FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\ana2
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General Information
Symbol
Dmel\ana2
Species
D. melanogaster
Name
anastral spindle 2
Annotation Symbol
CG8262
Feature Type
protein_coding_gene
FlyBase ID
FBgn0027513
Gene Model Status
Current
Stock Availability
4 publicly available
Gene Summary
anastral spindle 2 (ana2) encodes a centriole protein that is essential for centriole assembly, promoting the assembly of the central "cartwheel" structure. It may also have an independent role in promoting asymmetric divisions in larval neuroblasts. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)
All Summaries
Also Known As

STIL, Ana-2, BcDNA:LD22033

Key Links
Genomic Location
Cytogenetic map
44F3-44F3
Sequence location
Recombination map
2-59
RefSeq locus
NT_033778 REGION:8898729..8900211
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (10 terms)
Molecular Function (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (7 terms)
Terms Based on Experimental Evidence (7 terms)
CV Term
Evidence
References
involved_in asymmetric neuroblast division
inferred from mutant phenotype
(Wang et al., 2011)
involved_in centriole assembly
inferred from mutant phenotype
(Goshima et al., 2007)
inferred from mutant phenotype
(Jana et al., 2018)
involved_in centriole replication
inferred from mutant phenotype
(Dobbelaere et al., 2008)
inferred from direct assay
(Stevens et al., 2010)
involved_in centriole-centriole cohesion
inferred from direct assay
(Stevens et al., 2010)
involved_in ciliary basal body organization
inferred from mutant phenotype
(Jana et al., 2018)
inferred from genetic interaction with UniProtKB:Q9VAC8
(Jana et al., 2018)
involved_in establishment of mitotic spindle orientation
inferred from mutant phenotype
(Wang et al., 2011)
involved_in microtubule anchoring at centrosome
inferred from mutant phenotype
(Wang et al., 2011)
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (3 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
located_in centriole
inferred from direct assay
(Roque et al., 2012, Stevens et al., 2010, Dobbelaere et al., 2008)
located_in centrosome
inferred from direct assay
(Wang et al., 2011)
located_in ciliary basal body
inferred from direct assay
(Jana et al., 2018)
Terms Based on Predictions or Assertions (0 terms)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
    -
    Summaries
    Gene Snapshot
    anastral spindle 2 (ana2) encodes a centriole protein that is essential for centriole assembly, promoting the assembly of the central "cartwheel" structure. It may also have an independent role in promoting asymmetric divisions in larval neuroblasts. [Date last reviewed: 2019-03-07]
    Summary (Interactive Fly)

    centrosomal protein, regulates spindle orientation during neuroblast asymmetical division, tumor suppressor

    Gene Model and Products
    Number of Transcripts
    2
    Number of Unique Polypeptides
    2

    Please see the JBrowse view of Dmel\ana2 for information on other features

    To submit a correction to a gene model please use the Contact FlyBase form

    Protein Domains (via Pfam)
    Isoform displayed:
    Pfam protein domains
    InterPro name
    classification
    start
    end
    Protein Domains (via SMART)
    Isoform displayed:
    SMART protein domains
    InterPro name
    classification
    start
    end
    Structure
    Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9XZ31)

    If you don't see a structure in the viewer, refresh your browser.
    Model Confidence:
    • Very high (pLDDT > 90)
    • Confident (90 > pLDDT > 70)
    • Low (70 > pLDDT > 50)
    • Very low (pLDDT < 50)

    AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

    Experimentally Determined Structures
    Crossreferences
    PDB - An information portal to biological macromolecular structures
    Comments on Gene Model

    Gene model reviewed during 5.49

    Transcript Data
    Annotated Transcripts
    Name
    FlyBase ID
    RefSeq ID
    Length (nt)
    Assoc. CDS (aa)
    ana2-RA
    FBtr0088685
    NM_136571
    1432
    420
    ana2-RB
    FBtr0339310
    NM_001299287
    1429
    419
    Additional Transcript Data and Comments
    Reported size (kB)
    Comments
    External Data
    Crossreferences
    Polypeptide Data
    Annotated Polypeptides
    Name
    FlyBase ID
    Predicted MW (kDa)
    Length (aa)
    Theoretical pI
    UniProt
    RefSeq ID
    GenBank
    ana2-PA
    FBpp0087766
    46.5
    420
    7.86
    Q9XZ31
    NP_610415
    AAG22298
    ana2-PB
    FBpp0308416
    46.4
    419
    7.86
    A0A0B4LFU9
    NP_001286216
    AHN56014
    Polypeptides with Identical Sequences

    None of the polypeptides share 100% sequence identity.

