FlyBase Gene Report: Dmel\Ntf-2

General Information

Symbol

Dmel\Ntf-2

Species

D. melanogaster

Name

Nuclear transport factor-2

Annotation Symbol

CG1740

Feature Type

protein_coding_gene

FlyBase ID

FBgn0031145

Gene Model Status

Current

Stock Availability

10 publicly available

Gene Summary

Nuclear transport factor-2 (Ntf-2) is an essential gene regulating nuclear import. It encodes a protein that binds to the nuclear pore protein encoded by DCTN4-p62 and to the product of Ran and regulates the nuclear import of nuclear localization signal containing proteins. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Interactive Fly

Also Known As

DNTF-2, Ntf2, l(1)G0125, l(1)G0086, l(1)G0428

Key Links

Genomic Location

Cytogenetic map

19E7-19E7

Sequence location

X:21,035,469..21,041,467 [+]

Recombination map

1-65

RefSeq locus

NC_004354 REGION:21035469..21041467

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (5 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables nuclear import signal receptor activity

inferred from biological aspect of ancestor with PANTHER:PTN000289033

(GO Reference Genome Project, 2011-)

Biological Process (3 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in positive regulation of antimicrobial peptide biosynthetic process

inferred from mutant phenotype

(Bhattacharya and Steward, 2002)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in nucleocytoplasmic transport

inferred from electronic annotation with InterPro:IPR045875

(InterPro Project Members, 2004-)

involved_in protein import into nucleus

inferred from biological aspect of ancestor with PANTHER:PTN000289033

(GO Reference Genome Project, 2011-)

Cellular Component (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

part_of nuclear pore central transport channel

inferred from biological aspect of ancestor with PANTHER:PTN000289031

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Ntf-2 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VRD6)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated

Gene model reviewed during 5.46

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.50

Antisense UTR: 3' UTR of one isoform is antisense to CG15449 on opposite strand.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Ntf-2-RA

FBtr0077241

NM_134578

755

130

Ntf-2-RB

FBtr0113007

NM_001103570

1607

129

FBtr0333760

1482

FBtr0333762

3078

130

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Ntf-2-PA

FBpp0076934

14.6

130

5.51

FBpp0111920

14.6

129

5.04

FBpp0305902

9.9

6.96

FBpp0305904

14.6

130

5.51

Q9VRD6

NP_001259750

AGB95588

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

130 aa isoforms: Ntf-2-PA, Ntf-2-PE

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ntf-2 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Ntf-2_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.83

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

organism | faint | ubiquitous

(Fisher et al., 2012)

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 13 -- 16

organism | faint | ubiquitous

(Fisher et al., 2012)

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage -- adult stage

organism

(Bhattacharya and Steward, 2002)

adult stage | female

ovary

(Bhattacharya and Steward, 2002)

RT-PCR

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | male

testis

(Betran and Long, 2003)

adult stage | female

(Betran and Long, 2003)

Additional Descriptive Data

Ntf-2 transcripts are expressed in all stages and tissues studied.

(Betran and Long, 2003)

Ntf-2 is expressed at all stages examined, most strongly in embryos at 0-4 hr AEL, and in the ovaries of adult females. Expression is observed in both male and female adults, with expression levels being much higher in females.

(Bhattacharya and Steward, 2002)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Ntf-2 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Ntf-2

View exonic expression by tissue for Dmel\Ntf-2

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0031145

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

33078/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0031145

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0031145

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0031145

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG1740

Flygut - An atlas of the Drosophila adult midgut

FBgn0031145

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 14 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 9 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Ntf-2

Transgenic constructs containing regulatory region of Ntf-2

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 19 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal | female

lethal | recessive

lethal - all die before end of larval stage

lethal - all die before end of larval stage | recessive

Ntf-2^G0428

lethal - all die during embryonic stage

Ntf-2^G0428

lethal - all die during larval stage, with Scer\GAL4^Mef2.PR

partially lethal, with Scer\GAL4^tin.CΔ4

Ntf-2^GD17755

partially lethal - majority die, with Scer\GAL4^pnr-MD237

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Ntf-2^GD17755

viable | male

Ntf-2^unspecified

Sterility

Allele

female fertile, with Scer\GAL4^nanos.PG

Ntf-2^KK114962

female sterile, with Scer\GAL4^nanos.PG

Ntf-2^GD8604

male fertile

Ntf-2^unspecified

Other Phenotypes

Allele

short lived | heat sensitive, with Scer\GAL4^tin.CΔ4

Ntf-2^GD17755

some die during embryonic stage

Ntf-2^G0428

some die during larval stage

some die during pupal stage, with Scer\GAL4^pnr-MD237

some die during third instar larval stage | recessive

Ntf-2^G0428

visible, with Scer\GAL4^pnr-MD237

visible | recessive

Ntf-2^unspecified

Phenotype manifest in

Allele

eye

mesonotum, with Scer\GAL4^pnr-MD237

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (5)

