FlyBase Gene Report: Rcom\RT

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Gene: Rcom\RT

General Information

Symbol

Rcom\RT

Species

R. communis

Name

Ricin toxin gene

Annotation Symbol

Feature Type

engineered_foreign_gene

FlyBase ID

FBgn0014450

Gene Model Status

Stock Availability

6 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Interactive Fly

Also Known As

ricin, ricinA, RTA

Foreign Gene Data

Foreign sequence; species == Ricinus communis; gene == 'RT, Ricin toxin gene'; UniProt/Swiss- Prot:P02880 .

(FlyBase Curators, 1992-)

Summaries

Alleles, Insertions, Transgenic Constructs

Classical and Insertion Alleles ( 1 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 4 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Rcom\RT

Transgenic constructs containing regulatory region of Rcom\RT

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^30A

Rcom\RT^A.UAS

lethal, with Scer\GAL4^238Y

Rcom\RT^A.UAS

lethal, with Scer\GAL4^ato.3.6

Rcom\RT^A.UAS

lethal, with Scer\GAL4^c708a

Rcom\RT^A.UAS

lethal, with Scer\GAL4^elav.PLu

Rcom\RT^A.UAS

lethal, with Scer\GAL4^how-24B

Rcom\RT^A.UAS

lethal, with Scer\GAL4^Ilp2.PR

Rcom\RT^A.UAS

lethal, with Scer\GAL4^nSyb.PS

Rcom\RT^A.UAS

lethal, with Scer\GAL4^Rab27.ORF

Rcom\RT^A.UAS

lethal, with Scer\GAL4^VT024615

Rcom\RT^A.UAS

lethal | embryonic stage, with Scer\GAL4^A4

Rcom\RT^A.UAS

lethal | embryonic stage, with Scer\GAL4^PDM1

Rcom\RT^A.UAS

lethal | larval stage, with Scer\GAL4^A4

Rcom\RT^A.UAS

lethal | larval stage, with Scer\GAL4^PDM1

Rcom\RT^A.UAS

lethal | pupal stage, with Scer\GAL4^A4

Rcom\RT^A.UAS

lethal | pupal stage, with Scer\GAL4^PDM1

Rcom\RT^A.UAS

lethal - all die before end of larval stage, with Scer\GAL4^VT014429

Rcom\RT^A.UAS

lethal - all die before end of pupal stage, with Scer\GAL4^P5-GAL4

Rcom\RT^A.UAS

lethal - all die before end of pupal stage, with Scer\GAL4^VG4

Rcom\RT^A.UAS

lethal - all die before end of pupal stage, with Scer\GAL4^wg-Cir2

Rcom\RT^A.UAS

lethal - all die during embryonic stage, with Scer\GAL4^AG2

Rcom\RT^A.UAS

lethal - all die during embryonic stage, with Scer\GAL4^AP1

Rcom\RT^A.UAS

lethal - all die during embryonic stage, with Scer\GAL4^bi-omb1-GAL4

Rcom\RT^A.UAS

lethal - all die during embryonic stage, with Scer\GAL4^bi-omb3-GAL4

Rcom\RT^A.UAS

lethal - all die during embryonic stage, with Scer\GAL4^fj-VG1

Rcom\RT^A.UAS

lethal - all die during embryonic stage, with Scer\GAL4^N-GAL4

Rcom\RT^A.UAS

lethal - all die during embryonic stage, with Scer\GAL4^ptc-Cwh1

Rcom\RT^A.UAS

lethal - all die during embryonic stage | heat sensitive, with Scer\GAL4^how-24B

Rcom\RT^A-cs2.UAS

lethal - all die during embryonic stage | heat sensitive, with Scer\GAL4^Ugt36A1.PK

