypic Description (Red Book; Lindsley and Zimm 1992)

adp60: adipose

Adult fat body hypertrophies as cells become distorted by enormous oil globules. Lipid accumulated at expense of glycogen in fat body; yolk deposition retarded (Doane, 1963, DIS 37: 73-74; Doane, 1980, Evolution 34: 868-74). Lipid content and fatty acid profiles compared for various developmental stages in adp60 and wild type (Teague, Clark, and Doane, 1986, J. Exp. Zool. 240: 95-104). Abnormal fat bodies visible through body wall of 6-day-old and older adults when submerged in 95% alcohol and then water. Corpus allatum of mated females hypertrophies. Females fertile but egg hatchability reduced to 45-90%, depending on residual genome; dorsal appendages of chorion convoluted or fused (King and Koch, 1963, Quant. J. Microscop. Sci. 104: 297-320); adult emergence lowered to 33-85%. (Doane, 1963, DIS. 37: 73-74). Males viable and fertile. Heterozygotes show desiccation tolerance superior to that of wild type or adp60 homozygotes (Clark and Doane, 1983, Hereditas 99: 165-75). RK3.

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\adp for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q7K7W5)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.44

Gene model reviewed during 5.50

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

adp-RA

FBtr0086744

NM_137452

2291

628

adp-RB

FBtr0340288

NM_001299634

2241

628

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

adp-PA

FBpp0085923

71.7

628

6.68

FBpp0309249

71.7

628

6.68

Q7K7W5

NP_001286563

AHN56358

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

628 aa isoforms: adp-PA, adp-PB

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\adp using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

adp_1
adp_2

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

4.59

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage -- adult stage

organism

(Hader et al., 2003)

Additional Descriptive Data

adp transcript is expressed at all stages, with a peak during pupariation.

(Hader et al., 2003)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\adp in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\adp

View exonic expression by tissue for Dmel\adp

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0000057

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

37073/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0000057

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0000057

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0000057

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG5124

Flygut - An atlas of the Drosophila adult midgut

FBgn0000057

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 2 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 7 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of adp

Transgenic constructs containing regulatory region of adp

Aberrations (Deficiencies and Duplications) ( 11 )

Inferred from experimentation ( 11 )

Gene disrupted in

Df(2R)Exel7152

(Ryder, 2004.4.26)

Df(2R)Exel7153

(Ryder, 2004.4.26)

Df(2R)PC4

(Doane, 1999, Doane, 1996, Doane and Dumapias, 1987)

Df(2R)Pcl7B

(Doane, 1999)

Df(2R)Pcl11B

(Doane, 1999, Doane, 1994)

Df(2R)Pcl^XM82

(Doane, 1999)

Df(2R)Pcl-W5

(Doane, 1999, Doane, 1994)

In(2R)Pcl¹¹

(Doane, 1999, Doane, 1994)

Gene not disrupted in

Df(2R)P34

(Doane, 1999)

Df(2R)PC29

(Doane, 1999, Doane, 1996, Doane and Dumapias, 1987)

Df(2R)PC66

(Doane, 1999)

Inferred from location ( 6 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal - all die before end of pupal stage, with Scer\GAL4^fat

