capping protein β, capping protein, burned, CapZ, Cap2
Gene model reviewed during 5.45
276 (aa); 32 (kD observed)
Heterodimer of an alpha and a beta subunit.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\cpb using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\cpb in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: cpb burned
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a phenotype when assayed in Kc167 and S2R+ cells: increased or polarized (uneven) accumulation of F-actin.
dsRNA made from templates generated with primers directed against this gene is tested in an RNAi screen for effects on actin-based lamella formation.
Identification: in a screen for mutations that cause retinal degeneration in homozygous clones in the eye.
Homozygous clones in the retina are darkly pigmented with no discernible ommatidial organisation. The degeneration has already occurred at eclosion and still occurs in flies reared in complete darkness.
Molecular and genetic characterisation reveals cpb has an essential function during development. cpb is required to regulate actin assembly during the development of specialised structures that depend on actin for their morphology.