funnel cakes, fun
Please see the JBrowse view of Dmel\Sec8 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.47
Low-frequency RNA-Seq exon junction(s) not annotated.
There is only one protein coding transcript and one polypeptide associated with this gene
The exocyst complex is composed of Sec3/Exoc1, Sec5/Exoc2, Sec6/Exoc3, Sec8/Exoc4, Sec10/Exoc5, Sec15/Exoc6, exo70/Exoc7 and Exo84/Exoc8.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Sec8 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Sec8 protein is localized to the growing end of the spermatid cyst
JBrowse - Visual display of RNA-Seq signals
View Dmel\Sec8 in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
sec8 is required for regulation of synaptic microtubule formation and regulation of synaptic growth and glutamate receptor trafficking.
Mutants are male sterile.
Source for merge of: sec8 CG2095
Source for merge of: sec8 fun
Source for merge of: Sec8 sec8
Source for identity of: Sec8 sec8
Named "Sec8" after the S. cerevisiae ortholog.