Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mir-1 using the Feature Mapper tool.
mir-1 transcript is expressed in embryonic mesoderm and mesoderm-derived tissues.
Expression increases with time to a peak in the first larval instar, then decreases. Expression levels in male and female adults are comparable to that in first instar larvae.
Northern analysis of 24 microRNAs showed that a number of them were expressed constituitively throughout development.
GBrowse - Visual display of RNA-Seq signalsView Dmel\mir-1 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The annotation for mir-1 has been changed in release 5.31 of the genome annotation, so that instead of representing a mature miRNA it now represents the precursor stem loop pre-miRNA. The symbol of the annotation has been changed from CR32958 to CR43027 to reflect this change.
mir-1 is not required for the formation or physiological function of the larval musculature, but is required for the dramatic post-mitotic growth of larval muscle.
New annotation (CR32958) in release 3 of the genome annotation.