FlyBase Gene Report: Dmel\syd

General Information

Symbol

Dmel\syd

Species

D. melanogaster

Name

sunday driver

Annotation Symbol

CG8110

Feature Type

protein_coding_gene

FlyBase ID

FBgn0024187

Gene Model Status

Current

Stock Availability

9 publicly available

Gene Summary

sunday driver (syd) encodes a member of a family of scaffolding proteins that bind to JNK and facilitate its activation. syd is an organ size regulator that functions in Hippo signaling and is essential for Diap1 protein stability and function. [Date last reviewed: 2021-02-04] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
UniProtKB
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

66A20-66A20

Sequence location

3L:7,916,650..7,936,120 [-]

Recombination map

3-21

RefSeq locus

NT_037436 REGION:7916650..7936120

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (15 terms)

Molecular Function (4 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

enables kinesin binding

inferred from physical interaction with FLYBASE:Klc; FB:FBgn0010235

(Bowman et al., 2000)

enables signaling receptor complex adaptor activity

inferred from physical interaction with FLYBASE:side-IV; FB:FBgn0038156

(Osaka et al., 2024)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

enables JUN kinase binding

inferred from biological aspect of ancestor with PANTHER:PTN000356517

(GO Reference Genome Project, 2011-)

enables kinesin binding

inferred from biological aspect of ancestor with PANTHER:PTN001015989

(GO Reference Genome Project, 2011-)

enables MAP-kinase scaffold activity

inferred from sequence or structural similarity with UniProtKB:Q9ESN9

(Gene Ontology Curators, 2002-)

inferred from electronic annotation with InterPro:IPR039911

(InterPro Project Members, 2004-)

inferred from biological aspect of ancestor with PANTHER:PTN001015989

(GO Reference Genome Project, 2011-)

enables signaling receptor complex adaptor activity

inferred from biological aspect of ancestor with PANTHER:PTN001015989

(GO Reference Genome Project, 2011-)

Biological Process (6 terms)

Terms Based on Experimental Evidence (5 terms)

CV Term

Evidence

References

involved_in axo-dendritic transport

inferred from mutant phenotype

(Bowman et al., 2000)

involved_in negative regulation of apoptotic process

inferred from mutant phenotype

(Ahmad et al., 2021)

involved_in protein stabilization

inferred from mutant phenotype

(Ahmad et al., 2021)

involved_in synapse assembly

inferred from genetic interaction with FLYBASE:side-IV; FB:FBgn0038156

(Osaka et al., 2024)

involved_in vesicle-mediated transport

inferred from expression pattern

(Bowman et al., 2000)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in regulation of JNK cascade

inferred from sequence or structural similarity with UniProtKB:Q9ESN9

(Gene Ontology Curators, 2002-)

involved_in vesicle-mediated transport

inferred from biological aspect of ancestor with PANTHER:PTN001015989

(GO Reference Genome Project, 2011-)

Cellular Component (5 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

is_active_in presynaptic cytosol

inferred from direct assay

(Osaka et al., 2024)

located_in trans-Golgi network transport vesicle

inferred from direct assay

(Bowman et al., 2000)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

is_active_in cytoplasm

inferred from biological aspect of ancestor with PANTHER:PTN001015989

(GO Reference Genome Project, 2011-)

located_in Golgi membrane

inferred from sequence or structural similarity with UniProtKB:Q9ESN9

(Gene Ontology Curators, 2002-)

located_in membrane

inferred from sequence or structural similarity with UniProtKB:O60271

(Bowman et al., 2000)

inferred from sequence or structural similarity with UniProtKB:Q9UPT6

(Bowman et al., 2000)

Gene Group (FlyBase)

Protein Family (UniProt)

Belongs to the JIP scaffold family. (Q9GQF1)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Protein Function (UniProtKB)

The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK-signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins. Syd is required for efficient kinesin-I mediated axonal transport.

(UniProt, Q9GQF1)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\syd for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9GQF1)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Alternative translation stop created by use of multiphasic reading frames within coding region.

