FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Gene: Dmel\pod1
Open Close
General Information
Symbol
Dmel\pod1
Species
D. melanogaster
Name
pod1 coronin
Annotation Symbol
CG4532
Feature Type
protein_coding_gene
FlyBase ID
FBgn0029903
Gene Model Status
Current
Stock Availability
10 publicly available
Gene Summary
pod1 (pod1) encodes a microtubule and actin filament binding protein involved in actin cytoskeleton reorganization and axon guidance. [Date last reviewed: 2019-09-19] (FlyBase Gene Snapshot)
All Summaries
Also Known As

coronin

Key Links
Genomic Location
Cytogenetic map
6D2-6D3
Sequence location
Recombination map
1-18
RefSeq locus
NC_004354 REGION:6803684..6813830
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (14 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
enables actin filament binding
inferred from direct assay
(Rothenberg et al., 2003)
enables microtubule binding
inferred from direct assay
(Rothenberg et al., 2003)
enables protein-macromolecule adaptor activity
inferred from direct assay
(Rothenberg et al., 2003)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
enables actin filament binding
inferred from biological aspect of ancestor with PANTHER:PTN000852250
(GO Reference Genome Project, 2011-)
Biological Process (6 terms)
Terms Based on Experimental Evidence (4 terms)
CV Term
Evidence
References
involved_in actin cytoskeleton organization
inferred from direct assay
(Rothenberg et al., 2003)
involved_in AMPA glutamate receptor clustering
inferred from mutant phenotype
(Liebl and Featherstone, 2008)
involved_in axon guidance
inferred from mutant phenotype
(Rothenberg et al., 2003)
involved_in positive regulation of hippo signaling
inferred from genetic interaction with FLYBASE:hpo; FB:FBgn0261456
(Park et al., 2021)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
involved_in actin filament organization
inferred from biological aspect of ancestor with PANTHER:PTN000852250
(GO Reference Genome Project, 2011-)
involved_in cell migration
inferred from biological aspect of ancestor with PANTHER:PTN008507348
(GO Reference Genome Project, 2011-)
involved_in positive regulation of hippo signaling
inferred from biological aspect of ancestor with PANTHER:PTN008507348
(GO Reference Genome Project, 2011-)
Cellular Component (5 terms)
Terms Based on Experimental Evidence (4 terms)
CV Term
Evidence
References
colocalizes_with actin filament
inferred from direct assay
(Rothenberg et al., 2003)
colocalizes_with cytoplasmic microtubule
inferred from direct assay
(Rothenberg et al., 2003)
located_in growth cone
inferred from direct assay
(Rothenberg et al., 2003)
located_in neuromuscular junction
inferred from direct assay
(Liebl and Featherstone, 2008)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
is_active_in plasma membrane
inferred from biological aspect of ancestor with PANTHER:PTN000852250
(GO Reference Genome Project, 2011-)
Gene Group (FlyBase)
Pathway (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
pod1 (pod1) encodes a microtubule and actin filament binding protein involved in actin cytoskeleton reorganization and axon guidance. [Date last reviewed: 2019-09-19]
Pathway (FlyBase)
POSITIVE REGULATORS OF HIPPO SIGNALING PATHWAY -
The Hippo signaling pathway is an intracellular kinase cascade in which hpo kinase in complex with sav, phosphorylates wts kinase which, in turn, phosphorylates yki transcriptional co-activator leading to its cytosolic retention. Positive regulators of the pathway, enhance the cytosolic retention of yki, negatively regulating tissue growth (Adapted from FBrf0224870).
Summary (Interactive Fly)

WD repeat protein - crosslinks actin and microtubules - proper levels of Pod-1 must be maintained in the growth cone for correct axon guidance

Gene Model and Products
Number of Transcripts
7
Number of Unique Polypeptides
3

Please see the JBrowse view of Dmel\pod1 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry D6W4T8)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.50

