FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\Elp3
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General Information
Symbol
Dmel\Elp3
Species
D. melanogaster
Name
Elongator complex protein 3
Annotation Symbol
CG15433
Feature Type
protein_coding_gene
FlyBase ID
FBgn0031604
Gene Model Status
Current
Stock Availability
12 publicly available
Enzyme Name (EC)
tRNA carboxymethyluridine synthase (2.3.1.311)
histone acetyltransferase (2.3.1.48)
Gene Summary
Elongator complex protein 3 (Elp3) encodes a Lysine (K) acetyltransferase (KAT) that resides primarily in the cytoplasm of neurons. It acetylates the product of brp in an opposite reaction to the product of HDAC6 to regulate T-bar morphology and function, and unlike most KATs it does not acetylate histones. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)
All Summaries
Also Known As

Elongator protein 3

Key Links
Genomic Location
Cytogenetic map
24F2-24F2
Sequence location
Recombination map
2-12
RefSeq locus
NT_033779 REGION:4444732..4446765
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (25 terms)
Molecular Function (6 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
enables acetyltransferase activity
inferred from mutant phenotype
(Planelles-Herrero et al., 2022)
enables protein-lysine-acetyltransferase activity
inferred from direct assay
(Miśkiewicz et al., 2011)
Terms Based on Predictions or Assertions (4 terms)
CV Term
Evidence
References
enables acyltransferase activity, transferring groups other than amino-acyl groups
inferred from electronic annotation with InterPro:IPR000182
(InterPro Project Members, 2004-)
enables catalytic activity
inferred from electronic annotation with InterPro:IPR006638, InterPro:IPR007197
(InterPro Project Members, 2004-)
enables iron-sulfur cluster binding
inferred from electronic annotation with InterPro:IPR006638, InterPro:IPR007197
(InterPro Project Members, 2004-)
enables tRNA uridine(34) acetyltransferase activity
inferred from sequence or structural similarity with UniProtKB:Q1ZXC6
(Gene Ontology Curators, 2002-)
Biological Process (14 terms)
Terms Based on Experimental Evidence (11 terms)
CV Term
Evidence
References
involved_in cytoskeletal matrix organization at active zone
inferred from mutant phenotype
(Miśkiewicz et al., 2011)
involved_in establishment of mitotic spindle asymmetry
inferred from direct assay
(Planelles-Herrero et al., 2022)
involved_in hemopoiesis
inferred from mutant phenotype
(Walker et al., 2011)
involved_in instar larval development
inferred from mutant phenotype
(Walker et al., 2011)
involved_in locomotory behavior
inferred from mutant phenotype
(Singh et al., 2010)
involved_in long-term memory
inferred from mutant phenotype
(Yu et al., 2018)
involved_in regulation of photoreceptor cell axon guidance
inferred from mutant phenotype
(Simpson et al., 2009)
involved_in sleep
inferred from mutant phenotype
(Singh et al., 2010)
involved_in synapse organization
inferred from mutant phenotype
(Simpson et al., 2009)
involved_in synaptic assembly at neuromuscular junction
inferred from mutant phenotype
(Singh et al., 2010)
involved_in tRNA modification
inferred from mutant phenotype
(Planelles-Herrero et al., 2022)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
involved_in regulation of transcription by RNA polymerase II
inferred from sequence or structural similarity with UniProtKB:Q9H9T3
(Gene Ontology Curators, 2002-)
involved_in tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation
inferred from biological aspect of ancestor with PANTHER:PTN000123913
(GO Reference Genome Project, 2011-)
involved_in tRNA wobble uridine modification
inferred from sequence or structural similarity with UniProtKB:Q1ZXC6
(Gene Ontology Curators, 2002-)
Cellular Component (5 terms)
Terms Based on Experimental Evidence (4 terms)
CV Term
Evidence
References
located_in cytoplasm
inferred from direct assay
(Yu et al., 2018)
located_in cytosol
inferred from direct assay
(Miśkiewicz et al., 2011)
part_of elongator holoenzyme complex
inferred from direct assay
(Planelles-Herrero et al., 2022)
located_in synapse
inferred from direct assay
(Miśkiewicz et al., 2011)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
is_active_in cytoplasm
inferred from biological aspect of ancestor with PANTHER:PTN000123913
(GO Reference Genome Project, 2011-)
located_in cytoplasm
inferred from sequence or structural similarity with UniProtKB:Q9H9T3
(Gene Ontology Curators, 2002-)
part_of elongator holoenzyme complex
inferred from biological aspect of ancestor with PANTHER:PTN000123915
(GO Reference Genome Project, 2011-)
is_active_in nucleus
inferred from biological aspect of ancestor with PANTHER:PTN000123915
(GO Reference Genome Project, 2011-)
located_in nucleus
inferred from sequence or structural similarity with UniProtKB:Q9H9T3
(Zhu et al., 2007)
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the ELP3 family. (Q9VQZ6)
Protein Signatures (InterPro)
Catalytic Activity (EC/Rhea)
protein-lysine-acetyltransferase activity
L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+) (2.3.1.48)
RHEA 45948: tRNA uridine(34) acetyltransferase activity
uridine(34) in tRNA + acetyl-CoA + S-adenosyl-L-methionine + H2O = 5-(carboxymethyl)uridine(34) in tRNA + 5'-deoxyadenosine + L-methionine + CoA + 2 H(+) (2.3.1.311)
RHEA 61020:
Summaries
Gene Snapshot
Elongator complex protein 3 (Elp3) encodes a Lysine (K) acetyltransferase (KAT) that resides primarily in the cytoplasm of neurons. It acetylates the product of brp in an opposite reaction to the product of HDAC6 to regulate T-bar morphology and function, and unlike most KATs it does not acetylate histones. [Date last reviewed: 2019-03-07]
Gene Group (FlyBase)
ELONGATOR HOLOENZYME COMPLEX -
Elongator is a conserved 0.8-MDa protein complex composed of six subunits, Elp1-6, comprising two copies of each subunit arranged in two subcomplexes: Elp123 and Elp456. The catalytic subunit Elp3 harbours a conserved lysine acetyl-transferase (KAT) and a S-adenosyl-L-methionine (SAM) domain, which mediate acetylation and methylation, respectively. The main function of Elongator is the regulation of translation through targeted transfer-RNA modification. (Adapted from FBrf0254982.)
UNCLASSIFIED PROTEIN-LYSINE ACETYLTRANSFERASES -
This group comprises lysine N-acetyltransferases that do not classify under other groups in FlyBase.
Protein Function (UniProtKB)
Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:36302967). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:36302967). Can acetylate proteins including histone H3 and brp/bruchpilot but is not a major acetyltransferase of tubulin; acetylation of brp plays a role in maintaining the organization of the presynaptic active zone (PubMed:22153374). Binding by the elongator complex stabilizes microtubules and promotes their growth (PubMed:36302967). This induces central spindle asymmetry, promoting polarized signaling endosome trafficking during asymmetric cell division and cell fate assignation of sensory organ precursor cells (PubMed:36302967). Required in both motoneurons and muscles to maintain the organization of presynaptic active zones and postsynaptic glutamate receptor clusters (PubMed:22153374). Plays a role in the control of synaptic bouton expansion (PubMed:20626565). Required for larval development (PubMed:21288872). Involved in protein synthesis-dependent long-term memory formation, probably as part of the elongator complex (PubMed:29545390).
(UniProt, Q9VQZ6)
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Elp3 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9VQZ6)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.47

