kinesin II, DmKlp68D, kinesin-2, KLP5
cytoskeletonal motor protein - Klp64D and Klp68D are kinesin-2α kinesin-2β motor subunits of the heterotrimeric kinesin-2 - Klp64D associates with Klp68D and Kap3 - Klp64D and Klp68D play an essential role in sensory cilia assembly and axonal transport - microtubule organization in dendrites - hearing
Gene model reviewed during 5.45
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Klp68D using the Feature Mapper tool.
Comment: reported as dorsal/lateral sensory complexes
GBrowse - Visual display of RNA-Seq signalsView Dmel\Klp68D in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Klp68D CG7293
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Molecular and biochemical properties of Klp68D suggest it may be used for anterograde axon transport and could move cargoes in neurons different to those moved by kinesin heavy chain or other plus-end directed motors.