Hsap\NUTF2

14 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (5)

Rnor\Nutf2

14 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (7)

Mmus\Nutf2

13 of 14

Yes

Mmus\Nutf2-ps1

11 of 14

Yes

Mmus\Nutf2-ps2

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (3)

Xtro\nutf2

11 of 13

Yes

Xtro\g3bp1

1 of 13

Xtro\nxt2

1 of 13

Danio rerio (Zebrafish) (6)

Drer\nutf2

14 of 14

Yes

Drer\nutf2l

13 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (3)

Cele\ran-4

14 of 14

Yes

Cele\gtbp-1

1 of 14

Cele\nxt-1

1 of 14

Anopheles gambiae (African malaria mosquito) (4)

Agam\AgaP_AGAP007024

12 of 12

Yes

Agam\AgaP_AGAP000498

11 of 12

Yes

Agam\AgaP_AGAP000403

1 of 12

Agam\AgaP_AGAP008234

1 of 12

Arabidopsis thaliana (thale-cress) (11)

Atha\NTF2A

13 of 13

Yes

Atha\NTF2B

13 of 13

Yes

Atha\NTL

12 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (1)

Scer\NTF2

13 of 13

Yes

Schizosaccharomyces pombe (Fission yeast) (3)

Spom\nxt2

12 of 12

Yes

Spom\nxt1

1 of 12

Spom\nxt3

1 of 12

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Ntf-2. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (3)

Ntf-2r

13 of 13

Nxt1

3 of 13

rin

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

NUTF2; nuclear transport factor 2

14 of 14

605813

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Ntf-2

two hybrid

(Hu et al., 2017.6.13)

Ntf-2 - AP-2α

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - AP-2σ

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - AnxB10

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Ar1

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Ar2

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Bacc

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - CG14715

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - CG2004

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - CG2852

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - CG3630

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - CG42557

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - CG8993

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Calr

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Cyp1

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Df31

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Eno

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Fkbp14

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Glo1

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - GstO3

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - HINT1

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Ho

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Moe

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Nlp

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Ntf-2r

two hybrid

(Hu et al., 2017.6.13)

Ntf-2 - Pdi

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Prx6c

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - RhoGDI

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Sh3β

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Sod1

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Sumo

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Tango2

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Trx2

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - Trxr1

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - awd

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - capt

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - cib

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - fabp

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - mtSSB

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - regucalcin

experimental knowledge based

(Guruharsha et al., 2011)

Ntf-2 - scu

experimental knowledge based

(Guruharsha et al., 2011)

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

59365

DroID - A comprehensive database of gene and protein interactions.

FBgn0031145

MIST (protein-protein) - An integrated Molecular Interaction Database

33078

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

1-65

Cytogenetic map

19E7-19E7

Sequence location

X:21,035,469..21,041,467 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

19E7-19E7

Limits computationally determined from genome sequence between P{EP}CG1702^EP1525 and P{EP}EP1465&P{EP}CG1486^EP1192

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

19E-19E

(determined by in situ hybridisation)

(Peter et al., 2002, Schäfer et al., 1999.6.15, Schäfer et al., 1999.12.2)

Experimentally Determined Recombination Data

Location

1-65

(FlyBase, 2016)

1-65.7

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (10)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

28633

y¹ v¹; P{TRiP.JF03048}attP2

52052

y¹ w^* Mi{MIC}Ntf-2^MI08610

98896

y¹ w¹; P{TKO-UAS.GS06093}attP40/CyO

602225

w^* TI{CRIMIC.TG4.0}Ntf-2^{CR70900-TG4.0}

603887

w¹¹¹⁸ P{SX4.lexA::HG}Ntf-2^S21-19/FM7a

11913

w^67c23 P{lacW}Ntf-2^G0428/FM7c, sn⁺

35636

y¹ sc^* v¹ sev²¹; P{TRiP.GL00483}attP2/TM3, Sb¹

1740R-1

v110108

v49848

w¹¹¹⁸; P{GD17755}v49848

Genomic Clones (12)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (50)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

GM08921

Other clones

DPiM_GM08921

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0031145

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0031145

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

The Ntf-2 product is a part of a multiprotein complex that facilitates import of the Rel factors into the nucleus.

