tctex-1, dynein light chain; tctex-1, Tctex1, Tctex
Gene model reviewed during 5.44
Gene model reviewed during 5.47
There is only one protein coding transcript and one polypeptide associated with this gene
The cytoplasmic dynein complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Dlc90F using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Dlc90F in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: Tctex l(3)04091
Dlc90F appears to be distinct from other dynein subunits as it is not required for any essential functions in the organism, but only appears to be neccessary in spermatogenesis.
Southern blot analysis indicates that Dlc90F is encoded by a single copy gene and is expressed as a single transcript throughout Drosophila development. Western blot experiments show that the 14kD light chain is co-purified with cytoplasmic dynein from embryos and there exist two isoforms, suggesting a post-translational regulation of the light chain.