FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\pico
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General Information
Symbol
Dmel\pico
Species
D. melanogaster
Name
pico
Annotation Symbol
CG11940
Feature Type
protein_coding_gene
FlyBase ID
FBgn0261811
Gene Model Status
Current
Stock Availability
19 publicly available
Gene Summary
pico (pico) encodes an intracellular adapter protein belonging to the MRL family of proteins, which transduce signals from growth factor receptors to changes in the actin cytoskeleton. Its roles include the regulation of growth and cell migration. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)
All Summaries
Also Known As

jog, john glenn

Key Links
Genomic Location
Cytogenetic map
18F2-18F4
Sequence location
Recombination map
1-64
RefSeq locus
NC_004354 REGION:19830215..19852059
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (12 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
enables protein domain specific binding
inferred from physical interaction with UniProtKB:M9MRI4
(Morikawa et al., 2011)
enables protein phosphatase 1 binding
inferred from physical interaction with FLYBASE:flw; FB:FBgn0000711
(Bennett et al., 2006)
inferred from physical interaction with FLYBASE:Pp1-13C; FB:FBgn0003132
(Bennett et al., 2006)
inferred from physical interaction with FLYBASE:Pp1α-96A; FB:FBgn0003134
(Bennett et al., 2006)
inferred from physical interaction with FLYBASE:Pp1-87B; FB:FBgn0004103
(Bennett et al., 2006)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
enables protein-macromolecule adaptor activity
inferred from biological aspect of ancestor with PANTHER:PTN001343226
(GO Reference Genome Project, 2011-)
Biological Process (8 terms)
Terms Based on Experimental Evidence (6 terms)
CV Term
Evidence
References
involved_in actin filament organization
inferred from mutant phenotype
(Lyulcheva et al., 2008)
involved_in imaginal disc development
inferred from mutant phenotype
(Lyulcheva et al., 2008)
involved_in positive regulation of cell division
inferred from mutant phenotype
(Lyulcheva et al., 2008)
involved_in positive regulation of developmental growth
inferred from mutant phenotype
(Lyulcheva et al., 2008)
involved_in positive regulation of filopodium assembly
inferred from direct assay
(Bischoff et al., 2013)
involved_in regulation of cell size
inferred from mutant phenotype
(Lyulcheva et al., 2008)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
involved_in intracellular signal transduction
inferred from biological aspect of ancestor with PANTHER:PTN001343226
(GO Reference Genome Project, 2011-)
involved_in signal transduction
inferred from electronic annotation with InterPro:IPR000159
(InterPro Project Members, 2004-)
Cellular Component (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
colocalizes_with filopodium tip
inferred from direct assay
(Huelsmann et al., 2013)
Terms Based on Predictions or Assertions (0 terms)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
pico (pico) encodes an intracellular adapter protein belonging to the MRL family of proteins, which transduce signals from growth factor receptors to changes in the actin cytoskeleton. Its roles include the regulation of growth and cell migration. [Date last reviewed: 2019-03-14]
Summary (Interactive Fly)

signal transduction - molecular adaptor that links EGFR activation to mitogenic SRF signaling via changes in actin dynamics - required for cell growth and proliferation

Gene Model and Products
Number of Transcripts
4
Number of Unique Polypeptides
3

Please see the JBrowse view of Dmel\pico for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9VWB7)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.45

Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
pico-RA
FBtr0074804
NM_134519
6183
1162
pico-RB
FBtr0074805
NM_167686
6790
1034
pico-RC
FBtr0303995
NM_001201745
5095
1113
pico-RD
FBtr0303996
NM_001201746
5135
1034
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
pico-PA
FBpp0074573
124.4
1162
8.55
Q9VWB7
NP_608363
AAF49029
pico-PB
FBpp0074574
111.1
1034
8.47
Q8IQW0
NP_728307
AAN09520
pico-PC
FBpp0292964
118.7
1113
8.73
M9MSQ5
NP_001188674
ADV37756
pico-PD
FBpp0292965
111.1
1034
8.47
Q8IQW0
NP_001188675
ADV37757
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1034 aa isoforms: pico-PB, pico-PD
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\pico using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.18

