FlyBase Allele Report: Scer\GAL4[P0206]

Drives expression in the prothoracic gland and corpus allatum from embryonic stage 17 through third instar larval stage; also drives expression in the larval optic lobes.

(FlyBase Curators, 2017)

ScerGAL4^P0206 drives strong expression in the larval ring gland and optic lobes. Additional staining is seen in other parts of the larval central brain.

(Vallejo et al., 2015)

In the ring gland, ScerGAL4^P0206 is expressed moderately throughout the prothoracic gland and strongly in the corpus allatum.

(Mirth et al., 2005)

Marker for

ring gland

(Suster and Bate, 2002)

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell growth, with Pi3K92E^UAS.Tag:MYC

(Colombani et al., 2005, Colombani et al., 2005)

abnormal developmental rate, with NLaz^UAS.cBa

(Romão et al., 2021)

abnormal developmental rate, with Noc1^RNAi.UAS.cUa

(Destefanis et al., 2022)

abnormal developmental rate, with Noc2^HMJ03129

(Destefanis et al., 2022)

abnormal developmental rate, with Noc3^HMJ23361

(Destefanis et al., 2022)

abnormal developmental rate, with Npc1a^KK101077

(Danielsen et al., 2016)

abnormal developmental rate, with Pi3K92E^{D954A.UAS.Tag:MYC}

(Colombani et al., 2005)

abnormal developmental rate, with Pi3K92E^UAS.Tag:MYC

(Colombani et al., 2005)

abnormal developmental rate, with upd1^UAS.cUa

(Romão et al., 2021)

abnormal developmental rate, with upd3^UAS.GFP

(Romão et al., 2021)

abnormal developmental rate | larval stage, with Hr4^RNAi.UAS.cOa

(Ou et al., 2011)

abnormal developmental rate | larval stage, with Noc1^JF02014

(Mirzoyan et al., 2023)

abnormal developmental rate | second instar larval stage, with Hr4^UAS.cQa

(Ou et al., 2011)

abnormal developmental rate | second instar larval stage, with Pten^UAS.cGb

(Mirth et al., 2005)

abnormal developmental rate | third instar larval stage, with Pten^UAS.cGb

(Mirth et al., 2005)

atrophy | larval stage, with Noc1^RNAi.UAS.cUa

(Destefanis et al., 2022)

decreased body size, with Pi3K92E^UAS.Tag:MYC

(Colombani et al., 2005)

decreased body size | pharate adult stage, with Pi3K92E^UAS.Tag:MYC

(Mirth et al., 2005)

decreased body size | prepupal stage, with Hr4^RNAi.UAS.cOa

(Ou et al., 2011)

decreased cell number, with Pi3K92E^UAS.Tag:MYC

(Colombani et al., 2005)

decreased cell size, with Pi3K92E^UAS.Tag:MYC

(Colombani et al., 2005)

increased body size, with Pi3K92E^{D954A.UAS.Tag:MYC}

(Colombani et al., 2005)

increased body size | first instar larval stage, with Hr4^UAS.cQa

(Ou et al., 2011)

increased body size | larval stage, with Noc1^RNAi.UAS.cUa

(Destefanis et al., 2022)

increased body size | larval stage, with Noc2^HMJ03129

(Destefanis et al., 2022)

increased body size | larval stage, with Noc3^HMJ23361

(Destefanis et al., 2022)

increased body size | larval stage | progressive, with Noc1^JF02014

(Mirzoyan et al., 2023)

increased body size | pharate adult stage, with Pten^UAS.cGb

(Mirth et al., 2005)

increased body size | pupal stage, with Npc1a^KK101077

(Danielsen et al., 2016)

increased body size | second instar larval stage, with Pten^UAS.cGb

(Mirth et al., 2005)

increased body size | third instar larval stage, with TNPV\ank1^UASp.cDa

(Valzania et al., 2014)

increased body weight | larval stage | progressive, with Noc1^JF02014

(Mirzoyan et al., 2023)

increased cell death | larval stage, with Noc1^JF02014

(Mirzoyan et al., 2023)

increased cell number, with Pi3K92E^{D954A.UAS.Tag:MYC}

(Colombani et al., 2005)

increased cell size | larval stage, with Noc1^JF02014

(Mirzoyan et al., 2023)

increased cell size | larval stage, with Noc1^RNAi.UAS.cUa

(Destefanis et al., 2022)

increased rate of feeding behavior | larval stage, with Noc1^JF02014

(Mirzoyan et al., 2023)

lethal, with br^Z3.UAS

(Zhou et al., 2004)

lethal - all die before end of larval stage, with br^Z4.UAS

(Zhou et al., 2004)

lethal - all die before end of larval stage, with Noc1^JF02014

(Mirzoyan et al., 2023)

lethal - all die before end of larval stage, with Noc1^RNAi.UAS.cUa

(Destefanis et al., 2022)

lethal - all die before end of larval stage, with Noc2^HMJ03129

(Destefanis et al., 2022)

lethal - all die before end of larval stage, with Noc3^HMJ23361

(Destefanis et al., 2022)

lethal - all die before end of larval stage, with TNPV\ank1^UASp.cDa

(Valzania et al., 2014)

lethal - all die before end of pupal stage | partially, with Pten^UAS.cGb

(Mirth et al., 2005)

some die during pupal stage | partially, with Pten^UAS.cGb

(Mirth et al., 2005)

some die during third instar larval stage, with br^Z4.UAS

(Zhou et al., 2004)

viable, with Noc1^{UAS.ORF.GW.Tag:HA}

(Destefanis et al., 2022)

