FlyBase Gene Report: Dmel\RhoGAP19D

General Information

Symbol

Dmel\RhoGAP19D

Species

D. melanogaster

Name

Rho GTPase activating protein at 19D

Annotation Symbol

CG1412

Feature Type

protein_coding_gene

FlyBase ID

FBgn0031118

Gene Model Status

Current

Stock Availability

12 publicly available

Gene Summary

the only high-probability Cdc42GAP required for polarity in the follicular epithelium - recruited by α-catenin to lateral E-cadherin adhesion complexes, resulting in exclusion of active Cdc42 from the lateral domain - couples lateral cadherin adhesion to the apical localization of active Cdc42, thereby suppressing epithelial invasion - controls Rac and Rho GTPases during the dorsal closure and genetically regulates the elmo-mbc complex - RhoGAP19D-depleted embryos displayed complex epidermal cell phenotypes (a fragmented actomyosin cable, bimodal leading-edge tensions, transient Rac and lamellipodia states, and cadherin height defects) (Interactive Fly, RhoGAP19D )

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

19D1-19D2

Sequence location

X:20,469,955..20,510,694 [-]

Recombination map

1-64

RefSeq locus

NC_004354 REGION:20469955..20510694

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (7 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables GTPase activator activity

inferred from biological aspect of ancestor with PANTHER:PTN000571279

(GO Reference Genome Project, 2011-)

inferred from sequence or structural similarity with SGD:S000000957

(Gene Ontology Curators, 2002-)

Biological Process (4 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in imaginal disc-derived leg morphogenesis

inferred from mutant phenotype

(Greenberg and Hatini, 2011)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in Rho protein signal transduction

inferred from sequence or structural similarity with SGD:S000000957

(Gene Ontology Curators, 2002-)

involved_in signal transduction

inferred from electronic annotation with InterPro:IPR000198

(InterPro Project Members, 2004-)

involved_in small GTPase-mediated signal transduction

inferred from biological aspect of ancestor with PANTHER:PTN000571279

(GO Reference Genome Project, 2011-)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

is_active_in cytoplasm

inferred from biological aspect of ancestor with PANTHER:PTN000571279

(GO Reference Genome Project, 2011-)

is_active_in plasma membrane

inferred from biological aspect of ancestor with PANTHER:PTN000571279

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

RHO GTPASE ACTIVATING PROTEINS

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

RHO GTPASE ACTIVATING PROTEINS -: RhoGAPs are GTPase activating proteins for Rho family GTPases. (Adapted from PMID:15731001 and FBrf0158741).

Summary (Interactive Fly)

Interactive Fly

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\RhoGAP19D for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry X2JEI9)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.50

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.55

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

RhoGAP19D-RA

FBtr0077320

NM_134552

7735

2181

RhoGAP19D-RB

FBtr0301537

NM_001169338

9211

2109

RhoGAP19D-RC

FBtr0304906

NM_001258851

9289

2135

RhoGAP19D-RD

FBtr0340405

NM_001298567

9502

2206

RhoGAP19D-RE

FBtr0345015

NM_001298568

8804

2135

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

RhoGAP19D-PA

FBpp0077012

229.8

2181

9.31

FBpp0290752

222.3

2109

9.22

FBpp0293445

224.9

2135

9.16

FBpp0309351

232.3

2206

9.26

FBpp0311266

224.9

2135

9.16

M9NFH4

NP_001285497

AHN59967

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

2135 aa isoforms: RhoGAP19D-PC, RhoGAP19D-PE

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\RhoGAP19D using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-1.33

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism | ubiquitous

• cytoplasm | basal

Comment: apically cleared

(Fisher et al., 2012)

embryonic stage 7 -- 8

trunk mesoderm

(Fisher et al., 2012)

embryonic stage 9 -- 10

trunk mesoderm

(Fisher et al., 2012)

embryonic stage 11 -- 12

fat body/gonad primordium

(Fisher et al., 2012)

longitudinal trunk visceral muscle primordium

(Fisher et al., 2012)

organism | faint | ubiquitous

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic/larval posterior spiracle

(Fisher et al., 2012)

longitudinal intestinal visceral muscle fiber

(Fisher et al., 2012)

organism | faint | ubiquitous

(Fisher et al., 2012)

prepupal stage P3

leg | ubiquitous

(Greenberg and Hatini, 2011)

Additional Descriptive Data

Expression in stage P3 pupal leg discs is ubiquitous.

(Greenberg and Hatini, 2011)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\RhoGAP19D in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\RhoGAP19D

View exonic expression by tissue for Dmel\RhoGAP19D

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0031118

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

33048/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0031118

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0031118

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0031118

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG1412

Flygut - An atlas of the Drosophila adult midgut

FBgn0031118

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\RhoGAP19D

Stages(s) 1-3
Stages(s) 4-6
Stages(s) 7-8
Stages(s) 11-12
Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 17 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 5 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of RhoGAP19D