adp^UAS.cHa

lethal - all die during embryonic stage | maternal effect

adp⁶⁰

viable

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

adp^GD11544

viable, with Scer\GAL4^elav-C155

adp^UAS.cHa

viable, with Scer\GAL4^pnr-MD237

adp^GD11544

Sterility

Allele

female fertile

adp⁶⁰

fertile

fertile, with Scer\GAL4^elav-C155

adp^UAS.cHa

male fertile

adp⁶⁰

Other Phenotypes

Allele

abnormal locomotor behavior | recessive

adp⁶⁰

abnormal starvation stress response | dominant

adp⁶⁰

abnormal starvation stress response | recessive

adp⁶⁰

abnormal stress response | adult stage

adp⁶⁰

decreased size | larval stage, with Scer\GAL4^insc-Mz1407

adp^HMC06600

decreased size | larval stage, with Scer\GAL4^nSyb.PP

adp^HMC06600

some die during embryonic stage | maternal effect

adp⁶⁰

some die during pupal stage, with Scer\GAL4^fat

adp^UAS.cHa

Phenotype manifest in

Allele

adult corpus allatum

adp⁶⁰

adult corpus allatum | female

adp⁶⁰

adult fat body

adp⁶⁰

dorsal appendage

adp⁶⁰

embryonic/larval fat body, with Scer\GAL4^fat

adp^UAS.cHa

fat body, with Scer\GAL4^DcG

adp^UAS.cHa

fat body, with Scer\GAL4^FBI-19

adp^UAS.cHa

larva

adp¹

larval brain | larval stage, with Scer\GAL4^insc-Mz1407

adp^HMC06600

larval brain | larval stage, with Scer\GAL4^nSyb.PP

adp^HMC06600

lipid droplet

adp⁶⁰

lipid droplet | larval stage

adp¹

oocyte

adp⁶⁰

yolk

adp⁶⁰

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (43)

Hsap\WDTC1

14 of 14

Yes

Hsap\DCAF6

4 of 14

Yes

3 of 14

3 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (26)

Rnor\Wdtc1

14 of 14

Yes

Rnor\Dcaf6

4 of 14

Yes

3 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (29)

Mmus\Wdtc1

14 of 14

Yes

Mmus\Dcaf6

3 of 14

Yes

3 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Xenopus tropicalis (Western clawed frog) (28)

Xtro\wdtc1

8 of 13

Yes

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Danio rerio (Zebrafish) (33)

Drer\wdtc1

14 of 14

Yes

Drer\dcaf6

3 of 14

Yes

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\zc3h7bb

1 of 14

Yes

Drer\zgc:123010

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (18)

Cele\adpr-1

13 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (27)

Agam\AgaP_AGAP003346

12 of 12

Yes

Agam\AgaP_AGAP012877

7 of 12

Yes

Agam\AgaP_AGAP000981

4 of 12

Yes

3 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (37)

Atha\ASG2

13 of 13

Yes

3 of 13

3 of 13

3 of 13

1 of 13

Yes

Atha\AT1G23030

1 of 13

Atha\AT1G48870

1 of 13

Atha\AT1G56040

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (6)

Scer\CDC40

1 of 13

Yes

Scer\CNS1

1 of 13

Yes

Scer\PFS2

1 of 13

Yes

Scer\PPT1

1 of 13

Yes

Scer\RSA4

1 of 13

Yes

Scer\SGT2

1 of 13

Yes

Schizosaccharomyces pombe (Fission yeast) (7)

Spom\iqw1

6 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:adp. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (24)

CG8001

5 of 13

CG42233

4 of 13

ago

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Sgt

1 of 13

Stip1

1 of 13

STUB1

1 of 13

sxc

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

wds

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

obesity, susceptibility to (postulated), WDTC1-related

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Allele

Disease

Evidence

References

adp⁶⁰

model of obesity

CEA

(Suh et al., 2007, Hader et al., 2003)

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

WDTC1; WD and tetratricopeptide repeats 1

14 of 14

619763

DCAF6; DDB1 and CUL4 associated factor 6

4 of 14

610494

DCAF8L1; DDB1 and CUL4 associated factor 8 like 1

3 of 14

DCAF8L2; DDB1 and CUL4 associated factor 8 like 2

3 of 14

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0000057

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Neddylation

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

Q7K7W5

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-84

Cytogenetic map

55B9-55B9

Sequence location

2R:18,151,704..18,154,060 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

55B9-55B9

Limits computationally determined from genome sequence between P{PZ}Hsf⁰³⁰⁹¹&P{EP}Dgp-1^EP731 and P{PZ}sbb⁰⁴⁵²⁵&P{EP}EP1081^EP1081

