FlyBase Gene Report: Dmel\DCP1

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Gene: Dmel\DCP1

General Information

Symbol

Dmel\DCP1

Species

D. melanogaster

Name

Decapping protein 1

Annotation Symbol

CG11183

Feature Type

protein_coding_gene

FlyBase ID

FBgn0034921

Gene Model Status

Stock Availability

10 publicly available

Gene Summary

Decapping protein 1 (DCP1) encodes a subunit of the mRNA decapping holoenzyme. It is involved in osk mRNA localization and miRNA-mediated gene silencing. [Date last reviewed: 2019-09-19] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Interactive Fly

Also Known As

dDcp1, Dcp-1

Key Links

Genomic Location

Cytogenetic map

Sequence location

2R:23,888,764..23,890,276 [-]

Recombination map

2-105

RefSeq locus

NT_033778 REGION:23888764..23890276

Sequence

Get Decorated FASTA

Genomic Maps

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (17 terms)

Molecular Function (4 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

enables protein binding

inferred from physical interaction with UniProtKB:Q9VVI2

(Tritschler et al., 2007)

inferred from physical interaction with UniProtKB:Q9VKK1

(Jinek et al., 2008)

NOT enables 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity

inferred from direct assay

(Lin et al., 2008)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables enzyme activator activity

inferred from electronic annotation with InterPro:IPR010334

(InterPro Project Members, 2004-)

enables mRNA binding

inferred from biological aspect of ancestor with PANTHER:PTN000418281

(GO Reference Genome Project, 2011-)

Biological Process (8 terms)

Terms Based on Experimental Evidence (7 terms)

CV Term

Evidence

References

involved_in deadenylation-independent decapping of nuclear-transcribed mRNA

inferred from direct assay

(Nishihara et al., 2013)

involved_in miRNA-mediated post-transcriptional gene silencing

inferred from mutant phenotype

(Rehwinkel et al., 2005)

involved_in nuclear-transcribed mRNA catabolic process

inferred from mutant phenotype

(Lin et al., 2006)

involved_in pole plasm oskar mRNA localization

inferred from mutant phenotype

(Lee et al., 2020, Lin et al., 2006)

involved_in positive regulation of mRNA catabolic process

inferred from direct assay

(Nishihara et al., 2013)

involved_in regulation of cytoplasmic mRNA processing body assembly

inferred from mutant phenotype

(Lin et al., 2008)

NOT involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

inferred from mutant phenotype

(Rehwinkel et al., 2005)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in deadenylation-dependent decapping of nuclear-transcribed mRNA

inferred from biological aspect of ancestor with PANTHER:PTN000418281

(GO Reference Genome Project, 2011-)

inferred from electronic annotation with InterPro:IPR010334

(InterPro Project Members, 2004-)

involved_in deadenylation-independent decapping of nuclear-transcribed mRNA

inferred from biological aspect of ancestor with PANTHER:PTN000418281

(GO Reference Genome Project, 2011-)

Cellular Component (5 terms)

Terms Based on Experimental Evidence (5 terms)

CV Term

Evidence

References

is_active_in cytoplasmic stress granule

inferred from direct assay

(Ricolo et al., 2025)

located_in cytoplasm

inferred from direct assay

(Lin et al., 2008)

is_active_in P granule

inferred from direct assay

(Lim et al., 2009)

is_active_in P-body

inferred from direct assay

(Ricolo et al., 2025)

located_in P-body

inferred from direct assay

(Lee et al., 2020, Fan et al., 2011, Eulalio et al., 2007, Liu and Gall, 2007, Lin et al., 2006)

located_in pole plasm

inferred from direct assay

(Lee et al., 2020)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

is_active_in P-body

inferred from biological aspect of ancestor with PANTHER:PTN000418281

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

Protein Family (UniProt)

-

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Decapping protein 1 (DCP1) encodes a subunit of the mRNA decapping holoenzyme. It is involved in osk mRNA localization and miRNA-mediated gene silencing. [Date last reviewed: 2019-09-19]

Gene Model and Products

Number of Transcripts

2

Number of Unique Polypeptides

1

Please see the JBrowse view of Dmel\DCP1 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9W1H5)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

PDB - An information portal to biological macromolecular structures

2LYD
2WX4

Comments on Gene Model

Gene model reviewed during 5.52

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

FBtr0072223

1513

372

FBtr0301648

1225

372

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

FBpp0072132

41.4

372

7.20

FBpp0290862

41.4

372

7.20

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

372 aa isoforms: DCP1-PA, DCP1-PB

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

PDB - An information portal to biological macromolecular structures

2LYD
2WX4

Linkouts

Sequences Consistent with the Gene Model

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\DCP1 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

