FlyBase Allele Report: Dmel\Nab2[EP3716]

General Information

Symbol

Dmel\Nab2^EP3716

Species

D. melanogaster

Name

FlyBase ID

FBal0119703

Feature type

allele

Associated gene

Dmel\Nab2

Associated Insertion(s)

P{EP}Nab2^EP3716

Carried in Construct

Also Known As

dNab2^EP3716

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Bidet et al., 2003, Pena-Rangel et al., 2002, Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000)

Progenitor genotype

Associated Insertion(s)

P{EP}Nab2^EP3716

Cytology

Description

P{EP} insertion upstream of CG5720.

(Bidet et al., 2003)

P{EP} insertion at +34bp of EST BEST:GH27517 .

(Abdelilah-Seyfried et al., 2000)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:24,318,359..24,318,359 [-]

(Corgiat et al., 2022, Rounds et al., 2022, Corgiat et al., 2021, Lee et al., 2020, Bienkowski et al., 2017, Bidet et al., 2003, Pena-Rangel et al., 2002, Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of autosomal recessive intellectual developmental disorder

CEA

(Rounds et al., 2022, Bienkowski et al., 2017)

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

model of autosomal recessive intellectual developmental disorder

is ameliorated by Fmr1^Δ113M

(Bienkowski et al., 2017)

is ameliorated by Fmr1^Δ50M

(Bienkowski et al., 2017)

is ameliorated by Fmr1^GL00075

(Bienkowski et al., 2017)

is ameliorated by Pabp2^EP2264

(Bienkowski et al., 2017)

is exacerbated by drk^e0A

(Rounds et al., 2022)

is ameliorated by mtd⁴

(Rounds et al., 2022)

is ameliorated by Bsg^k13638

(Rounds et al., 2022)

is ameliorated by Gαo^KO

(Rounds et al., 2022)

is ameliorated by HmgZ^KG01188

(Rounds et al., 2022)

is ameliorated by sm¹

(Rounds et al., 2022)

is ameliorated by stai^KO

(Rounds et al., 2022)

is ameliorated by Arpc2^KG04658

(Rounds et al., 2022)

is ameliorated by Atx2^DG08112

(Rounds et al., 2022)

is ameliorated by Atx2^X1

(Rounds et al., 2022)

exacerbates fragile X syndrome

modeled by Fmr1^UAS.cWa

(Bienkowski et al., 2017)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eye color, with Scer\GAL4^GMR.PU

(Rounds et al., 2022, Bienkowski et al., 2017)

abnormal eye color | adult stage, with Scer\GAL4^GMR.PU

(Lee et al., 2020)

abnormal size | adult stage, with Scer\GAL4^GMR.PU

(Bienkowski et al., 2017)

decreased size | adult stage, with Scer\GAL4^GMR.PU

(Lee et al., 2020)

visible, with Scer\GAL4^GMR.PF

(Müller et al., 2005)

visible, with Scer\GAL4^GMR.PU

(Pak et al., 2011)

visible, with Scer\GAL4^ptc-559.1

(Abdelilah-Seyfried et al., 2000)

visible | adult stage, with Scer\GAL4^GMR.PU

(Rounds et al., 2022, Lee et al., 2020, Bienkowski et al., 2017)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PF

(Müller et al., 2005)

eye, with Scer\GAL4^GMR.PU

(Rounds et al., 2022, Lee et al., 2020, Bienkowski et al., 2017, Pak et al., 2011)

ommatidium, with Scer\GAL4^GMR.PU

(Rounds et al., 2022)

ommatidium | adult stage, with Scer\GAL4^GMR.PU

(Bienkowski et al., 2017)

scutellar bristle, with Scer\GAL4^ptc-559.1

(Abdelilah-Seyfried et al., 2000)

Detailed Description

Statement

Reference

The expression of Nab2^EP3716 under the control of Scer\GAL4^GMR.PU results in eye defects, including posterior pigment loss, sporadic blackened patches, and ommatidial disordering or "roughness".

(Rounds et al., 2022)

Expression of Nab2^EP3716 under the control of Scer\GAL4^GMR.PU results in eyes of reduced size that lack full pigmentation and have disorganized ommatidia.

(Bienkowski et al., 2017)

Expression of Nab2^EP3716 under the control of Scer\GAL4^GMR.PU results in a rough eye phenotype.

