Gene model reviewed during 5.47
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.53
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Map205 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Map205 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Map205 CG1483
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Area matching Drosophila MAP gene Acc. No. X54061.
An antibody against Map205 has been used to clone yeast genes encoding microtubule associated proteins from a yeast cDNA expression library.
The influence of Map205 on the expression and organisation of tubulin in CHO cells and the effect of the protein on tubulin monomer-polymer pools is compared to these properties of human MAP and tau proteins.
Map205 has been cloned and sequenced. Deletion analysis has identified a 232 amino acid region within the Map205 protein (from amino acid 723 to 955) which is necessary for full microtubule-binding activity. The activity of the Map205 protein may be regulated by alternative splicing and phosphorylation.
Encodes a 205kD microtubule-associated protein, which by immunostaining can be localized to cytoplasmic microtubules and to the mitotic spindle.