FB2025_01 , released February 20, 2025
Gene Group: ATP-DEPENDENT PROTEIN FOLDING CHAPERONES
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General Information
Name
ATP-DEPENDENT PROTEIN FOLDING CHAPERONES
Species
D. melanogaster
Symbol
PFC
FlyBase ID
FBgg0001743
Date last reviewed
2021-07-15
Number of members
31
Description
Description
ATP-dependent protein folding chaperones use the energy of ATP hydrolysis to bind to a protein or a protein-containing complex and assist the protein folding process.
Notes on Group
Source Material
The ATP-DEPENDENT PROTEIN FOLDING CHAPERONES Gene Group has been compiled using the following publication(s): Kaneko, 2022, Raut et al., 2017, Morrow et al., 2016, Pantzartzi et al., 2013, Ratheesh et al., 2012, Monzo et al., 2010, Takahashi et al., 2010, Arya et al., 2007, Chen et al., 2006, Sarkar and Lakhotia, 2005, Nikolaidis and Nei, 2004, and Easton et al., 2000 .
Key Gene Ontology (GO) terms
Molecular Function
ATP-dependent protein folding chaperone
Biological Process
chaperone-mediated protein folding
Cellular Component
Related Gene Groups
Parent group(s)
ATPASES
Component group(s)
ATYPICAL HEAT SHOCK PROTEIN 70 CHAPERONES
HEAT SHOCK PROTEIN 60 CHAPERONINS
HEAT SHOCK PROTEIN 70 CHAPERONES
HEAT SHOCK PROTEIN 90 CHAPERONES
HEAT SHOCK PROTEIN 100 CHAPERONES
Members (31)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
ATYPICAL HEAT SHOCK PROTEIN 70 CHAPERONES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Grp170
Grp170 co-chaperone
EG:25E8.1
(Ratheesh et al., 2012, Easton et al., 2000)
Hsp110
Heat shock protein 110
Hsc70Cb, Hsc70, dHsp110, l(3)07621, l(3)00082
(Ratheesh et al., 2012, Nikolaidis and Nei, 2004, Easton et al., 2000)
CHAPERONIN CONTAINING TCP-1 COMPLEX
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CCT1
Chaperonin containing TCP1 subunit 1
T-cp1, Tcp1-like, T-cpl, Tcp1, TCP1α
(Monzo et al., 2010)
CCT2
Chaperonin containing TCP1 subunit 2
(Monzo et al., 2010)
CCT3
Chaperonin containing TCP1 subunit 3
Cctgamma, Cctγ, Cctg, vine, Y
(Monzo et al., 2010)
CCT4
Chaperonin containing TCP1 subunit 4
(Monzo et al., 2010)
CCT5
Chaperonin containing TCP1 subunit 5
l(2)06444, T-complex Chaperonin 5
(Monzo et al., 2010)
CCT6
Chaperonin containing TCP1 subunit 6
Tcp-1zeta, l(1)G0057, Tcp-1ζ, lethal (1) G0022, l(1)G0027
(Monzo et al., 2010)
CCT7
Chaperonin containing TCP1 subunit 7
Tcp-1eta, Tcp-1η
(Monzo et al., 2010)
CCT8
Chaperonin containing TCP1 subunit 8
(Monzo et al., 2010)
HEAT SHOCK PROTEIN 60 CHAPERONINS - GROUP I
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Hsp60A
Heat shock protein 60A
Hsp60, l(1)BP5, heat shock protein 60, 12, Hsp 60
(Morrow et al., 2016, Arya et al., 2007, Sarkar and Lakhotia, 2005)
Hsp60B
Heat shock protein 60B
