dAda2b
Please see the JBrowse view of Dmel\Ada2b for information on other features
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Multiphase exon postulated: exon reading frame differs in alternative transcripts; overlap >20aa (see FBrf0221014).
Gene model reviewed during 5.47
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
Multiphasic exons (use of alternative reading frames in different transcripts) supported (FBrf0221014).
Interacts with Gcn5 and Ada3 as part of a GCN5-containing ADA multiprotein complex (PubMed:12482983). Associated with a SAGA-type complex that also contains Taf5, e(y)1/Taf9, Taf10, Spt3 and Taf1 (PubMed:12697829).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ada2b using the Feature Mapper tool.
Comment: maternally deposited
GBrowse - Visual display of RNA-Seq signals
View Dmel\Ada2b in GBrowse 23-48
3-48
3-44.8
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
dsRNA has been made from templates generated with primers directed against this gene.
Ada2b is part of a SAGA-type complex.
Loss of Ada2b function results in segmentation defects as well as massive apoptosis at the onset of early embryonic differentiation.
Mutants show pupal lethality.