FlyBase Allele Report: Dmel\fz[UAS.cAa]

General Information

Symbol

Dmel\fz^UAS.cAa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Adler

FlyBase ID

FBal0060399

Feature type

allele

Associated gene

Dmel\fz

Associated Insertion(s)

Carried in Construct

P{UAS-fz.A}

Also Known As

UAS-Fz, UASFz

Key Links

Transgenic product class

wild_type

(Adler, 1997.3.14)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Adler, 1997.3.14)

Mutagen

in vitro construct

(Axelrod et al., 1998)

Progenitor genotype

Carried in construct

P{UAS-fz.A}

Cytology

Description

UAS regulatory sequences drive expression of fz.

(Adler, 1997.3.14)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell polarity, with Scer\GAL4^ptc-559.1

(Tree et al., 2002)

abnormal planar polarity, with Scer\GAL4^Dll-md23

(Lee and Adler, 2002)

abnormal planar polarity, with Scer\GAL4^dpp.blk1

(Lim et al., 2005, Ma et al., 2003, Axelrod, 2001)

abnormal planar polarity, with Scer\GAL4^dpp.PS

(Buechling et al., 2010)

abnormal planar polarity, with Scer\GAL4^en-e16E

(Hermle et al., 2010)

abnormal planar polarity, with Scer\GAL4^hs.2sev

(Weber et al., 2012, Hermle et al., 2010, Simons et al., 2009, Chung et al., 2007, Ciapponi et al., 2001, Weber et al., 2000, Strutt et al., 1997)

abnormal planar polarity, with Scer\GAL4^hs.2sev, fz^arm.EGFP

(Chung et al., 2007)

abnormal planar polarity, with Scer\GAL4^sev.PM181

(Djiane et al., 2005)

abnormal planar polarity | cell autonomous, with Scer\GAL4^ptc-559.1

(Lu et al., 2010)

abnormal planar polarity | cell non-autonomous, with Scer\GAL4^dpp.blk1

(Chin and Mlodzik, 2013)

visible, with Scer\GAL4^Dll-md23

(Adler et al., 1997)

visible, with Scer\GAL4^dpp.blk1

(Jenny et al., 2005)

visible, with Scer\GAL4^en-e16E

(Franke et al., 2010)

visible, with Scer\GAL4^ptc-559.1

(Usui et al., 1999, Adler et al., 1997)

Phenotype Manifest In

anterior-posterior compartment boundary of the wing blade, with Scer\GAL4^ptc-559.1

(Adler et al., 1997)

border follicle cell, with Scer\GAL4^slbo.2.6

(Bastock and Strutt, 2007)

embryonic/first instar larval cuticle, with Scer\GAL4^{VP16.mat.αTub67C}

(Axelrod et al., 1998)

eye, with Scer\GAL4^hs.2sev

(Simons et al., 2009)

macrochaeta | ectopic, with Scer\GAL4^ap-md52

(Lu et al., 1999)

microchaeta, with Scer\GAL4^ap-md52

(Lu et al., 1999)

ommatidium, with Scer\GAL4^hs.2sev

(Weber et al., 2012, Hermle et al., 2010, Chung et al., 2007, Ciapponi et al., 2001, Weber et al., 2000, Strutt et al., 1997)

ommatidium, with Scer\GAL4^hs.2sev, fz^arm.EGFP

(Chung et al., 2007)

ommatidium, with Scer\GAL4^sev.PM181

(Djiane et al., 2005)

photoreceptor cell R3 | ectopic, with Scer\GAL4^sev.PM181

(Djiane et al., 2005)

photoreceptor cell R3 | increased number, with Scer\GAL4^hs.2sev

(Weber et al., 2000)

photoreceptor cell R4, with Scer\GAL4^hs.2sev

(Weber et al., 2000)

photoreceptor cell R4, with Scer\GAL4^sev.PM181

(Djiane et al., 2005)

sensory mother cell & spindle, with Scer\GAL4^ap-md52

(Lu et al., 1999)

ventral denticle belt, with Scer\GAL4^{VP16.mat.αTub67C}

(Axelrod et al., 1998)