Rcom\RT^A.UAS

partially lethal | heat sensitive

Rcom\RT^RAcs2.5

Rcom\RT^A-cs2.sev

viable, with Scer\GAL4^A6

Rcom\RT^A.UAS

viable, with Scer\GAL4^AG1

Rcom\RT^A.UAS

viable, with Scer\GAL4^AM1

Rcom\RT^A.UAS

viable, with Scer\GAL4^Eq2

Rcom\RT^A.UAS

viable, with Scer\GAL4^Eq

Rcom\RT^A.UAS

viable, with Scer\GAL4^GMR16A06

Rcom\RT^A.UAS

viable, with Scer\GAL4^hth-P1-GAL4

Rcom\RT^A.UAS

viable, with Scer\GAL4^MT11

Rcom\RT^A.UAS

viable, with Scer\GAL4^nAChRα6-P2

Rcom\RT^A.UAS

viable, with Scer\GAL4^wor-Cir1

Rcom\RT^A.UAS

viable | cold sensitive, with Scer\GAL4^GMR.PF

Rcom\RT^A-cs2.UAS

Sterility

Allele

Rcom\RT^A-cs2.sev

Other Phenotypes

Allele

abnormal aging, with Scer\GAL4^ato.3.6

Rcom\RT^A.UAS

abnormal auditory perception, with Scer\GAL4^JO15, Scer\GAL4^NP1046

Rcom\RT^A.UAS

abnormal cell death, with Scer\GAL4¹⁵⁸

Rcom\RT^A.UAS

abnormal cell death, with Scer\GAL4^C321c

Rcom\RT^A.UAS

abnormal cell death, with Scer\GAL4^s.gcm

Rcom\RT^A.UAS

abnormal locomotor behavior | conditional, with Scer\GAL4^NP6250

Rcom\RT^A.UAS

abnormal memory, with Scer\GAL4^CaMKII.7

Rcom\RT^A-cs2.UAS

abnormal memory, with Scer\GAL4^cer-Mz1180

Rcom\RT^A-cs2.UAS

abnormal memory, with Scer\GAL4^ChAT.7.4

Rcom\RT^A-cs2.UAS

abnormal memory, with Scer\GAL4^ChAT.7.4, Scer\GAL80^Mef2.mb247

Rcom\RT^A-cs2.UAS

abnormal memory, with Scer\GAL4^cry.PU

Rcom\RT^A-cs2.UAS

abnormal memory, with Scer\GAL4^Ddc.PL

Rcom\RT^A-cs2.UAS

abnormal memory, with Scer\GAL4^E0946

Rcom\RT^A-cs2.UAS

abnormal memory, with Scer\GAL4^G0338

Rcom\RT^A-cs2.UAS

abnormal memory, with Scer\GAL4^G0431

Rcom\RT^A-cs2.UAS

abnormal memory, with Scer\GAL4^Hn.493

Rcom\RT^A-cs2.UAS

abnormal memory, with Scer\GAL4^Hn.996

Rcom\RT^A-cs2.UAS

abnormal memory, with Scer\GAL4^per.PK

Rcom\RT^A-cs2.UAS

abnormal memory | adult stage | heat sensitive, with Hsap\RELA^AD.R12C11, Scer\GAL4^DBD.R14C08

Rcom\RT^A-cs2.UAS

abnormal memory | adult stage | heat sensitive, with Hsap\RELA^AD.R14C08, Scer\GAL4^DBD.R15B01

Rcom\RT^A-cs2.UAS

abnormal memory | adult stage | heat sensitive, with Hsap\RELA^AD.R20A02, Scer\GAL4^DBD.R94B10

Rcom\RT^A-cs2.UAS

abnormal memory | adult stage | heat sensitive, with Hsap\RELA^AD.R40B08, Scer\GAL4^DBD.R23C06

Rcom\RT^A-cs2.UAS

abnormal memory | adult stage | heat sensitive, with Hsap\RELA^AD.R52G04, Scer\GAL4^DBD.R94B10

