lack, dSmurf, lethal with a checkpoint kinase, dSmurf1, Smurf1
ubiquitin-protein ligase that regulates Decapentaplegic pathway signaling by targeting Mothers against Dpp for degradation - the F-box protein Slimb controls dSmurf protein turnover to regulate the Hippo pathway
Interacts with phosphorylated MAD.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Smurf using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Smurf in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Smurf lack
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.