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.55

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
pod1-RA
FBtr0070964
NM_167091
5798
1074
pod1-RB
FBtr0070965
NM_167092
5797
1074
pod1-RC
FBtr0070966
NM_167093
5737
1074
pod1-RD
FBtr0070967
NM_132124
5837
1074
pod1-RE
FBtr0070968
NM_167094
5806
1074
pod1-RF
FBtr0112956
NM_001103427
6031
1255
pod1-RG
FBtr0308228
NM_001258625
6374
1266
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
pod1-PA
FBpp0070925
119.3
1074
6.75
Q9W3W1
NP_727125
AAN09185
pod1-PB
FBpp0070926
119.3
1074
6.75
Q9W3W1
NP_727126
AAN09186
pod1-PC
FBpp0070927
119.3
1074
6.75
Q9W3W1
NP_727127
AAN09187
pod1-PD
FBpp0070928
119.3
1074
6.75
Q9W3W1
NP_572352
AAF46202
pod1-PE
FBpp0070929
119.3
1074
6.75
Q9W3W1
NP_727128
AAN09188
pod1-PF
FBpp0111869
139.1
1255
6.75
A8JV09
NP_001096897
ABW09349
pod1-PG
FBpp0300548
140.2
1266
6.58
D6W4T8
NP_001245554
AFH07268
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1074 aa isoforms: pod1-PA, pod1-PB, pod1-PC, pod1-PD, pod1-PE
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\pod1 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.75

Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 4 -- 6
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 7 -- 8
antennal anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)
central brain anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)
dorsal head epidermis anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)
visual anlage