Phenotype Manifest In

embryonic/larval corpus allatum, with Pten^UAS.cGb

(Mirth et al., 2005)

embryonic/larval fat body, with Hr4^UAS.cQa

(Ou et al., 2011)

embryonic/larval fat body | larval stage, with Noc1^JF02014

(Mirzoyan et al., 2023)

embryonic/larval fat body | larval stage, with Noc1^RNAi.UAS.cUa

(Destefanis et al., 2022)

embryonic/larval heart | larval stage, with Noc1^JF02014

(Mirzoyan et al., 2023)

embryonic/larval hemolymph | larval stage, with Noc1^JF02014

(Mirzoyan et al., 2023)

eye, with Pi3K92E^{D954A.UAS.Tag:MYC}

(Colombani et al., 2005)

eye, with Pi3K92E^UAS.Tag:MYC

(Colombani et al., 2005)

larval cardial cell | larval stage, with Noc1^JF02014

(Mirzoyan et al., 2023)

larval fat cell of larval fat body, with Noc1^JF02014

(Mirzoyan et al., 2023)

larval insulin secreting cell of pars intercerebralis, with Noc1^JF02014

(Mirzoyan et al., 2023)

lipid droplet | increased number | larval stage, with Noc1^JF02014

(Mirzoyan et al., 2023)

prothoracic gland, with br^Z1.UAS

(Zhou et al., 2004)

prothoracic gland, with br^Z2.UAS

(Zhou et al., 2004)

prothoracic gland, with br^Z3.UAS

(Zhou et al., 2004)

prothoracic gland, with Pi3K92E^UAS.Tag:MYC

(Colombani et al., 2005)

prothoracic gland, with Pten^UAS.cGb

(Mirth et al., 2005)

prothoracic gland | larval stage, with Noc1^RNAi.UAS.cUa

(Destefanis et al., 2022)

prothoracic gland | third instar larval stage, with Npc1a^KK101077

(Danielsen et al., 2016)

puparium cuticle, with Pten^UAS.cGb

(Mirth et al., 2005)

ring canal, with Pi3K92E^UAS.Tag:MYC

(Colombani et al., 2005, Colombani et al., 2005)

ring gland, with Hr4^UAS.cQa

(Ou et al., 2011)

wing, with Pi3K92E^{D954A.UAS.Tag:MYC}

(Colombani et al., 2005)

wing, with Pi3K92E^UAS.Tag:MYC

(Colombani et al., 2005)

wing, with Pten^UAS.cGb

(Mirth et al., 2005)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^P0206, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, suppressible | partially by dome^GD14494, Scer\GAL4^P0206, Scer\GAL4^ap-md544

(Romão et al., 2021)

BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^P0206, Scer\GAL4^ap-md544 has abnormal developmental rate phenotype, suppressible by mir-ban^{sponge.UAS.DsRed(Unk)}, Scer\GAL4^P0206, Scer\GAL4^ap-md544

(Romão et al., 2021)

Npc1a^KK101077, Scer\GAL4^P0206 has abnormal developmental rate phenotype, suppressible by Atg1^UAS.cSa/Atg13^UAS.cCa, Scer\GAL4^P0206

(Danielsen et al., 2016)

Npc1a^KK101077, Scer\GAL4^P0206 has increased body size | pupal stage phenotype, suppressible by Atg1^UAS.cSa/Atg13^UAS.cCa, Scer\GAL4^P0206

(Danielsen et al., 2016)

Hr4^UAS.cQa, Scer\GAL4^P0206 has abnormal developmental rate | second instar larval stage phenotype, suppressible by Ras85D^V12.UAS, Scer\GAL4^P0206

(Ou et al., 2011)

Pi3K92E^UAS.Tag:MYC, Scer\GAL4^P0206 has decreased cell number phenotype, suppressible by foxo²¹

(Colombani et al., 2005)

Pi3K92E^UAS.Tag:MYC, Scer\GAL4^P0206 has decreased cell size phenotype, suppressible by foxo²¹

(Colombani et al., 2005)

Pi3K92E^UAS.Tag:MYC, Scer\GAL4^P0206 has decreased body size phenotype, suppressible by foxo²¹

(Colombani et al., 2005)

Pi3K92E^UAS.Tag:MYC, Scer\GAL4^P0206 has abnormal cell growth phenotype, suppressible by foxo²¹

(Colombani et al., 2005)

