FlyBase Gene Report: Dmel\Octβ1R

General Information

Symbol

Dmel\Octβ1R

Species

D. melanogaster

Name

Octopamine β1 receptor

Annotation Symbol

CG6919

Feature Type

protein_coding_gene

FlyBase ID

FBgn0038980

Gene Model Status

Current

Stock Availability

80 publicly available

Gene Summary

Autoreceptor for octopamine, which is a neurotransmitter, neurohormone, and neuromodulator in invertebrates (PubMed:15816867, PubMed:22553037). Negatively regulates synaptic growth by activating the inhibitory G protein Galphao and limiting cAMP production (PubMed:22553037). Antagonizes the action of Octbeta2R which stimulates synaptic growth (PubMed:22553037). (UniProt, Q9VCZ3)

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
UniProtKB
Interactive Fly

Also Known As

oa2, octopamine receptor 2, DmOctβ1R, OctBeta1

Key Links

Genomic Location

Cytogenetic map

94B1-94B2

Sequence location

3R:22,497,215..22,520,078 [+]

Recombination map

3-75

RefSeq locus

NT_033777 REGION:22497215..22520078

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (11 terms)

Molecular Function (3 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables octopamine receptor activity

inferred from direct assay

(Balfanz et al., 2005, Maqueira et al., 2005)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

enables adrenergic receptor activity

inferred from electronic annotation with InterPro:IPR002233

(InterPro Project Members, 2004-)

enables G protein-coupled receptor activity

inferred from electronic annotation with InterPro:IPR000276

(InterPro Project Members, 2004-)

enables octopamine receptor activity

inferred from biological aspect of ancestor with PANTHER:PTN001206597

(GO Reference Genome Project, 2011-)

Biological Process (6 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway

inferred from direct assay

(Maqueira et al., 2005)

inferred from direct assay

(Balfanz et al., 2005)

involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway

inferred from direct assay

(Balfanz et al., 2005)

involved_in negative regulation of synaptic assembly at neuromuscular junction

inferred from mutant phenotype

(Koon and Budnik, 2012)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in adenylate cyclase-activating adrenergic receptor signaling pathway

inferred from biological aspect of ancestor with PANTHER:PTN001205212

(GO Reference Genome Project, 2011-)

involved_in G protein-coupled receptor signaling pathway

inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR002233

(InterPro Project Members, 2004-)

involved_in positive regulation of MAPK cascade

inferred from biological aspect of ancestor with PANTHER:PTN001205212

(GO Reference Genome Project, 2011-)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

located_in plasma membrane

inferred from direct assay

(Maqueira et al., 2005)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

located_in membrane

inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR002233, InterPro:IPR017452

(InterPro Project Members, 2004-)

non-traceable author statement

(Balfanz et al., 2005)

is_active_in plasma membrane

inferred from biological aspect of ancestor with PANTHER:PTN002798190

(GO Reference Genome Project, 2011-)

located_in plasma membrane

inferred by curator from GO:0004989

(Balfanz et al., 2005)

Gene Group (FlyBase)

OCTOPAMINE RECEPTORS

Protein Family (UniProt)

Belongs to the G-protein coupled receptor 1 family. (Q9VCZ3)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

OCTOPAMINE RECEPTORS -: Octopamine receptors belong to the Class A GPCR family. In mammalian systems, octopamine is a member of the trace amines, but in insects octopamine and tyramine are thought to be the main neurotransmitters. (Adapted from PMID:17088868, FBrf0214056 and FBrf0190865).