    Additional Polypeptide Data and Comments
    Reported size (kDa)
    Comments
    External Data
    Crossreferences
    PDB - An information portal to biological macromolecular structures
    Linkouts
    Sequences Consistent with the Gene Model
    Mapped Features

    Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ana2 using the Feature Mapper tool.

    External Data
    Crossreferences
    Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
    Linkouts
    Expression Data
    Testis-specificity index

    The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

    1.51

    Transcript Expression
    in situ
    Stage
    Tissue/Position (including subcellular localization)
    Reference
    embryonic stage 1 -- 3
    organism

    Comment: maternally deposited

    (Fisher et al., 2012)
    embryonic stage 4 -- 6
    organism
    (Fisher et al., 2012)
    Additional Descriptive Data
    Marker for
     
    Subcellular Localization
    CV Term
    Polypeptide Expression
    Additional Descriptive Data
    Marker for
     
    Subcellular Localization
    CV Term
    Evidence
    References
    located_in centriole
    inferred from direct assay
    (Roque et al., 2012, Stevens et al., 2010, Dobbelaere et al., 2008)
    located_in centrosome
    inferred from direct assay
    (Wang et al., 2011)
    located_in ciliary basal body
    inferred from direct assay
    (Jana et al., 2018)
    Expression Deduced from Reporters
    High-Throughput Expression Data
    Associated Tools

    JBrowse - Visual display of RNA-Seq signals

    View Dmel\ana2 in JBrowse
    RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
    Bulk Downloads
    RNA-Seq RPKM values for all genes
    Reference
    See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
    Developmental Proteome: Life Cycle
    Developmental Proteome: Embryogenesis
    External Data and Images
    Linkouts
    BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
    DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
    EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
    FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
    FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
    Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
    Flygut - An atlas of the Drosophila adult midgut
    Images
    FlyBase Wiki
    Image Based Resources
    Alleles, Insertions, Transgenic Constructs, and Aberrations
    Classical and Insertion Alleles ( 7 )
    For All Classical and Insertion Alleles Show
     