DCP1_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

1.19

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 16 -- 17

larval somatic muscle cell

(van der Laan et al., 2012)

adult stage | male & spermatogenesis

primary spermatocyte

• P-body

(Zabolotskaya et al., 2008)

• P-body

(Zabolotskaya et al., 2008)

(Lin et al., 2008)

oogenesis stage S2 -- S7

oocyte | posterior

(Lin et al., 2006)

oogenesis stage S3 -- S6

• cytoplasm

(Lin et al., 2006)

oogenesis stage S8

oocyte | anterior

(Lin et al., 2006)

oogenesis stage S9 -- S10

oocyte | posterior

(Lin et al., 2006)

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Dcp1 protein is localized to small cytoplasmic granules, likely corresponding to processing bodies, in muscle cells.

(van der Laan et al., 2012)

DCP1 protein is localized to cytoplasmic foci in spermatogonia and primary spermatocytes. DCP1 is colocalized with pcm and me31B protein in the cytoplasmic foci.

(Zabolotskaya et al., 2008)

DCP1 protein is localized to the posterior pole of the oocyte after oogenesis stage 2 to stage 7. At stage 8, DCP1 transiently accumulates at the anterior pole of the oocyte and forms a ring structure. This pattern is similar to osk and other posteriorly localized components. After stage 9, DCP1 is relocalized at the posterior crescent and is maintained there until at least stage 10B. Punctate staining of DCP1 is observed in nurse cell cytoplasm at early stages where it colocalizes with DCP2.

(Lin et al., 2006)

Marker for

Subcellular Localization

CV Term

Evidence

References

is_active_in cytoplasmic stress granule

inferred from direct assay

(Ricolo et al., 2025)

located_in cytoplasm

inferred from direct assay

(Lin et al., 2008)

is_active_in P granule

inferred from direct assay

(Lim et al., 2009)

is_active_in P-body

inferred from direct assay

(Ricolo et al., 2025)

located_in P-body

inferred from direct assay

(Lee et al., 2020, Fan et al., 2011, Eulalio et al., 2007, Liu and Gall, 2007, Lin et al., 2006)

located_in pole plasm

inferred from direct assay

(Lee et al., 2020)

Expression Deduced from Reporters

Reporter: P{YFP-DCP1.L}

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | male & spermatogenesis

primary spermatocyte

• P-body

(Zabolotskaya et al., 2008)

• P-body

(Zabolotskaya et al., 2008)

oogenesis stage S6

(Lee et al., 2020)

oogenesis stage S10

oocyte | posterior

(Lee et al., 2020)

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\DCP1 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\DCP1

View exonic expression by tissue for Dmel\DCP1

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

37790/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0034921

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0034921

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0034921

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG11183

Flygut - An atlas of the Drosophila adult midgut

FBgn0034921

Images

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 5 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 20 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of DCP1

Transgenic constructs containing regulatory region of DCP1

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

(Ryder, 2004.4.26)

Inferred from location ( 6 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal | embryonic stage | germline clone | maternal effect

DCP1^b53

lethal | recessive

lethal - all die before end of pupal stage | recessive

DCP1^442P

lethal - all die during embryonic stage | maternal effect, with DCP1^b53

DCP1^tT3

lethal - all die during embryonic stage | maternal effect, with DCP1^tT3

DCP1^b53

partially lethal, with Scer\GAL4^tin.CΔ4

DCP1^GD7227

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

DCP1^GD7227

viable, with Scer\GAL4^Mef2.PR

DCP1^GD7227

viable, with Scer\GAL4^pnr-MD237

DCP1^GD7227

Sterility

Allele

female fertile, with Scer\GAL4^{VP16.nanos.UTR}

DCP1^HMS05731

female semi-sterile, with DCP1^b53

DCP1^tT3

female semi-sterile, with DCP1^tT3

DCP1^b53

Other Phenotypes

Allele

abnormal cell migration | embryonic stage, with Scer\GAL4^{VP16.mat.αTub67C}

abnormal pain response | adult stage, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