Comment: reported as procephalic ectoderm anlage

(Fisher et al., 2012)
anterior endoderm anlage
(Fisher et al., 2012)
hindgut anlage
(Fisher et al., 2012)
posterior endoderm
(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
ventral ectoderm
(Fisher et al., 2012)
embryonic stage 9 -- 10
antennal primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
central brain primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
visual primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
dorsal head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
lateral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
ventral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
anterior endoderm
(Fisher et al., 2012)
foregut primordium
(Fisher et al., 2012)
head mesoderm
(Fisher et al., 2012)
inclusive hindgut primordium
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
posterior endoderm
(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
ventral nerve cord primordium
(Fisher et al., 2012)
embryonic stage 9 -- 12
midline primordium | subset
(Kearney et al., 2004)
embryonic stage 11 -- 12
anterior midgut primordium
(Fisher et al., 2012)
central brain primordium
(Fisher et al., 2012)
embryonic central brain glial cell
(Fisher et al., 2012)
embryonic central brain neuron
(Fisher et al., 2012)
embryonic neuroblast of ventral nerve cord primordium
(Fisher et al., 2012)
head mesoderm
(Fisher et al., 2012)
larval lateral VNC glial cell
(Fisher et al., 2012)
lateral cord neuron
(Fisher et al., 2012)
larval ventral midline glial cell
(Fisher et al., 2012)
posterior midgut primordium
(Fisher et al., 2012)
procephalic neuroblast
(Fisher et al., 2012)
somatic muscle primordium
(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
ventral nerve cord primordium
(Fisher et al., 2012)
embryonic stage 13 -- 16
embryonic brain
(Fisher et al., 2012)
embryonic central brain neuron
(Fisher et al., 2012)
larval muscle system
(Fisher et al., 2012)
larval nervous system
(Fisher et al., 2012)
larval somatic muscle cell
(Fisher et al., 2012)
lateral cord neuron
(Fisher et al., 2012)
sensory nervous system primordium
(Fisher et al., 2012)
ventral midline of embryo
(Fisher et al., 2012)
larval ventral nerve cord
(Fisher et al., 2012)
larval midline neuron
(Kearney et al., 2004)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
colocalizes_with actin filament
inferred from direct assay
(Rothenberg et al., 2003)
colocalizes_with cytoplasmic microtubule
inferred from direct assay
(Rothenberg et al., 2003)
located_in growth cone
inferred from direct assay
(Rothenberg et al., 2003)
located_in neuromuscular junction
inferred from direct assay
(Liebl and Featherstone, 2008)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\pod1 in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 1-3
  • Stages(s) 4-6
  • Stages(s) 7-8
  • Stages(s) 9-10
  • Stages(s) 11-12
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 9 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 9 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of pod1
Transgenic constructs containing regulatory region of pod1
Aberrations (Deficiencies and Duplications) ( 4 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (46)
Hsap\CORO7
14 of 14
Yes
Yes
Hsap\CORO7-PAM16
5 of 14
No
Yes
Hsap\CORO1A
2 of 14
No
No
Hsap\CORO1B
2 of 14
No
No
Hsap\CORO1C
2 of 14
No
No
Hsap\CORO2A
2 of 14
No
No
1  
Hsap\CORO2B
2 of 14
No
No
Hsap\CORO6
2 of 14
No
No
Hsap\APAF1
1 of 14
No
No
Hsap\ATG16L1
1 of 14
No
No
Hsap\BTRC
1 of 14
No
No
1  
Hsap\CDRT1
1 of 14
No
No
Hsap\COPA
1 of 14
No
No
Hsap\COPB2
1 of 14
No
No
Hsap\DAW1
1 of 14
No
No
Hsap\DCAF5
1 of 14
No
No
1  
Hsap\DCAF7
1 of 14
No
No
1  
Hsap\DCAF13
1 of 14
No
No
Hsap\EML4
1 of 14
No
No
Hsap\FBXW10
1 of 14
No
No
Hsap\GEMIN5
1 of 14
No
No
Hsap\GRWD1
1 of 14
No
No
Hsap\KATNB1
1 of 14
No
No
Hsap\NLE1
1 of 14
No
No
Hsap\PAFAH1B1
1 of 14
No
No
1  
Hsap\PEX7
1 of 14
No
No
Hsap\POC1A
