FlyBase Gene Report: Dmel\Lgr3

second instar larval stage | female

(Meissner et al., 2016)

second instar larval stage

(Meissner et al., 2016)

early third instar larval stage | male

(Meissner et al., 2016)

early third instar larval stage | female

(Meissner et al., 2016)

early third instar larval stage

(Meissner et al., 2016)

late third instar larval stage | male

(Meissner et al., 2016)

late third instar larval stage | female

(Meissner et al., 2016)

(Meissner et al., 2016)

(Meissner et al., 2016)

pupal stage P6 | male

Comment: ~21hrs APF

(Meissner et al., 2016)

pupal stage P6 | female

Comment: ~21hrs APF

(Meissner et al., 2016)

pupal stage P6

Comment: ~21hrs APF

(Meissner et al., 2016)

pupal stage P7 | male

Comment: ~43hrs APF

(Meissner et al., 2016)

pupal stage P7 | female

Comment: ~43hrs APF

(Meissner et al., 2016)

pupal stage P7

Comment: ~43hrs APF

(Meissner et al., 2016)

pharate adult stage P9 | male

pharate adult stage P9 | female

Comment: ~71hrs APF

(Meissner et al., 2016)

Comment: ~71hrs APF

(Meissner et al., 2016)

pharate adult stage P9

pharate adult stage P14 | male

Comment: ~71hrs APF

(Meissner et al., 2016)

pharate adult stage P14 | female

Comment: ~90hrs APF

(Meissner et al., 2016)

Comment: ~90hrs APF

(Meissner et al., 2016)

pharate adult stage P14

Comment: ~90hrs APF

(Meissner et al., 2016)

(Meissner et al., 2016)

(Meissner et al., 2016)

(Meissner et al., 2016)

wandering third instar larval stage | male

(Meissner et al., 2016)

RT-PCR

Stage

Tissue/Position (including subcellular localization)

Reference

larval central nervous system

(Van Hiel et al., 2015)

embryonic/larval salivary gland

(Van Hiel et al., 2015)

embryonic/larval tracheal section

(Van Hiel et al., 2015)

embryonic/larval Malpighian tubule

(Van Hiel et al., 2015)

embryonic/larval midgut

(Van Hiel et al., 2015)

embryonic/larval hindgut

(Van Hiel et al., 2015)

embryonic/larval fat body

(Van Hiel et al., 2015)

gonad

(Van Hiel et al., 2015)

wandering third instar larval stage | female

larval central nervous system

(Van Hiel et al., 2015)

embryonic/larval salivary gland

(Van Hiel et al., 2015)

embryonic/larval tracheal section

(Van Hiel et al., 2015)

embryonic/larval Malpighian tubule

(Van Hiel et al., 2015)

embryonic/larval midgut

(Van Hiel et al., 2015)

embryonic/larval hindgut

(Van Hiel et al., 2015)

embryonic/larval fat body

(Van Hiel et al., 2015)

gonad

(Van Hiel et al., 2015)

ovary

Comment: low level

(Van Hiel et al., 2015)

crop

(Van Hiel et al., 2015)

rectum

(Van Hiel et al., 2015)

adult brain

(Van Hiel et al., 2015)

uterus

(Van Hiel et al., 2015)

spermatheca

Comment: low level

(Van Hiel et al., 2015)

adult muscle system

Comment: low level

(Van Hiel et al., 2015)

adult salivary gland

(Van Hiel et al., 2015)

adult ventral nerve cord

Comment: low level

(Van Hiel et al., 2015)

adult Malpighian tubule

Comment: low level

(Van Hiel et al., 2015)

adult midgut

Comment: low level

(Van Hiel et al., 2015)

adult hindgut

(Van Hiel et al., 2015)

adult fat body

(Van Hiel et al., 2015)

third instar larval stage

testis

(Van Hiel et al., 2015)

crop

(Van Hiel et al., 2015)

rectum

(Van Hiel et al., 2015)

adult brain

(Van Hiel et al., 2015)

adult muscle system

(Van Hiel et al., 2015)

adult salivary gland

(Van Hiel et al., 2015)

adult ventral nerve cord

Comment: low level

(Van Hiel et al., 2015)

male accessory gland

Comment: low level

(Van Hiel et al., 2015)

seminal vesicle

(Van Hiel et al., 2015)

ejaculatory bulb

(Van Hiel et al., 2015)

adult Malpighian tubule

Comment: low level

(Van Hiel et al., 2015)

adult midgut

Comment: low level

(Van Hiel et al., 2015)

adult hindgut

(Van Hiel et al., 2015)

adult fat body

(Van Hiel et al., 2015)

Additional Descriptive Data

Lgr3 expression overlaps completely with that of ScerGAL4^VP16.Lgr3, with the exception of the adult abdominal neuromere where it is expressed in a few more cells.

(Meissner et al., 2016)

Lgr3 transcripts are expressed throughout development with a peak in first instar larvae. Transcripts are more abundant in males than females and the difference increases with age. Transcripts are observed in a broad range of tissues in wandering third instar larvae and in adults. The highest levels are observed in CNS and many tissues including larval midgut, hindgut, and gonads, and adult Malpighian tubule have higher levels in males than females. Levels are elevated in fat body in female relative to male.