Transgenic constructs containing regulatory region of RhoGAP19D

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 14 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

partially lethal

RhoGAP19D^unspecified

partially lethal, with Scer\GAL4^tin.CΔ4

RhoGAP19D^GD5226

partially lethal - majority die, with Scer\GAL4^pnr-MD237

RhoGAP19D^GD5226

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

RhoGAP19D^GD5226

Other Phenotypes

Allele

abnormal cell shape

RhoGAP19D^unspecified

visible, with Scer\GAL4^pnr-MD237

RhoGAP19D^GD5226

Phenotype manifest in

Allele

egg chamber

RhoGAP19D^unspecified

epithelium | embryonic stage | maternal effect

RhoGAP19D^unspecified

follicle cell | somatic clone

RhoGAP19D^unspecified

male accessory gland

RhoGAP19D^unspecified

trichogen cell, with Scer\GAL4^pnr-MD237

RhoGAP19D^GD5226

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (54)

Hsap\ARHGAP23

9 of 14

Yes

Hsap\ARHGAP21

8 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (41)

Rnor\Arhgap23

9 of 14

Yes

Rnor\Arhgap21

8 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (39)

Mmus\Arhgap23

9 of 14

Yes

Mmus\Arhgap21

8 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (33)

Xtro\arhgap21

5 of 13

Yes

Xtro\arhgap23

3 of 13

Yes

2 of 13

2 of 13

1 of 13

1 of 13

Yes

Xtro\arhgap5

1 of 13

Xtro\arhgap10

1 of 13

Xtro\arhgap11a.1

1 of 13

Yes

Xtro\arhgap11a.2

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\syde2

1 of 13

Xtro\tagap

1 of 13

Danio rerio (Zebrafish) (54)

Drer\arhgap23a

9 of 14

Yes

Drer\arhgap21b

8 of 14

Yes

Drer\arhgap23b

8 of 14

Yes

Drer\arhgap21a

7 of 14

Yes

Drer\arhgap12a

2 of 14

Drer\arhgap12b

2 of 14

Drer\arhgap15

2 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Drer\si:ch1073-416j23.1

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (11)

Cele\pac-1

6 of 14

Yes

2 of 14

2 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (13)

Agam\AgaP_AGAP000504

8 of 12

Yes

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (1)

Atha\AT5G19390

1 of 13

Yes

Saccharomyces cerevisiae (Brewer's yeast) (6)

Scer\BEM2

3 of 13

Yes

Scer\RGA1

3 of 13

Yes

Scer\RGD1

3 of 13

Yes

Scer\RGA2

2 of 13

Scer\BEM3

1 of 13

Scer\LRG1

1 of 13

Schizosaccharomyces pombe (Fission yeast) (3)

Spom\rga7

4 of 12

Yes

Spom\rga3

2 of 12

Spom\rga4

1 of 12

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:RhoGAP19D. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (12)

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

tum

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

ARHGAP23; Rho GTPase activating protein 23

9 of 14

610590

ARHGAP21; Rho GTPase activating protein 21

8 of 14

609870

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

suppressible

(Fic et al., 2021)

suppressible

(Fic et al., 2021)

enhanceable

(Fic et al., 2021)

suppressible

(Fic et al., 2021)

enhanceable

(Fic et al., 2021)

enhanceable

(Fic et al., 2021)

enhanceable

(Fic et al., 2021)

suppressible

(Fic et al., 2021)

enhanceable

(Fic et al., 2021)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

59337

DroID - A comprehensive database of gene and protein interactions.

FBgn0031118

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

E1JJS2

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

1-64

Cytogenetic map

19D1-19D2

Sequence location

X:20,469,955..20,510,694 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

19D1-19D2

Limits computationally determined from genome sequence between P{EP}CG1702^EP1525 and P{EP}EP1465&P{EP}CG1486^EP1192

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

1-64

(FlyBase, 2016)

1-64.6

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (12)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

66167

w^*; P{UASp-GFP.RhoGAP19D}attP2

85202

w¹¹¹⁸ PBac{WH}RhoGAP19D^f02168

6435

y¹ w^*; P{UAS-RhoGAP19D.RNAi.B}2.1

6436

y¹ w^*; P{UAS-RhoGAP19D.RNAi.B}3.1

51150

y¹ w^* Mi{MIC}RhoGAP19D^MI07163

78314

y¹ w^* Mi{PT-GFSTF.0}RhoGAP19D^{MI07163-GFSTF.0}

76687

y¹ Mi{Trojan-GAL4.0}RhoGAP19D^{MI07163-TG4.0} w^*

10856

10870

104221

y^* w^* P{GawB}RhoGAP19D^NP2497 / FM7c

VDRC

v330193

P{VSH330193}attP40

v43955

w¹¹¹⁸ P{GD5226}v43955

Genomic Clones (24)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (42)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

MIP09872

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0031118

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0031118

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R⁺ cell morphology.

(Kiger et al., 2003)

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Name Synonyms

Rho GTPase activating protein at 19D

RhoGAP19D

(Trivedi et al., 2022)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 67 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

33048

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

X2JEI9

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

X2JEI9

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0031118

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

33048/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0031118

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0031118

FlyMine - An integrated database for Drosophila genomics

FBgn0031118

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG1412

MARRVEL_MODEL - MARRVEL (model organism gene)

33048

Linkouts

BioGRID - A database of protein and genetic interactions.

59337

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0031118

DroID - A comprehensive database of gene and protein interactions.

FBgn0031118

DRSC - Results frm RNAi screens

FBgn0031118

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0031118

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0031118

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG1412

Flygut - An atlas of the Drosophila adult midgut

FBgn0031118

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0031118

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC034405

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

E1JJS2

References (56)

The following external sites may use different assemblies or annotations than FlyBase.

-1.33

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