FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4klu-G410
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General Information
Symbol
Scer\GAL4klu-G410
Species
S. cerevisiae
Name
FlyBase ID
FBal0065091
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Klu-Gal4, klumpfuss-GAL4
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description
Allele components
Component
Use(s)
Inserted element
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Drives expression in a subset of embryonic neuroblasts, in the posterior spiracle primordium, and in larval proneural clusters. Also drives expression in a complex pattern in imaginal discs.

ScerGAL4klu-G410 drives expression in the developing leg joints in the leg disc at larval and pupal stages, and in adult leg joints.

ScerGAL4klu-G410 drives strong expression in neuroblasts of the procephalon and trunk from stage 9 onwards. Expression is observed in a complex and dynamic pattern throughout much of larval and imaginal development. The imaginal disc pattern is described in detail for klu transcript, and authors state reporter expression has the same pattern. Early in third instar larvae, expression is observed in the prospective wing area of the wing disc. Shortly thereafter, it is restricted to the prospective margin and hinge of the wing. About the same time, expression is observed in the anlagen of the notum and scutellum. Expression is observed in most proneural clusters at or shortly after the time of ac expression. klu expression in these regions precedes the appearance of SOPs and is not continued in the SOPs themselves. Expression in leg discs also starts early in the third instar. The klu expression domain occupies a wedge-like sector encompassing about 1/3 of the circumferenceof the leg disc. Expression is in rings corresponding to the anlagen of the leg segments. Expression in the antennal and dorsal prothoracic discs also occurs in concentric domains. In eye discs, expression starts behind the morphogenetic furrow and extends through the whole anlage. Expression in the larval brain is restricted to the neuroblasts and the proliferation zone of the optic lobes.

 
Marker for
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

femur & joint, with DeltaUAS.cDa

leg & joint, with NECN.UAS

mesothoracic tergum & microchaeta, with Hsap\EZR1-280.UAS.GFP

tarsal segment & joint, with DeltaUAS.cDa

tibia & joint, with DeltaUAS.cDa

Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
GAL4klu-G410
Scer\GAL4klu-G410
Name Synonyms
Secondary FlyBase IDs
    References (25)