Protein Function (UniProtKB)

(UniProt, Q9VCZ3)

Summary (Interactive Fly)

G-protein coupled receptor - autoregulatory control of synaptic and behavioral plasticity at excitatory synapses - control of appetitive motivation

Interactive Fly

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Octβ1R for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VCZ3)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.44

Gene model reviewed during 5.45

Gene model reviewed during 5.47

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Octβ1R-RA

FBtr0084260

NM_142800

2258

508

Octβ1R-RB

FBtr0100322

NM_001038975

2426

421

Octβ1R-RC

FBtr0301484

NM_001170219

1949

428

Octβ1R-RE

FBtr0331930

NM_001275914

5007

508

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Octβ1R-PA

FBpp0083653

56.9

508

8.82

FBpp0099727

47.2

421

8.77

NP_001034064

ABC66185

Octβ1R-PC

FBpp0290699

47.9

428

8.57

FBpp0304263

56.9

508

8.82

Q9VCZ3

NP_001262843

AGB96223

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

508 aa isoforms: Octβ1R-PA, Octβ1R-PE

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Octβ1R using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Octbeta1R_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.74

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 13 -- 16

Bolwig organ

(Fisher et al., 2012)

dorsal sensory complex proper primordium

Comment: reported as dorsal/lateral sensory complexes

(Fisher et al., 2012)

embryonic brain

(Fisher et al., 2012)

embryonic head sensory system

(Fisher et al., 2012)

larval ventral midline glial cell

(Fisher et al., 2012)

ventral midline of embryo

(Fisher et al., 2012)

larval ventral nerve cord

(Fisher et al., 2012)

ventral sensory complex primordium

(Fisher et al., 2012)

RT-PCR

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

larval brain

(El-Kholy et al., 2015)

adult stage

adult brain

(El-Kholy et al., 2015)

adult muscle system

(El-Kholy et al., 2015)

adult tracheal section

(El-Kholy et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in plasma membrane

inferred from direct assay

(Maqueira et al., 2005)

Expression Deduced from Reporters

Reporter: Mi{Trojan-GAL4.2}Octβ1R^{MI05807-TG4.2}

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult Kenyon cell

(McKinney et al., 2020)

larval antennal lobe tyraminergic neuron | subset

(McKinney et al., 2020)

adult octopaminergic subesophageal VM neuron | subset

(McKinney et al., 2020)

adult octopaminergic neuron | subset

(McKinney et al., 2020)

Reporter: P{GMR19H07-GAL4}

Stage

Tissue/Position (including subcellular localization)

Reference

P-stage

antennal lobe commissural pioneer interneuron

(Kaur et al., 2019)

antennal lobe lateral commissural pioneer interneuron

(Kaur et al., 2019)

antennal lobe medial commissural pioneer interneuron

(Kaur et al., 2019)

prepupal stage P4 -- pupal stage P6

antennal lobe commissural pioneer interneuron

(Kaur et al., 2019)

adult stage

adult posterior lateral protocerebrum-dorsal accessory calyx projection neuron | subset

(Li et al., 2020)

neuron of adult brain

(Li et al., 2020)

Reporter: P{GMR20C11-GAL4}

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage

type III bouton

(Koon and Budnik, 2012)

motor neuron | subset

(Koon and Budnik, 2012)

larval brain | restricted

(Koon and Budnik, 2012)

neuron | subset of larval ventral nerve cord

(Koon and Budnik, 2012)

eye-antennal disc | restricted

(Koon and Budnik, 2012)

imaginal disc | restricted

(Koon and Budnik, 2012)

Reporter: P{GMR20E11-GAL4}

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage

motor neuron

• type Ib terminal bouton | faint

(Koon and Budnik, 2012)

larval brain | restricted

(Koon and Budnik, 2012)

neuron | subset of larval ventral nerve cord

(Koon and Budnik, 2012)

Reporter: P{GMR21E03-GAL4}

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage

motor neuron

• type Is terminal bouton

(Koon and Budnik, 2012)

motor neuron

• type II terminal bouton

(Koon and Budnik, 2012)

larval brain | restricted

(Koon and Budnik, 2012)

octopaminergic neuron | subset of larval ventral nerve cord

(Koon and Budnik, 2012)

imaginal disc | restricted

(Koon and Budnik, 2012)

Reporter: P{Octβ1R-GAL4.E}

Stage

Tissue/Position (including subcellular localization)

Reference

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Octβ1R in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Octβ1R

View exonic expression by tissue for Dmel\Octβ1R

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0038980

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

42652/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0038980

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0038980

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0038980

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG6919

Flygut - An atlas of the Drosophila adult midgut

FBgn0038980

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\Octβ1R

Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 22 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 12 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Octβ1R

