FlyBase Gene Report: Dmel\mub

General Information

Symbol

Dmel\mub

Species

D. melanogaster

Name

mushroom-body expressed

Annotation Symbol

CG7437

Feature Type

protein_coding_gene

FlyBase ID

FBgn0262737

Gene Model Status

Current

Stock Availability

23 publicly available

Gene Summary

mushroom-body expressed (mub) encodes a protein involved in thermosensory behavior and regulation of alternative mRNA splicing. [Date last reviewed: 2019-09-26] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Interactive Fly

Also Known As

MRE17, l(3)04093

Key Links

Genomic Location

Cytogenetic map

78F4-79A4

Sequence location

3L:21,844,788..21,932,702 [+]

Recombination map

3-47

RefSeq locus

NT_037436 REGION:21844788..21932702

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (4 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables nucleic acid binding

inferred from electronic annotation with InterPro:IPR004087

(InterPro Project Members, 2004-)

enables RNA binding

inferred from electronic annotation with InterPro:IPR004088, InterPro:IPR036612

(InterPro Project Members, 2004-)

Biological Process (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in regulation of alternative mRNA splicing, via spliceosome

inferred from mutant phenotype

(Park et al., 2004)

inferred from high throughput mutant phenotype

(Park et al., 2004)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

involved_in regulation of alternative mRNA splicing, via spliceosome

inferred from biological aspect of ancestor with PANTHER:PTN008497135

(GO Reference Genome Project, 2011-)

Cellular Component (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

located_in nucleus

inferred by curator from GO:0000381

(Park et al., 2004)

Gene Group (FlyBase)

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

mushroom-body expressed (mub) encodes a protein involved in thermosensory behavior and regulation of alternative mRNA splicing. [Date last reviewed: 2019-09-26]

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\mub for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry M9NEH9)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated

Gene model reviewed during 5.45

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Gene model reviewed during 5.46

Stage-specific extension of 3' UTRs observed during embryogenesis (FBrf0215804); all variants may not be annotated.

Gene model reviewed during 6.02

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

mub-RA

FBtr0078468

NM_079484

3437

386

mub-RC

FBtr0078470

NM_206423

9374

364

mub-RD

FBtr0111017

NM_001043154

11975

539

mub-RE

FBtr0301364

NM_001170022

3441

557

mub-RF

FBtr0304980

NM_001259944

3553

557

mub-RG

FBtr0304981

NM_168946

3468

359

mub-RH

FBtr0304982

NM_001259947

3690

433

mub-RI

FBtr0304983

NM_001259945

3387

539

mub-RK

FBtr0304984

NM_001259946

3489

573

mub-RL

FBtr0332736

NM_001275269

2968

368

mub-RM

FBtr0333222

NM_001275268

9471

359

mub-RN

FBtr0346820

NM_001316446

9527

415

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

mub-PA

FBpp0078122

40.6

386

8.32

FBpp0089422

38.5

364

8.56

FBpp0110316

54.5

539

8.89

FBpp0290578

56.2

557

8.72

FBpp0293517

56.2

557

8.72

FBpp0293518

37.9

359

8.67

FBpp0293519

45.4

433

8.11

FBpp0293520

54.3

539

9.03

FBpp0293521

58.1

573

8.48

FBpp0304982

38.8

368

8.56

FBpp0305424

37.9

359

8.67

FBpp0312395

43.6

415

8.33

A0A0S0WH03

NP_001303375

ALI30491

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

359 aa isoforms: mub-PG, mub-PM

557 aa isoforms: mub-PE, mub-PF

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mub using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

mub_1
mub_2

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-1.01

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 9 -- 17

organism

Comment: extended 3' UTR isoform

(Hilgers et al., 2011)

embryonic stage 13 -- 16

embryonic brain

(Fisher et al., 2012)

embryonic central brain

(Fisher et al., 2012)

mushroom body primordium

Comment: reported as embryonic central brain mushroom body

(Fisher et al., 2012)

larval ventral nerve cord

(Fisher et al., 2012)

Additional Descriptive Data

Isoforms of mub with extended 3' UTRs appear later in embryogenesis.

(Hilgers et al., 2011)

Isoform-specific expression patterns are observed. Sex-specific expression of alternative transcripts observed.

