FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\Uvrag
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General Information
Symbol
Dmel\Uvrag
Species
D. melanogaster
Name
UV-resistance associated gene
Annotation Symbol
CG6116
Feature Type
protein_coding_gene
FlyBase ID
FBgn0032499
Gene Model Status
Current
Stock Availability
13 publicly available
Gene Summary
UV-resistance associated gene (Uvrag) encodes a protein that regulates autophagy and vesicle trafficking with the product of Atg6 and class C vacuolar protein sorting complexes. With the products of Atg6 and Pi3K59F, It forms a PI3K(III) complex and plays roles in receptor downregulation and the establishment of proper cell polarity. It is also critical for proper organ rotation during development by controlling receptor endocytosis and subsequent degradation. [Date last reviewed: 2019-03-21] (FlyBase Gene Snapshot)
All Summaries
Key Links
Genomic Location
Cytogenetic map
34B4-34B4
Sequence location
Recombination map
2-48
RefSeq locus
NT_033779 REGION:13286777..13289556
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (12 terms)
Molecular Function (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
enables SNARE binding
inferred from biological aspect of ancestor with PANTHER:PTN000389174
(GO Reference Genome Project, 2011-)
Biological Process (9 terms)
Terms Based on Experimental Evidence (8 terms)
CV Term
Evidence
References
involved_in imaginal disc-derived male genitalia morphogenesis
inferred from mutant phenotype
(Lee et al., 2011)
involved_in negative regulation of cell population proliferation
inferred from mutant phenotype
(Lee et al., 2011)
involved_in negative regulation of Notch signaling pathway
inferred from genetic interaction with FLYBASE:mam; FB:FBgn0002643
(Lee et al., 2011)
inferred from genetic interaction with FLYBASE:N; FB:FBgn0004647
(Lee et al., 2011)
involved_in neuron remodeling
inferred from mutant phenotype
(Issman-Zecharya and Schuldiner, 2014)
involved_in phagocytosis
inferred from mutant phenotype
(Szabó et al., 2023)
involved_in positive regulation of receptor-mediated endocytosis
inferred from mutant phenotype
(Lee et al., 2011)
involved_in protein targeting to lysosome
inferred from mutant phenotype
(Csizmadia et al., 2018)
NOT involved_in autophagosome maturation
inferred from mutant phenotype
(Takáts et al., 2014)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
involved_in SNARE complex assembly
inferred from biological aspect of ancestor with PANTHER:PTN000389174
(GO Reference Genome Project, 2011-)
Cellular Component (2 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
is_active_in endosome
inferred from biological aspect of ancestor with PANTHER:PTN000389174
(GO Reference Genome Project, 2011-)
is_active_in lytic vacuole
inferred from biological aspect of ancestor with PANTHER:PTN000389174
(GO Reference Genome Project, 2011-)
Gene Group (FlyBase)
Pathway (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
    -
    Summaries
    Gene Snapshot
    UV-resistance associated gene (Uvrag) encodes a protein that regulates autophagy and vesicle trafficking with the product of Atg6 and class C vacuolar protein sorting complexes. With the products of Atg6 and Pi3K59F, It forms a PI3K(III) complex and plays roles in receptor downregulation and the establishment of proper cell polarity. It is also critical for proper organ rotation during development by controlling receptor endocytosis and subsequent degradation. [Date last reviewed: 2019-03-21]
    Pathway (FlyBase)
    NEGATIVE REGULATORS OF NOTCH SIGNALING PATHWAY -
    The Notch receptor signaling pathway is activated by the binding of the transmembrane receptor Notch (N) to transmembrane ligands, Dl or Ser, presented on adjacent cells. This results in the proteolytic cleavage of N, releasing the intracellular domain (NICD). NICD translocates into the nucleus, interacting with Su(H) and mam to form a transcription complex, which up-regulates transcription of Notch-responsive genes. Negative regulators of the pathway down-regulate the signal from the sending cell or the response in the receiving cell. (Adapted from FBrf0225731 and FBrf0192604).
    Protein Function (UniProtKB)
    Involved in biosynthetic vesicle transport to lysosomes (PubMed:24554766). Acts as a cell growth regulator (PubMed:21729695). Also has a crucial role in controlling organ rotation by regulating membrane-localized Notch receptor endocytosis and subsequent degradation (PubMed:21729695). Regulation of organ rotation is not by induction of autophagy (PubMed:21729695).
    (UniProt, Q9VK07)
    Summary (Interactive Fly)