Transcript Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
colocalizes_with filopodium tip
inferred from direct assay
(Huelsmann et al., 2013)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\pico in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 29 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 11 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of pico
Transgenic constructs containing regulatory region of pico
Aberrations (Deficiencies and Duplications) ( 0 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal - all die before end of larval stage
partially lethal - majority die, with Scer\GAL4Tub.PU
viable
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
Other Phenotypes
Allele
abnormal body size
abnormal body size, with Scer\GAL4arm.PS
abnormal body size, with Scer\GAL4Bx-MS1096
abnormal body size, with Scer\GAL4Tub.PU
abnormal size, with Scer\GAL4Bx-MS1096
abnormal size | larval stage, with Scer\GAL4hh-Gal4
abnormal sleep
decreased body size, with Scer\GAL4Act5C.PU
decreased cell number, with Scer\GAL4Bx-MS1096
decreased cell number, with Scer\GAL4ptc-559.1
decreased cell number | somatic clone, with Scer\GAL4Act5C.PU
decreased cell size, with Scer\GAL4Bx-MS1096
increased body size, with Scer\GAL4arm.PS
increased cell number, with Scer\GAL4Bx-MS1096
increased cell number, with Scer\GAL4en-e16E
increased cell number, with Scer\GAL4ptc-559.1
short lived | heat sensitive, with Scer\GAL4tin.CΔ4
some die during larval stage
visible, with Scer\GAL4pnr-MD237
Phenotype manifest in
Allele
chaeta | increased number, with Scer\GAL4pnr-MD237
cytoneme | larval stage, with Scer\GAL4hh-Gal4
imaginal disc
imaginal disc | somatic clone
mesonotum, with Scer\GAL4pnr-MD237
wing, with Scer\GAL4Bx-MS1096
wing, with Scer\GAL4en-e16E
wing blade dorsal compartment, with Scer\GAL4Bx-MS1096
wing disc posterior compartment, with Scer\GAL4hh-Gal4
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (19)
Hsap\RAPH1
9 of 14
Yes
Yes
Hsap\APBB1IP
7 of 14
No
Yes
2  
Hsap\GRB7
3 of 14
No
Yes
Hsap\GRB14
3 of 14
No
Yes
Hsap\GRB10
2 of 14
No
Yes
Hsap\COBLL1
1 of 14
No
Yes
Hsap\FYN
1 of 14
No
No
3  
Hsap\GAB1
1 of 14
No
No
0  
Hsap\GAB4
1 of 14
No
No
Hsap\MATK
1 of 14
No
No
1  
Hsap\RIN2
1 of 14
No
No
Hsap\SH2D2A
1 of 14
No
Yes
Hsap\SHD
1 of 14
No
No
Hsap\SRMS
1 of 14
No
No
Hsap\SYK
1 of 14
No
No
Hsap\TEC
1 of 14
No
No
Hsap\VAV1
1 of 14
No
No
1  
Hsap\YES1
1 of 14
No
No
Hsap\ZAP70
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (16)
Rnor\Raph1
9 of 14
Yes
Yes
Rnor\Apbb1ip
8 of 14
No
Yes
Rnor\Grb7
3 of 14
No
Yes
Rnor\Grb10
3 of 14
No
Yes
Rnor\Grb14
2 of 14
No
Yes
Rnor\Fyn
1 of 14
No
No
Rnor\Gab1
1 of 14
No
No
Rnor\Matk
1 of 14
No
No
Rnor\Rin2
1 of 14
No
No
Rnor\Shc1
1 of 14
No
No
Rnor\Sla2
1 of 14
No
Yes
Rnor\Srms
1 of 14
No
No
Rnor\Syk
1 of 14
No
No
Rnor\Vav1
1 of 14
No
No
Rnor\Yes1
1 of 14
No
No
Rnor\Zap70
1 of 14
No
No
Mus musculus (laboratory mouse) (20)
Mmus\Raph1
9 of 14
Yes
Yes
Mmus\Apbb1ip
7 of 14
No
Yes
Mmus\Grb7
3 of 14
No
Yes
Mmus\Grb10
3 of 14
No
Yes
Mmus\Grb14
3 of 14
No
Yes
Mmus\Cobll1
1 of 14
No
Yes
Mmus\Fyn
1 of 14
No
No
Mmus\Gab1
1 of 14
No
No
Mmus\Gab2
1 of 14
No
No
Mmus\Matk
1 of 14
No
No
Mmus\Rin2
1 of 14
No
No
Mmus\Shc1
1 of 14
No
No
Mmus\Shd
1 of 14
No
No
Mmus\She
1 of 14
No
No
Mmus\Sla2
1 of 14
No
Yes
Mmus\Src
1 of 14
No
No
Mmus\Syk
1 of 14
No
No
Mmus\Vav1
1 of 14
No
No
Mmus\Yes1
1 of 14
No
No
Mmus\Zap70
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (7)
Xtro\apbb1ip
5 of 13
Yes
Yes
Xtro\raph1
4 of 13
No
Yes
Xtro\abl2
1 of 13
No
No
Xtro\dgcr8
1 of 13
No
No
Xtro\frk
1 of 13
No
No
Xtro\grb7
1 of 13
No
Yes
Xtro\zap70
1 of 13
No
No
Danio rerio (Zebrafish) (17)
Drer\raph1b
11 of 14
Yes
Yes
Drer\raph1a
9 of 14
No
Yes
Drer\apbb1ip
8 of 14
No
Yes
Drer\grb7
3 of 14
No
Yes
Drer\grb10a
2 of 14
No
Yes
Drer\grb10b
2 of 14
No
Yes
Drer\blk
1 of 14
No
No
Drer\cobll1a
1 of 14
No
Yes
Drer\frk
1 of 14
No
No
Drer\fyna
1 of 14
No
No
Drer\fynb
1 of 14
No
No
Drer\gab1
1 of 14
No
No
Drer\grb14
1 of 14
No
Yes
Drer\lck
1 of 14
No
No
Drer\nck2a
1 of 14
No
No
Drer\syk
1 of 14
No
No
Drer\yrk
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (3)
Cele\mig-10
9 of 14
Yes
Yes
Cele\shc-1
1 of 14
No
No
Cele\Y37D8A.4
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (5)
Agam\AgaP_AGAP002695
12 of 12
Yes
Yes
Agam\AgaP_AGAP003638
1 of 12
No
No
Agam\AgaP_AGAP005826
1 of 12
No
No
Agam\AgaP_AGAP006270
1 of 12
No
No
Agam\AgaP_AGAP011152
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (0)
Saccharomyces cerevisiae (Brewer's yeast) (0)
Schizosaccharomyces pombe (Fission yeast) (0)
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:pico. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (3)
CG2841
1 of 13
dos
1 of 13
Src42A
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Allele
Disease
Evidence
References
Potential Models Based on Orthology ( 0 )
Human Ortholog
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
RAPH1; Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
9 of 14
609035
      APBB1IP; amyloid beta precursor protein binding family B member 1 interacting protein
      7 of 14
      609036
           
