FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\nxf2
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General Information
Symbol
Dmel\nxf2
Species
D. melanogaster
Name
nuclear RNA export factor 2
Annotation Symbol
CG4118
Feature Type
protein_coding_gene
FlyBase ID
FBgn0036640
Gene Model Status
Current
Stock Availability
9 publicly available
Gene Summary
May be involved in the export of mRNA from the nucleus to the cytoplasm (PubMed:11780633). In the ovaries, forms a complex with nxf2, piwi and Nxt1 which acts as effectors of cotranscriptional transposon silencing (PubMed:31219034, PubMed:31368590, PubMed:31384064, PubMed:31570835). On recruitment to a target transcript, interacts with single stranded RNA, thereby anchoring the complex via the nascent target transcript to chromatin and allowing Panx to recruit silencing effectors to establishing repressive heterochromatin at transposon loci (PubMed:31368590, PubMed:31384064, PubMed:31570835). Does not affect piRNA biogenesis (PubMed:31384064). The interaction with Panx stabilizes the nuclear protein complex (PubMed:31384064). Does not bind nucleoporins, but regulates sbr/Nxf1 binding to nucleoporins and, indirectly, transposon exports (PubMed:31384064, PubMed:31570835). (UniProt, Q9VV73)
Contribute a Gene Snapshot for this gene.
All Summaries
Key Links
Genomic Location
Cytogenetic map
73A9-73A9
Sequence location
Recombination map
3-44
RefSeq locus
NT_037436 REGION:16576859..16580306
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (13 terms)
Molecular Function (4 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
enables chromatin-protein adaptor activity
inferred from direct assay
(Iwasaki et al., 2021)
enables protein binding
inferred from physical interaction with UniProtKB:Q9U1H9
(Zhao et al., 2019)
inferred from physical interaction with UniProtKB:Q9V3H8,UniProtKB:Q9VKM1,UniProtKB:Q9W2H9
(Batki et al., 2019, Murano et al., 2019)
inferred from physical interaction with UniProtKB:Q9V3H8,UniProtKB:Q9W2H9
(Fabry et al., 2019)
inferred from physical interaction with UniProtKB:Q9W2H9
(Fabry et al., 2019)
enables single-stranded RNA binding
inferred from direct assay
(Batki et al., 2019, Murano et al., 2019)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
enables RNA binding
inferred from biological aspect of ancestor with PANTHER:PTN000070434
(GO Reference Genome Project, 2011-)
Biological Process (4 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
involved_in protein localization to nuclear periphery
inferred from mutant phenotype
(Iwasaki et al., 2021)
involved_in transposable element silencing by piRNA-mediated heterochromatin formation
inferred from mutant phenotype
(Batki et al., 2019, Fabry et al., 2019, Murano et al., 2019, Zhao et al., 2019)
inferred from mutant phenotype
(Eastwood et al., 2021, Iwasaki et al., 2021)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
involved_in mRNA transport
inferred from electronic annotation with InterPro:IPR005637
(InterPro Project Members, 2004-)
involved_in poly(A)+ mRNA export from nucleus
inferred from biological aspect of ancestor with PANTHER:PTN000070434
(GO Reference Genome Project, 2011-)
Cellular Component (5 terms)
Terms Based on Experimental Evidence (5 terms)
CV Term
Evidence
References
located_in cytoplasm
inferred from direct assay
(Herold et al., 2001)
located_in nucleoplasm
inferred from direct assay
(Herold et al., 2001)
is_active_in nucleus
inferred from direct assay
(Eastwood et al., 2021)
located_in nucleus
inferred from direct assay
(Batki et al., 2019, Fabry et al., 2019, Murano et al., 2019)
part_of RNA polymerase II transcription repressor complex
(Eastwood et al., 2021)
part_of transcription repressor complex
inferred from direct assay
(Fabry et al., 2019, Murano et al., 2019, Zhao et al., 2019)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
is_active_in nucleus
inferred from biological aspect of ancestor with PANTHER:PTN000070434
(GO Reference Genome Project, 2011-)
located_in nucleus
inferred from electronic annotation with InterPro:IPR005637
(InterPro Project Members, 2004-)
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the NXF family. (Q9VV73)
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
PANORAMIX-INDUCED CO-TRANSCRIPTIONAL SILENCING COMPLEX -
The Panoramix-induced co-transcriptional silencing (PICTS) complex is a nuclear complex required for the formation of heterochromatin in piRNA-mediated silencing of transposable elements. (Adapted from FBrf0248008.)
Protein Function (UniProtKB)
May be involved in the export of mRNA from the nucleus to the cytoplasm (PubMed:11780633). In the ovaries, forms a complex with nxf2, piwi and Nxt1 which acts as effectors of cotranscriptional transposon silencing (PubMed:31219034, PubMed:31368590, PubMed:31384064, PubMed:31570835). On recruitment to a target transcript, interacts with single stranded RNA, thereby anchoring the complex via the nascent target transcript to chromatin and allowing Panx to recruit silencing effectors to establishing repressive heterochromatin at transposon loci (PubMed:31368590, PubMed:31384064, PubMed:31570835). Does not affect piRNA biogenesis (PubMed:31384064). The interaction with Panx stabilizes the nuclear protein complex (PubMed:31384064). Does not bind nucleoporins, but regulates sbr/Nxf1 binding to nucleoporins and, indirectly, transposon exports (PubMed:31384064, PubMed:31570835).
(UniProt, Q9VV73)
Gene Model and Products
Number of Transcripts
3
Number of Unique Polypeptides
2

