FlyBase Allele Report: Dmel\hid[UAS.cUa]

Inducing cell death in somatic clones of terminal tracheal cells by expressing hid^UAS.cUa under the control of Scer\GAL4^btl.PU results in blebbing of the cytoplasm, loss of gass-filling and branch loss in third instar larvae.

(Burguete et al., 2019)

Expression of hid^UAS.cUa under the control of Scer\GAL4^GMR.PF results in a small eye phenotype.

(Yanku et al., 2018)

Expression of hid^UAS.cUa under the control of Scer\GAL4^elav.PU in the embryonic ventral nerve cord significantly increases the volume of apoptotic particles and significantly decreases the numbers of EVE, DAC and CUT expressing neurons, compared to controls.

(Shklover et al., 2015)

Adults expressing W^Scer\UAS.cUa under the control of Scer\GAL4^Tdc2.PC in which all OA neurons are eliminated show axonal projection defects in Gr32a-expressing neurons in the brain, including a severe reduction and disorganisation of Gr32a-expressing leg and labellum termini.

(Andrews et al., 2014)

The NimC4 and drpr-positive glial cells in embryos expressing hid^Scer\UAS.cUa in neurons under the control of Scer\GAL4^elav.PU are abnormal in shape compared to controls as a result of increased glial engulfment of apoptotic particles. No significant difference in glial cell number is observed.

(Shklyar et al., 2014)

In contrast to wild-type D. melanogaster control males, D. melanogaster males expressing W^Scer\UAS.cUa under the control of either Scer\GAL4^Gr32a.3.776 or Scer\GAL4^Gr33a.3.315 show courtship towards D. virilis females. Despite rejection by the D. virilis females, the extent and quality of courtship displayed by these males resembles that seen with conspecific D. melanogaster females. D. melanogaster males expressing W^Scer\UAS.cUa under the control of either Scer\GAL4^Gr32a.3.776 or Scer\GAL4^Gr33a.3.315 also avidly court D. simulans and D. yakuba females.

D. melanogaster males expressing W^Scer\UAS.cUa under the control of either Scer\GAL4^Gr22c.PD, Scer\GAL4^Gr28b.d.PT, Scer\GAL4^{Gr28b.e.4.245}, Scer\GAL4^Gr39a.a.3.4, Scer\GAL4^Gr39a.d.1.7 or Scer\GAL4^Gr64f.9.7 do not show courtship towards D. virilis females.

(Fan et al., 2013)

Under thermophase/cryophase (TC) conditions (flies entrained initially under 12 hour light/12 hour dark conditions for 4 days at 18[o]C, followed by 7 days of thermophase (18 hours at 29[o]C) and cryophase (6 hours at 18[o]C) cycles in constant darkness), flies expressing W^Scer\UAS.cUa under the control of Scer\GAL4^cry.PU show two broad peaks of activity. When these animals are subsequently allowed to free run at 18[o]C in the dark, 41% show rhythmic locomotor activity.

(Lee and Montell, 2013)

Overexpression of W^Scer\UAS.cUa in the developing wing (under the control of Scer\GAL4^vg.PU), results in most flies emerging with ablated wings.

(Morishita et al., 2013)

When W^Scer\UAS.cUa is expressed under the control of Scer\GAL4^GMR.PF at 18[o]C only 69% of pupae eclose. Eye size is reduced compared to controls.

(Pechkovsky et al., 2013)

Expression of W^Scer\UAS.cUa in larval wing disc cells, under the control of Scer\GAL4^ptc-559.1 leads to extensive apoptotic cell death but does not result in invasive cell migration.

(Rudrapatna et al., 2013)

The lymph glands of larvae expressing W^Scer\UAS.cUa under the control of Scer\GAL4^Hml.Δ stain with acridine orange, indicating cell death. TUNEL labelling indicates that the cell death is due to apoptosis.

(Broderick et al., 2012)

Expression of W^Scer\UAS.cUa in all circadian clock neurons (Scer\GAL4^tim.PE) has no effect on light avoidance.

(Keene et al., 2011)

Expression of W^Scer\UAS.cUa under the control Scer\GAL4^c42 results in lethality during embryonic and first instar larval stages.

(Shukla and Tapadia, 2011)

Expression of W^Scer\UAS.cUa under the control of Scer\GAL4^GMR.PF results in eye degeneration.

(Kanao et al., 2010)

Expression of W^Scer\UAS.cUa under the control of Scer\GAL4^Hml.Δ affects the level of plasmatocytes in third instar larvae, with these larvae possessing less than 2% of non-apoptotic plasmatocytes. A significant percentage of these larvae reach pharate adult stage and emerge as phenotypically normal adults. Such adults contain very few remaining plasmatocytes compared to controls. These mutants reach the pupal stage in the same time as wild-type controls and do not contain melanotic tunours or any other obvious phenotypes.