    subunit of the PI3K-cIII complex - autophagy - endosomal-lysosomal pathway - axon pruning tumor suppressor - receptor downregulation through endolysosomal degradation - the establishment of proper cell polarity in the developing wing - UV-induced DNA damage repair V

    Gene Model and Products
    Number of Transcripts
    2
    Number of Unique Polypeptides
    2

    Please see the JBrowse view of Dmel\Uvrag for information on other features

    To submit a correction to a gene model please use the Contact FlyBase form

    Protein Domains (via Pfam)
    Isoform displayed:
    Pfam protein domains
    InterPro name
    classification
    start
    end
    Protein Domains (via SMART)
    Isoform displayed:
    SMART protein domains
    InterPro name
    classification
    start
    end
    Structure
    Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9VK07)

    If you don't see a structure in the viewer, refresh your browser.
    Model Confidence:
    • Very high (pLDDT > 90)
    • Confident (90 > pLDDT > 70)
    • Low (70 > pLDDT > 50)
    • Very low (pLDDT < 50)

    AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

    Experimentally Determined Structures
    Crossreferences
    Comments on Gene Model

    Low-frequency RNA-Seq exon junction(s) not annotated.

    Gene model reviewed during 5.47

    Transcript Data
    Annotated Transcripts
    Name
    FlyBase ID
    RefSeq ID
    Length (nt)
    Assoc. CDS (aa)
    Uvrag-RA
    FBtr0080460
    NM_135788
    2520
    696
    Uvrag-RB
    FBtr0334865
    NM_001273512
    2465
    695
    Additional Transcript Data and Comments
    Reported size (kB)
    Comments
    External Data
    Crossreferences
    Polypeptide Data
    Annotated Polypeptides
    Name
    FlyBase ID
    Predicted MW (kDa)
    Length (aa)
    Theoretical pI
    UniProt
    RefSeq ID
    GenBank
    Uvrag-PA
    FBpp0080039
    80.7
    696
    8.69
    Q9VK07
    NP_609632
    AAF53277
    Uvrag-PB
    FBpp0306888
    80.5
    695
    8.60
    M9PD33
    NP_001260441
    AGB92976
    Polypeptides with Identical Sequences

    None of the polypeptides share 100% sequence identity.

    Additional Polypeptide Data and Comments
    Reported size (kDa)
    Comments
    External Data
    Crossreferences
    Linkouts
    Sequences Consistent with the Gene Model
    Mapped Features

    Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Uvrag using the Feature Mapper tool.

    External Data
    Crossreferences
    Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
    Linkouts
    Expression Data
    Testis-specificity index

    The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

    0.44

    Transcript Expression
    Polypeptide Expression
    Additional Descriptive Data
    Marker for
     
    Subcellular Localization
    CV Term
    Evidence
    References
    Expression Deduced from Reporters
    High-Throughput Expression Data
    Associated Tools

    JBrowse - Visual display of RNA-Seq signals

    View Dmel\Uvrag in JBrowse
    RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
    Bulk Downloads
    RNA-Seq RPKM values for all genes
    Reference
    See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
    Developmental Proteome: Life Cycle
    Developmental Proteome: Embryogenesis
    External Data and Images
    Linkouts
    BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
    DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
    EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
    FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
    FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
    Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
    Flygut - An atlas of the Drosophila adult midgut
    Images
    FlyExpress - Embryonic expression images (BDGP data)
    • Stages(s) 1-3
    • Stages(s) 4-6
    • Stages(s) 7-8
    • Stages(s) 9-10
    • Stages(s) 11-12
    • Stages(s) 13-16
    FlyBase Wiki
    Image Based Resources
    Alleles, Insertions, Transgenic Constructs, and Aberrations
    Classical and Insertion Alleles ( 9 )
    For All Classical and Insertion Alleles Show
     