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Elp3-RA
FBtr0077439
NM_134990
1863
552
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
Elp3-PA
FBpp0077129
62.8
552
8.79
Q9VQZ6
NP_608834
AAF51012
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Subunit Structure (UniProtKB)

Component of the elongator complex composed of Elp1, Elp2, Elp3, Elp4, Elp5 and Elp6 (PubMed:36302967). The elongator complex associates with and stabilizes microtubules; efficient interaction requires the full complex (PubMed:36302967).

(UniProt, Q9VQZ6)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Elp3 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

1.16

Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 4 -- 6
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 7 -- 8
anterior endoderm anlage
(Fisher et al., 2012)
head mesoderm
(Fisher et al., 2012)
hindgut anlage
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
posterior endoderm
(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
embryonic stage 9 -- 10
anterior endoderm
(Fisher et al., 2012)
head mesoderm
(Fisher et al., 2012)
inclusive hindgut primordium
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
posterior endoderm
(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
embryonic stage 11 -- 12
anterior midgut primordium
(Fisher et al., 2012)
head mesoderm
(Fisher et al., 2012)
hindgut proper primordium
(Fisher et al., 2012)
posterior midgut primordium
(Fisher et al., 2012)
salivary gland body primordium
(Fisher et al., 2012)
somatic muscle primordium

