FlyBase Gene Report: Dmel\Klp59C

General Information

Symbol

Dmel\Klp59C

Species

D. melanogaster

Name

Kinesin-like protein at 59C

Annotation Symbol

CG3219

Feature Type

protein_coding_gene

FlyBase ID

FBgn0034824

Gene Model Status

Current

Stock Availability

5 publicly available

Gene Summary

Required during anaphase to drive sister chromatid separation to actively depolymerize kinetochore microtubules at their kinetochore-associated plus ends, thereby contributing to chromatid mobility through a 'Pac-man' mechanism. (UniProt, Q9W1U4)

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
UniProtKB
Interactive Fly

Also Known As

DmKlp59C

Key Links

Genomic Location

Cytogenetic map

59C4-59C4

Sequence location

2R:23,123,923..23,126,042 [-]

Recombination map

2-102

RefSeq locus

NT_033778 REGION:23123923..23126042

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (12 terms)

Molecular Function (5 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables cytoskeletal motor activity

inferred from direct assay

(Rogers et al., 2004)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

enables ATP binding

inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821

(InterPro Project Members, 2004-)

enables ATP hydrolysis activity

inferred from biological aspect of ancestor with PANTHER:PTN000648413

(GO Reference Genome Project, 2011-)

enables microtubule binding

inferred from electronic annotation with InterPro:IPR001752

(InterPro Project Members, 2004-)

inferred from biological aspect of ancestor with PANTHER:PTN000648413

(GO Reference Genome Project, 2011-)

enables microtubule motor activity

inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821, InterPro:IPR027640

(InterPro Project Members, 2004-)

inferred from biological aspect of ancestor with PANTHER:PTN000648413

(GO Reference Genome Project, 2011-)

Biological Process (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

involved_in microtubule-based movement

inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821, InterPro:IPR027640

(InterPro Project Members, 2004-)

inferred from biological aspect of ancestor with PANTHER:PTN000648413

(GO Reference Genome Project, 2011-)

Cellular Component (6 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

located_in kinetochore microtubule

inferred from direct assay

(Rogers et al., 2004)

Terms Based on Predictions or Assertions (5 terms)

CV Term

Evidence

References

is_active_in centrosome

inferred from biological aspect of ancestor with PANTHER:PTN002380633

(GO Reference Genome Project, 2011-)

is_active_in cytoplasm

inferred from biological aspect of ancestor with PANTHER:PTN000648413

(GO Reference Genome Project, 2011-)

part_of kinesin complex

inferred from biological aspect of ancestor with PANTHER:PTN000648413

(GO Reference Genome Project, 2011-)

is_active_in microtubule

inferred from biological aspect of ancestor with PANTHER:PTN000648413

(GO Reference Genome Project, 2011-)

is_active_in spindle

inferred from biological aspect of ancestor with PANTHER:PTN000649352

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

KINESINS

Protein Family (UniProt)

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily. (Q9W1U4)

Protein Signatures (InterPro)

Catalytic Activity (EC/Rhea)

ATP hydrolysis activity
RHEA 13065:

Summaries

Gene Group (FlyBase)

KINESINS -: Kinesin superfamily proteins (KIFs) are microtubule motor proteins which use the hydrolysis of ATP to drive directional movement along microtubules. KIFs possess a well-conserved 360 residue globular head domain which binds and hydrolyses ATP and interacts with microtubules. Many KIFs homodimerize via coiled-coil interactions in the stalk region. KIFs bind cargo through their variable tail regions and are involved in transporting organelles, protein complexes, mRNAs and the movement of spindles and chromosomes during cell division. (Adapted from FBrf0219884).