(Telonis-Scott et al., 2009)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\mub in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\mub

View exonic expression by tissue for Dmel\mub

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0262737

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

40436/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0262737

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0014362

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0262737

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG7437

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 47 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 6 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of mub

Transgenic constructs containing regulatory region of mub

Aberrations (Deficiencies and Duplications) ( 4 )

Inferred from experimentation ( 4 )

Gene not disrupted in

Df(3L)Pc

(BDGP Project Members, 1994-1999)

Df(3L)Pc-MK

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Gene disrupted in

Df(3L)BSC284

(Christensen et al., 2007.5.8)

Df(3L)Exel6137

(Ryder, 2004.4.26)

Inferred from location ( 5 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal | female limited, with Scer\GAL4^dome-PG14

mub^HMC04199

lethal | recessive

lethal - all die before end of pupal stage, with Scer\GAL4^pnr-MD237

mub^GD12242

partially lethal - majority die | recessive

mub^GTDZ-1

viable

mub^CC01995

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

mub^GD12242

viable, with Scer\GAL4^tin.CΔ4

mub^GD12242

Other Phenotypes

Allele

abnormal eclosion (with Df(3L)Exel6137)

mub⁰⁴⁰⁹³

abnormal flight, with Scer\GAL4^Act88F.PB

mub^KK108209

abnormal locomotor behavior (with Df(3L)Exel6137)

mub⁰⁴⁰⁹³

abnormal locomotor behavior | adult stage

mub^BG00043

abnormal locomotor behavior | adult stage | male limited

mub^BG00041

abnormal locomotor rhythm, with Scer\GAL4^tim.PE

mub^KK108209

abnormal starvation stress response

abnormal starvation stress response | male limited

mub^BG00041

abnormal temperature response

flightless, with Scer\GAL4^Mef2.PR

mub^GD12242

flightless (with Df(3L)Exel6137)

mub⁰⁴⁰⁹³

long lived

long lived | female limited

mub^BG00039

long lived | male limited

short lived | heat sensitive, with Scer\GAL4^tin.CΔ4

mub^GD12242

some die during pupal stage, with Scer\GAL4^pnr-MD237

mub^GD12242

Phenotype manifest in

Allele

dorsal appendage, with Scer\GAL4^{VP16.mat.αTub67C}

mub^UASp.cGa

egg, with Scer\GAL4^{VP16.mat.αTub67C}

mub^UASp.cGa

egg chorion, with Scer\GAL4^{VP16.mat.αTub67C}

mub^UASp.cGa

embryonic/larval hemocyte | third instar larval stage, with Scer\GAL4^Pxn.PS

mub^EY11687

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (17)

Hsap\PCBP3

13 of 14

Yes

Hsap\PCBP1

11 of 14

Yes

Hsap\PCBP4

11 of 14

Yes

Hsap\PCBP2

10 of 14

Yes

3 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (16)

Rnor\Pcbp3

13 of 14

Yes

Rnor\Pcbp2

11 of 14

Yes

Rnor\Pcbp4

11 of 14

Yes

3 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (16)

Mmus\Pcbp3

13 of 14

Yes

Mmus\Pcbp1

11 of 14

Yes

Mmus\Pcbp2

11 of 14

Yes

Mmus\Pcbp4

11 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (17)

Xtro\pcbp1

10 of 13

Yes

Xtro\h1-8

9 of 13

Yes

Xtro\pcbp2

9 of 13

Yes

Xtro\pcbp3

9 of 13

Yes

Xtro\aipl1

1 of 13

Yes

Xtro\aurkaip1

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Danio rerio (Zebrafish) (19)

Drer\pcbp3

11 of 14

Yes

Drer\pcbp2

10 of 14

Yes

Drer\pcbp4

10 of 14

Yes

Drer\igf2bp3

3 of 14

Drer\zgc:110045

3 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Caenorhabditis elegans (Nematode, roundworm) (9)

Cele\pes-4

10 of 14

Yes

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Anopheles gambiae (African malaria mosquito) (7)

Agam\AgaP_AGAP004942

11 of 12

Yes

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (18)

Atha\AT1G14170

7 of 13

Yes

Atha\AT4G18375

7 of 13

Yes

Atha\AT5G15270

6 of 13

Yes

Atha\AT5G46190

6 of 13

Yes

Atha\AT1G51580

5 of 13

Atha\FLK

5 of 13

Yes

Atha\HEN4

5 of 13

Atha\PEP

5 of 13

Yes

Atha\RCF3

5 of 13

Yes

Atha\AT2G22600

3 of 13

Yes

Atha\AT2G03110

2 of 13

Yes

2 of 13

1 of 13

1 of 13

1 of 13

Yes

Atha\AT4G10070

1 of 13

Atha\AT5G06770

1 of 13

Yes

Atha\BTR1L

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (3)