(Pak et al., 2011)

Expression of CG5720^EP3716 under the control of Scer\GAL4^GMR.PF results in a big eye phenotype.

(Müller et al., 2005)

Expression of CG5720^EP3716 under the control of Scer\GAL4^ptc-559.1 results in the loss of several scutellar macrochaetae.

(Abdelilah-Seyfried et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by drk[+]/drk^e0A

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal eye color phenotype, enhanceable by drk[+]/drk^e0A

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, enhanceable by Vang^stbm-6/Vang[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by Vang^stbm-6/Vang[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by Pabp2[+]/Pabp2⁵⁵

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, enhanceable by Pabp2[+]/Pabp2⁵⁵

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by hrg¹⁰/hrg[+]

(Pak et al., 2011)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Pabp2[+]/Pabp2⁵⁵

(Pak et al., 2011)

NOT Enhanced by

Statement

Reference

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, non-enhanceable by me31B^k06607/me31B[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal eye color phenotype, non-enhanceable by me31B^k06607/me31B[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, non-enhanceable by dsh[+]/dsh⁶

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, non-enhanceable by dsh[+]/dsh⁶

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, non-enhanceable by Vang^stbm-153/Vang[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, non-enhanceable by Vang^stbm-153/Vang[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, non-enhanceable by pk[+]/pk^pk-sple-13

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, non-enhanceable by pk[+]/pk^pk-sple-13

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^sca-537.4 has visible phenotype, non-enhanceable by N[+]/N^55e11

(Abdelilah-Seyfried et al., 2000)

Suppressed by

Statement

Reference

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal eye color phenotype, suppressible by mtd[+]/mtd⁴

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal eye color phenotype, suppressible | partially by Galphao[+]/Gαo^KO

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal eye color phenotype, suppressible | partially by Df(3L)Exel6137/+

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by Atx2^X1/Atx2[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal eye color phenotype, suppressible by Atx2^X1/Atx2[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by Atx2^DG08112/Atx2[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal eye color phenotype, suppressible by Atx2^DG08112/Atx2[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by Arpc2^KG04658/Arpc2[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by Bsg^k13638/Bsg[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by Galphao[+]/Gαo^KO

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by HmgZ[+]/HmgZ^KG01188

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by sm[+]/sm¹

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by stai[+]/stai^KO

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by mtd[+]/mtd⁴

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by Df(3L)Exel6137/+

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal eye color phenotype, suppressible by Arpc2^KG04658/Arpc2[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal eye color phenotype, suppressible by Bsg^k13638/Bsg[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal eye color phenotype, suppressible by HmgZ[+]/HmgZ^KG01188

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal eye color phenotype, suppressible by stai[+]/stai^KO

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal eye color phenotype, suppressible by sm[+]/sm¹

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by dsh³/dsh[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, suppressible | partially by dsh³/dsh[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, suppressible | partially by fz[+]/fz¹

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by fz[+]/fz¹

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by fz^JB/fz[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, suppressible | partially by fz^JB/fz[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, suppressible | partially by stan[+]/stan^frz3

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by stan[+]/stan^frz3

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, suppressible | partially by pk[+]/pk^pk-sple-14

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by pk[+]/pk^pk-sple-14

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, suppressible by DAAM[+]/DAAM^A

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible by DAAM[+]/DAAM^A

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, suppressible | partially by DAAM[+]/DAAM^G1567

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by DAAM[+]/DAAM^G1567

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by Appl^d/Appl[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, suppressible by Wnt4[+]/Wnt4^EMS23

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible by Wnt4[+]/Wnt4^EMS23

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, suppressible | partially by Wnt4^C1/Wnt4[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, suppressible | partially by tap^MI10541/tap[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by tap^MI10541/tap[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, suppressible | partially by puc^MI11060/puc[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by puc^MI11060/puc[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, suppressible | partially by Rbsn-5^X17/Rbsn-5[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by Df(2R)pk³⁰/+

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by Wnt4^C1/Wnt4[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by Rbsn-5^X17/Rbsn-5[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, suppressible | partially by stan[+]/stan^E59

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible by Fmr1^Δ50M/Fmr1[+]

(Bienkowski et al., 2017)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal eye color phenotype, suppressible by Fmr1^Δ50M/Fmr1[+]

(Bienkowski et al., 2017)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal size | adult stage phenotype, suppressible by Fmr1^Δ50M/Fmr1[+]