Comment: reported as muscle system primordium

(Fisher et al., 2012)
trunk visceral muscle primordium

Comment: reported as muscle system primordium

(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
embryonic stage 13 -- 16
dorsal pharyngeal muscle cell
(Fisher et al., 2012)
embryonic hindgut
(Fisher et al., 2012)
embryonic/larval fat body
(Fisher et al., 2012)
embryonic/larval midgut
(Fisher et al., 2012)
larval muscle system
(Fisher et al., 2012)
gastric caecum
(Fisher et al., 2012)
gonad
(Fisher et al., 2012)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in cytoplasm
inferred from direct assay
(Yu et al., 2018)
located_in cytosol
inferred from direct assay
(Miśkiewicz et al., 2011)
part_of elongator holoenzyme complex
inferred from direct assay
(Planelles-Herrero et al., 2022)
located_in synapse
inferred from direct assay
(Miśkiewicz et al., 2011)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Elp3 in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 1-3
  • Stages(s) 4-6
  • Stages(s) 7-8
  • Stages(s) 11-12
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 13 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 15 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Elp3
Transgenic constructs containing regulatory region of Elp3
Aberrations (Deficiencies and Duplications) ( 2 )
Inferred from experimentation ( 2 )
Gene disrupted in
Df(2L)Exel8011
(Ryder, 2004.4.26)
Gene partially disrupted in
Df(2L)Elp3Ex9
(Walker et al., 2011)
Inferred from location ( 3 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal
lethal (with Elp31)
lethal (with Elp32)
lethal (with Elp3Δ3)
lethal (with Elp3Δ4)
lethal - all die before end of larval stage, with Scer\GAL4da.PU
lethal - all die before end of P-stage, with Scer\GAL4hs.PB
lethal - all die before end of pupal stage
lethal - all die during embryonic stage, with Scer\GAL4Act5C.PI
lethal - all die during embryonic stage, with Scer\GAL4en.PU
lethal - all die during embryonic stage, with Scer\GAL4ptc.PU
lethal - all die during embryonic stage, with Scer\GAL4rho.PU
partially lethal - majority die | heat sensitive, with Scer\GAL4da.G32
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4elav.PU
viable, with Scer\GAL4hry.PU
viable, with Scer\GAL4Kr.PU
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
viable | heat sensitive, with Scer\GAL460IIA
viable | heat sensitive, with Scer\GAL4elav-C155
Sterility
Allele
female sterile, with Elp3Ex1
female sterile, with Elp3UAS.Tag:HA
Other Phenotypes
Allele
abnormal developmental rate
abnormal neuroanatomy
abnormal neuroanatomy | heat sensitive, with Scer\GAL4elav-C155
abnormal neurophysiology | third instar larval stage (with Elp3Δ3)
abnormal neurophysiology | third instar larval stage (with Elp3Δ4)
abnormal pain response | adult stage, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
abnormal sleep | heat sensitive, with Scer\GAL460IIA
increased rate of movement | heat sensitive, with Scer\GAL460IIA
increased rate of movement | heat sensitive, with Scer\GAL4elav-C155
melanotic mass phenotype
some die during pupal stage | heat sensitive, with Scer\GAL4da.G32
visible, with Scer\GAL4Bx-MS1096
visible, with Scer\GAL4pnr-MD237
Phenotype manifest in
Allele
cytoskeleton of presynaptic active zone (with Elp3Δ3)
cytoskeleton of presynaptic active zone (with Elp3Δ4)
embryonic/larval hemocyte
embryonic/larval hemocyte, with Scer\GAL4He.PZ
embryonic/larval hemocyte, with Scer\GAL4Pxn.PS
external sensory organ precursor cell, with Scer\GAL4neur-P72
external sensory organ precursor cell | somatic clone
leg disc
NMJ bouton, with Scer\GAL4elav-C155
photoreceptor neuron
salivary gland
spindle midzone, with Scer\GAL4neur-P72
trichogen cell, with Scer\GAL4pnr-MD237
type I bouton, with Scer\GAL4elav-C155
wing, with Scer\GAL4Bx-MS1096
wing disc
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (2)
Hsap\ELP3
14 of 14
Yes
Yes
 
