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FB2026_01
,
released March 12, 2026
Ser99Db, Jon99Cβiii, SP143, Jon99C, Ser2
Please see the JBrowse view of Dmel\Jon99Ciii for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.53
Gene model reviewed during 5.44
Apparent introns not annotated: probable artifacts due to repetitive sequence.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.56
The group(s) of polypeptides indicated below share identical sequence to each other.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Jon99Ciii using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\Jon99Ciii in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
D.melanogaster is polymorphic for the number of "Jonah" genes in 99C. In the "β" arrangement, 4 copies are present; Jon99Co, Jon99Ci, Jon99Cii and Jon99Ciii, with Jon99Ci and Jon99Cii representing a tandem duplication of an approximately 1.8kb fragment. In the "α" arrangement, this 1.8kb fragment is only present in one copy ("Jon99Cαi").
Source for merge of: Jon99Ciii Ser99Db
Characterization of LAP genes "Lap-A" and "Lap-D" from the distribution and enzymatic activity of their proteins reveals a striking resemblance to the description of Jonah genes in 99C ("Jon99Co", "Jon99Ci", "Jon99Cii" and "Jon99Ciii") and 99F ("Jon99Fi" and "Jon99Fii") and the pattern of expression of their transcripts. At least one of the Jonah genes in 99C or 99F may correspond to "Lap-A" or "Lap-D".
One of a number of genes isolated from a cDNA library made from third instar salivary glands, but subsequently found not to be expressed in the salivary glands but instead expressed specifically and abundantly in the midgut (which resulted in contamination of the original cDNA library). This surprising discovery prompted the name "Jonah" for this family of genes, after the Biblical prophet who unexpectedly turned up in the gut.