DCP1^GD7227

chemical resistant, with Scer\GAL4^elav.PU

DCP1^GD7227

short lived | heat sensitive, with Scer\GAL4^tin.CΔ4

DCP1^GD7227

some die during embryonic stage | maternal effect, with DCP1^b53

DCP1^tT3

some die during embryonic stage | maternal effect, with DCP1^tT3

DCP1^b53

some die during pupal stage | recessive

DCP1^442P

Phenotype manifest in

Allele

egg chamber | germline clone

DCP1^442P

embryo | anterior | maternal effect

DCP1^b53

embryonic abdominal segment | maternal effect

DCP1^b53

embryonic abdominal segment | maternal effect, with DCP1^b53

DCP1^tT3

embryonic abdominal segment | maternal effect, with DCP1^tT3

DCP1^b53

P-body, with DCP1^442P

DCP1^tT2.R57A

P-body, with DCP1^tT2.R57A

DCP1^442P

primordial germ cell | embryonic stage, with Scer\GAL4^{VP16.mat.αTub67C}

primordial germ cell | maternal effect, with DCP1^b53

DCP1^tT3

primordial germ cell | maternal effect, with DCP1^tT3

DCP1^b53

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (2)

12 of 14

Yes

Yes

11 of 14

No

Yes

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (2)

11 of 14

Yes

Yes

9 of 14

No

Yes

Mus musculus (laboratory mouse) (2)

10 of 14

Yes

Yes

10 of 14

Yes

Yes

Xenopus tropicalis (Western clawed frog) (5)

9 of 13

Yes

Yes

8 of 13

No

Yes

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

Danio rerio (Zebrafish) (2)

12 of 14

Yes

Yes

9 of 14

No

Yes

Caenorhabditis elegans (Nematode, roundworm) (1)

11 of 14

Yes

Yes

Anopheles gambiae (African malaria mosquito) (1)

Agam\AgaP_AGAP012645

11 of 12

Yes

Yes

Arabidopsis thaliana (thale-cress) (1)

7 of 13

Yes

Yes

Saccharomyces cerevisiae (Brewer's yeast) (1)

2 of 13

Yes

Yes

Schizosaccharomyces pombe (Fission yeast) (1)

6 of 12

Yes

Yes

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:DCP1. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (0)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

DCP1B; decapping mRNA 1B

12 of 14

DCP1A; decapping mRNA 1A

11 of 14

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

static light scattering, x-ray crystallography, predetermined participant, anti tag coimmunoprecipitation, anti tag western blot

(Tritschler et al., 2009)

experimental knowledge based

(Guruharsha et al., 2011)

anti tag coimmunoprecipitation, anti tag western blot

(Braun et al., 2012)

anti tag coimmunoprecipitation, western blot

(Ditzel et al., 2008)

anti tag coimmunoprecipitation, anti tag western blot, western blot

(Zekri et al., 2009, Tritschler et al., 2008, Tritschler et al., 2007)

anti tag coimmunoprecipitation, anti tag western blot, western blot

(Lee et al., 2020, Sgromo et al., 2017, Braun et al., 2012, Jinek et al., 2008)

anti bait coimmunoprecipitation, peptide massfingerprinting

(Habermann et al., 2012)

anti tag coimmunoprecipitation, western blot

(Lin et al., 2006)

proximity ligation assay, fluorescence microscopy

(Ricolo et al., 2025)

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Hurd et al., 2016)

anti bait coimmunoprecipitation, western blot, pull down, molecular weight estimation by staining, anti tag coimmunoprecipitation, anti tag western blot, nuclear magnetic resonance, predetermined participant

(Braun et al., 2012)

anti tag coimmunoprecipitation, anti tag western blot, western blot

(Tritschler et al., 2008)

anti tag coimmunoprecipitation, western blot

(Lin et al., 2006)

RNA-protein

Physical Interaction

Assay

References

anti bait coimmunoprecipitation, primer specific pcr

(Gehrke et al., 2015)

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

enhanceable

(Fan et al., 2011)

suppressible

(Gehrke et al., 2015)

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

63383

DroID - A comprehensive database of gene and protein interactions.

FBgn0034921

MIST (protein-protein) - An integrated Molecular Interaction Database

37790

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

RNA degradation

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

mRNA decay by 5' to 3' exoribonuclease

Class of Gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

2R

Recombination map

2-105

Cytogenetic map

Sequence location

2R:23,888,764..23,890,276 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

60A8-60A8

Limits computationally determined from genome sequence between P{lacW}ken^k11035&P{EP}CG17658^EP730 and P{EP}Tal^EP489&P{EP}CG3065^EP316

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-105

(FlyBase, 2016)

2-109.6

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (10)

Aberrations including deletions of this gene Aberrations including duplications of this gene