Rcom\RT^A-cs2.UAS

abnormal memory | adult stage | heat sensitive, with Scer\GAL4^BG01228

Rcom\RT^A-cs2.UAS

abnormal memory | adult stage | heat sensitive, with Scer\GAL4^BG01228, Scer\GAL4^VT016811

Rcom\RT^A-cs2.UAS

abnormal memory | adult stage | heat sensitive, with Scer\GAL4^BG01228, Scer\GAL4^VT016811, Scer\GAL4^VT044170

Rcom\RT^A-cs2.UAS

abnormal memory | adult stage | heat sensitive, with Scer\GAL4^BG01228, Scer\GAL4^VT044170

Rcom\RT^A-cs2.UAS

abnormal memory | adult stage | heat sensitive, with Scer\GAL4^VT007759

Rcom\RT^A-cs2.UAS

abnormal memory | adult stage | heat sensitive, with Scer\GAL4^VT016811

Rcom\RT^A-cs2.UAS

abnormal memory | adult stage | heat sensitive, with Scer\GAL4^VT016811, Scer\GAL4^VT044170

Rcom\RT^A-cs2.UAS

abnormal memory | adult stage | heat sensitive, with Scer\GAL4^VT026347

Rcom\RT^A-cs2.UAS

abnormal memory | adult stage | heat sensitive, with Scer\GAL4^VT041043

Rcom\RT^A-cs2.UAS

abnormal memory | adult stage | heat sensitive, with Scer\GAL4^VT044170

Rcom\RT^A-cs2.UAS

abnormal memory | adult stage | heat sensitive, with Scer\GAL4^VT048852

Rcom\RT^A-cs2.UAS

abnormal neuroanatomy, with Scer\GAL4^eve.RN2

Rcom\RT^A.UAS

abnormal neuroanatomy, with Scer\GAL4^ey-OK107

Rcom\RT^A-cs2.UAS

abnormal neuroanatomy, with Scer\GAL4^how-24B

Rcom\RT^A.UAS

abnormal neuroanatomy, with Scer\GAL4^Mz19

Rcom\RT^A.UAS

abnormal neuroanatomy, with Scer\GAL4^Mz520

Rcom\RT^A.UAS

abnormal neuroanatomy, with Scer\GAL4^Or47b.7.467

Rcom\RT^A.UAS

abnormal neuroanatomy, with Scer\GAL4^Or88a.PW

Rcom\RT^A.UAS

abnormal neuroanatomy | adult stage, with Scer\FLP1^ey.PN, Scer\GAL4^amos.PZ

Rcom\RT^A.UAS.FRT

abnormal neuroanatomy | adult stage, with Scer\FLP1^ey.PN, Scer\GAL4^NP6558

Rcom\RT^A.UAS.FRT

decreased occurrence of cell division | cell non-autonomous | larval stage, with Scer\GAL4^ap-md544

