FlyBase Gene Report: Dmel\Pbp95

General Information

Symbol

Dmel\Pbp95

Species

D. melanogaster

Name

PSEA-binding protein 95kD

Annotation Symbol

CG2702

Feature Type

protein_coding_gene

FlyBase ID

FBgn0037540

Gene Model Status

Current

Stock Availability

9 publicly available

Gene Summary

PSEA-binding protein 95kD (Pbp95) encodes a protein that functions as one of three subunits of the small nuclear RNA (snRNA) activating protein complex, which binds as a complex to a proximal sequence element A (PSEA) to activate transcription of snRNA genes. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

DmSNAP190, DmPBP

Key Links

Genomic Location

Cytogenetic map

84E8-84E8

Sequence location

3R:8,013,791..8,016,610 [+]

Recombination map

3-48

RefSeq locus

NT_033777 REGION:8013791..8016610

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (11 terms)

Molecular Function (6 terms)

Terms Based on Experimental Evidence (6 terms)

CV Term

Evidence

References

enables bent DNA binding

inferred from direct assay

(Hardin et al., 2000)

enables DNA binding

inferred from direct assay

(Li et al., 2004, Su et al., 1997)

enables protein binding

inferred from physical interaction with FLYBASE:Pbp45; FB:FBgn0038371

(Hung et al., 2009)

contributes_to RNA polymerase II cis-regulatory region sequence-specific DNA binding

inferred from direct assay

(Lai et al., 2008)

enables RNA polymerase II cis-regulatory region sequence-specific DNA binding

inferred from direct assay

(Kang et al., 2014, Kim et al., 2010, Hung et al., 2009)

enables RNA polymerase III type 3 promoter sequence-specific DNA binding

inferred from direct assay

(Kang et al., 2014, Kim et al., 2010)

enables sequence-specific DNA binding

inferred from direct assay

(Wang and Stumph, 1998)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

contributes_to RNA polymerase II cis-regulatory region sequence-specific DNA binding

inferred from biological aspect of ancestor with PANTHER:PTN005312741

(GO Reference Genome Project, 2011-)

enables RNA polymerase III type 3 promoter sequence-specific DNA binding

inferred from biological aspect of ancestor with PANTHER:PTN005312741

(GO Reference Genome Project, 2011-)

Biological Process (4 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

involved_in protein-DNA complex assembly

inferred from direct assay

(Li et al., 2004, Wang and Stumph, 1998)

involved_in snRNA transcription by RNA polymerase III

inferred from direct assay

(Wang and Stumph, 1998, Su et al., 1997)

involved_in snRNA transcription by RNA polymerase II

inferred from direct assay

(Wang and Stumph, 1998, Su et al., 1997)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in snRNA transcription by RNA polymerase III

inferred from biological aspect of ancestor with PANTHER:PTN005312741

(GO Reference Genome Project, 2011-)

involved_in snRNA transcription by RNA polymerase II

inferred from biological aspect of ancestor with PANTHER:PTN005312741

(GO Reference Genome Project, 2011-)

inferred by curator from GO:0000978,GO:0019185

(Kim et al., 2010, Hung et al., 2009)

involved_in transcription by RNA polymerase III

inferred by curator from GO:0001006,GO:0019185

(Kim et al., 2010)

Cellular Component (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

part_of snRNA-activating protein complex

inferred from physical interaction with FLYBASE:Pbp45; FB:FBgn0038371

(Hung et al., 2009)

inferred from physical interaction with FLYBASE:Pbp49; FB:FBgn0260398

(Hung et al., 2009)

inferred from direct assay

(Kim et al., 2010, Lai et al., 2008)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

part_of snRNA-activating protein complex

inferred from biological aspect of ancestor with PANTHER:PTN005312741

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

SANT-MYB DOMAIN TRANSCRIPTION FACTORS

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Gene Group (FlyBase)

SANT-MYB DOMAIN TRANSCRIPTION FACTORS -: The SANT-MYB domain transcription factors are sequence specific DNA-binding proteins that regulate transcription. The Myb domain is a DNA binding helix-turn-helix domain that contains three tandem repeats of 50 amino acids, termed R1, R2 and R3. The α-helical repeats R2 and R3 are involved in the DNA interaction. (Adapted from PMID:10378697).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Pbp95 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VHX0)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.47

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Pbp95-RA

FBtr0081786

NM_141503

2649

721

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Pbp95-PA

FBpp0081282

84.0

721

9.26

Q9VHX0

NP_649760

AAF54179

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q9VHX0

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pbp95 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Pbp95_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.39

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

part_of snRNA-activating protein complex

inferred from physical interaction with FLYBASE:Pbp45; FB:FBgn0038371

(Hung et al., 2009)

inferred from physical interaction with FLYBASE:Pbp49; FB:FBgn0260398

(Hung et al., 2009)

inferred from direct assay

(Kim et al., 2010, Lai et al., 2008)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Pbp95 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Pbp95