Transgenic constructs containing regulatory region of Octβ1R

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(3R)Exel6191

(Ryder, 2004.4.26)

Inferred from location ( 6 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Octβ1R^GD701

viable, with Scer\GAL4^Mef2.PR

Octβ1R^GD701

viable, with Scer\GAL4^pnr-MD237

Octβ1R^GD701

viable, with Scer\GAL4^tin.CΔ4

Octβ1R^GD701

Sterility

Allele

fertile

Octβ1R^f02819

Other Phenotypes

Allele

abnormal locomotor behavior | third instar larval stage

Octβ1R¹

abnormal locomotor behavior | third instar larval stage (with Df(3R)Exel6191)

Octβ1R¹

abnormal neuroanatomy | third instar larval stage

Octβ1R¹

abnormal neuroanatomy | third instar larval stage, with Scer\GAL4^BG439

Octβ1R^KK102153

abnormal neuroanatomy | third instar larval stage, with Scer\GAL4^futsch-C380

Octβ1R^KK102153

abnormal neuroanatomy | third instar larval stage, with Scer\GAL4^Tdc2.PC

Octβ1R^KK102153

abnormal neuroanatomy | third instar larval stage (with Df(3R)Exel6191)

Octβ1R¹

abnormal sleep | adult stage

Octβ1R^attP

Phenotype manifest in

Allele

embryonic/larval neuromuscular junction | third instar larval stage

Octβ1R¹

embryonic/larval neuromuscular junction | third instar larval stage, with Scer\GAL4^Tdc2.PC

Octβ1R^KK102153

embryonic/larval neuromuscular junction | third instar larval stage (with Df(3R)Exel6191)

Octβ1R¹

type I bouton | increased number | third instar larval stage

Octβ1R¹

type I bouton | increased number | third instar larval stage, with Scer\GAL4^BG439

Octβ1R^KK102153

type I bouton | increased number | third instar larval stage, with Scer\GAL4^futsch-C380

Octβ1R^KK102153

type I bouton | increased number | third instar larval stage (with Df(3R)Exel6191)

Octβ1R¹

type II bouton | increased number | third instar larval stage

Octβ1R¹

type II bouton | increased number | third instar larval stage, with Scer\GAL4^Tdc2.PC

Octβ1R^KK102153

type II bouton | increased number | third instar larval stage (with Df(3R)Exel6191)

Octβ1R¹

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (184)