1  
Hsap\RSAD1
1 of 14
No
Yes
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (1)
Rnor\Elp3
14 of 14
Yes
Yes
Mus musculus (laboratory mouse) (1)
Mmus\Elp3
13 of 14
Yes
Yes
Xenopus tropicalis (Western clawed frog) (2)
Xtro\elp3
11 of 13
Yes
Yes
Xtro\slc35f4
1 of 13
No
No
Danio rerio (Zebrafish) (2)
Drer\elp3
14 of 14
Yes
Yes
Drer\rsad1
1 of 14
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (1)
Cele\elpc-3
14 of 14
Yes
Yes
Anopheles gambiae (African malaria mosquito) (1)
Agam\AgaP_AGAP008300
12 of 12
Yes
Yes
Arabidopsis thaliana (thale-cress) (1)
Atha\ELO3
13 of 13
Yes
Yes
Saccharomyces cerevisiae (Brewer's yeast) (1)
Scer\ELP3
13 of 13
Yes
Yes
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\elp3
12 of 12
Yes
Yes
Escherichia coli (enterobacterium) (1)
Ecol\yhcC
5 of 11
Yes
Yes
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:Elp3. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    ELP3; elongator acetyltransferase complex subunit 3
    14 of 14
    612722
         
        Functional Complementation Data
        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
        Dmel gene
        Ortholog showing functional complementation
        Supporting References
        Elp3
        Hsap\ELP3
        (Miśkiewicz et al., 2011)
        Interactions
        Summary of Physical Interactions
        Summary of Genetic Interactions
        Interaction Browsers
        View in FlyBase Interactions Browser   View in MIST tool (external link)
        Please look at the allele data for full details of the genetic interactions
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        mbl
        suppressible
        Elp3
        (Vicente-Crespo et al., 2008)
        External Data
        Subunit Structure (UniProtKB)
        Component of the elongator complex composed of Elp1, Elp2, Elp3, Elp4, Elp5 and Elp6 (PubMed:36302967). The elongator complex associates with and stabilizes microtubules; efficient interaction requires the full complex (PubMed:36302967).
        (UniProt, Q9VQZ6 )
        Linkouts
        DroID - A comprehensive database of gene and protein interactions.
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Pathways
        Signaling Pathways (FlyBase)
        Metabolic Pathways
        FlyBase
        External Links
        FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel
        External Data
        Linkouts
        Class of Gene
        Genomic Location and Detailed Mapping Data
        Chromosome (arm)
        2L
        Recombination map
        2-12
        Cytogenetic map
        24F2-24F2
        Sequence location
        FlyBase Computed Cytological Location
        Cytogenetic map
        Evidence for location
        24F2-24F2
        Limits computationally determined from genome sequence between P{lacW}Tps1k08903&P{EP}morgueEP1184 and P{lacW}l(2)k10004k10004&P{EP}CG3036EP963
        Experimentally Determined Cytological Location
        Cytogenetic map
        Notes
        References
        Experimentally Determined Recombination Data
        Location

        2-12

        (FlyBase, 2016)

        2-13.5

        (Comeron et al., 2012)
        Left of (cM)
        Right of (cM)
        Notes
        Stocks and Reagents
        Stocks (12)
        Genomic Clones (23)
        cDNA Clones (6)
         

        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

        cDNA clones, fully sequenced
        BDGP DGC clones
        Other clones
        Drosophila Genomics Resource Center cDNA clones

        For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        RNAi and Array Information
        Linkouts
        DRSC - Results frm RNAi screens
        Antibody Information
        Laboratory Generated Antibodies
         

        polyclonal

        (Planelles-Herrero et al., 2022, Yu et al., 2018)
        Commercially Available Antibodies
         
        Cell Line Information
        Publicly Available Cell Lines
         
          Other Stable Cell Lines
           
          Other Comments
          Relationship to Other Genes
          Source for database merge of
          Additional comments
          Nomenclature History
          Source for database identify of

          Source for identity of: Elp3 CG15433

          (Zhu et al., 2007)
          Nomenclature comments
          Etymology
          Synonyms and Secondary IDs (14)
          Datasets (0)
          Study focus (0)
          Experimental Role
          Project
          Project Type
          Title
          Study result (0)
          Result
          Result Type
          Title
          External Crossreferences and Linkouts ( 37 )
          Sequence Crossreferences
          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
          UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
          UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
          Other crossreferences
          AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
          BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
          DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
          EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
          FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
          FlyMine - An integrated database for Drosophila genomics
          InterPro - A database of protein families, domains and functional sites
          KEGG Genes - Molecular building blocks of life in the genomic space.
          MARRVEL_MODEL - MARRVEL (model organism gene)
          Linkouts
          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
          DroID - A comprehensive database of gene and protein interactions.
          DRSC - Results frm RNAi screens
          Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
          FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
          FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel
          Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
          Flygut - An atlas of the Drosophila adult midgut
          iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
          MIST (protein-protein) - An integrated Molecular Interaction Database
          References (71)