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Citation
Gonzalez, C. (2013). Drosophila melanogaster: a model and a tool to investigate malignancy and identify new therapeutics.  Nat. Rev. Cancer 13(3): 172--183.
FlyBase ID
FBrf0220847
Publication Type
Review
Abstract

For decades, lower-model organisms such as Drosophila melanogaster have often provided the first glimpse into the mechanism of action of human cancer-related proteins, thus making a substantial contribution to elucidating the molecular basis of the disease. More recently, D. melanogaster strains that are engineered to recapitulate key aspects of specific types of human cancer have been paving the way for the future role of this 'workhorse' of biomedical research, helping to further investigate the process of malignancy, and serving as platforms for therapeutic drug discovery.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Nat. Rev. Cancer
    Title
    Nature Reviews. Cancer
    Publication Year
    2001-
    ISBN/ISSN
    1474-175X 1474-1768
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