wing & microchaeta, with Scer\GAL4^ptc-559.1

(Adler et al., 1997)

wing & microchaeta | distal, with Scer\GAL4^Dll-md23

(Adler et al., 1997)

wing blade anterior compartment, with Scer\GAL4^ptc-559.1

(Adler et al., 1997)

wing hair, with Scer\GAL4^Dll-md23

(Lee and Adler, 2002)

wing hair, with Scer\GAL4^dpp.blk1

(Jenny et al., 2005, Lim et al., 2005, Axelrod, 2001)

wing hair, with Scer\GAL4^dpp.PS

(Buechling et al., 2010)

wing hair, with Scer\GAL4^en-e16E

(Franke et al., 2010, Hermle et al., 2010)

wing hair, with Scer\GAL4^ptc-559.1

(Lu et al., 2010, Tree et al., 2002)

wing hair & 1st posterior cell, with Scer\GAL4^ptc-559.1

(Usui et al., 1999)

wing hair | cell non-autonomous, with Scer\GAL4^dpp.blk1

(Chin and Mlodzik, 2013)

wing hair | P-stage, with Scer\GAL4^dpp.blk1

(Ma et al., 2003)

Detailed Description

Statement

Reference

Expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^dpp.blk1 in the wing results in non-autonomous hair reorientation, with hairs outside the Scer\GAL4^dpp.blk1 expression domain orienting away from it.

(Chin and Mlodzik, 2013)

Expression of fz^Scer\UAS.cAa using Scer\GAL4^hs.2sev results in ommatidial orientation defects in the eye.

(Weber et al., 2012)

Expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^dpp.PS results in planar polarity defects in the wing.

(Buechling et al., 2010)

Expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^en-e16E results in a very mild multiple wing hair phenotype.

(Franke et al., 2010)

Expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^en-e16E results in wing hairs pointing from the posterior to the anterior compartment in the wing.

Expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^hs.2sev results in planar cell polarity defects in the eye, including a high number of symmetrical ommatidia containing two R3 cells.

(Hermle et al., 2010)

Expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^ptc-559.1 results in wing hairs pointing away from the midline within the expression domain. Outside of the expression domain wing hair polarity is normal.

(Lu et al., 2010)

Expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^hs.2sev results in planar cell polarity defects in the eye.

(Simons et al., 2009)

Expression of fz^Scer\UAS.cAa in the border cells under the control of Scer\GAL4^slbo.2.6 delays border cell migration. A reduction in the number of large actin-protrusions from the border cell cluster compared to wild-type clusters is observed.

(Bastock and Strutt, 2007)

Expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^hs.2sev results in planar polarity defects in the eye; misrotated ommatidia and symmetrical nonchiral ommatidia are seen (only 44.9% of ommatidia are correctly rotated).

The planar polarity defects seen in the eyes of animals expressing fz^Scer\UAS.cAa under the control of Scer\GAL4^hs.2sev are almost completely suppressed by fz³⁰ (76.0% of ommatidia are correctly rotated).

Only 30.3% of ommatidia are correctly rotated in flies expressing fz^Scer\UAS.cAa under the control of Scer\GAL4^hs.2sev and also co-expressing fz^{arm.T:Avic\GFP-EGFP}.

(Chung et al., 2007)

The ommatidia of fz^Scer\UAS.cAa; Scer\GAL4^sev.PM181 adult eyes have random chirality and some are symmetrical, with two R3 photoreceptors in place of an R3/R4 pair.

(Djiane et al., 2005)

Expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^dpp.blk1 in a stripe along the proximo-distal axis of the wing results in a reorientation of wing hairs, which now point laterally away from the expression domain.

(Jenny et al., 2005)

Expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^dpp.blk1 results in reorientation of wing hairs away from the domain of fz expression.

(Lim et al., 2005)

fz^Scer\UAS.cAa; Scer\GAL4^dpp.blk1 flies have a zone extending anterior to the dpp expression domain in which wing hairs point away from the fz overexpressing cells.