    Other relevant insertions
    Transgenic Constructs ( 35 )
    For All Alleles Carried on Transgenic Constructs Show
    Transgenic constructs containing/affecting coding region of ana2
    Transgenic constructs containing regulatory region of ana2
    Aberrations (Deficiencies and Duplications) ( 1 )
    Inferred from experimentation ( 1 )
    Gene disrupted in
    Df(2R)Exel8048
    (Ryder, 2004.4.26)
    Inferred from location ( 5 )
    Variants
    Variant Molecular Consequences
    Alleles Representing Disease-Implicated Variants
    Phenotypes
    Orthologs
    Downloads
    Download All DIOPT Orthologs
    Human Orthologs (via DIOPT v9.1)
    Species\Gene Symbol
    Score
    Best Score
    Best Reverse Score
    Source
    Compara
    Domainoid
    eggNOG
    Hieranoid
    Homologene
    Inparanoid
    OMA
    OrthoDB
    OrthoFinder
    OrthoInspector
    orthoMCL
    Panther
    Phylome
    SonicParanoid
    Alignment
    Complementation?
    Transgene?
    Homo sapiens (Human) (0)
    Model Organism Orthologs (via DIOPT v9.1)
    Species\Gene Symbol
    Score
    Best Score
    Best Reverse Score
    Source
    Compara
    Domainoid
    eggNOG
    Hieranoid
    Homologene
    Inparanoid
    OMA
    OrthoDB
    OrthoFinder
    OrthoInspector
    orthoMCL
    Panther
    Phylome
    SonicParanoid
    Alignment
    Complementation?
    Transgene?
    Rattus norvegicus (Norway rat) (0)
    Mus musculus (laboratory mouse) (0)
    Xenopus tropicalis (Western clawed frog) (0)
    Danio rerio (Zebrafish) (0)
    Caenorhabditis elegans (Nematode, roundworm) (0)
    Anopheles gambiae (African malaria mosquito) (0)
    Arabidopsis thaliana (thale-cress) (0)
    Saccharomyces cerevisiae (Brewer's yeast) (0)
    Schizosaccharomyces pombe (Fission yeast) (0)
    Escherichia coli (enterobacterium) (0)
    Other Organism Orthologs (via OrthoDB)
    Data provided directly from OrthoDB:ana2. Refer to their site for version information.
    Paralogs
    Downloads
    Download All DIOPT Paralogs
    Paralogs (via DIOPT v9.1)
    Human Disease Associations
    FlyBase Human Disease Model Reports
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Allele
      Disease
      Evidence
      References
      Potential Models Based on Orthology ( 0 )
      Human Ortholog
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Allele
      Disease
      Interaction
      References
      Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
      Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
      Homo sapiens (Human)
      Gene name
      Score
      OMIM
      OMIM Phenotype
      DO term
      Complementation?
      Transgene?
      Functional Complementation Data
      Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
      Interactions
      Summary of Physical Interactions
      Interaction Browsers
      View in FlyBase Interactions Browser   View in MIST tool (external link)
      Please see the Physical Interaction reports below for full details
      protein-protein
      Physical Interaction
      Assay
      References
      ana2
      two hybrid, anti tag coimmunoprecipitation, anti tag western blot, pull down, x-ray crystallography, molecular sieving, Identification by mass spectrometry
      (McLamarrah et al., 2020, McLamarrah et al., 2018, Galletta et al., 2016, Cottee et al., 2015, Wang et al., 2011, Stevens et al., 2010)
      ana2 - Cen
      experimental knowledge based
      (Guruharsha et al., 2011)
      ana2 - Cep135
      anti tag coimmunoprecipitation, anti tag western blot, two hybrid, pull down, autoradiography
      (McLamarrah et al., 2020, Galletta et al., 2016, Dzhindzhev et al., 2014)
      ana2 - Cep97
      two hybrid
      (Galletta et al., 2016)
      ana2 - Cnb
      anti tag coimmunoprecipitation, peptide massfingerprinting, two hybrid
      (Januschke et al., 2013)
      ana2 - Cp110
      two hybrid
      (Galletta et al., 2016)
      ana2 - Fgop2
      experimental knowledge based
      (Guruharsha et al., 2011)
      ana2 - Lk6
      two hybrid
      (Galletta et al., 2016)
      ana2 - Myc
      anti tag coimmunoprecipitation, Identification by mass spectrometry
      (Vinayagam et al., 2016)
      ana2 - Nek2
      two hybrid
      (Galletta et al., 2016)
      ana2 - Pi3K21B
      anti tag coimmunoprecipitation, Identification by mass spectrometry
      (Vinayagam et al., 2016)
      ana2 - Plp
      two hybrid
      (Galletta et al., 2016)
      ana2 - Pten
      anti tag coimmunoprecipitation, Identification by mass spectrometry
      (Vinayagam et al., 2016)
      ana2 - RluA-2
      experimental knowledge based
      (Guruharsha et al., 2011)
      ana2 - S6k
      anti tag coimmunoprecipitation, Identification by mass spectrometry
      (Vinayagam et al., 2016)
      ana2 - SAK
      enzymatic study, Identification by mass spectrometry, anti tag coimmunoprecipitation, anti tag western blot, protein kinase assay, autoradiography, two hybrid, inferred by author, molecular weight estimation by staining, pull down
      (Ábrahám et al., 2023, McLamarrah et al., 2018, Dzhindzhev et al., 2017, Galletta et al., 2016, Dzhindzhev et al., 2014)
      ana2 - Sas-4
      x-ray crystallography, two hybrid, pull down, anti tag western blot, anti bait coimmunoprecipitation, western blot, autoradiography, anti tag coimmunoprecipitation, bio-layer interferometry, predetermined participant
      (McLamarrah et al., 2020, Moyer and Holland, 2019, McLamarrah et al., 2018, Galletta et al., 2016, Dzhindzhev et al., 2014, Zheng et al., 2014, Cottee et al., 2013)
      ana2 - Sas-6
      pull down, autoradiography, molecular sieving, confirmation by molecular weight, anti bait coimmunoprecipitation, anti tag western blot, anti tag coimmunoprecipitation, two hybrid
      (Ábrahám et al., 2023, Fatalska et al., 2020, Dzhindzhev et al., 2017, Galletta et al., 2016, Dzhindzhev et al., 2014, Stevens et al., 2010)
      ana2 - Slmap
      experimental knowledge based
      (Guruharsha et al., 2011)
      ana2 - Ubqn
      experimental knowledge based
      (Guruharsha et al., 2011)
      ana2 - ana1
      two hybrid
      (Galletta et al., 2016)
      ana2 - asl
      two hybrid, anti tag coimmunoprecipitation, anti tag western blot
      (McLamarrah et al., 2020, Galletta et al., 2016)
      ana2 - aurA
      two hybrid
      (Galletta et al., 2016)
      ana2 - cnn
      two hybrid, anti tag coimmunoprecipitation, anti tag western blot, pull down
      (McLamarrah et al., 2020, Galletta et al., 2016)
      ana2 - ctp
      anti tag coimmunoprecipitation, western blot, static light scattering, predetermined participant, isothermal titration calorimetry, anti tag western blot, two hybrid, x-ray crystallography
      (Slevin et al., 2014, Wang et al., 2011)
      ana2 - dos
      anti tag coimmunoprecipitation, peptide massfingerprinting
      (Friedman et al., 2011)
      ana2 - foxo
      anti tag coimmunoprecipitation, Identification by mass spectrometry
      (Vinayagam et al., 2016)
      ana2 - geminin
      experimental knowledge based
      (Guruharsha et al., 2011)
      ana2 - mud
      two hybrid
      (Wang et al., 2011)
      ana2 - nxf2
      experimental knowledge based
      (Guruharsha et al., 2011)
      ana2 - polo
      two hybrid
      (Galletta et al., 2016)
      ana2 - rictor
      anti tag coimmunoprecipitation, Identification by mass spectrometry
      (Vinayagam et al., 2016)
      ana2 - spd-2
      two hybrid
      (Galletta et al., 2016)
      ana2 - tacc
      two hybrid
      (Galletta et al., 2016)
      ana2 - woc
      experimental knowledge based
      (Guruharsha et al., 2011)
      Summary of Genetic Interactions
      Interaction Browsers
      Starting gene(s)
      Interaction type
      Interacting gene(s)
      Reference
      Starting gene(s)
      Interaction type
      Interacting gene(s)
      Reference
      External Data
      Linkouts
      BioGRID - A database of protein and genetic interactions.
      DroID - A comprehensive database of gene and protein interactions.
      MIST (protein-protein) - An integrated Molecular Interaction Database
      Pathways
      Signaling Pathways (FlyBase)
      Metabolic Pathways
      FlyBase
      External Links
      External Data
      Linkouts
      Class of Gene
      Genomic Location and Detailed Mapping Data
      Chromosome (arm)
      2R
      Recombination map
      2-59
      Cytogenetic map
      44F3-44F3
      Sequence location
      FlyBase Computed Cytological Location
      Cytogenetic map
      Evidence for location
      44F3-44F3
      Limits computationally determined from genome sequence between P{lacW}Dmnk16109&P{lacW}Gγ1k08017 and P{lacW}babok16912
      Experimentally Determined Cytological Location
      Cytogenetic map
      Notes
      References
      Experimentally Determined Recombination Data
      Location