Hsap\HTR4

7 of 14

Yes

Hsap\ADRB1

5 of 14

Yes

Hsap\ADRB2

4 of 14

Hsap\ADRB3

4 of 14

Yes

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\AVPR1B

1 of 14

Yes

Hsap\AVPR2

1 of 14

Hsap\BDKRB1

1 of 14

Yes

Hsap\BDKRB2

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\CCR2

1 of 14

Yes

Hsap\CCR3

1 of 14

Yes

Hsap\CCR4

1 of 14

Yes

Hsap\CCR5

1 of 14

Yes

Hsap\CCR8

1 of 14

Yes

Hsap\CCR9

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\CNR2

1 of 14

Yes

Hsap\CXCR4

1 of 14

Yes

Hsap\CXCR5

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\EDNRB

1 of 14

Yes

Hsap\F2RL2

1 of 14

Yes

Hsap\FPR2

1 of 14

Yes

Hsap\FPR3

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\GPR3

1 of 14

Yes

Hsap\GPR4

1 of 14

Yes

Hsap\GPR6

1 of 14

Yes

Hsap\GPR12

1 of 14

Yes

Hsap\GPR17

1 of 14

Hsap\GPR19

1 of 14

Yes

Hsap\GPR21

1 of 14

Hsap\GPR22

1 of 14

Yes

Hsap\GPR26

1 of 14

Yes

Hsap\GPR27

1 of 14

Yes

Hsap\GPR34

1 of 14

Yes

Hsap\GPR39

1 of 14

Hsap\GPR45

1 of 14

Yes

Hsap\GPR50

1 of 14

Hsap\GPR52

1 of 14

Hsap\GPR61

1 of 14

Yes

Hsap\GPR62

1 of 14

Yes

Hsap\GPR63

1 of 14

Yes

Hsap\GPR68

1 of 14

Yes

Hsap\GPR78

1 of 14

Yes

Hsap\GPR83

1 of 14

Hsap\GPR84

1 of 14

Hsap\GPR85

1 of 14

Yes

Hsap\GPR101

1 of 14

Hsap\GPR119

1 of 14

Yes

Hsap\GPR135

1 of 14

Yes

Hsap\GPR148

1 of 14

Hsap\GPR161

1 of 14

Yes

Hsap\GPR173

1 of 14

Yes

Hsap\GPR176

1 of 14

Yes

Hsap\GPR182

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\LPAR2

1 of 14

Yes

Hsap\LPAR3

1 of 14

Yes

Hsap\LPAR4

1 of 14

Hsap\MC1R

1 of 14

Yes

Hsap\MC2R

1 of 14

Yes

Hsap\MC3R

1 of 14

Yes

Hsap\MC4R

1 of 14

Yes

Hsap\MC5R

1 of 14

Yes

Hsap\MCHR1

1 of 14

Hsap\MCHR2

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\OR4C6

1 of 14

Yes

Hsap\OR4C13

1 of 14

Yes

Hsap\OR4Q2

1 of 14

Yes

Hsap\OR4S1

1 of 14

Yes

Hsap\OR6S1

1 of 14

Yes

Hsap\OR14I1

1 of 14

Yes

Hsap\OXTR

1 of 14

Yes

Hsap\PROKR1

1 of 14

Yes

Hsap\PROKR2

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\S1PR2

1 of 14

Yes

Hsap\S1PR3

1 of 14

Yes

Hsap\S1PR4

1 of 14

Yes

Hsap\S1PR5

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (112)

Rnor\Htr4

7 of 14

Yes

Rnor\Adrb1

6 of 14

Yes

Rnor\Adrb2

5 of 14

Yes

Rnor\Adrb3

5 of 14

Yes

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Avpr1b

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Gpr3

1 of 14

Yes

Rnor\Gpr17

1 of 14

Yes

Rnor\Gpr19

1 of 14

Yes

Rnor\Gpr21

1 of 14

Rnor\Gpr22

1 of 14

Yes

Rnor\Gpr26

1 of 14

Yes

Rnor\Gpr27

1 of 14

Yes

Rnor\Gpr34

1 of 14

Yes

Rnor\Gpr45

1 of 14

Yes

Rnor\Gpr50

1 of 14

Yes

Rnor\Gpr61

1 of 14

Yes

Rnor\Gpr62

1 of 14

Yes

Rnor\Gpr63

1 of 14

Yes

Rnor\Gpr83

1 of 14

Rnor\Gpr85

1 of 14

Yes

Rnor\Gpr101

1 of 14

Yes

Rnor\Gpr119

1 of 14

Yes

Rnor\Gpr135

1 of 14

Yes

Rnor\Gpr161

1 of 14

Yes

Rnor\Gpr173

1 of 14

Yes

Rnor\Gpr182

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Mlnr

1 of 14

Rnor\Mtnr1a

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Olr641

1 of 14

Yes

Rnor\Olr650

1 of 14

Yes

Rnor\Olr686

1 of 14

Yes

Rnor\Olr693

1 of 14

Yes

Rnor\Olr742

1 of 14

Yes

Rnor\Olr1405

1 of 14

Yes

Rnor\Olr1646

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Taar8b

1 of 14

Yes

Rnor\Taar8c

1 of 14

Yes

Rnor\Tacr2

1 of 14

Rnor\Trhr

1 of 14

Mus musculus (laboratory mouse) (102)