Please see the JBrowse view of Dmel\nxf2 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9VV73)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
PDB - An information portal to biological macromolecular structures
Comments on Gene Model

Gene model reviewed during 5.44

Gene model reviewed during 5.45

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.55

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
nxf2-RA
FBtr0089478
NM_079387
2863
841
nxf2-RB
FBtr0089479
NM_168674
2771
841
nxf2-RC
FBtr0331561
NM_001275024
2723
825
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
nxf2-PA
FBpp0088483
96.6
841
7.41
Q9VV73
NP_524111
AAF49448
nxf2-PB
FBpp0088484
96.6
841
7.41
Q9VV73
NP_730179
AAF49447
nxf2-PC
FBpp0303951
94.7
825
7.52
M9PI81
NP_001261953
AGB94646
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

841 aa isoforms: nxf2-PA, nxf2-PB
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Subunit Structure (UniProtKB)

In the ovaries, part of a complex composed of at least Panx, nxf2, piwi and Nxt1 (PubMed:31219034, PubMed:31368590, PubMed:31384064, PubMed:31570835). The complex is knowns as Panx-induced cotranscriptional silencing (PICTS) complex, Panx-nxf2-dependent TAP/p15 silencing (Pandas complex), SFiNX (silencing factor interacting nuclear export variant) or piwi-Panx-nxf2-p15 (PPNP) complex (PubMed:31219034, PubMed:31368590, PubMed:31384064, PubMed:31570835). Interacts (via TAP-C domain) with Panx (via NIR region); the interaction is direct (PubMed:31219034, PubMed:31368590, PubMed:31570835). Interacts (via NTF2 domain) with Nxt1; the interaction is direct and prevents Nxt1 binding to nucleoporins (PubMed:31368590). Interacts with sbr/Nxf1 (PubMed:31570835).

(UniProt, Q9VV73)
Domain

The RNA-binding domain is a non-canonical RNP-type domain.

The TAP-C domain (also known as UBA domain) mediates the interaction with Panx.