Scer\GAL4^Hml.Δ, W^Scer\UAS.cUa flies show a clear increased susceptibility to infection by both Gram-positive and Gram-negative bacteria. Approximately 67% of plasmatocyte-depleted Scer\GAL4^Hml.Δ, W^Scer\UAS.cUa flies succumb to infection by Enterococcus faecalis within 68 hours of infection. This lethality is correlated with a faster and higher bacterial growth in plasmatocyte depleted Scer\GAL4^Hml.Δ, W^Scer\UAS.cUa flies compared to wild-type. Similar susceptibility is observed when the flies are infected with fungi.

Approximately 55% of Scer\GAL4^Hml.Δ, W^Scer\UAS.cUa larvae die during post-embryonic development, more specifically, at the pupal stage. This pupal partial lethality is completely suppressed by antibiotic treatment.

(Charroux and Royet, 2009)

Expression of W^Scer\UAS.cUa under the control of Scer\GAL4^GMR.PU results in adults with small, rough eyes.

(Protzer et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, enhanceable by Scer\GAL4^byn-Gal4/Ttc30^GD11551

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, enhanceable by Scer\GAL4^byn-Gal4/Twdlα^HMC05749

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, enhanceable by CG15236^KK106695, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, enhanceable by CG15236^JF03064, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, enhanceable by firl^KK112836/Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, enhanceable by CG31139^KK105064, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, enhanceable by Prp38^GD10048, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, enhanceable by CG7296^HMS05715, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, enhanceable by CG17187^HMC03923, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, enhanceable by Prp38^KK100458, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, enhanceable by CG17187^GD9309, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, enhanceable by Scer\GAL4^byn-Gal4/pie^HMJ30102

(Sawyer et al., 2025)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has increased size | adult stage phenotype, enhanceable by LIMK1^UAS.Tag:HA, Scer\GAL4^ey.PU

(Farrell et al., 2022)

Scer\GAL4^Or42b.PF, hid^UAS.cUa, rpr^UAS.cUa has abnormal behavior | adult stage phenotype, enhanceable by Scer\GAL4^Ir68a.PK, hid^UAS.cUa, rpr^UAS.cUa

(Li et al., 2022)

Scer\GAL4^Ir68a.PK, hid^UAS.cUa, rpr^UAS.cUa has abnormal behavior | adult stage phenotype, enhanceable by Scer\GAL4^Or42b.PF, hid^UAS.cUa, rpr^UAS.cUa

(Li et al., 2022)

Scer\GAL4^elav.PU, hid^UAS.cUa has increased cell death | embryonic stage phenotype, enhanceable by NimC4^KO/NimC4^KO

(Shklover et al., 2015)

hid¹¹⁰, hid^UAS.cUa has abnormal phototaxis phenotype, enhanceable by rpr^UAS.cUa/Scer\GAL4^ppk.1.9

(Xiang et al., 2010)

NOT Enhanced by

Statement

Reference

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, non-enhanceable by CG42554^GD8152, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, non-enhanceable by CG10211^HMJ30098, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, non-enhanceable by CG33307^GD16054, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, non-enhanceable by Efr^GD3254, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, non-enhanceable by CG31810^GD17434, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, non-enhanceable by Rh7^HMC05183, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, non-enhanceable by CG10211^GD5320, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, non-enhanceable by GCC88^GD12600, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, non-enhanceable by CG9928^GD405, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, non-enhanceable by Scer\GAL4^byn-Gal4/Uhg5^HMJ21153

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, non-enhanceable by Pp1-87B^GD11720, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, non-enhanceable by CG5245^HMJ21479, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased cell death | adult stage phenotype, non-enhanceable by Tep5Ψ^HMJ23163/Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^elav.PU, hid^UAS.cUa has decreased cell number | embryonic stage phenotype, non-enhanceable by NimC4^KO/NimC4^KO

(Shklover et al., 2015)

Scer\GAL4^GMR.PU, hid^UAS.cUa has visible phenotype, non-enhanceable by α4GT1^EP797, Scer\GAL4^GMR.PU

(Protzer et al., 2009)

Scer\GAL4^GMR.PU, hid^UAS.cUa has visible phenotype, non-enhanceable by α4GT1^RNAi.UASp, Scer\GAL4^GMR.PU

(Protzer et al., 2009)

Suppressed by

Statement

Reference

Scer\GAL4^GMR9D11, hid^UAS.cUa, rpr^UAS.cUa has decreased cell number | larval stage phenotype, suppressible | partially by Delta^UAS.cUa

(Zhang et al., 2024)