(Bhattacharya and Steward, 2001)

Relationship to Other Genes

Source for database merge of

Source for merge of: Ntf-2 l(1)G0125 l(1)G0337 l(1)G0086 l(1)G0428

(Peter et al., 2002)

Source for merge of: Ntf-2 BcDNA:GM08921

(FlyBase, 1996-)

Additional comments

The Ntf-2r gene may have been derived from the Ntf-2 gene by retroposition.

(Dai et al., 2006)

The Ntf-2r gene may be derived from the Ntf-2 gene by retroposition.

(Betran et al., 2002)

Source for merge of Ntf-2 BcDNA:GM08921 was a shared cDNA ( date:020730 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Source for identity of: Ntf-2 CG1740

(Bhattacharya, 2001.3.7)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (17)

Reported As

Symbol Synonym

BcDNA:GM08921

CG1740

(Chen et al., 2012, Ni et al., 2011.7.19, Zhan et al., 2011, Zhang et al., 2011, Zhang et al., 2010, Keleman et al., 2009.8.5, Mason and Goldfarb, 2009, Pan and Zhang, 2009, Perkins et al., 2009, Dai et al., 2006, Bourbon et al., 2002)

DNTF-2

(Mason and Goldfarb, 2009, Moussian and Roth, 2005, Bhattacharya and Steward, 2002, Bhattacharya and Steward, 2001)

Dntf-2

(Tracy et al., 2010, Bai et al., 2007, Betran and Long, 2003)

Dntf2

(Betran et al., 2002)

NTF-2

(Timinszky et al., 2002, Bhattacharya and Steward, 2001)

Ntf-2

(Huang et al., 2024, Bosch et al., 2023, Pan et al., 2023, Kim et al., 2021, Mirsalehi et al., 2021, Ohhara et al., 2021, Su et al., 2021, Park et al., 2020, Gene Disruption Project members, 2018-, Hu et al., 2017.6.13, Transgenic RNAi Project members, 2017-, Bischof and FlyORF project members, 2014.6.20, Czech et al., 2013, Japanese National Institute of Genetics, 2012.5.21, Skora and Spradling, 2010, Tracy et al., 2010, Langille and Clark, 2007, Langille and Clark, 2007, Liebl and Featherstone, 2005)

Ntf2

(Ge et al., 2021, Faisal et al., 2014, Hill-Burns and Clark, 2009)

dmNTF2

(Black et al., 1999)

l(1)G0086

(Schäfer et al., 1999.6.15)

l(1)G0125

(Schäfer et al., 1999.6.15)

l(1)G0337

(Schäfer et al., 1999.12.2)

l(1)G0428

(Schäfer et al., 1999.6.15)

ntf-2

(Belmonte et al., 2019, Mason and Goldfarb, 2009, Minakhina et al., 2005, Bhattacharya and Steward, 2002)

ntf2

(Minakhina et al., 2004, Myers et al., 2003)

Name Synonyms

Nuclear transport factor-2

(Betran and Long, 2003)

nuclear transport factor-2

(Bhattacharya and Steward, 2002)

Secondary FlyBase IDs

FBgn0027201
FBgn0027301
FBgn0027316
FBgn0040175
FBgn0062480

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 89 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

33078

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VRD6

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VRD6

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0031145

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

33078/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0031145

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0031145

FlyMine - An integrated database for Drosophila genomics

FBgn0031145

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG1740

MARRVEL_MODEL - MARRVEL (model organism gene)

33078

Linkouts

BioGRID - A database of protein and genetic interactions.

59365

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0031145

DroID - A comprehensive database of gene and protein interactions.

FBgn0031145

DRSC - Results frm RNAi screens

FBgn0031145

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Ntf-2_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0031145

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0031145

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG1740

Flygut - An atlas of the Drosophila adult midgut

FBgn0031145

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC012876

MIST (protein-protein) - An integrated Molecular Interaction Database

33078

References (85)

The following external sites may use different assemblies or annotations than FlyBase.

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