(UniProt, Q9VV73)
Crossreferences
InterPro - A database of protein families, domains and functional sites
PDB - An information portal to biological macromolecular structures
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\nxf2 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

0.03

Transcript Expression
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in cytoplasm
inferred from direct assay
(Herold et al., 2001)
located_in nucleoplasm
inferred from direct assay
(Herold et al., 2001)
is_active_in nucleus
inferred from direct assay
(Eastwood et al., 2021)
located_in nucleus
inferred from direct assay
(Batki et al., 2019, Fabry et al., 2019, Murano et al., 2019)
part_of RNA polymerase II transcription repressor complex
(Eastwood et al., 2021)
part_of transcription repressor complex
inferred from direct assay
(Fabry et al., 2019, Murano et al., 2019, Zhao et al., 2019)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\nxf2 in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 8 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 16 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of nxf2
Transgenic constructs containing regulatory region of nxf2
Aberrations (Deficiencies and Duplications) ( 0 )
Inferred from experimentation ( 0 )
Inferred from location ( 7 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (6)
Hsap\NXF3
6 of 14
Yes
No
1  
Hsap\NXF1
5 of 14
No
No
Hsap\NXF2B
5 of 14
No
No
Hsap\NXF2
5 of 14
No
No
Hsap\NXF5
4 of 14
No
No
2  
Hsap\DNAAF11
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (5)
Rnor\Nxf1
6 of 14
Yes
No
Rnor\Nxf2
6 of 14
Yes
No
Rnor\Nxf3
6 of 14
Yes
No
Rnor\Nxf7
6 of 14
Yes
No
Rnor\Nxf5
1 of 14
No
Yes
Mus musculus (laboratory mouse) (4)
Mmus\Nxf2
6 of 14
Yes
No
Mmus\Nxf3
6 of 14
Yes
No
Mmus\Nxf7
6 of 14
Yes
No
Mmus\Nxf1
5 of 14
No
No
Xenopus tropicalis (Western clawed frog) (3)
Xtro\LOC100490733
4 of 13
Yes
No
Xtro\nxf1
3 of 13
No
No
Xtro\churc1
1 of 13
No
Yes
Danio rerio (Zebrafish) (2)
Drer\nxf1a
6 of 14
Yes
No
Drer\nxf1b
6 of 14
Yes
No
Caenorhabditis elegans (Nematode, roundworm) (2)
Cele\nxf-2
6 of 14
Yes
No
Cele\nxf-1
5 of 14
No
No
Anopheles gambiae (African malaria mosquito) (4)
Agam\AgaP_AGAP002004
11 of 12
Yes
Yes
Agam\AgaP_AGAP002193
5 of 12
No
No
Agam\AgaP_AGAP002336
1 of 12
No
No
Agam\AgaP_AGAP005606
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (0)
Saccharomyces cerevisiae (Brewer's yeast) (1)
Scer\MEX67
5 of 13
Yes
No
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\mex67
4 of 12
Yes
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:nxf2. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (4)
sbr
6 of 13
Nxf3
5 of 13
nxf4
3 of 13
ssp2
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    NXF3; nuclear RNA export factor 3
    6 of 14
    300316
         
        NXF1; nuclear RNA export factor 1
        5 of 14
        602647
            NXF2B; nuclear RNA export factor 2B
            5 of 14
                NXF2; nuclear RNA export factor 2
                5 of 14
                300315
                    NXF5; nuclear RNA export factor 5
                    4 of 14
                    300319
                         