(Bienkowski et al., 2017)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible by Fmr1^Δ113M/Fmr1[+]

(Bienkowski et al., 2017)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal eye color phenotype, suppressible by Fmr1^Δ113M/Fmr1[+]

(Bienkowski et al., 2017)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal size | adult stage phenotype, suppressible by Fmr1^Δ113M/Fmr1[+]

(Bienkowski et al., 2017)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible by Fmr1^GL00075, Scer\GAL4^GMR.PU

(Bienkowski et al., 2017)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal eye color phenotype, suppressible by Fmr1^GL00075, Scer\GAL4^GMR.PU

(Bienkowski et al., 2017)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal size | adult stage phenotype, suppressible by Fmr1^GL00075, Scer\GAL4^GMR.PU

(Bienkowski et al., 2017)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Pabp2^EP2264, Scer\GAL4^GMR.PU

(Pak et al., 2011)

NOT suppressed by

Statement

Reference

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, non-suppressible by me31B^k06607/me31B[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has abnormal eye color phenotype, non-suppressible by me31B^k06607/me31B[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, non-suppressible by dsh[+]/dsh⁶

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, non-suppressible by dsh[+]/dsh⁶

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, non-suppressible by Vang^stbm-153/Vang[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, non-suppressible by Vang^stbm-153/Vang[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has visible | adult stage phenotype, non-suppressible by pk[+]/pk^pk-sple-13

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, non-suppressible by pk[+]/pk^pk-sple-13

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^sca-537.4 has visible phenotype, non-suppressible by N[+]/N^55e11

(Abdelilah-Seyfried et al., 2000)

Enhancer of

Statement

Reference

Nab2^EP3716, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of H^UAS.cMa, Scer\GAL4^GMR.PF

(Müller et al., 2005)

Nab2^EP3716/Scer\GAL4^pnr-MD237 is an enhancer of visible phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

Other

Statement

Reference

Nab2^EP3716, Pabp2⁵⁵, Scer\GAL4^GMR.PU has partially lethal phenotype

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+] has abnormal planar polarity phenotype

(Pena-Rangel et al., 2002)

Nab2^EP3716, Scer\GAL4^pnr-MD237, pnr^MD237 has abnormal planar polarity phenotype

(Pena-Rangel et al., 2002)

Phenotype Manifest In

Enhanced by

Statement

Reference

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by drk[+]/drk^e0A

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Vang^stbm-6/Vang[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Pabp2[+]/Pabp2⁵⁵

(Lee et al., 2020, Pak et al., 2011)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by hrg¹⁰/hrg[+]

(Pak et al., 2011)

NOT Enhanced by

Statement

Reference

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by me31B^k06607/me31B[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by dsh[+]/dsh⁶

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by Vang^stbm-153/Vang[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by pk[+]/pk^pk-sple-13

(Lee et al., 2020)

Suppressed by

Statement

Reference

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by Atx2^X1/Atx2[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by Atx2^DG08112/Atx2[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by Bsg^k13638/Bsg[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by sm[+]/sm¹

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by Galphao[+]/Gαo^KO

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by HmgZ[+]/HmgZ^KG01188

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by Arpc2^KG04658/Arpc2[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by Df(3L)Exel6137/+

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by stai[+]/stai^KO

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by mtd[+]/mtd⁴

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by dsh³/dsh[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by fz[+]/fz¹

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by fz^JB/fz[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by stan[+]/stan^frz3

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by pk[+]/pk^pk-sple-14

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible by DAAM[+]/DAAM^A

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by DAAM[+]/DAAM^G1567

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by Appl^d/Appl[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Wnt4[+]/Wnt4^EMS23

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by Wnt4^C1/Wnt4[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by tap^MI10541/tap[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by puc^MI11060/puc[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by Rbsn-5^X17/Rbsn-5[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by Df(2R)pk³⁰/+

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Fmr1^Δ50M/Fmr1[+]

(Bienkowski et al., 2017)

Nab2^EP3716, Scer\GAL4^GMR.PU has ommatidium | adult stage phenotype, suppressible by Fmr1^Δ50M/Fmr1[+]

(Bienkowski et al., 2017)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Fmr1^Δ113M/Fmr1[+]

(Bienkowski et al., 2017)

Nab2^EP3716, Scer\GAL4^GMR.PU has ommatidium | adult stage phenotype, suppressible by Fmr1^Δ113M/Fmr1[+]