(Ma et al., 2003)

When expression is driven by Scer\GAL4^Dll-md23, such that fz expression decreases away from the distal part of the wing, the wing hairs point proximally, instead of distally.

(Lee and Adler, 2002)

When fz^Scer\UAS.cAa is driven by Scer\GAL4^ptc-559.1 in a stripe along the proximal distal axis of the wing, a reorganized polarity results in those cells, that is perpendicular to the normal axis. The wing hairs in the region between wing vein L3 and L4, distal to the anterior crossvein point away from the midline of the wing, unlike wild-type wings, where the wing hairs point distally.

(Tree et al., 2002)

Expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^dpp.blk1 in the wing results in reorientation of the hairs from high to low levels of fz expression.

(Axelrod, 2001)

When fz^Scer\UAS.cAa is driven by Scer\GAL4^hs.2sev, planar polarity defects are seen in the ommatidia.

(Ciapponi et al., 2001)

Expression of fz^Scer\UAS.cAa driven by Scer\GAL4^109(2)80 does not give rise to any detectable dendritic phenotypes.

(Gao et al., 2000)

When expression is driven by Scer\GAL4^hs.2sev, ommatidia are often mis-rotated and show chirality defects. Most of the symmetrical clusters are R3/R3 symmetrical.

(Weber et al., 2000)

fz^Scer\UAS.cAa driven by Scer\GAL4^ap-md52 disrupts the planar polarity of bristles in the notum, primarily affecting microchaetae. Induction of ectopic scutellar bristles are also seen about 80% of the time. In the pupal notum of flies expressing fz^Scer\UAS.cAa driven by Scer\GAL4^ap-md52, the spindle orientations of the Sensory organ precursors (SOP) become randomized.

(Lu et al., 1999)

When expressed in the wing under the control of Scer\GAL4^ptc-559.1, wing hairs are orientated away from the highest point of the fz gradient.

(Usui et al., 1999)

Embryos expressing fz^Scer\UAS.cAa under the control of Scer\GAL4^{mat.αTub67C.T:Hsim\VP16} have a lawn of denticles phenotype.

(Axelrod et al., 1998)

Scer\GAL4^Dll-md23-mediated expression causes a region of reversed polarity near the distal end of the wing. Scer\GAL4^ptc-559.1-mediated expression causes a region of reverse polarity in anterior compartment cells along the anterior-posterior compartment border.

(Adler et al., 1997)

Causes a tissue polarity defect when expressed in a subset of photoreceptors in the developing eye using Scer\GAL4^hs.2sev; ommatidia frequently show abnormal rotation and chirality.

(Strutt et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

fz^UAS.cAa has abnormal planar polarity phenotype, enhanceable by Scer\GAL4^hs.2sev, fz^UAS.cAa

(Weber et al., 2012)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, enhanceable by ATP6AP2^UAS.mCherry, Scer\GAL4^hs.2sev

(Hermle et al., 2010)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, enhanceable by tow^UAS.cCa/Scer\GAL4^hs.2sev

(Chung et al., 2007)

Scer\GAL4^dpp.blk1, fz^UAS.cAa has abnormal planar polarity phenotype, enhanceable | somatic clone by ft^G-rv

(Ma et al., 2003)

Suppressed by

Statement

Reference

Scer\GAL4^dpp.blk1, fz^UAS.cAa has abnormal planar polarity | cell non-autonomous phenotype, suppressible by fw^GD3327/Scer\GAL4^dpp.blk1

(Chin and Mlodzik, 2013)

Scer\GAL4^dpp.PS, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible | partially by ATP6AP2^EY03616

(Buechling et al., 2010)

Scer\GAL4^dpp.PS, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible | partially by ATP6AP2^5-HA-1890

(Buechling et al., 2010)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible | partially by ATP6AP2^EY03616/CG8444[+]

(Hermle et al., 2010)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible | partially by ATP6AP2^KK107676, Scer\GAL4^hs.2sev

(Hermle et al., 2010)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible | partially by Nhe2^RNAi.UAS.WIZ/Nhe2[+]/Nhe2¹, Scer\GAL4^hs.2sev