                        Functional Complementation Data
                        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                        Interactions
                        Summary of Physical Interactions
                        Interaction Browsers
                        View in FlyBase Interactions Browser   View in MIST tool (external link)
                        Please see the Physical Interaction reports below for full details
                        protein-protein
                        Physical Interaction
                        Assay
                        References
                        nxf2
                        anti tag coimmunoprecipitation, anti tag western blot
                        (Eastwood et al., 2021)
                        nxf2 - Cen
                        experimental knowledge based
                        (Guruharsha et al., 2011)
                        nxf2 - Fgop2
                        experimental knowledge based
                        (Guruharsha et al., 2011)
                        nxf2 - Lam
                        anti bait coimmunoprecipitation, western blot
                        (Iwasaki et al., 2021)
                        nxf2 - Nxt1
                        cross-linking study, Identification by mass spectrometry, anti tag coimmunoprecipitation, western blot, anti tag western blot, chromatography technology, molecular weight estimation by staining, molecular sieving, two hybrid, three hybrid
                        (Batki et al., 2019, ElMaghraby et al., 2019, Fabry et al., 2019, Murano et al., 2019, Zhao et al., 2019)
                        nxf2 - Panx
                        coimmunoprecipitation, western blot, cross-linking study, x-ray crystallography, three hybrid, chromatography technology, molecular weight estimation by staining, two hybrid, anti bait coimmunoprecipitation, Identification by mass spectrometry, anti tag coimmunoprecipitation, isothermal titration calorimetry, predetermined participant, pull down, anti tag western blot, molecular sieving, experimental knowledge based
                        (Schnabl et al., 2021, Batki et al., 2019, Fabry et al., 2019, Murano et al., 2019, Zhao et al., 2019, Guruharsha et al., 2011)
                        nxf2 - RluA-2
                        experimental knowledge based
                        (Guruharsha et al., 2011)
                        nxf2 - Slmap
                        experimental knowledge based
                        (Guruharsha et al., 2011)
                        nxf2 - Tlk
                        experimental knowledge based
                        (Guruharsha et al., 2011)
                        nxf2 - Ubqn
                        experimental knowledge based
                        (Guruharsha et al., 2011)
                        nxf2 - ana2
                        experimental knowledge based
                        (Guruharsha et al., 2011)
                        nxf2 - cmet
                        experimental knowledge based
                        (Guruharsha et al., 2011)
                        nxf2 - ctp
                        anti tag coimmunoprecipitation, anti tag western blot, western blot, Identification by mass spectrometry
                        (Eastwood et al., 2021, Schnabl et al., 2021)
                        nxf2 - dup
                        experimental knowledge based
                        (Guruharsha et al., 2011)
                        nxf2 - geminin
                        experimental knowledge based
                        (Guruharsha et al., 2011)
                        nxf2 - mael
                        anti tag coimmunoprecipitation, western blot
                        (Murano et al., 2019)
                        nxf2 - piwi
                        anti tag coimmunoprecipitation, western blot, Identification by mass spectrometry, anti bait coimmunoprecipitation
                        (Fabry et al., 2019, Murano et al., 2019)
                        nxf2 - row
                        experimental knowledge based
                        (Guruharsha et al., 2011)
                        nxf2 - sbr
                        pull down, molecular weight estimation by staining, anti tag coimmunoprecipitation, western blot, cross-linking study, Identification by mass spectrometry, split luciferase complementation, luminiscence technology
                        (Zhao et al., 2019)
                        nxf2 - woc
                        experimental knowledge based
                        (Guruharsha et al., 2011)
                        Summary of Genetic Interactions
                        Interaction Browsers
                        Starting gene(s)
                        Interaction type
                        Interacting gene(s)
                        Reference
                        Starting gene(s)
                        Interaction type
                        Interacting gene(s)
                        Reference
                        External Data
                        Subunit Structure (UniProtKB)
                        In the ovaries, part of a complex composed of at least Panx, nxf2, piwi and Nxt1 (PubMed:31219034, PubMed:31368590, PubMed:31384064, PubMed:31570835). The complex is knowns as Panx-induced cotranscriptional silencing (PICTS) complex, Panx-nxf2-dependent TAP/p15 silencing (Pandas complex), SFiNX (silencing factor interacting nuclear export variant) or piwi-Panx-nxf2-p15 (PPNP) complex (PubMed:31219034, PubMed:31368590, PubMed:31384064, PubMed:31570835). Interacts (via TAP-C domain) with Panx (via NIR region); the interaction is direct (PubMed:31219034, PubMed:31368590, PubMed:31570835). Interacts (via NTF2 domain) with Nxt1; the interaction is direct and prevents Nxt1 binding to nucleoporins (PubMed:31368590). Interacts with sbr/Nxf1 (PubMed:31570835).
                        (UniProt, Q9VV73 )
                        Linkouts
                        DroID - A comprehensive database of gene and protein interactions.
                        MIST (protein-protein) - An integrated Molecular Interaction Database
                        Pathways
                        Signaling Pathways (FlyBase)
                        Metabolic Pathways
                        FlyBase
                        External Links
                        External Data
                        Linkouts
                        Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                        Class of Gene
                        Genomic Location and Detailed Mapping Data
                        Chromosome (arm)
                        3L
                        Recombination map
                        3-44
                        Cytogenetic map
                        73A9-73A9
                        Sequence location
                        FlyBase Computed Cytological Location
                        Cytogenetic map
                        Evidence for location
                        73A9-73A9
                        Limits computationally determined from genome sequence between P{lacW}l(3)j10E8j10E8&P{PZ}l(3)1053210532 and P{PZ}Baldspot02281
                        Experimentally Determined Cytological Location
                        Cytogenetic map
                        Notes
                        References
                        Experimentally Determined Recombination Data
                        Location