1 of 14
No
No
1  
Hsap\POC1B
1 of 14
No
No
1  
Hsap\PWP1
1 of 14
No
No
1  
Hsap\RACK1
1 of 14
No
No
4  
Hsap\RBBP4
1 of 14
No
No
2  
Hsap\RBBP7
1 of 14
No
No
4  
Hsap\TAF5
1 of 14
No
No
Hsap\TAF5L
1 of 14
No
No
Hsap\TBL1X
1 of 14
No
No
1  
Hsap\TBL3
1 of 14
No
No
Hsap\WDR5B
1 of 14
No
No
1  
Hsap\WDR5
1 of 14
No
No
11  
Hsap\WDR17
1 of 14
No
No
Hsap\WDR24
1 of 14
No
No
Hsap\WDR36
1 of 14
No
No
Hsap\WDR44
1 of 14
No
No
Hsap\WDR48
1 of 14
No
No
Hsap\WDSUB1
1 of 14
No
No
Hsap\WSB1
1 of 14
No
No
1  
Hsap\WSB2
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (16)
Rnor\Coro7
14 of 14
Yes
Yes
Rnor\Coro1a
2 of 14
No
No
Rnor\Coro1b
2 of 14
No
No
Rnor\Coro1c
2 of 14
No
No
Rnor\Coro2a
2 of 14
No
No
Rnor\Coro2b
2 of 14
No
No
Rnor\Coro6
2 of 14
No
No
Rnor\Dcaf5
1 of 14
No
No
Rnor\Katnb1
1 of 14
No
No
Rnor\Pex7
1 of 14
No
No
Rnor\Poc1a
1 of 14
No
No
Rnor\Poc1b
1 of 14
No
No
Rnor\Rbbp4
1 of 14
No
No
Rnor\RGD1563620
1 of 14
No
No
Rnor\Wdr5
1 of 14
No
No
Rnor\Wdr24
1 of 14
No
No
Mus musculus (laboratory mouse) (16)
Mmus\Coro7
14 of 14
Yes
Yes
Mmus\Coro1a
2 of 14
No
No
Mmus\Coro1b
2 of 14
No
No
Mmus\Coro1c
2 of 14
No
No
Mmus\Coro2b
2 of 14
No
No
Mmus\Coro6
2 of 14
No
No
Mmus\Coro2a
1 of 14
No
No
Mmus\Dcaf5
1 of 14
No
No
Mmus\Katnb1
1 of 14
No
No
Mmus\Pex7
1 of 14
No
No
Mmus\Poc1b
1 of 14
No
No
Mmus\Rbbp4
1 of 14
No
No
Mmus\Tbl1xr1
1 of 14
No
No
Mmus\Wdr5
1 of 14
No
No
Mmus\Wdr24
1 of 14
No
No
Mmus\Wdr59
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (29)
Xtro\coro7
11 of 13
Yes
Yes
Xtro\coro1c
2 of 13
No
No
Xtro\coro2b
2 of 13
No
No
Xtro\LOC100496364
2 of 13
No
Yes
Xtro\apaf1
1 of 13
No
No
Xtro\copb2
1 of 13
No
No
Xtro\coro1a
1 of 13
No
No
Xtro\coro2a
1 of 13
No
No
Xtro\coro6
1 of 13
No
No
Xtro\daw1
1 of 13
No
No
Xtro\dcaf7
1 of 13
No
No
Xtro\gemin5
1 of 13
No
No
Xtro\grwd1
1 of 13
No
No
Xtro\pafah1b1
1 of 13
No
No
Xtro\pwp1
1 of 13
No
No
Xtro\rack1
1 of 13
No
No
Xtro\rbbp4
1 of 13
No
No
Xtro\rbbp7
1 of 13
No
No
Xtro\slc39a2
1 of 13
No
No
Xtro\snrnp40
1 of 13
No
No
Xtro\taf5l
1 of 13
No
No
Xtro\taf5
1 of 13
No
No
Xtro\wdr5
1 of 13
No
No
Xtro\wdr48
1 of 13
No
No
Xtro\wdr59
1 of 13
No
No
Xtro\wdr83
1 of 13
No
No
Xtro\wdr86
1 of 13
No
No
Xtro\wdsub1
1 of 13
No
Yes
Xtro\wsb1
1 of 13
No
Yes
Danio rerio (Zebrafish) (22)
Drer\coro7
12 of 14
Yes
Yes
Drer\LOC100537938
8 of 14
No
Yes
Drer\coro1a
2 of 14
No
No
Drer\coro1b
2 of 14
No
No
Drer\coro1ca
2 of 14
No
No
Drer\coro1cb
2 of 14
No
No
Drer\coro2aa
2 of 14
No
No
Drer\coro2ab
2 of 14
No
No
Drer\coro2bb
2 of 14
No
No
Drer\coro6
2 of 14
No
No
Drer\coro2ba
1 of 14
No
No
Drer\dcaf5
1 of 14
No
No
Drer\dtl
1 of 14
No
No
Drer\poc1a
1 of 14
No
No
Drer\poc1b
1 of 14
No
No
Drer\rbb4l
1 of 14
No
No
Drer\sec31b
1 of 14
No
No
Drer\tbl1x
1 of 14
No
No
Drer\wdr5
1 of 14
No
No
Drer\wdr24
1 of 14
No
No
Drer\wdr59
1 of 14
No
No
Drer\wsb1
1 of 14
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (19)
Cele\pod-1
13 of 14
Yes
Yes
Cele\cor-1
2 of 14
No
No
Cele\cash-1
1 of 14
No
No
Cele\cdt-2
1 of 14
No
No
Cele\JC8.2
1 of 14
No
No
Cele\lin-23
1 of 14
No
No
Cele\lin-53
1 of 14
No
No
Cele\prp-4
1 of 14
No
No
Cele\rba-1
1 of 14
No
No
Cele\sel-10
1 of 14
No
No
Cele\snrp-40.2
1 of 14
No
No
Cele\swan-1
1 of 14
No
No
Cele\swan-2
1 of 14
No
No
Cele\unc-78
1 of 14
No
No
Cele\wdr-5.1
1 of 14
No
No
Cele\wdr-5.2
1 of 14
No
No
Cele\wdr-5.3
1 of 14
No
No
Cele\Y32H12A.8
1 of 14
No
No
Cele\Y54H5A.1
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (22)
Agam\AgaP_AGAP000930
12 of 12
Yes
Yes
Agam\AgaP_AGAP005891
2 of 12
No
No
Agam\AgaP_AGAP007525
2 of 12
No
No
Agam\AgaP_AGAP000678
1 of 12
No
No
Agam\AgaP_AGAP001159
1 of 12
No
No
Agam\AgaP_AGAP001362
1 of 12
No
No
Agam\AgaP_AGAP002019
1 of 12
No
No
Agam\AgaP_AGAP002776
1 of 12
No
No
Agam\AgaP_AGAP003228
1 of 12
No
No
Agam\AgaP_AGAP003524
1 of 12
No
No
Agam\AgaP_AGAP004768
1 of 12
No
No
Agam\AgaP_AGAP006036
1 of 12
No
No
Agam\AgaP_AGAP006264
1 of 12
No
No
Agam\AgaP_AGAP007125
1 of 12
No
No
Agam\AgaP_AGAP007217