View exonic expression by tissue for Dmel\Pbp95

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0037540

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

40949/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0037540

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0037540

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0037540

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG2702

Flygut - An atlas of the Drosophila adult midgut

FBgn0037540

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 2 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 8 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Pbp95

Transgenic constructs containing regulatory region of Pbp95

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(3R)Exel6263

(Ryder, 2004.4.26)

Inferred from location ( 14 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Pbp95^GD9812

viable, with Scer\GAL4^Mef2.PR

Pbp95^GD9812

viable, with Scer\GAL4^pnr-MD237

Pbp95^GD9812

viable, with Scer\GAL4^tin.CΔ4

Pbp95^GD9812

Other Phenotypes

Allele

visible, with Scer\GAL4^pnr-MD237

Pbp95^GD9812

Phenotype manifest in

Allele

chaeta, with Scer\GAL4^pnr-MD237

Pbp95^GD9812

mesonotum, with Scer\GAL4^pnr-MD237

Pbp95^GD9812

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (7)

Hsap\SNAPC4

5 of 14

Yes

Hsap\CDC5L

1 of 14

Hsap\DMTF1

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (6)

Rnor\Snapc4

4 of 14

Yes

Rnor\Cdc5l

1 of 14

Rnor\Dmtf1

1 of 14

Yes

Rnor\Mybl1

1 of 14

Rnor\Mybl2

1 of 14

Rnor\Ttf1

1 of 14

Yes

Mus musculus (laboratory mouse) (8)

Mmus\Snapc4

4 of 14

Yes

Mmus\Cdc5l

1 of 14

Mmus\Dmtf1l

1 of 14

Yes

Mmus\Dmtf1

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Xenopus tropicalis (Western clawed frog) (2)

Xtro\ndrg4

3 of 13

Yes

Xtro\snapc4

2 of 13

Danio rerio (Zebrafish) (6)

Drer\snapc4

4 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\ttf1.6

1 of 14

Yes

Caenorhabditis elegans (Nematode, roundworm) (2)

Cele\snpc-4

4 of 14

Yes

Cele\cdc-5L

1 of 14

Anopheles gambiae (African malaria mosquito) (3)

Agam\AgaP_AGAP001156

10 of 12

Yes

Agam\AgaP_AGAP002954

1 of 12

Agam\AgaP_AGAP008160

1 of 12

Arabidopsis thaliana (thale-cress) (138)

Atha\MYB4R1

3 of 13

Yes

Atha\AS1

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Atha\MYB11

1 of 13

Yes

Atha\MYB12

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Atha\MYB112

1 of 13

Atha\MYB113

1 of 13

Atha\MYB114

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Atha\MYBL2

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (4)

Scer\BAS1

1 of 13

Yes

Scer\CEF1

1 of 13

Yes

Scer\NSI1

1 of 13

Yes

Scer\REB1

1 of 13

Yes

Schizosaccharomyces pombe (Fission yeast) (4)

Spom\cdc5

1 of 12

Yes

Spom\eta2

1 of 12

Yes

Spom\reb1

1 of 12

Yes

Spom\rtf1

1 of 12

Yes

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Pbp95. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (2)

Cdc5

1 of 13

Myb

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

SNAPC4; small nuclear RNA activating complex polypeptide 4

5 of 14

602777

NEURODEVELOPMENTAL DISORDER WITH MOTOR REGRESSION, PROGRESSIVE SPASTIC PARAPLEGIA, AND OROMOTOR DYSFUNCTION; NEDRSO

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Pbp95 - Bdp1

electrophoretic mobility shift assay, electrophoretic mobility supershift assay, autoradiography, protein cross-linking with a bifunctional reagent, Identification by mass spectrometry

(Kim et al., 2020, Verma et al., 2018)

Pbp95 - CG11178

experimental knowledge based

(Guruharsha et al., 2011)

Pbp95 - CkIIα-i3

two hybrid

(Hu et al., 2017.6.13)

Pbp95 - E5

two hybrid array

(Shokri et al., 2019)

Pbp95 - Pbp45

anti tag coimmunoprecipitation, western blot, affinity chromatography technology, ion exchange chromatography, molecular weight estimation by staining, electrophoretic mobility supershift assay, autoradiography, molecular sieving

(Hung and Stumph, 2012, Hung et al., 2009, Lai et al., 2008, Li et al., 2004, Wang and Stumph, 1998)

Pbp95 - Pbp49

anti tag coimmunoprecipitation, western blot, electrophoretic mobility supershift assay, autoradiography, ion exchange chromatography, molecular weight estimation by staining, molecular sieving

(Hung et al., 2009, Lai et al., 2008, Li et al., 2004, Wang and Stumph, 1998)