ms(2)21D, Hsp64, Heat shock protein 60 related
(Morrow et al., 2016, Arya et al., 2007, Sarkar and Lakhotia, 2005)
Hsp60C
Heat shock protein 60C
Hsp64
(Morrow et al., 2016, Arya et al., 2007, Sarkar and Lakhotia, 2005)
Hsp60D
Heat shock protein 60D
(Morrow et al., 2016, Arya et al., 2007, Sarkar and Lakhotia, 2005)
HEAT SHOCK PROTEIN 70 CHAPERONES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG7182
(FlyBase, 2017-)
Hsc70-1
Heat shock protein 70 cognate 1
Hsc70, Heat shock protein cognate 1, Hsc1
(Kaneko, 2022, Ratheesh et al., 2012)
Hsc70-2
Heat shock protein 70 cognate 2
Hsc70, hsc2, Hsc70.2, Heat shock protein cognate 2
(Kaneko, 2022, Ratheesh et al., 2012, Nikolaidis and Nei, 2004)
Hsc70-3
Heat shock protein 70 cognate 3
BiP, Hsc3, Hsc70, Grp78, Hsc-70-3
(Kaneko, 2022, Ratheesh et al., 2012, Nikolaidis and Nei, 2004)
Hsc70-4
Heat shock protein 70 cognate 4
Hsc4, Hsc70, Heat shock protein cognate 4, BAP74, Hsp70
(Kaneko, 2022, Ratheesh et al., 2012, Nikolaidis and Nei, 2004)
Hsc70-5
Heat shock protein 70 cognate 5
Hsc5, Hsc70, Heat shock protein cognate 5, l(2)k04907, Heat shock 70 kDa protein cognate 5
(Kaneko, 2022, Ratheesh et al., 2012, Nikolaidis and Nei, 2004)
Hsp68
Heat shock protein 68
68
(Kaneko, 2022, Ratheesh et al., 2012)
Hsp70Aa
Heat shock protein 70 Aa
hsp70, Hsp70A, hsp-70, heat-shock protein 70, hsp70 87A
(Kaneko, 2022, Nikolaidis and Nei, 2004)
Hsp70Ab
Heat shock protein 70 Ab
hsp70, Hsp70A, hsp-70, heat-shock protein 70
(Kaneko, 2022, Ratheesh et al., 2012, Nikolaidis and Nei, 2004)
Hsp70Ba
Heat shock protein 70 Ba
hsp70, Hsp70B, heat-shock protein 70, hsp-70, hsp70 87C
(Kaneko, 2022, Ratheesh et al., 2012, Takahashi et al., 2010, Nikolaidis and Nei, 2004)
Hsp70Bb
Heat shock protein 70 Bb
hsp70, Hsp70B, Hsp70Bc, hsp-70, heat-shock protein 70
(Kaneko, 2022, Ratheesh et al., 2012, Takahashi et al., 2010, Nikolaidis and Nei, 2004)
Hsp70Bbb
Heat shock protein 70 Bbb
Hsp70, hsp70B, heat-shock protein 70
(Kaneko, 2022, Ratheesh et al., 2012, Takahashi et al., 2010)
Hsp70Bc
Heat shock protein 70 Bc
hsp70, Hsp70B, heat-shock protein 70, hsp-70
(Kaneko, 2022, Takahashi et al., 2010, Nikolaidis and Nei, 2004)
HEAT SHOCK PROTEIN 90 CHAPERONES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gp93
Glycoprotein 93
dGRP94
(Pantzartzi et al., 2013, Chen et al., 2006)
Hsp83
Heat shock protein 83
Hsp90, hsp82, l(3)j5C2, E(sev)3A, 83
(Pantzartzi et al., 2013, Chen et al., 2006)
Trap1
Trap1
(Pantzartzi et al., 2013, Chen et al., 2006)
HEAT SHOCK PROTEIN 100 CHAPERONES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
ClpX
Caseinolytic protease chaperone subunit
(Raut et al., 2017)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
PFC
ATP-DEPENDENT PROTEIN FOLDING CHAPERONES
Secondary FlyBase ID(s)
References (14)