      2-59

      (FlyBase, 2016)

      2-57.9

      (Comeron et al., 2012)
      Left of (cM)
      Right of (cM)
      Notes
      Stocks and Reagents
      Stocks (4)
      Genomic Clones (13)
       

      Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

      cDNA Clones (25)
       

      Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

      cDNA clones, fully sequenced
      BDGP DGC clones
      Other clones
      Drosophila Genomics Resource Center cDNA clones

      For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

      cDNA Clones, End Sequenced (ESTs)
      BDGP DGC clones
      Other clones
      RNAi and Array Information
      Linkouts
      DRSC - Results frm RNAi screens
      Antibody Information
      Laboratory Generated Antibodies
       

      polyclonal

      (Boese et al., 2018, Wang et al., 2011, Stevens et al., 2010)

      monoclonal

      (Zheng et al., 2014)
      Commercially Available Antibodies
       
      Cell Line Information
      Publicly Available Cell Lines
       
        Other Stable Cell Lines
         

        • New stable cell line derived from S2-ThermoFischer : A CRISPR method for S2 cells that can be adapted for both knock-in and knock-out of any gene was developed. The followind lines were created (author designations): S2-Cas9Par, S2-Plk4 CRISPR null line 1, S2-Plk4 CRISPR null line 2.2, S2-Plk4 CRISPR null line 7, S2-Ana2 CRISPR null line 2, S2-Ana2 CRISPR null line 4, S2-Ana2 CRISPR null line 5, S2-ana2 CRISPR null line 12, Ana2 CRISPR null line 15, and Ana2 CRISPR null line 17. Note that Plk4 is SAK in FlyBase and Ana2 is ana2 in FlyBase.