Rcom\RT^A-cs2.UAS

decreased occurrence of cell division | larval stage, with Scer\GAL4^cad-em459

some die during embryonic stage, with Scer\GAL4^AG2

Rcom\RT^A.UAS

some die during embryonic stage, with Scer\GAL4^AP1

Rcom\RT^A.UAS

some die during embryonic stage, with Scer\GAL4^bi-omb1-GAL4

Rcom\RT^A.UAS

some die during embryonic stage, with Scer\GAL4^bi-omb3-GAL4

Rcom\RT^A.UAS

some die during embryonic stage, with Scer\GAL4^fj-VG1

Rcom\RT^A.UAS

some die during embryonic stage, with Scer\GAL4^N-GAL4

Rcom\RT^A.UAS

some die during embryonic stage, with Scer\GAL4^ptc-Cwh1

Rcom\RT^A.UAS

some die during embryonic stage | heat sensitive, with Scer\GAL4^how-24B

Rcom\RT^A-cs2.UAS

some die during embryonic stage | heat sensitive, with Scer\GAL4^Ugt36A1.PK

Rcom\RT^A.UAS

some die during pupal stage, with Scer\GAL4^P5-GAL4

Rcom\RT^A.UAS

some die during pupal stage, with Scer\GAL4^VG4

Rcom\RT^A.UAS

some die during pupal stage, with Scer\GAL4^wg-Cir2

Rcom\RT^A.UAS

visible, with Scer\GAL4^Eq

Rcom\RT^A.UAS

visible, with Scer\GAL4^nAChRα6-P2

Rcom\RT^A.UAS

visible, with Scer\GAL4^Ugt36A1.PK

Rcom\RT^A.UAS

visible | RU486 conditional, with Scer\GAL4^{GMR.in.Switch.PR}

Rcom\RT^A.UAS

visible | temperature conditional, with Scer\GAL4^ap-md544

Rcom\RT^A-cs2.UAS

visible | temperature conditional, with Scer\GAL4^bbg-C96

Rcom\RT^A-cs2.UAS

visible | temperature conditional, with Scer\GAL4^brk.PU

Rcom\RT^A-cs2.UAS

visible | temperature conditional, with Scer\GAL4^ci.PU

Rcom\RT^A-cs2.UAS

visible | temperature conditional, with Scer\GAL4^en-e16E

Rcom\RT^A-cs2.UAS

Phenotype manifest in

Allele

adult antennal lobe, with Scer\FLP1^ey.PN, Scer\GAL4^amos.PZ

Rcom\RT^A.UAS.FRT

adult antennal lobe, with Scer\FLP1^ey.PN, Scer\GAL4^NP6558

Rcom\RT^A.UAS.FRT

adult antennal lobe glomerulus, with Scer\FLP1^ey.PN, Scer\GAL4^amos.PZ

Rcom\RT^A.UAS.FRT

adult antennal lobe glomerulus, with Scer\FLP1^ey.PN, Scer\GAL4^NP6558

Rcom\RT^A.UAS.FRT

adult mushroom body, with Scer\GAL4^ey-OK107

Rcom\RT^A-cs2.UAS

adult mushroom body alpha'-lobe, with Scer\GAL4^ey-OK107

Rcom\RT^A-cs2.UAS

adult olfactory receptor neuron Or47b, with Scer\FLP1^ey.PN, Scer\GAL4^NP6558

Rcom\RT^A.UAS.FRT

adult olfactory receptor neuron Or67d, with Scer\FLP1^ey.PN, Scer\GAL4^NP6558

Rcom\RT^A.UAS.FRT

adult olfactory receptor neuron Or88a, with Scer\FLP1^ey.PN, Scer\GAL4^NP6558

Rcom\RT^A.UAS.FRT

antenna, with Scer\GAL4^Eq

Rcom\RT^A.UAS

antennal lobe glomerulus VA1, with Scer\GAL4^Or47b.7.467

Rcom\RT^A.UAS

antennal lobe glomerulus VA1, with Scer\GAL4^Or88a.PW

Rcom\RT^A.UAS

axon, with Scer\GAL4^15J2

Rcom\RT^A.UAS

axon, with Scer\GAL4^c544

Rcom\RT^A.UAS

axon, with Scer\GAL4^MZ465

Rcom\RT^A.UAS

