PVF, VEGF, DmVEGF-1, Vegf17E, Pvf-1
ligands that orchestrate migratory patterns of hemocytes at the embryonic ventral midline - essential cell autonomously for proper positioning of the salivary glands - border cell migration
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.52
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pvf1 using the Feature Mapper tool.
Stron Pvf1 expression was observed in the tracheal cells, caudal ectoderm, Malpighian tubules, and in a posterior ectodermal ring in embryos. Expression is not observed in the ventral midline.
In stage 10 embryos, expression was detected in an ectodermal patch at the caudal margin of the germband where hemocytes enter the tail. This expression continued through stage 12 and subsequently a posterior ring of ectodermal cells expressed transcript. Transcript was also detected in the salivary glands and developing trachea. Salivary gland expression persists through stage 15. General tracheal expression persisted through stage 12. During stage 13 tracheal expression was restricted to the tips of growing ganglionic branches and the visceral branches.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Pvf1 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.