Mmus\Adrb1

6 of 14

Yes

Mmus\Htr4

6 of 14

Yes

Mmus\Adrb2

5 of 14

Yes

Mmus\Adrb3

5 of 14

Yes

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Mmus\Cnr2

1 of 14

Yes

Mmus\Drd2

1 of 14

Mmus\Drd3

1 of 14

Mmus\Drd4

1 of 14

Yes

Mmus\Galr2

1 of 14

Mmus\Gnrhr

1 of 14

Mmus\Gpbar1

1 of 14

Yes

Mmus\Gpr3

1 of 14

Yes

Mmus\Gpr17

1 of 14

Yes

Mmus\Gpr19

1 of 14

Yes

Mmus\Gpr21

1 of 14

Mmus\Gpr22

1 of 14

Yes

Mmus\Gpr26

1 of 14

Yes

Mmus\Gpr27

1 of 14

Yes

Mmus\Gpr34

1 of 14

Yes

Mmus\Gpr45

1 of 14

Yes

Mmus\Gpr50

1 of 14

Mmus\Gpr52

1 of 14

Mmus\Gpr61

1 of 14

Yes

Mmus\Gpr62

1 of 14

Yes

Mmus\Gpr63

1 of 14

Yes

Mmus\Gpr83

1 of 14

Mmus\Gpr85

1 of 14

Yes

Mmus\Gpr101

1 of 14

Yes

Mmus\Gpr119

1 of 14

Yes

Mmus\Gpr135

1 of 14

Yes

Mmus\Gpr161

1 of 14

Yes

Mmus\Gpr173

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Mmus\Olfr53

1 of 14

Yes

Mmus\Olfr61

1 of 14

Yes

Mmus\Olfr142

1 of 14

Yes

Mmus\Olfr366

1 of 14

Yes

Mmus\Olfr1189

1 of 14

Yes

Mmus\Olfr1232

1 of 14

Yes

Mmus\Olfr1377

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (137)

Xtro\adrb2

4 of 13

Yes

Xtro\htr4

4 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\avpr2

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\calhm4

1 of 13

Yes

Xtro\cbwd1.1

1 of 13

Xtro\ccr3

1 of 13

Yes

Xtro\ccr9

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\f2rl2

1 of 13

Yes

Xtro\f2rl3

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\gpr6

1 of 13

Yes

Xtro\gpr12

1 of 13

Yes

Xtro\gpr22

1 of 13

Yes

Xtro\gpr27

1 of 13

Yes

Xtro\gpr65

1 of 13

Yes

Xtro\gpr78

1 of 13

Yes

Xtro\gpr83

1 of 13

Xtro\gpr85

1 of 13

Yes

Xtro\gpr119

1 of 13

Yes

Xtro\gpr148

1 of 13

Xtro\gpr161

1 of 13

Yes

Xtro\gpr173

1 of 13

Yes

Xtro\gpr176

1 of 13

Yes

Xtro\grpr

1 of 13

Xtro\hrh4.b2

1 of 13

Xtro\hrh4.d1

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\LOC100489992

1 of 13

Xtro\LOC100491885

1 of 13

Xtro\LOC100495677

1 of 13

Yes

Xtro\LOC100496229

1 of 13

Yes

Xtro\LOC100498398

1 of 13

Yes

Xtro\LOC101732366

1 of 13

Xtro\LOC101733812

1 of 13

Yes

Xtro\LOC101733830

1 of 13

Yes

Xtro\LOC101734771

1 of 13

Xtro\LOC105946838

1 of 13

Xtro\LOC116411706

1 of 13

Yes

Xtro\lpar1

1 of 13

Yes

Xtro\lpar3

1 of 13

Yes

Xtro\ltb4r

1 of 13

Xtro\mc2r

1 of 13

Yes

Xtro\mc4r

1 of 13

Yes

Xtro\mc5r

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\opn5

1 of 13

Xtro\opn8

1 of 13

Xtro\opnpl [provisonal]

1 of 13

Xtro\oprk1

1 of 13

Xtro\p2ry1

1 of 13

Yes

Xtro\prlhr

1 of 13

Xtro\ptger3

1 of 13

Xtro\qrfprl2.2

1 of 13

Yes

Xtro\qrfpr

1 of 13

Yes

Xtro\rho

1 of 13

Yes

Xtro\rrh

1 of 13

Xtro\s1pr1

1 of 13

Yes

Xtro\s1pr5

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\tmtops

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Danio rerio (Zebrafish) (203)