Suppressor of

Statement

Reference

dome^GD14494, Scer\GAL4^P0206, Scer\GAL4^ap-md544 is a suppressor | partially of abnormal developmental rate phenotype of BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^P0206, Scer\GAL4^ap-md544

(Romão et al., 2021)

mir-ban^{sponge.UAS.DsRed(Unk)}, Scer\GAL4^P0206, Scer\GAL4^ap-md544 is a suppressor of abnormal developmental rate phenotype of BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^P0206, Scer\GAL4^ap-md544

(Romão et al., 2021)

Scer\GAL4^P0206, Atg1^UAS.cSa/Atg13^UAS.cCa is a suppressor of abnormal developmental rate phenotype of Npc1a^KK101077, Scer\GAL4^P0206

(Danielsen et al., 2016)

Scer\GAL4^P0206, Atg1^UAS.cSa/Atg13^UAS.cCa is a suppressor of increased body size | pupal stage phenotype of Npc1a^KK101077, Scer\GAL4^P0206

(Danielsen et al., 2016)

Ras85D^V12.UAS, Scer\GAL4^P0206 is a suppressor of abnormal developmental rate | second instar larval stage phenotype of Hr4^UAS.cQa, Scer\GAL4^P0206

(Ou et al., 2011)

Scer\GAL4^P0206/Hr4^UAS.cQa is a suppressor of abnormal developmental rate | larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^phtm.PO

(Ou et al., 2011)

Scer\GAL4^P0206/Hr4^UAS.cQa is a suppressor of decreased body size | pupal stage phenotype of Ras85D^V12.UAS, Scer\GAL4^phtm.PO

(Ou et al., 2011)

NOT Suppressor of

Statement

Reference

nvd^UAS.cYa/Scer\GAL4^P0206 is a non-suppressor of abnormal developmental rate | larval stage phenotype of Ptth^120F2A/Ptth^Delta

(Shimell et al., 2018)

Scer\GAL4^P0206/spok^UAS.cOa is a non-suppressor of abnormal developmental rate | larval stage phenotype of Ptth^120F2A/Ptth^Delta

(Shimell et al., 2018)

Scer\GAL4^P0206/dib^UAS.cOa is a non-suppressor of abnormal developmental rate | larval stage phenotype of Ptth^120F2A

(Shimell et al., 2018)

Phenotype Manifest In

Suppressed by

Statement

Reference

Noc1^JF02014, Scer\GAL4^P0206 has embryonic/larval fat body | larval stage phenotype, suppressible by grnd^unspecified/grnd[+]

(Mirzoyan et al., 2023)

Noc1^JF02014, Scer\GAL4^P0206 has embryonic/larval fat body | larval stage phenotype, suppressible by egr¹/egr[+]

(Mirzoyan et al., 2023)

Noc1^JF02014, Scer\GAL4^P0206 has embryonic/larval fat body | larval stage phenotype, suppressible by egr³/egr[+]

(Mirzoyan et al., 2023)

Noc1^JF02014, Scer\GAL4^P0206 has embryonic/larval fat body | larval stage phenotype, suppressible by spz⁴

(Mirzoyan et al., 2023)

Noc1^JF02014, Scer\GAL4^P0206 has embryonic/larval fat body | larval stage phenotype, suppressible by Rel^E20

(Mirzoyan et al., 2023)

Npc1a^KK101077, Scer\GAL4^P0206 has prothoracic gland | third instar larval stage phenotype, suppressible by gig^UAS.cTa/Tsc1^UAS.cTa, Scer\GAL4^P0206

(Danielsen et al., 2016)

Hr4^UAS.cQa, Scer\GAL4^P0206 has ring gland phenotype, suppressible by Ras85D^V12.UAS, Scer\GAL4^P0206

(Ou et al., 2011)

Suppressor of

Statement

Reference

gig^UAS.cTa/Tsc1^UAS.cTa, Scer\GAL4^P0206 is a suppressor of prothoracic gland | third instar larval stage phenotype of Npc1a^KK101077, Scer\GAL4^P0206

(Danielsen et al., 2016)

Scer\GAL4^P0206/Hr4^UAS.cQa is a suppressor of prothoracic gland phenotype of Ras85D^V12.UAS, Scer\GAL4^phtm.PO

(Ou et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^P0206 is a suppressor of ring gland phenotype of Hr4^UAS.cQa, Scer\GAL4^P0206

(Ou et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^P0206/RpS6^UAS.cLa rescues RpS6^WG1288

(Lin et al., 2011)

Scer\GAL4^P0206/dib^UAS.cOa rescues dib^P3/dib^F8

(Wang et al., 2011)

Scer\GAL4^P0206/Npc1a^UAS.cFa rescues Npc1a^57A

(Fluegel et al., 2006)

Fails to rescue

Scer\GAL4^P0206/Nf1^UAS.cWa fails to rescue Nf1^unspecified

(Walker et al., 2006)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

606369

w^*; Ptth^120F2A P{GAL4}P0206

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^P0206

Name Synonyms

Secondary FlyBase IDs

References (43)

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