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Gene model reviewed during 5.45

Gene model reviewed during 5.56

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

syd-RA

FBtr0076768

NM_079913

4467

1227

syd-RB

FBtr0076769

NM_168245

4459

1194

syd-RC

FBtr0300412

NM_001169902

5095

1215

syd-RD

FBtr0300413

NM_001169903

4441

1188

syd-RE

FBtr0332787

NM_001274619

5056

1202

syd-RF

FBtr0332788

NM_001274620

4995

1214

syd-RG

FBtr0332789

NM_001274621

5148

1205

syd-RH

FBtr0332790

NM_001274622

5074

1208

syd-RI

FBtr0332791

NM_001274623

5013

1220

syd-RJ

FBtr0332792

NM_001274624

5166

1211

syd-RK

FBtr0345912

NM_001300046

5252

1214

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

syd-PA

FBpp0076483

136.7

1227

5.15

FBpp0076484

133.2

1194

5.37

NP_729311

AAN12032

syd-PC

FBpp0289641

135.3

1215

5.29

FBpp0289642

132.5

1188

5.42

FBpp0305014

133.8

1202

5.37

FBpp0305015

135.2

1214

5.21

FBpp0305016

134.1

1205

5.33

FBpp0305017

134.5

1208

5.33

FBpp0305018

135.9

1220

5.18

FBpp0305019

134.8

1211

5.29

FBpp0311832

135.2

1214

5.21

M9PEX9

NP_001286975

AHN58000

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1214 aa isoforms: syd-PF, syd-PK

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Subunit Structure (UniProtKB)

Forms homo- and heterooligomeric complexes. Binds the TPR motif-containing C-terminal of kinesin light chain, Klc. Pre-assembled syd scaffolding complexes are then transported as a cargo of kinesin, to the required subcellular location.

(UniProt, Q9GQF1)

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\syd using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

syd_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-1.25

Transcript Expression

expression microarray

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | male

(Arbeitman et al., 2004)

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | male

(Arbeitman et al., 2004)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

is_active_in presynaptic cytosol

inferred from direct assay

(Osaka et al., 2024)

located_in trans-Golgi network transport vesicle

inferred from direct assay

(Bowman et al., 2000)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\syd in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\syd

View exonic expression by tissue for Dmel\syd

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0024187

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

43905/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0024187

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0024187

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0024187

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG8110

Flygut - An atlas of the Drosophila adult midgut

FBgn0024187

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 11 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 7 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of syd

Transgenic constructs containing regulatory region of syd

Aberrations (Deficiencies and Duplications) ( 4 )

Inferred from experimentation ( 4 )

Gene disrupted in

Df(3L)Exel6279

(Ryder, 2004.4.26)

Df(3L)pbl-NR

(Bowman et al., 2000)

Df(3L)sw51

(Bowman et al., 2000)

Df(3L)syd^A2

(Bowman et al., 2000)

Inferred from location ( 8 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal - all die before end of larval stage | recessive

syd^Z

viable

syd^PL00426

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

syd^GD12383

viable, with Scer\GAL4^Mef2.PR

syd^GD12383

viable, with Scer\GAL4^pnr-MD237

syd^GD12383

viable, with Scer\GAL4^tin.CΔ4

syd^GD12383

Sterility

Allele

female semi-sterile, with Scer\GAL4^elav.PLu

syd^GD12383

fertile

syd^PL00426

Other Phenotypes

Allele

abnormal behavior | recessive

syd^Z

abnormal neuroanatomy

syd^unspecified

abnormal neuroanatomy | larval stage (with syd^2H)

syd^z4

abnormal neuroanatomy | larval stage (with syd^z4)

syd^2H

abnormal pain response | adult stage, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

syd^GD12383

decreased rate of movement | recessive

syd^Z

decreased size | adult stage, with Scer\GAL4^en.PU

decreased size | adult stage, with Scer\GAL4^nub.PU

decreased size | adult stage, with Scer\GAL4^ptc.PU

syd^GLC01419

decreased size | adult stage (with Df(3L)syd^A2)