1 of 12
No
No
Agam\AgaP_AGAP007739
1 of 12
No
No
Agam\AgaP_AGAP009506
1 of 12
No
No
Agam\AgaP_AGAP009574
1 of 12
No
No
Agam\AgaP_AGAP010251
1 of 12
No
No
Agam\AgaP_AGAP011678
1 of 12
No
No
Agam\AgaP_AGAP011849
1 of 12
No
No
Agam\AgaP_AGAP012731
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (36)
Atha\AT1G10580
1 of 13
Yes
No
Atha\AT1G18830
1 of 13
Yes
No
Atha\AT1G52360
1 of 13
Yes
No
Atha\AT1G62020
1 of 13
Yes
No
Atha\AT2G19540
1 of 13
Yes
No
Atha\AT2G21390
1 of 13
Yes
No
Atha\AT3G15980
1 of 13
Yes
No
Atha\AT3G63460
1 of 13
Yes
No
Atha\AT4G01860
1 of 13
Yes
No
Atha\AT4G18900
1 of 13
Yes
No
Atha\AT4G18905
1 of 13
Yes
No
Atha\AT4G35370
1 of 13
Yes
No
Atha\AT5G08390
1 of 13
Yes
No
Atha\AT5G23430
1 of 13
Yes
No
Atha\AT5G49430
1 of 13
Yes
No
Atha\AT5G52820
1 of 13
Yes
No
Atha\ATAN11
1 of 13
Yes
No
Atha\FBX2
1 of 13
Yes
No
Atha\FVE
1 of 13
Yes
No
Atha\FY
1 of 13
Yes
No
Atha\FZR3
1 of 13
Yes
No
Atha\HOS15
1 of 13
Yes
No
Atha\LIS
1 of 13
Yes
No
Atha\LST8-2
1 of 13
Yes
No
Atha\LWD2
1 of 13
Yes
No
Atha\MAC3A
1 of 13
Yes
No
Atha\MSI2
1 of 13
Yes
No
Atha\MSI3
1 of 13
Yes
No
Atha\NFC5
1 of 13
Yes
No
Atha\PEX7
1 of 13
Yes
No
Atha\SMU1
1 of 13
Yes
No
Atha\SPA1
1 of 13
Yes
Yes
Atha\TAF5
1 of 13
Yes
No
Atha\TTG1
1 of 13
Yes
No
Atha\WDR5a
1 of 13
Yes
No
Atha\WDR5b
1 of 13
Yes
No
Saccharomyces cerevisiae (Brewer's yeast) (8)
Scer\CRN1
2 of 13
Yes
No
Scer\HAT2
1 of 13
No
No
Scer\PFS2
1 of 13
No
No
Scer\PWP1
1 of 13
No
No
Scer\RPN14
1 of 13
No
No
Scer\RSA4
1 of 13
No
No
Scer\TAF5
1 of 13
No
No
Scer\YPL247C
1 of 13
No
No
Schizosaccharomyces pombe (Fission yeast) (6)
Spom\crn1
1 of 12
Yes
No
Spom\mis16
1 of 12
Yes
No
Spom\prw1
1 of 12
Yes
No
Spom\SPAC4F8.11
1 of 12
Yes
No
Spom\swd3
1 of 12
Yes
No
Spom\utp13
1 of 12
Yes
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:pod1. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (20)
coro
5 of 13
Caf1-55
1 of 13
can
1 of 13
CG6724
1 of 13
CG10931
1 of 13
CstF50
1 of 13
ebi
1 of 13
Gβ5
1 of 13
l(2)09851
1 of 13
nclb
1 of 13
Pex7
1 of 13
Poc1
1 of 13
slmb
1 of 13
Taf5
1 of 13
wap
1 of 13
wda
1 of 13
Wdr24
1 of 13
Wdr33
1 of 13
Wdr59
1 of 13
wds
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Allele
Disease
Evidence
References
pod1HMS02270
model of  obesity
CEA
(Eriksson et al., 2015)
Potential Models Based on Orthology ( 0 )
Human Ortholog
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
CORO7; coronin 7
14 of 14
611668
      CORO7-PAM16; CORO7-PAM16 readthrough
      5 of 14
          Functional Complementation Data
          Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
          Interactions
          Summary of Physical Interactions
          Summary of Genetic Interactions
          Interaction Browsers
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          External Data
          Linkouts
          BioGRID - A database of protein and genetic interactions.
          DroID - A comprehensive database of gene and protein interactions.
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Pathways
          Signaling Pathways (FlyBase)
          Metabolic Pathways
          FlyBase
          External Links
          External Data
          Linkouts
          SignaLink - A signaling pathway resource with multi-layered regulatory networks.
          Class of Gene
          Genomic Location and Detailed Mapping Data
          Chromosome (arm)
          X
          Recombination map
          1-18
          Cytogenetic map
          6D2-6D3
          Sequence location
          FlyBase Computed Cytological Location
          Cytogenetic map
          Evidence for location
          6D2-6D3
          Limits computationally determined from genome sequence between P{EP}C3GEP1613 and P{EP}EP1388EP1388&P{EP}EP1573
          Experimentally Determined Cytological Location
          Cytogenetic map
          Notes
          References
          Experimentally Determined Recombination Data
          Location