Protein Function (UniProtKB)

(UniProt, Q9W1U4)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Klp59C for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9W1U4)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.52

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Klp59C-RA

FBtr0071975

NM_137915

2120

626

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Klp59C-PA

FBpp0071885

70.1

626

10.27

Q9W1U4

NP_611759

AAF46959

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q9W1U4

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Klp59C using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Klp59C_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

5.12

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in kinetochore microtubule

inferred from direct assay

(Rogers et al., 2004)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Klp59C in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Klp59C

View exonic expression by tissue for Dmel\Klp59C

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0034824

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

37671/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0034824

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0034824

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0034824

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG3219

Flygut - An atlas of the Drosophila adult midgut

FBgn0034824

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 0 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 6 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Klp59C

Transgenic constructs containing regulatory region of Klp59C

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(2R)Exel7177

(Ryder, 2004.4.26)

Inferred from location ( 4 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Klp59C^GD16138

viable, with Scer\GAL4^Mef2.PR

Klp59C^GD16138

viable, with Scer\GAL4^pnr-MD237

Klp59C^GD16138

viable, with Scer\GAL4^tin.CΔ4

Klp59C^GD16138

Other Phenotypes

Allele

abnormal neuroanatomy | P-stage, with Scer\GAL4^ppk.PU

Klp59C^GD16138

Phenotype manifest in

Allele

axon | larval stage, with Scer\GAL4^ppk.PU

Klp59C^GD16138

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (25)

Hsap\KIF2C

8 of 14

Yes

Hsap\KIF2A

7 of 14

Hsap\KIF2B

7 of 14

Hsap\KIF24

4 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (12)

Rnor\Kif2c

8 of 14

Yes

Rnor\Kif2b

7 of 14

Rnor\Kif2a

6 of 14

Rnor\Kif24

5 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Mus musculus (laboratory mouse) (13)

Mmus\Kif2c

8 of 14

Yes

Mmus\Kif2a

7 of 14

Mmus\Kif2b

7 of 14

Mmus\Kif24

4 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (14)

Xtro\kif2c

5 of 13

Yes

3 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\kif27

1 of 13

Xtro\man2b1

1 of 13

Xtro\nfic

1 of 13

Danio rerio (Zebrafish) (11)

Drer\kif2c

7 of 14

Yes

Drer\zgc:103670

7 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\si:dkey-26i13.8

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (8)

Cele\klp-7

9 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (13)

Agam\AgaP_AGAP000159

6 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (17)

Atha\AT3G16060

10 of 13

Yes

Atha\KINESIN-13A

9 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (1)

Scer\KIP3

1 of 13

Yes

Schizosaccharomyces pombe (Fission yeast) (2)

Spom\klp5

1 of 12

Yes

Spom\klp6

1 of 12

Yes

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Klp59C. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (26)

11 of 13

10 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

pav

3 of 13

sub

3 of 13

unc-104

3 of 13

cos

2 of 13

Khc

2 of 13

Kif3C

2 of 13

Klp3A

2 of 13

Klp61F

2 of 13

ncd

2 of 13

neb

2 of 13

nod

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

KIF2C; kinesin family member 2C

8 of 14

604538

KIF2A; kinesin family member 2A

7 of 14

602591

CORTICAL DYSPLASIA, COMPLEX, WITH OTHER BRAIN MALFORMATIONS 3; CDCBM3

complex cortical dysplasia with other brain malformations 3

KIF2B; kinesin family member 2B

7 of 14

615142

KIF24; kinesin family member 24

4 of 14

613747

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

63275

DroID - A comprehensive database of gene and protein interactions.