(Simons et al., 2009)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible | partially by tow[+]/tow⁷⁵⁴

(Chung et al., 2007)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible | partially by In(3L)tow^fz/+

(Chung et al., 2007)

Scer\GAL4^dpp.blk1, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible by Wnt4^UAS.cGa/Scer\GAL4^dpp.blk1

(Lim et al., 2005)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible by kay^C-Ala.UAS/Scer\GAL4^hs.2sev

(Ciapponi et al., 2001)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible by Scer\GAL4^hs.2sev/kay^N-Ala.UAS

(Ciapponi et al., 2001)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible by kay^pan-Ala.UAS/Scer\GAL4^hs.2sev

(Ciapponi et al., 2001)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible by Scer\GAL4^hs.2sev/kay²

(Ciapponi et al., 2001)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible | partially by +/Df(2R)E73

(Weber et al., 2000)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible | partially by Jra^IA109/Jra[+]

(Weber et al., 2000)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible | partially by Jra^76-19/Jra[+]

(Weber et al., 2000)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible by Rho1^k07903

(Strutt et al., 1997)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible by dsh³

(Strutt et al., 1997)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible by Rho1^k07236

(Strutt et al., 1997)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible by bsk¹

(Strutt et al., 1997)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, suppressible by bsk²

(Strutt et al., 1997)

NOT suppressed by

Statement

Reference

Scer\GAL4^dpp.PS, fz^UAS.cAa has abnormal planar polarity phenotype, non-suppressible by ATP6AP2^{EY03616-excΔ}

(Buechling et al., 2010)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, non-suppressible by ATP6AP2^EY03616-ex

(Hermle et al., 2010)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, non-suppressible by Scer\GAL4^hs.2sev/kay^UAS.cEa

(Ciapponi et al., 2001)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, non-suppressible by rl¹⁰

(Strutt et al., 1997)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, non-suppressible by pk^pk-sple-13

(Strutt et al., 1997)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, non-suppressible by nmo^E33

(Strutt et al., 1997)

Scer\GAL4^hs.2sev, fz^UAS.cAa has abnormal planar polarity phenotype, non-suppressible by wg^l-17

(Strutt et al., 1997)

Enhancer of

Statement

Reference

Scer\GAL4^hs.2sev, fz^UAS.cAa is an enhancer of abnormal planar polarity phenotype of fz^UAS.cAa

(Weber et al., 2012)

Scer\GAL4^en-e16E/fz^UAS.cAa is an enhancer of visible phenotype of Scer\GAL4^en-e16E, zip^Rod.UAS.GFP

(Franke et al., 2010)

Suppressor of

Statement

Reference

fz^UAS.cAa/Scer\GAL4^Dll-md23 is a suppressor of abnormal planar polarity phenotype of in¹

(Lee and Adler, 2002)

Other

Statement

Reference

Scer\GAL4^en-e16E, fz^UAS.cAa, zip^Rod.UAS.GFP has abnormal planar polarity phenotype

(Franke et al., 2010)

Phenotype Manifest In

Enhanced by

Statement

Reference

fz^UAS.cAa has ommatidium phenotype, enhanceable by Scer\GAL4^hs.2sev, fz^UAS.cAa

(Weber et al., 2012)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, enhanceable by ATP6AP2^UAS.mCherry, Scer\GAL4^hs.2sev

(Hermle et al., 2010)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, enhanceable by tow^UAS.cCa/Scer\GAL4^hs.2sev

(Chung et al., 2007)

Scer\GAL4^dpp.blk1, fz^UAS.cAa has wing hair | P-stage | anterior phenotype, enhanceable | somatic clone by ft^G-rv

(Ma et al., 2003)

Suppressed by

Statement

Reference

Scer\GAL4^dpp.blk1, fz^UAS.cAa has wing hair | cell non-autonomous phenotype, suppressible by fw^GD3327/Scer\GAL4^dpp.blk1

(Chin and Mlodzik, 2013)

Scer\GAL4^dpp.PS, fz^UAS.cAa has wing hair phenotype, suppressible | partially by ATP6AP2^EY03616