    Other relevant insertions
    Transgenic Constructs ( 15 )
    For All Alleles Carried on Transgenic Constructs Show
    Transgenic constructs containing/affecting coding region of Uvrag
    Transgenic constructs containing regulatory region of Uvrag
    Aberrations (Deficiencies and Duplications) ( 2 )
    Inferred from experimentation ( 2 )
    Gene disrupted in
    Df(2L)ED784
    (Lee et al., 2011)
    Gene partially disrupted in
    Df(2L)CRIMIC-CR70760
    (Gene Disruption Project members, 2018-)
    Inferred from location ( 5 )
    Variants
    Variant Molecular Consequences
    Alleles Representing Disease-Implicated Variants
    Phenotypes
    For more details about a specific phenotype click on the relevant allele symbol.
    Lethality
    Allele
    lethal - all die before end of larval stage (with Df(2L)ED784)
    lethal - all die before end of larval stage (with UvragB21)
    lethal - all die before end of larval stage (with UvragLL03097)
    lethal - all die before end of larval stage | male limited
    lethal - all die before end of larval stage | recessive
    lethal - all die before end of P-stage
    lethal - all die before end of P-stage | recessive
    viable
    Other Phenotypes
    Allele
    abnormal cell shape | adult stage, with Scer\GAL4NP5130
    abnormal eye color | somatic clone
    abnormal immune response, with Scer\GAL4NP5130
    abnormal neuroanatomy | adult stage, with Scer\GAL4GMR71G10, Spyo\Cas9UAS.Tag:NLS(Unk)
    abnormal neuroanatomy | adult stage | somatic clone
    abnormal neuroanatomy | pupal stage | somatic clone
    abnormal size | adult stage, with Scer\GAL4NP5130
    abnormal wound healing | adult stage, with Scer\GAL4repo
    increased cell number | adult stage, with Scer\GAL4NP5130
    increased cell number | adult stage | somatic clone
    increased cell number | somatic clone
    increased cell size | adult stage, with Scer\GAL4NP5130
    increased occurrence of cell division | adult stage, with Scer\GAL4NP5130
    short lived, with Scer\GAL4NP5130
    some die during larval stage (with Df(2L)ED784)
    some die during larval stage | recessive
    Phenotype manifest in
    Allele
    adult marginal nerve wrapping glial cell, with Scer\GAL4repo
    adult midgut epithelium, with Scer\GAL4NP5130
    adult midgut epithelium | somatic clone
    autolysosome | cell autonomous | somatic clone | third instar larval stage, with Scer\GAL4Act.PU
    autolysosome | wandering third instar larval stage | nutrition conditional
    autophagosome | larval stage, with Scer\GAL4Act.PU
    axon | adult stage
    axon | adult stage, with Scer\GAL4GMR71G10, Spyo\Cas9UAS.Tag:NLS(Unk)
    embryonic/larval fat body | wandering third instar larval stage | nutrition conditional
    endosome | adult stage, with Scer\GAL4NP5130
    enteroblast of posterior adult midgut epithelium, with Scer\GAL4NP5130
    enterocyte of posterior adult midgut epithelium, with Scer\GAL4NP5130
    eye | somatic clone
    follicle cell | somatic clone
    gamma Kenyon cell | adult stage, with Scer\GAL4GMR71G10, Spyo\Cas9UAS.Tag:NLS(Unk)
    gamma Kenyon cell | adult stage | somatic clone
    gamma Kenyon cell | pupal stage | somatic clone
    intestinal stem cell of posterior adult midgut epithelium, with Scer\GAL4NP5130
    intracellular vesicle | adult stage, with Scer\GAL4NP5130
    larval fat cell of larval fat body | cell autonomous | somatic clone | third instar larval stage, with Scer\GAL4Act.PU
    late endosome | cell autonomous | somatic clone | third instar larval stage, with Scer\GAL4Act.PU
    lysosome | cell autonomous | somatic clone | third instar larval stage, with Scer\GAL4Act.PU
    major mitochondrial derivative, with Scer\GAL4VP16.nanos.UTR, Scer\GAL4VP16.otu, Scer\GAL4nanos.PG
    male genitalia
    male genitalia, with Scer\GAL4Abd-B-LDN
    male genitalia (with UvragB7)
    male genitalia (with UvragB21)
    male genitalia (with UvragKG04163)
    marginal nerve, with Scer\GAL4repo
    mitochondrial derivative | fertilized egg stage, with Scer\GAL4VP16.mat.αTub67C
    Orthologs
    Downloads
    Download All DIOPT Orthologs
    Human Orthologs (via DIOPT v9.1)
    Species\Gene Symbol
    Score
    Best Score
    Best Reverse Score
    Source
    Compara
    Domainoid
    eggNOG
    Hieranoid
    Homologene
    Inparanoid
    OMA
    OrthoDB
    OrthoFinder
    OrthoInspector
    orthoMCL
    Panther
    Phylome
    SonicParanoid
    Alignment
    Complementation?
    Transgene?
    Homo sapiens (Human) (1)
    Hsap\UVRAG
    11 of 14
    Yes
    Yes
    Model Organism Orthologs (via DIOPT v9.1)
    Species\Gene Symbol
    Score
    Best Score
    Best Reverse Score
    Source
    Compara
    Domainoid