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-84

(FlyBase, 2016)

2-88.7

(Comeron et al., 2012)

2-83.4

(Doane, 1996, Doane, 1996.8.2)

2-84.3

(Doane, 1994)

2-83

(Doane, 1963, Counce, 1960)

Left of (cM)

mama

(Doane, 1999, Doane, 1999.3.16, Doane, 1999.3.19)

Right of (cM)

Pcl
stau

(Doane, 1999, Doane, 1999.3.19)

(Doane, 1999)

pAbp

(Doane, 1999.3.19)

(Doane and Clark, 1984)

Notes

Map position in error: see Doane, 1996.8.2, personal communication.

(Doane, 1994)

Stocks and Reagents

Stocks (7)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

606483

w¹¹¹⁸; adp¹

81794

y¹ v¹; P{TKO.GS04840}attP40

604822

y¹ v¹; P{SAM.dCas9.GS06175}attP40

80364

y¹ sc^* v¹ sev²¹; P{TRiP.HMC06600}attP40

NIG-Fly

2RG-0390

y² VhaAC39-1^cho-1 v¹; P{U6-adp.NIG.sgRNA}attP40/CyO

VDRC

v22008

w¹¹¹⁸ P{GD11544}v22008

v22010

w¹¹¹⁸ P{GD11544}v22010

Genomic Clones (20)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (48)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

AT17348

Other clones

FI19321

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0000057

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0000057

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Mutants have hypertophied adult fat body, due to accumulation of lipid. Adult corpora allata may hypertrophy.

Relationship to Other Genes

Source for database merge of

Source for merge of: adp CG5124

(FlyBase, 1996-)

Source for merge of: adp anon-WO0196371.27

(FlyBase, 1996-)

Additional comments

PpY-55A and adp are different genes.

(Doane, 1999)

Source for merge of adp CG5124 was sequence comparison ( date:030717 ).

(FlyBase, 1996-)

Source for merge of adp anon-WO0196371.27 was sequence comparison ( date:051113 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

Adp

(Toprak et al., 2020)

CG5124

(National Institute of Genetics Fly Stocks, 2022-, Perkins et al., 2009, Lai et al., 2007, Hader et al., 2003, Broenner et al., 2001)

adp

(Losurdo et al., 2024, Sutton et al., 2024, Carlson et al., 2022, Li et al., 2022, Lehmann, 2018, Transgenic RNAi Project members, 2017-, Heinrichsen and Haddad, 2012, Kamoshida et al., 2012, Kühnlein, 2010, Pospisilik et al., 2010, Reis et al., 2010, Suh et al., 2007, Beller et al., 2006, Hader et al., 2003, Wisotzkey et al., 2003)

anon-WO0196371.1

(Broenner, 2002.2.16)

anon-WO0196371.27

anon-WO0196371.3

(Broenner, 2002.2.16)

Name Synonyms

adipose

(Gáliková and Klepsatel, 2018, Transgenic RNAi Project members, 2017-, Fernández-Ayala et al., 2010, Kühnlein, 2010, Pospisilik et al., 2010, Suh et al., 2007, Hader et al., 2003, Wisotzkey et al., 2003)

Secondary FlyBase IDs

FBgn0034305
FBgn0061182

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 48 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

37073

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q7K7W5

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q7K7W5

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0000057

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

37073/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0000057

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0000057

FlyMine - An integrated database for Drosophila genomics

FBgn0000057

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG5124

MARRVEL_MODEL - MARRVEL (model organism gene)

37073

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0000057

DroID - A comprehensive database of gene and protein interactions.

FBgn0000057

DRSC - Results frm RNAi screens

FBgn0000057

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

adp_1
adp_2

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0000057

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0000057

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG5124

Flygut - An atlas of the Drosophila adult midgut

FBgn0000057

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0000057

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC004375

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Neddylation

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

Q7K7W5

References (72)

The following external sites may use different assemblies or annotations than FlyBase.

4.59

Report Sections