(Van Hiel et al., 2015)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

Reporter: P{GMR17G11-GAL4}

Stage

Tissue/Position (including subcellular localization)

Reference

larval central nervous system | restricted

(Vallejo et al., 2015)

larval pacemaker neuron | subset

(Vallejo et al., 2015)

(Meissner et al., 2016)

larval central nervous system | restricted

(Meissner et al., 2016)

Reporter: P{GMR19B09-GAL4}

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage

(Vallejo et al., 2015)

larval insulin secreting cell of pars intercerebralis

(Vallejo et al., 2015)

third instar larval stage

larval pars intercerebralis | restricted

(Garelli et al., 2015)

larval gnathal ganglion | restricted

(Garelli et al., 2015)

(Garelli et al., 2015)

larval neuron | subset of larval central nervous system

(Colombani et al., 2015)

flange | intense | restricted

(Jenett and Svirskas, 2012.9.24)

(Meissner et al., 2016)

larval central nervous system | restricted

(Meissner et al., 2016)

Reporter: P{GMR19B09-lexA}

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage

(Vallejo et al., 2015)

larval insulin secreting cell of pars intercerebralis

(Vallejo et al., 2015)

third instar larval stage

larval pars intercerebralis | restricted

(Garelli et al., 2015)

larval insulin secreting cell of pars intercerebralis

larval neuron | subset of larval central nervous system

(Colombani et al., 2015)

(Colombani et al., 2015)

(Meissner et al., 2016)

second instar larval stage | male

adult median bundle | faint

(Meissner et al., 2016)

Reporter: P{Lgr3-GAL4::VP16} PBac{Lgr3-GAL4::VP16}

Stage

Tissue/Position (including subcellular localization)

Reference

second instar larval stage | female

(Meissner et al., 2016)

second instar larval stage

(Meissner et al., 2016)

early third instar larval stage | male

(Meissner et al., 2016)

early third instar larval stage | female

(Meissner et al., 2016)

early third instar larval stage

(Meissner et al., 2016)

(Meissner et al., 2016)

larval neuron | subset of larval central nervous system

(Colombani et al., 2015)

late third instar larval stage | male

(Meissner et al., 2016)

late third instar larval stage | female

(Meissner et al., 2016)

(Meissner et al., 2016)

pupal stage P6 | male

Comment: ~21hrs APF

(Meissner et al., 2016)

pupal stage P6 | female

Comment: ~21hrs APF

(Meissner et al., 2016)

pupal stage P6

Comment: ~21hrs APF

(Meissner et al., 2016)

pupal stage P7 | male

Comment: ~43hrs APF

(Meissner et al., 2016)

pupal stage P7 | female

Comment: ~43hrs APF

(Meissner et al., 2016)

pupal stage P7

Comment: ~43hrs APF

(Meissner et al., 2016)

pharate adult stage P9 | male

pharate adult stage P9 | female

Comment: ~71hrs APF

(Meissner et al., 2016)

Comment: ~71hrs APF

(Meissner et al., 2016)

pharate adult stage P9

pharate adult stage P14 | male

Comment: ~71hrs APF

(Meissner et al., 2016)

pharate adult stage P14 | female

Comment: ~90hrs APF

(Meissner et al., 2016)

Comment: ~90hrs APF

(Meissner et al., 2016)

pharate adult stage P14

Comment: ~90hrs APF

(Meissner et al., 2016)

(Meissner et al., 2016)

(Meissner et al., 2016)

(Meissner et al., 2016)

(Meissner et al., 2016)

Reporter: P{R19B09.1-GAL4}

Stage

Tissue/Position (including subcellular localization)

Reference

(Meissner et al., 2016)

(Meissner et al., 2016)

Reporter: P{R19B09.2-GAL4}

Stage

Tissue/Position (including subcellular localization)

Reference

(Meissner et al., 2016)

(Meissner et al., 2016)

Reporter: P{R19B09.3A-GAL4}

Stage

Tissue/Position (including subcellular localization)

Reference

(Meissner et al., 2016)

(Meissner et al., 2016)

Reporter: P{R19B09.3B-GAL4}

Stage

Tissue/Position (including subcellular localization)

Reference

(Meissner et al., 2016)

(Meissner et al., 2016)

Reporter: P{R19B09.3C-GAL4}

Stage

Tissue/Position (including subcellular localization)

Reference

(Meissner et al., 2016)

(Meissner et al., 2016)

Reporter: P{R19B09.3D-GAL4}

Stage

Tissue/Position (including subcellular localization)

Reference

(Meissner et al., 2016)

(Meissner et al., 2016)

Reporter: P{R19B09.3E-GAL4}

Stage

Tissue/Position (including subcellular localization)

Reference

(Meissner et al., 2016)

(Meissner et al., 2016)

Reporter: P{R19B09.3-GAL4}

Stage

Tissue/Position (including subcellular localization)

Reference

(Meissner et al., 2016)

(Meissner et al., 2016)

Reporter: TI{CRIMIC.TG4.2}Lgr3^{CR00347-TG4.2}

Stage

Tissue/Position (including subcellular localization)

Reference