syd^PL00426

increased cell death | larval stage, with Scer\GAL4^en.PU

syd^GLC01419

some die during larval stage | recessive

syd^Z

visible | adult stage, with Scer\GAL4^nub.PU

visible | adult stage, with Scer\GAL4^ptc.PU

syd^GLC01419

visible | adult stage (with Df(3L)syd^A2)

syd^PL00426

Phenotype manifest in

Allele

larva

syd^Z

larval abdominal segmental nerve

NMJ bouton | larval stage (with syd^2H)

syd^z4

NMJ bouton | larval stage (with syd^z4)

syd^2H

synaptic vesicle

syd^unspecified

wing, with Scer\GAL4^en.PU

wing, with Scer\GAL4^nub.PU

wing, with Scer\GAL4^ptc.PU

syd^GLC01419

wing (with Df(3L)syd^A2)

syd^PL00426

wing disc posterior compartment, with Scer\GAL4^en.PU

syd^GLC01419

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (10)

Hsap\SPAG9

14 of 14

Yes

Hsap\MAPK8IP3

12 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (9)

Rnor\Spag9

14 of 14

Yes

Rnor\Mapk8ip3

12 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (10)

Mmus\Spag9

14 of 14

Yes

Mmus\Mapk8ip3

12 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (6)

Xtro\spag9

10 of 13

Yes

Xtro\mapk8ip3

9 of 13

Yes

Xtro\ddx3x

2 of 13

Xtro\LOC100493724

1 of 13

Yes

Xtro\prkcg

1 of 13

Xtro\rilp

1 of 13

Danio rerio (Zebrafish) (10)

Drer\spag9b

14 of 14

Yes

Drer\spag9a

12 of 14

Yes

Drer\mapk8ip3

11 of 14

Yes

Drer\si:dkey-17m8.1

6 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (4)

Cele\unc-16

13 of 14

Yes

Cele\osg-1

1 of 14

Cele\rilp-1

1 of 14

Cele\vav-1

1 of 14

Anopheles gambiae (African malaria mosquito) (5)

Agam\AgaP_AGAP005042

12 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (0)

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:syd. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (4)

1 of 13

1 of 13

1 of 13

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Allele

Disease

Interaction

References

syd^GLC01419

ameliorates Alzheimer's disease 1

modeled by Hsap\APP^{695-Swedish.UAS.Tag:MYC}

(Du et al., 2021)

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

SPAG9; sperm associated antigen 9

14 of 14

605430

MAPK8IP3; mitogen-activated protein kinase 8 interacting protein 3

12 of 14

605431

NEURODEVELOPMENTAL DISORDER WITH OR WITHOUT VARIABLE BRAIN ABNORMALITIES; NEDBA

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

syd

suppressible

Diap1

(Ahmad et al., 2021)

syd

suppressible

Dronc

(Ahmad et al., 2021)

syd

suppressible

hpo

(Ahmad et al., 2021)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

bsk

suppressible

syd

(Ahmad et al., 2021)

hpo

suppressible

syd

(Ahmad et al., 2021)

yki

suppressible

syd

(Ahmad et al., 2021)

External Data

Subunit Structure (UniProtKB)

(UniProt, Q9GQF1 )

Linkouts

BioGRID - A database of protein and genetic interactions.

68706

DroID - A comprehensive database of gene and protein interactions.