Drer\htr4

6 of 14

Yes

Drer\adrb1

5 of 14

Yes

Drer\adrb3b

5 of 14

Yes

Drer\adrb3a

4 of 14

Yes

Drer\si:dkey-247m21.3

4 of 14

Yes

3 of 14

3 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\cnr2

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\gpr22a

1 of 14

Yes

Drer\gpr22b

1 of 14

Yes

Drer\gpr26

1 of 14

Yes

Drer\gpr27

1 of 14

Yes

Drer\gpr45

1 of 14

Yes

Drer\gpr52

1 of 14

Drer\gpr61

1 of 14

Yes

Drer\gpr61l

1 of 14

Yes

Drer\gpr63

1 of 14

Yes

Drer\gpr65

1 of 14

Yes

Drer\gpr78a

1 of 14

Yes

Drer\gpr78b

1 of 14

Yes

Drer\gpr85

1 of 14

Yes

Drer\gpr101

1 of 14

Yes

Drer\gpr135

1 of 14

Yes

Drer\gpr161a

1 of 14

Yes

Drer\gpr161b

1 of 14

Yes

Drer\gpr173

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\LOC100007535

1 of 14

Drer\LOC100330650

1 of 14

Drer\LOC100331077

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\LOC101886918

1 of 14

Yes

Drer\LOC108179103

1 of 14

Drer\LOC108179223

1 of 14

Drer\LOC110438872

1 of 14

Yes

Drer\LOC110438874

1 of 14

Drer\lpar1

1 of 14

Yes

Drer\lpar3

1 of 14

Yes

Drer\lpar4

1 of 14

Yes

Drer\lpar6a

1 of 14

Yes

Drer\mc4r

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\prokr1a

1 of 14

Yes

Drer\qrfprb

1 of 14

Yes

Drer\rrh

1 of 14

Drer\si:ch211-213o11.11

1 of 14

Yes

Drer\si:dkey-96n2.3

1 of 14

Yes

Drer\si:dkey-181m19.17

1 of 14

Drer\si:zfos-169g10.2

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\tmtopsb

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (77)

Cele\ser-5

2 of 14

Yes

Cele\ador-1

1 of 14

Cele\C01F1.4

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Cele\srx-2

1 of 14

Yes

Cele\srx-5

1 of 14

Yes

Cele\srx-8

1 of 14

Yes

Cele\srx-10

1 of 14

Yes

Cele\srx-47

1 of 14

Yes

Cele\srx-62

1 of 14

Yes

Cele\srx-66

1 of 14

Yes

Cele\srx-68

1 of 14

Yes

Cele\tag-89

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (66)

Agam\GPRNNA2

4 of 12

Yes

3 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (0)

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Octβ1R. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (56)

8 of 13

6 of 13

4 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Lkr

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Rh2

1 of 13

Rh3

1 of 13

Rh4

1 of 13

Rh5

1 of 13

Rh6

1 of 13

Rh7

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 1 )

Human Ortholog

Disease

Evidence

References

ADRB3; adrenoceptor beta 3

model of obesity

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

HTR4; 5-hydroxytryptamine receptor 4

7 of 14

602164

ADRB1; adrenoceptor beta 1

5 of 14

109630

ADRB2; adrenoceptor beta 2

4 of 14

109690

ADRB3; adrenoceptor beta 3

4 of 14

109691

OBESITY

obesity

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Octβ1R

suppressible

Octβ2R

(Koon and Budnik, 2012)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Octβ2R

suppressible

Octβ1R

(Lim et al., 2014, Koon and Budnik, 2012)

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0038980

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-75

Cytogenetic map

94B1-94B2

Sequence location

3R:22,497,215..22,520,078 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

94B1-94B2

Limits computationally determined from genome sequence between P{PZ}l(3)rQ178^rQ178 and P{lacW}Dph5^L4910

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-75

(FlyBase, 2016)

3-77.6

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (80)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Korea

12499

P{VT045783-GAL4}attP2

12500

P{VT045789-GAL4}attP2

12770

P{VT045791-GAL4}attP2

13539

P{VT045793-GAL4}attP2

15367

P{VT045788-GAL4}attP2

17457

P{VT045791-lexA}attP2

16109

P{R21E03-nlslexA::p65}attP2

15829

P{VT045783-lexA::GADfl}attP40

17642

P{VT045789-lexA::GADfl}attP40

VDRC

v110537

P{KK102153}VIE-260B

v47895

w¹¹¹⁸ P{GD701}v47895

v47896

w¹¹¹⁸; P{GD701}v47896

More stocks available...