          1-18

          (FlyBase, 2016)

          1-19.3

          (Comeron et al., 2012)
          Left of (cM)
          Right of (cM)
          Notes
          Stocks and Reagents
          Stocks (10)
          Genomic Clones (17)
           

          Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

          cDNA Clones (111)
           

          Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

          cDNA clones, fully sequenced
          BDGP DGC clones
          Other clones
          Drosophila Genomics Resource Center cDNA clones

          For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

          cDNA Clones, End Sequenced (ESTs)
          BDGP DGC clones
          Other clones
          RNAi and Array Information
          Linkouts
          DRSC - Results frm RNAi screens
          Antibody Information
          Laboratory Generated Antibodies
           
          Commercially Available Antibodies
           
          Cell Line Information
          Publicly Available Cell Lines
           
            Other Stable Cell Lines
             
              Other Comments

              ChEST reveals this is a target of Mef2.

              (Junion et al., 2005)

              dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.

              (Kiger et al., 2003)

              dsRNA made from templates generated with primers directed against this gene is tested in an RNAi screen for effects on actin-based lamella formation.

              (Rogers et al., 2003)
              Relationship to Other Genes
              Source for database merge of

              Source for merge of: pod1 BEST:LD37601

              (Rana, 2004.7.8)

              Source for merge of: CG4532 BcDNA:LD08951

              (FlyBase, 1996-)
              Additional comments

              Source for merge of CG4532 BcDNA:LD08951 was a shared cDNA ( date:020730 ).

              (FlyBase, 1996-)
              Nomenclature History
              Source for database identify of
              Nomenclature comments
              Etymology
              Synonyms and Secondary IDs (15)
              Datasets (0)
              Study focus (0)
              Experimental Role
              Project
              Project Type
              Title
              Study result (0)
              Result
              Result Type
              Title
              External Crossreferences and Linkouts ( 93 )
              Sequence Crossreferences
              NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
              GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
              GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
              RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
              UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
              UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
              Other crossreferences
              AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
              BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
              DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
              EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
              FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
              FlyMine - An integrated database for Drosophila genomics
              InterPro - A database of protein families, domains and functional sites
              KEGG Genes - Molecular building blocks of life in the genomic space.
              MARRVEL_MODEL - MARRVEL (model organism gene)
              Linkouts
              BioGRID - A database of protein and genetic interactions.
              Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
              DroID - A comprehensive database of gene and protein interactions.
              DRSC - Results frm RNAi screens
              Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
              FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
              FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
              Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
              Flygut - An atlas of the Drosophila adult midgut
              iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
              Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
              MIST (protein-protein) - An integrated Molecular Interaction Database
              SignaLink - A signaling pathway resource with multi-layered regulatory networks.
              References (66)