Scer\PBP2

10 of 13

Yes

Scer\HEK2

5 of 13

Yes

Scer\SCP160

1 of 13

Schizosaccharomyces pombe (Fission yeast) (2)

Spom\rnc1

8 of 12

Yes

Spom\usp108

1 of 12

Yes

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:mub. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (6)

HnRNP-K

7 of 13

Imp

4 of 13

Psi

2 of 13

CG7878

1 of 13

Dp1

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 4 )

Allele

Disease

Interaction

References

mub⁰⁴⁰⁹³

exacerbates olivopontocerebellar atrophy

modeled by Hsap\ATXN1^82Q.UAS

(Branco et al., 2008)

mub^EP3623

ameliorates autosomal dominant cerebellar ataxia

modeled by Hsap\ATXN1^82Q.UAS

(Fernandez-Funez et al., 2000)

modeled by Hsap\ATXN1^30Q.UAS

(Fernandez-Funez et al., 2000)

exacerbates autosomal dominant cerebellar ataxia

modeled by Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}

(Latouche et al., 2007)

exacerbates Huntington's disease

modeled by Hsap\HTT^{128Q.1-336.UAS}

(Branco et al., 2008)

ameliorates olivopontocerebellar atrophy

modeled by Hsap\ATXN1^82Q.UAS

(Branco et al., 2008)

mub^EP3108

exacerbates Alzheimer's disease

modeled by Hsap\APP^{Aβ42.GMR.Tag:SS(rPENK)}

(Cao et al., 2008)

ameliorates Huntington's disease

modeled by Hsap\HTT^Q93.ex1.UAS

(Cao et al., 2008)

ameliorates tauopathy

modeled by Hsap\MAPT^UAS.cWa

(Cao et al., 2008)

mub^KK108209

ameliorates C9orf72 frontotemporal dementia and/or amyotrophic lateral sclerosis

modeled by Zzzz\poly-GR^50.UAS.EGFP

(Lee et al., 2016)

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

PCBP3; poly(rC) binding protein 3

13 of 14

608502

PCBP1; poly(rC) binding protein 1

11 of 14

601209

PCBP4; poly(rC) binding protein 4

11 of 14

608503

PCBP2; poly(rC) binding protein 2

10 of 14

601210

IGF2BP3; insulin like growth factor 2 mRNA binding protein 3

3 of 14

608259

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

mub - Slmap

experimental knowledge based

(Guruharsha et al., 2011)

mub - geminin

experimental knowledge based

(Guruharsha et al., 2011)

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Imp

enhanceable

mub

(Geng and MacDonald, 2007)

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0262737

MIST (protein-protein) - An integrated Molecular Interaction Database

40436

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-47

Cytogenetic map

78F4-79A4

Sequence location

3L:21,844,788..21,932,702 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

78F4-79A4

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

79B1-79B2

(determined by in situ hybridisation)

(Lukacsovich et al., 2001, Spradling et al., 1999)

79B1-79B3

(Grams, 1996.7.15)

79B-79B

(determined by in situ hybridisation)

(Grams and Korge, 1998)

66A1-66A2

(BDGP Project Members, 1994-1999)

Experimentally Determined Recombination Data

Location

3-47

(FlyBase, 2016)

3-44.0

(Comeron et al., 2012)

(Grams, 1996.7.15)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (23)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

12403

w¹¹¹⁸; P{GT1}mub^BG00074

85560

w¹¹¹⁸; PBac{RB}mub^e01971

63499

w¹¹¹⁸; PBac{IT.GAL4}mub^0756-G4

65484

w¹¹¹⁸; PBac{IT.GAL4}mub^1162-G4

77674

w¹¹¹⁸; PBac{IT.GAL4}mub^4075-G4

34474

y¹ w^*; Mi{MIC}mub^MI02309

38123

y¹ w^*; Mi{MIC}mub^MI03237

11114

11592

123518

w¹¹¹⁸; P{RS3}mub^CB-5230-3

VDRC

v105495

P{KK108209}VIE-260B

v28024

w¹¹¹⁸; P{GD12242}v28024

More stocks available...

Genomic Clones (63)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (159)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0262737

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

New stable cell line derived from S2-unspecified : S2 cell lines expressing circCG32369, circMCPH1, circeIF5B, circrl, circPde11, circCG17715, circzfh2, circTao, circcrol, circdrn, circMeltrin, circpxb, circfru, circdati, circstw, circSarm, circStim, circCG2991, circPvr, circHil, circmub, circsxc, circbnl, and circCG9743 were created. The author reports new stable cell lines S2-circMCPH1, S2-circCG32369, S2-Flag-Ddx56 , and S2-Flag-gw.
(Su et al., 2024)

Other Comments

mub has been cloned and sequenced, and its expression pattern has been analysed.