Genomic Clones (33)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (19)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

RH07250

Other clones

IP09384

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0038980

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0038980

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Relationship to Other Genes

Source for database merge of

Source for merge of: oa2 anon-WO0170980.67 anon-WO0170980.68

(FlyBase, 1996-)

Additional comments

Source for merge of oa2 anon-WO0170980.67 anon-WO0170980.68 was sequence comparison ( date:051113 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Source for identity of: oa2 CG6919

(Balfanz et al., 2005)

Source for identity of: Octβ1R oa2

(FlyBase, 2009-)

Nomenclature comments

Changed from 'oa2' to 'Octβ1R' to be consistent with systematic nomenclature of Octβ receptors proposed in FBrf0187885 and FBrf0190865 (and already used for 'Octβ2R' and 'Octβ3R') and to reflect popular usage in the literature.

(FlyBase, 2009-)

Etymology

Synonyms and Secondary IDs (18)

Reported As

Symbol Synonym

CG6919

(Mao et al., 2024, Jayakumar et al., 2016, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Ni et al., 2008, Hauser et al., 2006, Balfanz et al., 2005, Evans and Maqueira, 2005, Maqueira et al., 2005, Metpally and Sowdhamini, 2005, Bryson-Richardson et al., 2004, Elphick and Egertova, 2001, McPartland et al., 2001, Brody and Cravchik, 2000)

DmCG6919

(Roeder et al., 2003)

DmOctΒ1R

(Maqueira et al., 2005)

DmOctβ1R

(Qi et al., 2017, Havekes et al., 2014)

Dmoa2

(Balfanz et al., 2005)

OA2

(Li et al., 2015, Faisal et al., 2014, Kula-Eversole et al., 2010)

Oa2

(Deng, 2020.1.10, Deng et al., 2019, Rao and Deng, 2019.10.23, Kula-Eversole et al., 2010)

OctBeta1

(Evans, 2005.2.16, Evans, 2005.2.16)

Octbeta1R

(Corthals et al., 2023, Schlichting et al., 2022, Rao and Deng, 2019.10.23, Gene Disruption Project members, 2016-, Gene Disruption Project members, 2015-)

anon-WO0170980.67

anon-WO0170980.68

oa2

(Mao et al., 2024, Sun et al., 2023, Branch et al., 2017, Crocker et al., 2016, Sarov et al., 2016, Ashwal-Fluss et al., 2014, Japanese National Institute of Genetics, 2012.5.21, Jungreis, 2011.11.18, Pospisilik et al., 2010)

octβ1R

(Li et al., 2017, Li et al., 2015)

octβ1r

(Sabandal et al., 2020)

Name Synonyms

Octopamine β1 receptor

(Shafer, 2025)

octopamine receptor

(Selcho and Pauls, 2019)

octopamine receptor 2

(Piccirillo et al., 2014, Pfeiffer et al., 2008, Balfanz et al., 2005)

Secondary FlyBase IDs

FBgn0046516
FBgn0046517

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 53 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

42652

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VCZ3

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q9VCZ3

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

E1JIT6

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VCZ3

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0038980

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

42652/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0038980

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0038980

FlyMine - An integrated database for Drosophila genomics

FBgn0038980

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG6919

MARRVEL_MODEL - MARRVEL (model organism gene)

42652

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0038980

DroID - A comprehensive database of gene and protein interactions.

FBgn0038980

DRSC - Results frm RNAi screens

FBgn0038980

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Octbeta1R_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0038980

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0038980

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG6919

Flygut - An atlas of the Drosophila adult midgut

FBgn0038980

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0038980

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC012600

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

References (117)

The following external sites may use different assemblies or annotations than FlyBase.

-0.74

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