(Buechling et al., 2010)

Scer\GAL4^dpp.PS, fz^UAS.cAa has wing hair phenotype, suppressible | partially by ATP6AP2^5-HA-1890

(Buechling et al., 2010)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, suppressible | partially by ATP6AP2^EY03616/CG8444[+]

(Hermle et al., 2010)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, suppressible | partially by ATP6AP2^KK107676, Scer\GAL4^hs.2sev

(Hermle et al., 2010)

Scer\GAL4^hs.2sev, fz^UAS.cAa has eye phenotype, suppressible | partially by Nhe2^RNAi.UAS.WIZ/Nhe2[+]/Nhe2¹, Scer\GAL4^hs.2sev

(Simons et al., 2009)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, suppressible | partially by tow[+]/tow⁷⁵⁴

(Chung et al., 2007)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, suppressible | partially by In(3L)tow^fz/+

(Chung et al., 2007)

Scer\GAL4^dpp.blk1, fz^UAS.cAa has wing hair phenotype, suppressible by Wnt4^UAS.cGa/Scer\GAL4^dpp.blk1

(Lim et al., 2005)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, suppressible by kay^C-Ala.UAS/Scer\GAL4^hs.2sev

(Ciapponi et al., 2001)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, suppressible by Scer\GAL4^hs.2sev/kay^N-Ala.UAS

(Ciapponi et al., 2001)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, suppressible by kay^pan-Ala.UAS/Scer\GAL4^hs.2sev

(Ciapponi et al., 2001)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, suppressible by Scer\GAL4^hs.2sev/kay²

(Ciapponi et al., 2001)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, suppressible | partially by +/Df(2R)E73

(Weber et al., 2000)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, suppressible | partially by Jra^76-19/Jra[+]

(Weber et al., 2000)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, suppressible | partially by Jra^IA109/Jra[+]

(Weber et al., 2000)

Scer\GAL4^hs.2sev, fz^UAS.cAa has photoreceptor cell R4 phenotype, suppressible | partially by +/Df(2R)E73

(Weber et al., 2000)

Scer\GAL4^hs.2sev, fz^UAS.cAa has photoreceptor cell R4 phenotype, suppressible | partially by Jra^76-19/Jra[+]

(Weber et al., 2000)

Scer\GAL4^hs.2sev, fz^UAS.cAa has photoreceptor cell R4 phenotype, suppressible | partially by Jra^IA109/Jra[+]

(Weber et al., 2000)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, suppressible by Rho1^k07903

(Strutt et al., 1997)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, suppressible by dsh³

(Strutt et al., 1997)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, suppressible by Rho1^k07236

(Strutt et al., 1997)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, suppressible by bsk¹

(Strutt et al., 1997)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, suppressible by bsk²

(Strutt et al., 1997)

NOT suppressed by

Statement

Reference

Scer\GAL4^dpp.PS, fz^UAS.cAa has wing hair phenotype, non-suppressible by ATP6AP2^{EY03616-excΔ}

(Buechling et al., 2010)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, non-suppressible by ATP6AP2^EY03616-ex

(Hermle et al., 2010)

Scer\GAL4^hs.2sev, fz^UAS.cAa has ommatidium phenotype, non-suppressible by Scer\GAL4^hs.2sev/kay^UAS.cEa

(Ciapponi et al., 2001)

Enhancer of

Statement

Reference

Scer\GAL4^hs.2sev, fz^UAS.cAa is an enhancer of ommatidium phenotype of fz^UAS.cAa

(Weber et al., 2012)

Scer\GAL4^en-e16E/fz^UAS.cAa is an enhancer of wing hair | increased number phenotype of Scer\GAL4^en-e16E, zip^Rod.UAS.GFP

(Franke et al., 2010)

Suppressor of

Statement

Reference

fz^UAS.cAa/Scer\GAL4^Dll-md23 is a suppressor of wing hair & 1st posterior cell phenotype of in¹

(Lee and Adler, 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of fw^GD3327 suppresses the non-autonomous hair reorientation caused by expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^dpp.blk1 in the wing.