FBgn0034824

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Motor proteins

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-102

Cytogenetic map

59C4-59C4

Sequence location

2R:23,123,923..23,126,042 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

59C4-59C4

Limits computationally determined from genome sequence between P{PZ}l(2)06496⁰⁶⁴⁹⁶&P{lacW}l(2)k09913^k09913 and P{lacW}l(2)k07136^k07136

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-102

(FlyBase, 2016)

2-106.8

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (5)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

35596

y¹ sc^* v¹ sev²¹; P{TRiP.GL00433}attP2

64673

y¹ sc^* v¹ sev²¹; P{TRiP.HMC05708}attP40

NIG-Fly

2RG-1567

y² VhaAC39-1^cho-1 v¹; P{U6-Klp59C.NIG.sgRNA}attP40/CyO

VDRC

v109829

P{KK109925}VIE-260B

v48576

w¹¹¹⁸; P{GD16138}v48576

Genomic Clones (32)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (15)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0034824

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0034824

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

S2 cells treated with RNAi against Klp59C do not show a significant change in poleward flux rates of tubulin subunits in mitotic spindles and do not show a significant change in α-tubulin turnover at the microtubule plus or minus ends of the spindles when compared to control cells.

(Buster et al., 2007)

Klp59C is required to depolymerise kinetochore-associated plus ends, thereby contributing to chromatid motility through a 'pac-man'-based mechanism.

(Rogers et al., 2004)

The introduction of Klp59C inhibitors into embryos has no apparent effect on the organisation of mitotic spindles, but dies cause significant defects in chromomsome positioning and motility. Chromosomes and kinetochores fail to align tightly at the spindle equator during metaphase. Moreover normal chromosome segregation is prevented during anaphase.

(Rogers et al., 2004)

Relationship to Other Genes

Source for database merge of

Additional comments

The Klp59C gene may have been derived from the Klp10A gene by retroposition.

(Pan and Zhang, 2009)

Nomenclature History

Source for database identify of

Source for identity of: Klp59C CG3219

(Endow, 2001.4.14)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (11)

Reported As

Symbol Synonym

CG3219

(National Institute of Genetics Fly Stocks, 2022-, Ni et al., 2011.7.19, Keleman et al., 2009.8.5, Pan and Zhang, 2009, Perkins et al., 2009, Rogers, 2002.8.14, Miki et al., 2001)

DmCG3219

(Endow, 2001.4.14)

DmKLP59C

(Gadde and Heald, 2004)

DmKlp59C

(Hirokawa, 2012, Dagenbach and Endow, 2004, Endow, 2001.4.14, Kim and Endow, 2000)

KIF 2B

(Miki et al., 2001)

KIF2A/B/C

(Hirokawa, 2012.11.20)

KLP59C

(Schimizzi et al., 2010, Fernandez et al., 2009, Rath et al., 2009, Buster et al., 2007, Vendra et al., 2007, Civelekoglu-Scholey et al., 2006, Heun et al., 2006, Brittle and Ohkura, 2005, Mennella et al., 2005, Miki et al., 2005, Heald, 2004, Kwon and Scholey, 2004, Rogers et al., 2004, Sharp and Rogers, 2004, Rogers, 2002.8.14)

Klp59C

(Xu et al., 2025, Zheng et al., 2020, Tao et al., 2016, dos Santos, 2014, Hirokawa, 2012.11.20, Goodwin and Vale, 2010, Laycock et al., 2006)

Name Synonyms

Kinesin-like protein at 59C

(Hirokawa, 2012.11.20)

Kinesin13C

(Kollmar, 2015.9.15)

Klp59C

kinesin-13

(Fernandez et al., 2009)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 34 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

37671

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AI293978

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

AAF46959

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9W1U4

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q9W1U4

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9W1U4

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0034824

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

37671/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0034824

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0034824

FlyMine - An integrated database for Drosophila genomics

FBgn0034824

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG3219

MARRVEL_MODEL - MARRVEL (model organism gene)

37671

Linkouts

BioGRID - A database of protein and genetic interactions.

63275

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0034824

DroID - A comprehensive database of gene and protein interactions.

FBgn0034824

DRSC - Results frm RNAi screens

FBgn0034824

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Klp59C_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0034824

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0034824

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG3219

Flygut - An atlas of the Drosophila adult midgut

FBgn0034824

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0034824

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Motor proteins

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

References (59)

The following external sites may use different assemblies or annotations than FlyBase.

5.12

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