          GRB7; growth factor receptor bound protein 7
          3 of 14
          601522
              GRB14; growth factor receptor bound protein 14
              3 of 14
              601524
                  Functional Complementation Data
                  Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                  Interactions
                  Summary of Physical Interactions
                  Summary of Genetic Interactions
                  Interaction Browsers
                  View in FlyBase Interactions Browser   View in MIST tool (external link)
                  Please look at the allele data for full details of the genetic interactions
                  Starting gene(s)
                  Interaction type
                  Interacting gene(s)
                  Reference
                  pico
                  suppressible
                  bs
                  (Lyulcheva et al., 2008)
                  pico
                  suppressible
                  Egfr
                  (Lyulcheva et al., 2008)
                  pico
                  suppressible
                  ena
                  (Lyulcheva et al., 2008)
                  Starting gene(s)
                  Interaction type
                  Interacting gene(s)
                  Reference
                  Egfr
                  suppressible
                  pico
                  (Lyulcheva et al., 2008)
                  ena
                  suppressible
                  pico
                  (Lyulcheva et al., 2008)
                  Ras85D
                  suppressible
                  pico
                  (Lyulcheva et al., 2008)
                  External Data
                  Linkouts
                  DroID - A comprehensive database of gene and protein interactions.
                  MIST (protein-protein) - An integrated Molecular Interaction Database
                  Pathways
                  Signaling Pathways (FlyBase)
                  Metabolic Pathways
                  FlyBase
                  External Links
                  External Data
                  Linkouts
                  Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                  Class of Gene
                  Genomic Location and Detailed Mapping Data
                  Chromosome (arm)
                  X
                  Recombination map
                  1-64
                  Cytogenetic map
                  18F2-18F4
                  Sequence location
                  FlyBase Computed Cytological Location
                  Cytogenetic map
                  Evidence for location
                  18F2-18F4
                  Limits computationally determined from genome sequence between P{EP}EP1116&P{EP}EP1344EP1344 and P{EP}amnEP1649&P{EP}amnEP1442
                  Experimentally Determined Cytological Location
                  Cytogenetic map
                  Notes
                  References
                  Experimentally Determined Recombination Data
                  Location