FBgn0024187

MIST (protein-protein) - An integrated Molecular Interaction Database

43905

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Myogenesis

Class of Gene

gene_with_edited_transcript

(Rodriguez et al., 2012, Graveley et al., 2011, Stapleton et al., 2006)

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-21

Cytogenetic map

66A20-66A20

Sequence location

3L:7,916,650..7,936,120 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

66A20-66A20

Limits computationally determined from genome sequence between P{PZ}l(3)07217⁰⁸²²³&P{EP}Rac2^EP3118 and P{lacW}Nmt^j1C7

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

66B-66B

(Bowman et al., 1998)

Experimentally Determined Recombination Data

Location

3-21

(FlyBase, 2016)

3-18.4

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (9)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

81458

y¹ v¹; P{TKO.GS04706}attP40

15560

y¹ w^67c23; P{EPgy2}syd^EY02303

43232

y¹ v¹; P{TRiP.GLC01419}attP2/TM3, Sb¹

32017

Df(3L)syd^A2, pbl^A2 syd^A2/TM6B, Tb⁺

93529

w^*; TI{CRIMIC.TG4.1}syd^{CR60206-TG4.1}/TM3, Sb¹

91813

y¹ sc^* v¹ sev²¹; P{TOE.GS01194}attP40

32016

syd^z4 Diap1^th-1 st¹ cu¹ sr¹ e^s ca¹/TM3, red^* Ser¹

VDRC

v101459

P{KK109225}VIE-260B

v35346

w¹¹¹⁸; P{GD12383}v35346

Genomic Clones (17)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (53)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0024187

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RE03607

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0024187

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

syd directly binds Klc via the Klc tetratricopeptide repeat. Overall orientation not stated: syd+ pbl+

(Bowman et al., 2000)

The syd gene product mediates kinesin-dependent axonal transport by directly interacting with the Klc protein.

(Bowman et al., 2000)

Mutants show aberrant accumulations of axonal cargoes.

(Bowman et al., 2000)

Identification: Screen for new axonal transport mutants to identify components of the axonal transport process.

(Bowman et al., 1998)

Mutants display a larval distal sluggish phenotype and accumulations of motors and cargo in the larval segmental nerves.

(Bowman et al., 1998)

Relationship to Other Genes

Source for database merge of

Source for merge of: syd CG8110

(Drysdale, 2000.12.12, FlyBase, 1996-)

Additional comments

Source for merge of syd CG8110 was sequence comparison ( date:001216 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

CG8110

(Bonn et al., 2013, Howell et al., 2012, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Arbeitman et al., 2004, Drysdale, 2000.12.12)

JIP-3

(Hollenbeck, 2001)

Syd

(Ahmad et al., 2021, Du et al., 2021, Azevedo and Baylies, 2020, Bonn et al., 2013)

dsyd-1

(Scholz et al., 2019)

jip3

(Klinedinst et al., 2013)

syd

(Lee et al., 2023, Pang et al., 2021, Gene Disruption Project members, 2018-, Transgenic RNAi Project members, 2017-, Ashwal-Fluss et al., 2014, Bussell et al., 2014, Li et al., 2014, Schulman et al., 2014, Gunawardena et al., 2013, Klinedinst et al., 2013, Rodriguez et al., 2012, Zhao et al., 2011, Toda et al., 2008, Stapleton et al., 2006)

Name Synonyms

Sunday driver

(Azevedo and Baylies, 2020)

sunday driver

(Gunawardena et al., 2013, Howell et al., 2012, Toda et al., 2008, Mahr and Aberle, 2006, Bowman et al., 1998)

Secondary FlyBase IDs

FBgn0035826

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 83 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

43905

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9GQF1

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q9GQF1

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9GQF1

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0024187

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

43905/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0024187

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0024187

FlyMine - An integrated database for Drosophila genomics

FBgn0024187

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG8110

MARRVEL_MODEL - MARRVEL (model organism gene)

43905

Linkouts

BioGRID - A database of protein and genetic interactions.

68706

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0024187

DroID - A comprehensive database of gene and protein interactions.

FBgn0024187

DRSC - Results frm RNAi screens

FBgn0024187

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

syd_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0024187

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0024187

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG8110

Flygut - An atlas of the Drosophila adult midgut

FBgn0024187

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0024187

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC003186

MIST (protein-protein) - An integrated Molecular Interaction Database

43905

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Myogenesis

References (76)

The following external sites may use different assemblies or annotations than FlyBase.

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