17471

y¹ w^67c23; P{EPgy2}DCP1^EY16846/CyO

67874

y¹ sc^* v¹ sev²¹; P{TRiP.HMS05731}attP40

F002735

M{UAS-DCP1.ORF.3xHA.GW}ZH-86Fb

203514

y¹ w^67c23; P{GSV6}DCP1^GS11684/SM1

114473

y^d2 w¹¹¹⁸ P{ey-FLP.N}2; P{neoFRT}42D P{EPgy2}DCP1^EY16846 /CyO y⁺

11183R-1

2RG-0044

y² VhaAC39-1^cho-1 v¹; P{U6-DCP1.NIG.sgRNA}attP40/CyO

v105638

P{KK101204}VIE-260B

v31442

w¹¹¹⁸; P{GD7227}v31442

v342283

P{hsFLP}1, y¹ w¹¹¹⁸; P{HD_CFD01987}attP40/CyO-GFP

Genomic Clones (16)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (69)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

GH04763

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0034921

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0034921

Antibody Information

Laboratory Generated Antibodies

monoclonal

(Miyoshi et al., 2009)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

dsRNA made from templates generated with primers directed against this gene is transfected into S2 cells to study the genes role in decapping.

(Behm-Ansmant et al., 2006)

Dcp1 is required for degradation of osk, bcd and twe mRNAs during embryogenesis.

(Lin et al., 2006)

Dcp1 is required for the posterior localization of osk mRNA in the oocyte.

(Lin et al., 2006)

dsRNA has been made from templates generated with primers directed against this gene.

(Rehwinkel et al., 2005)

In contrast to the decapping enzymes in yeast and humans, the Dcp1 product does not seem to participate in the nonsense-mediated decay pathway.

(Rehwinkel et al., 2005)

Area matching Drosophila EST AI0643375.

(Davies, 2001.3.15)

Relationship to Other Genes

Source for database merge of

Source for merge of: CG11183 anon-WO0118547.163

(FlyBase, 1996-)

Additional comments

Source for merge of CG11183 anon-WO0118547.163 was sequence comparison ( date:051113 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Source for identity of: Dcp1 CG11183

(Lin, 2006.2.28)

Source for identity of: DCP1 Dcp1

(FlyBase, 2009-)

Nomenclature comments

Symbol changed from 'Dcp1' to 'DCP1' to help distinguish this gene from 'Dcp-1' (FBgn0010501).

(FlyBase, 2009-)

Etymology

Synonyms and Secondary IDs (11)

Reported As

Symbol Synonym

CG11183

(National Institute of Genetics Fly Stocks, 2022-, Hurd et al., 2016, Hosono et al., 2015, Murray et al., 2012, Jäger and Dorner, 2010, Müller et al., 2010, Keleman et al., 2009.8.5, Miyoshi et al., 2009, Perkins et al., 2009, Lin et al., 2006, Giot et al., 2003)

Dcp-1

(Nainu et al., 2017, Pressman et al., 2012, Kuranaga, 2011, Navarro et al., 2009, Ditzel et al., 2008)

Dcp1p

(Valencia-Sanchez et al., 2006)

anon-WO0118547.163

dDCP1

(Lim et al., 2009)

dDcp1

(Lee et al., 2020, Gehrke et al., 2015, Fan et al., 2011, Reich et al., 2009, Lin et al., 2008, Lin et al., 2008, Zabolotskaya et al., 2008, Lin, 2006.2.28, Lin et al., 2006, Lin et al., 2006, Seydoux and Braun, 2006, Lin et al., 2004)

dcp-1

(Ojha and Tapadia, 2020, Kang et al., 2017)

dcp1

(Yusuff et al., 2020)

Name Synonyms

Decapping protein 1

(Lin et al., 2008, Lin et al., 2006, Lin et al., 2006)

Secondary FlyBase IDs

FBgn0062201

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 38 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

37790

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9W1H5

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Q9W1H5

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9W1H5

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

37790/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0034921

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0034921

FlyMine - An integrated database for Drosophila genomics

FBgn0034921

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG11183

MARRVEL_MODEL - MARRVEL (model organism gene)

37790

PDB - An information portal to biological macromolecular structures

2LYD
2WX4

Linkouts

BioGRID - A database of protein and genetic interactions.

63383

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0034921

DroID - A comprehensive database of gene and protein interactions.

FBgn0034921

DRSC - Results frm RNAi screens

FBgn0034921

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

DCP1_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0034921

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0034921

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG11183

Flygut - An atlas of the Drosophila adult midgut

FBgn0034921

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0034921

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC012192

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

RNA degradation

MIST (protein-protein) - An integrated Molecular Interaction Database

37790

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

mRNA decay by 5' to 3' exoribonuclease

References (134)