Ub, ubiquitin, polyubiquitin, Ubi-p, ubi63E
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Apparent introns not annotated: probable artifacts due to repetitive sequence.
Gene model reviewed during 5.46
4.4 (northern blot)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ubi-p63E using the Feature Mapper tool.
Ubi-p63E transcript is expressed in spermatocytes. Expression is isoform-specific; very little Ubi-p63E-RC transcript is detected in spermatocytes, while Ubi-p63E-RA has higher expression levels than other isoforms.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Ubi-p63E in GBrowse 2
Same map position as 63F early ecdysone-induced puff.
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
Area matching Drosophila Ubiquitin gene, Acc. No. M22428.
Antibody staining of polytene chromosomes shows that ubiquitin is mainly associated with the compact and stabilized structure that forms the bands rather than with the more decondensed and destabilized protein-DNA structure that forms interbands and puffs.
Structural gene for ubiquitin (Arribas, Sampedro and Izquierdo, 1988); structure and expression described by Lee, Simon and Lis (1988). Threefold increase in level of gene by heat shock. A Ubi-p63E-lacZ fusion gene introduced by germ line transformation has been expressed at high levels at all life stages tested (embryonic, larval, pupal and adult).
Named 'magellan' because mutant spermatocytes arrest development with abnormal structures that resemble Magellanic clouds.