    eggNOG
    Hieranoid
    Homologene
    Inparanoid
    OMA
    OrthoDB
    OrthoFinder
    OrthoInspector
    orthoMCL
    Panther
    Phylome
    SonicParanoid
    Alignment
    Complementation?
    Transgene?
    Rattus norvegicus (Norway rat) (1)
    Rnor\Uvrag
    11 of 14
    Yes
    Yes
    Mus musculus (laboratory mouse) (1)
    Mmus\Uvrag
    9 of 14
    Yes
    Yes
    Xenopus tropicalis (Western clawed frog) (2)
    Xtro\uvrag
    8 of 13
    Yes
    Yes
    Xtro\cldn19
    1 of 13
    No
    Yes
    Danio rerio (Zebrafish) (1)
    Drer\uvrag
    9 of 14
    Yes
    Yes
    Caenorhabditis elegans (Nematode, roundworm) (2)
    Cele\Y34B4A.2
    4 of 14
    Yes
    Yes
    Cele\T23G11.7
    3 of 14
    No
    Yes
    Anopheles gambiae (African malaria mosquito) (1)
    Agam\AgaP_AGAP007772
    12 of 12
    Yes
    Yes
    Arabidopsis thaliana (thale-cress) (2)
    Atha\AT2G32760
    1 of 13
    Yes
    Yes
    Atha\AT2G45990
    1 of 13
    Yes
    Yes
    Saccharomyces cerevisiae (Brewer's yeast) (1)
    Scer\VPS38
    1 of 13
    Yes
    Yes
    Schizosaccharomyces pombe (Fission yeast) (1)
    Spom\atg14
    8 of 12
    Yes
    Yes
    Escherichia coli (enterobacterium) (0)
    Other Organism Orthologs (via OrthoDB)
    Data provided directly from OrthoDB:Uvrag. Refer to their site for version information.
    Paralogs
    Downloads
    Download All DIOPT Paralogs
    Paralogs (via DIOPT v9.1)
    Human Disease Associations
    FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 3 )
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 1 )
    Allele
    Disease
    Interaction
    References
    UvragHMS01357
    model of  colorectal cancer
    is ameliorated by bskDN.UAS.cUa
    (Nagy et al., 2016)
    is ameliorated by Stat92EJF01265
    (Nagy et al., 2016)
    is ameliorated by Stat92EHJ
    (Nagy et al., 2016)
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    UVRAG; UV radiation resistance associated
    11 of 14
    602493
        Functional Complementation Data
        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
        Interactions
        Summary of Physical Interactions
        Interaction Browsers
        View in FlyBase Interactions Browser   View in MIST tool (external link)
        Please see the Physical Interaction reports below for full details
        protein-protein
        Physical Interaction
        Assay
        References
        Uvrag - Miga
        anti tag coimmunoprecipitation, anti tag western blot
        (Xu et al., 2022)
        Uvrag - Rab5
        pull down, peptide massfingerprinting
        (Gillingham et al., 2014)
        Summary of Genetic Interactions
        Interaction Browsers
        View in FlyBase Interactions Browser   View in MIST tool (external link)
        Please look at the allele data for full details of the genetic interactions
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        Uvrag
        suppressible
        Atg5
        (Nagy et al., 2016)
        Uvrag
        suppressible
        Atg14
        (Nagy et al., 2016)
        Uvrag
        suppressible
        bsk
        (Nagy et al., 2016)
        Uvrag
        suppressible
        mam
        (Lee et al., 2011)
        Uvrag
        suppressible
        N
        (Lee et al., 2011)
        Uvrag
        suppressible
        pan
        (Nagy et al., 2016)
        Uvrag
        enhanceable
        ptc
        (Issman-Zecharya and Schuldiner, 2014)
        Uvrag
        suppressible
        Stat92E
        (Nagy et al., 2016)
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        External Data
        Linkouts
        DroID - A comprehensive database of gene and protein interactions.
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Pathways
        Signaling Pathways (FlyBase)
        Metabolic Pathways
        FlyBase
        External Links
        External Data
        Linkouts
        KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
        Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
        Class of Gene
        Genomic Location and Detailed Mapping Data
        Chromosome (arm)
        2L
        Recombination map
        2-48
        Cytogenetic map
        34B4-34B4
        Sequence location
        FlyBase Computed Cytological Location
        Cytogenetic map
        Evidence for location
        34B4-34B4
        Limits computationally determined from genome sequence between P{EP}EP850&P{lacW}l(2)k05911k05911 and P{lacW}l(2)k07914k07914&P{lacW}Nnp-1k07826
        Experimentally Determined Cytological Location
        Cytogenetic map
        Notes
        References
        Experimentally Determined Recombination Data
        Location