(Chin and Mlodzik, 2013)

Co-expression of gish^GD10588 with fz^Scer\UAS.cAa under the control of Scer\GAL4^hs.2sev enhances the ommatidial rotation defects induced by Scer\GAL4^hs.2sev>fz^Scer\UAS.cAa.

(Weber et al., 2012)

The planar polarity defects in the wing caused by expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^dpp.PS are partially suppressed by VhaM8.9^EY03616 or VhaM8.9^5-HA-1890, but are not suppressed by VhaM8.9^{EY03616-excΔ}.

(Buechling et al., 2010)

Co-expression of fz^Scer\UAS.cAa enhances the penetrance of the multiple wing hair phenotype caused by expression of zip^{Rod.Scer\UAS.T:Avic\GFP} under the control of Scer\GAL4^en-e16E. In addition, the double mutant wings also show polarity defects.

(Franke et al., 2010)

The planar polarity defects in the eye which are caused by expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^hs.2sev are partially suppressed by VhaM8.9^EY03616/+ or by co-expression of VhaM8.9^KK107676, but are not suppressed by VhaM8.9^EY03616-ex.

Co-expression of VhaM8.9^{Scer\UAS.T:Disc\RFP-mCherry} enhances the planar polarity defects in the eye which are caused by expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^hs.2sev.

(Hermle et al., 2010)

The planar cell polarity defects in the eye that are caused by expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^hs.2sev are partially suppressed if the flies also simultaneously co-express Nhe2^{dsRNA.Scer\UAS.WIZ} and carry Nhe2¹/+.

(Simons et al., 2009)

The planar polarity defects seen in the eyes of animals expressing fz^Scer\UAS.cAa under the control of Scer\GAL4^hs.2sev are almost completely suppressed by tow⁷⁵⁴/+ (79.7% of ommatidia are correctly rotated) or In(3L)tow^fz/+ (79.0% of ommatidia are correctly rotated).

The planar polarity defects seen in the eyes of animals expressing fz^Scer\UAS.cAa under the control of Scer\GAL4^hs.2sev are enhanced by co-expression of tow^Scer\UAS.cCa (only 26.4% of ommatidia are correctly rotated).

(Chung et al., 2007)

Co-expression of Wnt4^Scer\UAS.cGa suppresses the change in wing hair polarity caused by expression of fz^Scer\UAS.cAa under the control of Scer\GAL4^dpp.blk1.

(Lim et al., 2005)

fz^Scer\UAS.cAa; Scer\GAL4^dpp.blk1 flies have a zone extending anterior to the dpp expression domain in which wing hairs point away from the fz overexpressing cells. When such wings have somatic clones of ft^G-rv in the anterior of the wing, this zone enlarges to fill the clone.

(Ma et al., 2003)

The planar polarity defect in dsh¹ wings that are expressing fz^Scer\UAS.cAa under the control of Scer\GAL4^71B is indistinguishable from the dsh¹ single mutant phenotype.

(Rulifson et al., 2000)

The tissue polarity phenotype caused by expression of fz^Scer\UAS.cAa using Scer\GAL4^hs.2sev is dominantly suppressed by fz¹, dsh³, Rho1^k07236, Rho1^k07903, bsk¹ and bsk², but is not affected by rl¹⁰, pk^pk-sple-13, nmo^E33 or wg^l-17.

(Strutt et al., 1997)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescued by

fz^UAS.cAa is partially rescued by Scer\GAL4^hs.2sev/fz¹

(Strutt et al., 1997)

Rescues

Scer\GAL4^da.G32/fz^UAS.cAa rescues fz²¹

(Bhanot et al., 1999)

Scer\GAL4^da.G32/fz^UAS.cAa rescues fz²³

(Bhanot et al., 1999)

Comments

Rescues the embryonic cuticle phenotype of double mutants of fz²¹ or fz²³ with Df(3L)fz2.

(Bhanot et al., 1999)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

fz^Scer\UAS.cAa

fz^UAS.cAa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Adler

(Adler, 1997.3.14)

Secondary FlyBase IDs

References (35)

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