                        3-44

                        (FlyBase, 2016)

                        3-39.2

                        (Comeron et al., 2012)
                        Left of (cM)
                        Right of (cM)
                        Notes
                        Stocks and Reagents
                        Stocks (9)
                        Genomic Clones (13)
                         

                        Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

                        cDNA Clones (72)
                         

                        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

                        cDNA clones, fully sequenced
                        BDGP DGC clones
                        Other clones
                          Drosophila Genomics Resource Center cDNA clones

                          For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                          cDNA Clones, End Sequenced (ESTs)
                          BDGP DGC clones
                          Other clones
                          RNAi and Array Information
                          Linkouts
                          DRSC - Results frm RNAi screens
                          Antibody Information
                          Laboratory Generated Antibodies
                           

                          monoclonal

                          (Batki et al., 2019, Murano et al., 2019)

                          polyclonal

                          (Zhao et al., 2019)
                          Commercially Available Antibodies
                           
                          Cell Line Information
                          Publicly Available Cell Lines
                           
                            Other Stable Cell Lines
                             
                              Other Comments
                              Relationship to Other Genes
                              Source for database merge of
                              Additional comments

                              Source for identity of nxf2 CG4118 was sequence comparison ( date:010702 ).

                              (FlyBase, 1996-)
                              Nomenclature History
                              Source for database identify of

                              Source for identity of: nxf2 CG4118

                              (FlyBase, 1996-)
                              Nomenclature comments
                              Etymology
                              Synonyms and Secondary IDs (6)
                              Datasets (0)
                              Study focus (0)
                              Experimental Role
                              Project
                              Project Type
                              Title
                              Study result (0)
                              Result
                              Result Type
                              Title
                              External Crossreferences and Linkouts ( 51 )
                              Sequence Crossreferences
                              NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                              GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                              GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                              RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                              UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
                              UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
                              UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
                              Other crossreferences
                              AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
                              BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
                              DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
                              EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
                              FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
                              FlyMine - An integrated database for Drosophila genomics
                              InterPro - A database of protein families, domains and functional sites
                              KEGG Genes - Molecular building blocks of life in the genomic space.
                              MARRVEL_MODEL - MARRVEL (model organism gene)
                              PDB - An information portal to biological macromolecular structures
                              Linkouts
                              Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                              DroID - A comprehensive database of gene and protein interactions.
                              DRSC - Results frm RNAi screens
                              Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                              FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                              FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                              Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                              Flygut - An atlas of the Drosophila adult midgut
                              FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.
                              MIST (protein-protein) - An integrated Molecular Interaction Database
                              Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                              References (57)