dMP2 neuron, with Scer\GAL4^s.gcm

Rcom\RT^A.UAS

embryonic/larval ganglionic tracheal branch, with Scer\GAL4^bs-23.26

Rcom\RT^A.UAS

embryonic brain, with Scer\GAL4^how-24B

Rcom\RT^A.UAS

embryonic frontal ganglion, with Scer\GAL4^how-24B

Rcom\RT^A.UAS

embryonic glioblast, with Scer\GAL4^s.gcm

Rcom\RT^A.UAS

embryonic longitudinal glial cell, with Scer\GAL4^C321c

Rcom\RT^A.UAS

embryonic longitudinal glial cell, with Scer\GAL4^ftz.ng

Rcom\RT^A.UAS

embryonic longitudinal glial cell, with Scer\GAL4^s.gcm

Rcom\RT^A.UAS

embryonic somatic muscle cell, with Scer\GAL4^how-24B

Rcom\RT^A-cs2.UAS

endoderm, with Scer\GAL4^miple2.PW

Rcom\RT^A.UAS

endoderm | cell non-autonomous, with Scer\GAL4^bap.3

Rcom\RT^A.UAS

eye, with Scer\GAL4^A4

Rcom\RT^A.UAS

eye, with Scer\GAL4^c311

Rcom\RT^A.UAS

eye, with Scer\GAL4^PDM1

Rcom\RT^A.UAS

eye, with Scer\GAL4^Ugt36A1.PK

Rcom\RT^A.UAS

eye | posterior, with Scer\GAL4^nAChRα6-P2

Rcom\RT^A.UAS

eye | RU486 conditional, with Scer\GAL4^{GMR.in.Switch.PR}

Rcom\RT^A.UAS

eye disc morphogenetic furrow, with Scer\GAL4^c311

Rcom\RT^A.UAS

eye equator, with Scer\GAL4^Eq

Rcom\RT^A.UAS

fascicle, with Scer\GAL4^s.gcm

Rcom\RT^A.UAS

fascicle | embryonic stage, with Scer\GAL4^15J2, Scer\GAL4^s.gcm

Rcom\RT^A.UAS

fascicle | embryonic stage, with Scer\GAL4^s.gcm

Rcom\RT^A.UAS

ganglionic tracheal branch primordium, with Scer\GAL4^C321c

Rcom\RT^A.UAS

ganglionic tracheal branch primordium, with Scer\GAL4^Mz520

Rcom\RT^A.UAS

ganglionic tracheal branch primordium, with Scer\GAL4^Mz820

Rcom\RT^A.UAS

genital disc, with Scer\GAL4^cad-em459

Rcom\RT^A.UAS

genital disc, with Scer\GAL4^tsh-md621

Rcom\RT^A-cs2.UAS

germ band, with Scer\GAL4^how-24B

Rcom\RT^A.UAS

hemocyte, with Scer\GAL4^30A

Rcom\RT^A.UAS

interommatidial bristle

Rcom\RT^A-cs2.sev

interommatidial bristle, with Scer\GAL4^c311

Rcom\RT^A.UAS

larval abdominal intersegmental nerve, with eve^{2xCQ.RC.G4DBD}

Rcom\RT^A.UAS

larval abdominal intersegmental nerve, with Scer\GAL4^eve.RN2

Rcom\RT^A.UAS

larval DA1 motor neuron, with Scer\GAL4^eve.RN2

Rcom\RT^A.UAS

larval DA1 motor neuron, with Scer\GAL4^s.gcm

Rcom\RT^A.UAS

larval glial cell, with Scer\GAL4¹⁵⁸

Rcom\RT^A.UAS

larval glial cell, with Scer\GAL4^s.gcm

Rcom\RT^A.UAS

larval intersegmental nerve, with eve^{2xCQ.RC.G4DBD}

Rcom\RT^A.UAS

larval intersegmental nerve, with Scer\GAL4^eve.RN2

Rcom\RT^A.UAS

larval longitudinal connective, with Scer\GAL4^15J2, Scer\GAL4^s.gcm

Rcom\RT^A.UAS

larval longitudinal connective, with Scer\GAL4¹⁵⁸

Rcom\RT^A.UAS

larval longitudinal connective, with Scer\GAL4^ftz.ng

Rcom\RT^A.UAS

larval longitudinal connective, with Scer\GAL4^Mz520

Rcom\RT^A.UAS

larval longitudinal connective, with Scer\GAL4^s.gcm