                  1-64

                  (FlyBase, 2016)

                  1-63.1

                  (Comeron et al., 2012)
                  Left of (cM)
                  Right of (cM)
                  Notes
                  Stocks and Reagents
                  Stocks (19)
                  Genomic Clones (21)
                  cDNA Clones (78)
                   

                  Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

                  cDNA clones, fully sequenced
                  BDGP DGC clones
                  Other clones
                  Drosophila Genomics Resource Center cDNA clones

                  For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                  cDNA Clones, End Sequenced (ESTs)
                  BDGP DGC clones
                  Other clones
                  RNAi and Array Information
                  Linkouts
                  DRSC - Results frm RNAi screens
                  Antibody Information
                  Laboratory Generated Antibodies
                   
                  Commercially Available Antibodies
                   
                  Cell Line Information
                  Publicly Available Cell Lines
                   
                    Other Stable Cell Lines
                     
                      Other Comments

                      Mutant larvae are dramatically reduced in size, with severely reduced endoreduplicated tissue and little or no imaginal disc tissue. They eventually die following an extended larval period of up to three weeks. Overexpression of pico results in the wing imaginal disc results in an increase in overall tissue size.

                      (Lioultcheva and Bennett, 2005)

                      dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.

                      (Kiger et al., 2003)
                      Relationship to Other Genes
                      Source for database merge of

                      Source for merge of: pico jog

                      (Lyulcheva et al., 2008)

                      Source for merge of: CG11940 BcDNA:LP01106

                      (FlyBase, 1996-)
                      Additional comments

                      Source for merge of CG11940 BcDNA:LP01106 was a shared cDNA ( date:030728 ).

                      (FlyBase, 1996-)
                      Nomenclature History
                      Source for database identify of

                      Source for identity of: jog CG11940

                      (Konduri and Beckingham, 2007)
                      Nomenclature comments
                      Etymology

                      Named "jog" after John Glenn, American astronaut.

                      (Konduri and Beckingham, 2007)
                      Synonyms and Secondary IDs (9)
                      Datasets (0)
                      Study focus (0)
                      Experimental Role
                      Project
                      Project Type
                      Title
                      Study result (0)
                      Result
                      Result Type
                      Title
                      External Crossreferences and Linkouts ( 59 )
                      Sequence Crossreferences
                      NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                      GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                      RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                      UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
                      UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
                      Other crossreferences
                      AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
                      DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
                      EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
                      FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
                      InterPro - A database of protein families, domains and functional sites
                      KEGG Genes - Molecular building blocks of life in the genomic space.
                      MARRVEL_MODEL - MARRVEL (model organism gene)
                      Linkouts
                      Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                      DroID - A comprehensive database of gene and protein interactions.
                      DRSC - Results frm RNAi screens
                      Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                      FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                      FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                      Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                      FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.
                      iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
                      Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
                      MIST (protein-protein) - An integrated Molecular Interaction Database
                      Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                      References (75)