          (Ryniawec et al., 2024)

        • New stable cell line derived from S2-ThermoFischer : Centriolar proteins were tagged with GFP at either the N- or C- terminus and used to create stable S2 cell lines. S2 cell lines constitutively expressing the following constructs were created: asl-GFP, Sas-6-GFP, ana1-GFP, GFP-ana1, Cep135-GFP, ana3-GFP, Rcd4-GFP, ana2-GFP, GFP-asl.

          (Tian et al., 2021)
        Other Comments

        ana2 is a centriole component with a unique asymmetric localization.

        (Stevens et al., 2010)

        ana2 is involved in centriole duplication.

        (Dobbelaere et al., 2008)

        RNAi screen using dsRNA made from templates generated with primers directed against this gene results in the spindles that are either anastral (no γ-tubulin staining at the poles) or monastral (only one pole with γ-tubulin staining) when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.

        (Goshima et al., 2007)
        Relationship to Other Genes
        Source for database merge of
        Additional comments
        Nomenclature History
        Source for database identify of

        Source for identity of: ana2 CG8262

        (Goshima et al., 2007)
        Nomenclature comments
        Etymology

        The name "anastral spindle 2" refers to the cellular phenotype observed following treatment of S2 cells with dsRNA directed against this gene.

        (Goshima et al., 2007)
        Synonyms and Secondary IDs (12)
        Reported As
        Symbol Synonym
        ANA2
        (Pimenta-Marques et al., 2024)
        Ana-2
        (Naveed et al., 2018, Januschke et al., 2013)
        Ana2
        (Mengistu, 2025, Wong et al., 2025, Ryniawec et al., 2024, Frappaolo et al., 2022, Szikora et al., 2021, Tian et al., 2021, Wainman, 2021, Dobbelaere et al., 2020, Fatalska et al., 2020, Gartenmann et al., 2020, Ito et al., 2019, Moyer and Holland, 2019, Boese et al., 2018, Jana et al., 2018, McLamarrah et al., 2018, Tillery et al., 2018, Cottee et al., 2017, Dzhindzhev et al., 2017, Lattao et al., 2017, Jana et al., 2016, Khire et al., 2016, Nashchekin et al., 2016, Saurya et al., 2016, Cottee et al., 2015, Fu et al., 2015, Homem et al., 2015, Khire et al., 2015, Slevin et al., 2014, Zheng et al., 2014, Brownlee and Rogers, 2013, Marthiens et al., 2012, Conduit et al., 2010, Stevens et al., 2010, Stevens et al., 2010, Dobbelaere et al., 2008, Goshima et al., 2007, Goshima et al., 2007)
        BcDNA:LD22033
        (Giot et al., 2003)
        CG8262
        (Hosono et al., 2015, Januschke et al., 2013, Dobbelaere et al., 2008, Goshima et al., 2007)
        STIL
        (Marthiens and Basto, 2020, Fu et al., 2015, Brownlee and Rogers, 2013)
        ana2
        (Debec et al., 2020, Blake-Hedges and Megraw, 2019, Jo et al., 2019, Aydogan et al., 2018, Saurya et al., 2016, Baumbach et al., 2015, Khire et al., 2015, Van Bortle et al., 2015, Luck et al., 2014, Cordes et al., 2013, Franz et al., 2013, Roque et al., 2012, Friedman et al., 2011, Wang et al., 2011)
        dSTIL
        (Cottee et al., 2013)
        Name Synonyms
        Anastral spindle 2
        (Homem et al., 2015)
        CG8262
        anastral spindle 2
        (Wang et al., 2011)
        anastral spindle phenotype 2
        (Goshima et al., 2007)
        anastral spindle-2
        (Slevin et al., 2014)
        Secondary FlyBase IDs
          Datasets (0)
          Study focus (0)
          Experimental Role
          Project
          Project Type
          Title
          Study result (0)
          Result
          Result Type
          Title
          External Crossreferences and Linkouts ( 37 )
          Sequence Crossreferences
          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
          UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
          UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
          Other crossreferences
          AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
          BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
          DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
          EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
          FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
          FlyMine - An integrated database for Drosophila genomics
          KEGG Genes - Molecular building blocks of life in the genomic space.
          MARRVEL_MODEL - MARRVEL (model organism gene)
          PDB - An information portal to biological macromolecular structures
          Linkouts
          BioGRID - A database of protein and genetic interactions.
          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
          DroID - A comprehensive database of gene and protein interactions.
          DRSC - Results frm RNAi screens
          Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
          FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
          Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
          Flygut - An atlas of the Drosophila adult midgut
          Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
          MIST (protein-protein) - An integrated Molecular Interaction Database
          References (84)