Pbp95 - otp

two hybrid

(Hu et al., 2017.6.13)

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0037540

MIST (protein-protein) - An integrated Molecular Interaction Database

40949

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

RNA polymerase II transcribes snRNA genes

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-48

Cytogenetic map

84E8-84E8

Sequence location

3R:8,013,791..8,016,610 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

84E8-84E8

Limits computationally determined from genome sequence between P{EP}EP3060^EP3060 and P{PZ}grn⁰⁵⁹³⁰

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-48

(FlyBase, 2016)

3-44.7

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (9)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

79974

y¹ sc^* v¹ sev²¹; P{TOE.GS02677}attP40

83818

y¹ sc^* v¹ sev²¹; P{TKO.GS04491}attP40

67281

y¹ sc^* v¹ sev²¹; P{TRiP.HMC06384}attP40

37072

y¹ w^*; Mi{MIC}Pbp95^MI03676/TM3, Sb¹ Ser¹

FlyORF

F000272

M{UAS-Pbp95.ORF.3xHA.GW}ZH-86Fb

NIG-Fly

HMJ22798

y¹ v¹; P{TRiP.HMJ22798}attP40/CyO

VDRC

v33557

w¹¹¹⁸; P{GD9812}v33557

v33558

w¹¹¹⁸; P{GD9812}v33558

v341302

P{hsFLP}1, y¹ w¹¹¹⁸; P{HD_CFD00354}attP40/CyO-GFP

Genomic Clones (19)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (18)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

LD18233

Other clones

DPiM_LD18233

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0037540

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0037540

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Li et al., 2004)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

New stable cell line derived from S2-unspecified : S2 cells were stably transfected with inducible Tag:FLAG-tagged full-length as well as N-terminally and C-terminally truncated Pbp95 constructs. Each was co-transfected with complementary full length Pbp45 and Pbp49 constructs.
(Hung et al., 2009)

Other Comments

Area matching Drosophila EST AA392117.

(Davies, 2001.3.15)

The Pbp95 product cross-links to positions in the 3' half of the PSEA element found in the promoters of snRNA genes. However, there are significant differences in the cross-linking pattern when PSEAs from a U1 or U6 gene are compared.

(Wang and Stumph, 1998)

Relationship to Other Genes

Source for database merge of

Source for merge of: CG2702 BEST:LD28511

(Rana, 2004.7.8)

Source for merge of: CG2702 anon-WO0118547.359

(FlyBase, 1996-)

Additional comments

Source for merge of CG2702 anon-WO0118547.359 was sequence comparison ( date:051113 ).

(Wang and Stumph, 1998, FlyBase, 1996-)

Nomenclature History

Source for database identify of

Source for identity of: Pbp95 CG2702

(Li et al., 2004)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (11)

Reported As

Symbol Synonym

BEST:LD28511

CG2702

(National Institute of Genetics Fly Stocks, 2023-, Hosono et al., 2015, Perkins et al., 2009, Kwon et al., 2008, Li et al., 2004)

DmPBP

(Hardin et al., 2000, Wang and Stumph, 1998, Su et al., 1997)

DmPBP95

(Li et al., 2004)

DmSNAP190

(Hung and Stumph, 2011, Kim et al., 2010, Hung et al., 2009, Lai et al., 2008, Li et al., 2004)

DmSNAPc

(Kim et al., 2010)

Pbp95

(Xu et al., 2025, Malik et al., 2024, Shokri et al., 2019, Bischof et al., 2018, Hu et al., 2017.6.13, Transgenic RNAi Project members, 2017-, Schertel et al., 2015, Swaminathan et al., 2010)

anon-WO0118547.359

Name Synonyms

CG2702

Drosophila melanogaster PSE-binding protein 95-kDa subunit

(Wang and Stumph, 1998)

PSEA-binding protein

(Hardin et al., 2000)

PSEA-binding protein 95kD

Secondary FlyBase IDs

FBgn0046261
FBgn0062071
FBgn0022383

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 40 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

40949

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VHX0

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Q9VHX0

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VHX0

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0037540

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

40949/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0037540

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0037540

FlyMine - An integrated database for Drosophila genomics

FBgn0037540

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG2702

MARRVEL_MODEL - MARRVEL (model organism gene)

40949

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0037540

DroID - A comprehensive database of gene and protein interactions.

FBgn0037540

DRSC - Results frm RNAi screens

FBgn0037540

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Pbp95_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0037540

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0037540

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG2702

Flygut - An atlas of the Drosophila adult midgut

FBgn0037540

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0037540

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

MIST (protein-protein) - An integrated Molecular Interaction Database

40949

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

RNA polymerase II transcribes snRNA genes

References (59)

The following external sites may use different assemblies or annotations than FlyBase.

-0.39

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