Rcom\RT^A.UAS

larval mesothoracic intersegmental nerve, with eve^{2xCQ.RC.G4DBD}

Rcom\RT^A.UAS

larval mesothoracic intersegmental nerve, with Scer\GAL4^eve.RN2

Rcom\RT^A.UAS

larval metathoracic intersegmental nerve, with eve^{2xCQ.RC.G4DBD}

Rcom\RT^A.UAS

larval metathoracic intersegmental nerve, with Scer\GAL4^eve.RN2

Rcom\RT^A.UAS

larval MP1 neuron, with Scer\GAL4^s.gcm

Rcom\RT^A.UAS

larval muscle system, with Scer\GAL4^nau.PM

Rcom\RT^A.UAS

larval neuron, with Scer\GAL4¹⁵⁸

Rcom\RT^A.UAS

larval neuron, with Scer\GAL4^C321c

Rcom\RT^A.UAS

larval neuron, with Scer\GAL4^s.gcm

Rcom\RT^A.UAS

larval prothoracic intersegmental nerve, with eve^{2xCQ.RC.G4DBD}

Rcom\RT^A.UAS

larval prothoracic intersegmental nerve, with Scer\GAL4^eve.RN2

Rcom\RT^A.UAS

larval RP2 motor neuron, with Scer\GAL4^eve.RN2

Rcom\RT^A.UAS

larval RP2 motor neuron | ectopic, with Scer\GAL4^s.gcm

Rcom\RT^A.UAS

larval ventral nerve cord | embryonic stage, with Scer\GAL4^srp.Hemo

Rcom\RT^A.UAS

Rcom\RT^A-cs2.sev

maxillary palp, with Scer\GAL4^Eq

Rcom\RT^A.UAS

mesoderm, with Scer\GAL4^how-24B

Rcom\RT^A.UAS

mesonotum, with Scer\GAL4^Eq

Rcom\RT^A.UAS

mesothoracic tergum & chaeta, with Scer\GAL4^Eq

Rcom\RT^A.UAS

mesothoracic tergum & chaeta, with Scer\GAL4^PDM1

Rcom\RT^A.UAS

neuron & antennal glomerulus, with Scer\GAL4^Mz19

Rcom\RT^A.UAS

neuron & antennal glomerulus DA1, with Scer\GAL4^Mz19

Rcom\RT^A.UAS

neuron & antennal glomerulus VA1, with Scer\GAL4^Mz19

Rcom\RT^A.UAS

olfactory neuron & antennal glomerulus VA1, with Scer\GAL4^Or47b.7.467

Rcom\RT^A.UAS

olfactory neuron & antennal glomerulus VA1, with Scer\GAL4^Or88a.PW

Rcom\RT^A.UAS

ommatidium, with Scer\GAL4^c311

Rcom\RT^A.UAS

ommatidium | RU486 conditional, with Scer\GAL4^{GMR.in.Switch.PR}

Rcom\RT^A.UAS

pCC neuron, with Scer\GAL4^15J2, Scer\GAL4^s.gcm

Rcom\RT^A.UAS

pCC neuron, with Scer\GAL4^s.gcm

Rcom\RT^A.UAS

peripodial epithelium, with Scer\GAL4^c311

Rcom\RT^A.UAS

photoreceptor cell R1

Rcom\RT^A-cs2.sev

photoreceptor cell R2

Rcom\RT^A-cs2.sev

photoreceptor cell R3

Rcom\RT^A-cs2.sev

photoreceptor cell R4

Rcom\RT^A-cs2.sev

photoreceptor cell R5

Rcom\RT^A-cs2.sev

photoreceptor cell R6

Rcom\RT^A-cs2.sev

photoreceptor cell R7

Rcom\RT^A-cs2.sev

photoreceptor cell R8

Rcom\RT^A-cs2.sev

Rcom\RT^A-cs2.sev

symmetrical commissure, with Scer\GAL4^ftz.ng

Rcom\RT^A.UAS

terminalia, with Scer\GAL4^cad-em459

Rcom\RT^A.UAS

tract, with Scer\GAL4^ey-OK107

Rcom\RT^A-cs2.UAS

U neuron | embryonic stage 13, with eve^{2xCQ.RC.G4DBD}

Rcom\RT^A.UAS

ventral oblique muscle cell, with Scer\GAL4^how-24B

Rcom\RT^A-cs2.UAS

visceral trunk mesoderm | cell non-autonomous, with Scer\GAL4^miple2.PW

Rcom\RT^A.UAS