        2-48

        (FlyBase, 2016)

        2-43.7

        (Comeron et al., 2012)
        Left of (cM)
        Right of (cM)
        Notes
        Stocks and Reagents
        Stocks (13)
        Genomic Clones (10)
         

        Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

        cDNA Clones (37)
         

        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

        cDNA clones, fully sequenced
        BDGP DGC clones
        Other clones
        Drosophila Genomics Resource Center cDNA clones

        For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        RNAi and Array Information
        Linkouts
        DRSC - Results frm RNAi screens
        Antibody Information
        Laboratory Generated Antibodies
         

        polyclonal

        (Lee et al., 2011)
        Commercially Available Antibodies
         
        Cell Line Information
        Publicly Available Cell Lines
         
          Other Stable Cell Lines
           
            Other Comments

            Uvrag is required for the normal clearance of the paternal mitochondrial derivatives in developing embryos.

            (Politi et al., 2014)
            Relationship to Other Genes
            Source for database merge of
            Additional comments
            Nomenclature History
            Source for database identify of

            Source for identity of: Uvrag CG6116

            (Lee et al., 2011)
            Nomenclature comments
            Etymology
            Synonyms and Secondary IDs (10)
            Datasets (0)
            Study focus (0)
            Experimental Role
            Project
            Project Type
            Title
            Study result (0)
            Result
            Result Type
            Title
            External Crossreferences and Linkouts ( 40 )
            Sequence Crossreferences
            NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
            GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
            GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
            RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
            UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
            UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
            UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
            Other crossreferences
            AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
            BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
            DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
            EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
            FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
            FlyMine - An integrated database for Drosophila genomics
            KEGG Genes - Molecular building blocks of life in the genomic space.
            MARRVEL_MODEL - MARRVEL (model organism gene)
            Linkouts
            Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
            DroID - A comprehensive database of gene and protein interactions.
            DRSC - Results frm RNAi screens
            Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
            FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
            FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
            Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
            Flygut - An atlas of the Drosophila adult midgut
            FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.
            iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
            Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
            KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
            MIST (protein-protein) - An integrated Molecular Interaction Database
            Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
            References (58)