(Grams and Korge, 1998)

Relationship to Other Genes

Source for database merge of

Source for merge of: mub l(3)04093

(Spradling et al., 1999)

Source for merge of: mub anon-WO0172774.33 anon-WO0172774.35 anon-WO0172774.36 anon-WO0172774.37

(FlyBase, 1996-)

Source for merge of: mub MRE17

(FlyBase Genome Annotators, 2011)

Additional comments

MRE17 is part of the 3' UTR of mub.

(FlyBase Genome Annotators, 2011)

MRE17 corresponds to a portion of the 3' UTR of mub.

(FlyBase Genome Annotators, 2011)

Source for merge of mub anon-WO0172774.33 anon-WO0172774.35 anon-WO0172774.36 anon-WO0172774.37 was sequence comparison ( date:051113 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (18)

Reported As

Symbol Synonym

CG7437

(Brooks et al., 2015, Hosono et al., 2015, Mandilaras and Missirlis, 2012, Ni et al., 2011.7.19, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Quinones-Coello, 2007, McIntyre et al., 2006, Levis, 2001.2.27)

MRE17

(FlyBase Genome Annotators, 2011, Kageyama, 2007.2.28, Inagaki et al., 2005)

MUB

(Damulewicz et al., 2025, Sofola et al., 2007)

Mub

(Jevitt et al., 2020, Sun et al., 2012, Venables et al., 2012, Christensen et al., 2007.5.8, Betz and Darnell, 2006, Dierick and Greenspan, 2006, Branco et al., 2004)

anon-WO0172774.33

anon-WO0172774.35

anon-WO0172774.36

anon-WO0172774.37

l(3)04093

(Meister and Braun, 1995.10, BDGP Project Members, 1994-1999)

l(3)j6B10

l(3)j8B3

mub

(Dyson et al., 2025, Jones et al., 2025, Floc'hlay et al., 2023, Corrales et al., 2022, Joseph et al., 2022, Bilder et al., 2021, Kao et al., 2021, Klann et al., 2021, Pang et al., 2021, Patel and Talbert, 2021, Wu et al., 2021, Sapiro et al., 2020, Fingerhut et al., 2019, Gao et al., 2019, Hall et al., 2019, Wang et al., 2018, Hsu and Drummond-Barbosa, 2017, Lee et al., 2017, Clandinin and Owens, 2016-, Lee et al., 2016, Ou et al., 2016, Brooks et al., 2015, Fear et al., 2015, Stoiber et al., 2015, Ashwal-Fluss et al., 2014, Lye et al., 2014, Oas et al., 2014, Mandilaras and Missirlis, 2012, Smibert et al., 2012, FlyBase Genome Annotators, 2011, Hilgers et al., 2011, Magwire et al., 2010, Skora and Spradling, 2010, Telonis-Scott et al., 2009, Branco et al., 2008, Cao et al., 2008, Stofanko et al., 2008, Blard et al., 2007, Buszczak et al., 2007, Geng and MacDonald, 2007, Latouche et al., 2007, Quinones-Coello, 2007, Sofola et al., 2007, Zhang et al., 2007, Jang et al., 2006, McIntyre et al., 2006)

Name Synonyms

Mushroom-body expressed

(Branco et al., 2008)

mRNA-like ncRNA in embryogenesis 17

mushroom bodies

(Grams and Korge, 1995)

mushroom body expressed

(Magwire et al., 2010, Geng and MacDonald, 2007)

mushroom-body expressed

(Blard et al., 2007, Grams and Korge, 1998)

poly (rC) binding protein

(Mandilaras and Missirlis, 2012)

Secondary FlyBase IDs

FBgn0014362
FBgn0010834
FBgn0011394
FBgn0011408
FBgn0046394
FBgn0046395
FBgn0046396
FBgn0046397
FBgn0086548

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 101 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

40436

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

M9NEH9

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

M9NEH9

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0262737

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

40436/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0262737

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0262737

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG7437

MARRVEL_MODEL - MARRVEL (model organism gene)

40436

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0262737

DroID - A comprehensive database of gene and protein interactions.

FBgn0262737

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

mub_1
mub_2

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0014362

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0262737

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG7437

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0262737

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC000237

MIST (protein-protein) - An integrated Molecular Interaction Database

40436

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

References (137)

The following external sites may use different assemblies or annotations than FlyBase.

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