(Bienkowski et al., 2017)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Fmr1^GL00075, Scer\GAL4^GMR.PU

(Bienkowski et al., 2017)

Nab2^EP3716, Scer\GAL4^GMR.PU has ommatidium | adult stage phenotype, suppressible by Fmr1^GL00075, Scer\GAL4^GMR.PU

(Bienkowski et al., 2017)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Pabp2^EP2264, Scer\GAL4^GMR.PU

(Pak et al., 2011)

NOT suppressed by

Statement

Reference

Nab2^EP3716, Scer\GAL4^GMR.PU has ommatidium phenotype, non-suppressible by Atx2^X1/Atx2[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has ommatidium phenotype, non-suppressible by Atx2^DG08112/Atx2[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by me31B^k06607/me31B[+]

(Rounds et al., 2022)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by dsh[+]/dsh⁶

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by Vang^stbm-153/Vang[+]

(Lee et al., 2020)

Nab2^EP3716, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by pk[+]/pk^pk-sple-13

(Lee et al., 2020)

Enhancer of

Statement

Reference

Nab2^EP3716, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of H^UAS.cMa, Scer\GAL4^GMR.PF

(Müller et al., 2005)

Nab2^EP3716/Scer\GAL4^pnr-MD237 is an enhancer of chaeta phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

NOT Enhancer of

Statement

Reference

Nab2^EP3716/Scer\GAL4^sca-537.4 is a non-enhancer of phenotype of N^55e11

(Abdelilah-Seyfried et al., 2000)

Other

Statement

Reference

Nab2^EP3716, Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+] has scutellum phenotype

(Pena-Rangel et al., 2002)

Nab2^EP3716, Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+] has microchaeta phenotype

(Pena-Rangel et al., 2002)

Nab2^EP3716, Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+] has adult thorax phenotype

(Pena-Rangel et al., 2002)

Nab2^EP3716, Scer\GAL4^pnr-MD237, pnr^MD237 has scutellum phenotype

(Pena-Rangel et al., 2002)

Nab2^EP3716, Scer\GAL4^pnr-MD237, pnr^MD237 has microchaeta phenotype

(Pena-Rangel et al., 2002)

Nab2^EP3716, Scer\GAL4^pnr-MD237, pnr^MD237 has adult thorax phenotype

(Pena-Rangel et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

The eye defects (reduced size, partial depigmentation and disorganization of the ommatidial lattice) characteristic for adult flies expressing Nab2^EP3716 under the control of Scer\GAL4^GMR.PU can be suppressed by combination with a single copy of either Fmr1^Δ50M or Fmr1^Δ113M or by co-expression of Fmr1^GL00075.

(Bienkowski et al., 2017)

hrg¹⁰/+ strongly enhances the mutant eye phenotype caused by expression of Nab2^EP3716 under the control of Scer\GAL4^GMR.PU.

Pabp2⁵⁵/+ strongly enhances the mutant eye phenotype caused by expression of Nab2^EP3716 under the control of Scer\GAL4^GMR.PU, resulting in a smaller, more disorganised and blackened eye.

Co-expression of Pabp2^EP2264 significantly suppresses the rough eye phenotype caused by expression of Nab2^EP3716 under the control of Scer\GAL4^GMR.PU.

(Pak et al., 2011)

pnr^MD237/+ adults expressing CG5720^EP3716 under the control of Scer\GAL4^pnr-MD237 have short microchaetae without polarity, a deformed scutellum and overpigmentation in the thoracic dorsal midline.

(Pena-Rangel et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

17159

w¹¹¹⁸; P{EP}Nab2^EP3716/TM6B, Tb¹

Notes on Origin

Discoverer

Selected as: a P{EP} insertion line that modifies the pnr^MD237/+ phenotype when expressed using Scer\GAL4^pnr-MD237.

(Pena-Rangel et al., 2002)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

BEST:GH27517^EP3716

BcDNA:LD27873^EP3716

(Pena-Rangel et al., 2002)

CG5720^EP3716

EP(3)3716

(Abdelilah-Seyfried et al., 2000)

Nab2^EP3716

(Corgiat et al., 2022, Rounds et al., 2022, Corgiat et al., 2021, Lee et al., 2020)

dNab2^EP3716

(Bienkowski et al., 2017, Pak et al., 2011)

Name Synonyms

Secondary FlyBase IDs

References (11)

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