vMP2 neuron, with Scer\GAL4^s.gcm

Rcom\RT^A.UAS

wing, with Scer\GAL4^ap-md544

Rcom\RT^A-cs2.UAS

wing, with Scer\GAL4^bbg-C96

Rcom\RT^A-cs2.UAS

wing, with Scer\GAL4^brk.PU

Rcom\RT^A-cs2.UAS

wing, with Scer\GAL4^ci.PU

Rcom\RT^A-cs2.UAS

wing, with Scer\GAL4^en-e16E

Rcom\RT^A-cs2.UAS

wing disc, with Scer\GAL4^C-734

Rcom\RT^A-cs2.UAS

wing disc, with Scer\GAL4^sd-SG29.1

Rcom\RT^A.UAS

wing disc, with Scer\GAL4^zfh2-MS209

Rcom\RT^A-cs2.UAS

wing disc | cell non-autonomous | larval stage, with Scer\GAL4^ap-md544

Rcom\RT^A-cs2.UAS

wing disc | dorsal, with Scer\GAL4^ap-md544

Rcom\RT^A-cs2.UAS

wing disc posterior compartment, with Scer\GAL4^en-e16E

Rcom\RT^A-cs2.UAS

Orthologs

Downloads

Download All DIOPT Orthologs

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Drosophila melanogaster (Fruit fly) (0)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

Class of Gene

engineered_foreign_gene

Stocks and Reagents

Stocks (6)

28999

w^*; P{UAS-RA}19

29001

w^*; P{PUFWTRA}19

28998

w^*; P{UAS-RA}1.1/CyO

29000

w^*; P{PUFWTRA}1.1/CyO

38623

w¹¹¹⁸; P{UAS-RA.cs2}39

38624

w¹¹¹⁸; P{UAS-RA.cs2}CC

Other Comments

Scer\GAL4 driving the expression of the toxin ricin A is a simple and efficient method of targetted cell ablation. Scer\GAL4 mediated ablation has been used to kill the interface glia that prefigure and then overlie the longitudinal axon tracts of the embryonic nerve cord. Ablation of these cells leads to the misrouting, thinning or elimination of the longitudinal axon tracts, the glial cells are required for the formation of the longitudinal connectives.

(Hidalgo et al., 1995)

A system for temperature induced killing of specific cells is developed using Rcom\RA.

(Moffat et al., 1992)

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (16)

Reported As

Symbol Synonym

RA

(Chen and Chiang, 2012.5.22)

RT

RTA

(Berdnik et al., 2006, Smith et al., 1996)

Rcom\RA

Rcom\RT

Ricin

(Yorozu et al., 2009, Booth et al., 2000)

RicinA

(Hong et al., 2009, Berdnik et al., 2006)

ricin

(Martinek et al., 2008, Kimbrell et al., 2002, Roman and Davis, 2002, Tang and Sun, 2002, Hidalgo et al., 2001, Auld, 1999, Beaufils et al., 1998, John and Brand, 1997)

ricin a

(Duffy, 2002)

ricinA

(Gorfinkiel et al., 2003, Englund et al., 2002, Namba and Minden, 1998)

Name Synonyms

Ricin

(Mesquita et al., 2010, Fox and Spradling, 2009)

Ricin A

(Wolfstetter et al., 2009)

Ricin toxin A-chain

Ricin toxin gene

ricin

(Chen and Chiang, 2012.5.22)

ricin A chain

(Yorozu et al., 2009)

ricin toxin A

(Kamikouchi et al., 2009)

ricin-A

(Bower et al., 2014)

ricinA

(Sanchez-Soriano and Prokop, 2005)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 0 )

References (71)