Scer\GAL4^GMR9D11, hid^UAS.cUa, rpr^UAS.cUa has decreased cell number | larval stage phenotype, suppressible | partially by BacA\p35^UAS.cHa

(Zhang et al., 2024)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has increased size | adult stage phenotype, suppressible | partially by LIMK1^HMJ02235, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has visible | adult stage phenotype, suppressible | partially by LIMK1^HMJ02235, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has increased size | adult stage phenotype, suppressible | partially by LIMK1^HMS04455, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has increased size | adult stage phenotype, suppressible | partially by LIMK1^JF02063, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has visible | adult stage phenotype, suppressible | partially by LIMK1^JF02063, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has visible | adult stage phenotype, suppressible | partially by LIMK1^HMS04455, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has increased size | adult stage phenotype, suppressible | partially by LIMK1²

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has visible | adult stage phenotype, suppressible | partially by LIMK1²

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has visible | adult stage phenotype, suppressible | partially by tsr^UAS.cNa, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has increased occurrence of cell division | larval stage phenotype, suppressible by LIMK1^HMS04455, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has increased occurrence of cell division | larval stage phenotype, suppressible by tsr^UAS.cNa, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has increased occurrence of cell division | larval stage phenotype, suppressible by Dronc^HMS00758, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^nub.PK, hid^UAS.cUa has increased size | larval stage phenotype, suppressible by LIMK1^HMS04455, Scer\GAL4^nub.PK

(Farrell et al., 2022)

BacA\p35^UAS.cUa, LIMK1^UAS.Tag:HA, Scer\GAL4^ey.PU, hid^UAS.cUa has abnormal size | adult stage phenotype, suppressible by Myo31DF^HMS00928, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, LIMK1^UAS.Tag:HA, Scer\GAL4^ey.PU, hid^UAS.cUa has increased size | larval stage phenotype, suppressible by Myo31DF^HMS00928, Scer\GAL4^ey.PU

(Farrell et al., 2022)

Scer\GAL4^eg-Mz360, hid^UAS.cUa has decreased cell number | larval stage phenotype, suppressible | partially by Scer\GAL4^eg-Mz360/hb^UAS.cWa

(Pérez et al., 2022)

Scer\GAL4^elav.PU, hid^UAS.cUa has increased cell death | embryonic stage phenotype, suppressible by egr¹/egr¹

(Shklover et al., 2015)

Scer\GAL4^elav.PU, hid^UAS.cUa has decreased cell number | embryonic stage phenotype, suppressible by egr¹/egr¹

(Shklover et al., 2015)

Scer\GAL4^elav.PU, hid^UAS.cUa has abnormal neuroanatomy | embryonic stage phenotype, suppressible by egr¹/egr¹

(Shklover et al., 2015)

Scer\GAL4^vg.PU, hid^UAS.cUa has increased cell death phenotype, suppressible by Cdk7^S164A.T170A

(Morishita et al., 2013)

Scer\GAL4^GMR.PF, hid^UAS.cUa has partially lethal - majority live phenotype, suppressible by HAdV-C\E4orf4^UAS.cPa, Scer\GAL4^GMR.PF

(Pechkovsky et al., 2013)

Scer\GAL4^GMR.PF, hid^UAS.cUa has some die during pupal stage phenotype, suppressible by HAdV-C\E4orf4^UAS.cPa, Scer\GAL4^GMR.PF

(Pechkovsky et al., 2013)

Scer\GAL4^GMR.PF, hid^UAS.cUa has visible | adult stage phenotype, suppressible by HAdV-C\E4orf4^UAS.cPa, Scer\GAL4^GMR.PF

(Pechkovsky et al., 2013)

Scer\GAL4^GMR.PF, hid^UAS.cUa has abnormal size | adult stage phenotype, suppressible by HAdV-C\E4orf4^UAS.cPa, Scer\GAL4^GMR.PF

(Pechkovsky et al., 2013)

BacA\p35^UAS.cHa, Scer\GAL4^ptc-559.1, hid^UAS.cUa has abnormal cell migration phenotype, suppressible by msn⁰⁶⁹⁴⁶, Scer\GAL4^ptc-559.1

(Rudrapatna et al., 2013)

BacA\p35^UAS.cHa, Scer\GAL4^ptc-559.1, hid^UAS.cUa has abnormal cell migration phenotype, suppressible by bsk^K53R.UAS, Scer\GAL4^ptc-559.1

(Rudrapatna et al., 2013)

BacA\p35^UAS.cHa, Scer\GAL4^ptc-559.1, hid^UAS.cUa has abnormal cell migration phenotype, suppressible by Dronc^NIG.8091R, Scer\GAL4^ptc-559.1

(Rudrapatna et al., 2013)

BacA\p35^UAS.cHa, Scer\GAL4^ptc-559.1, hid^UAS.cUa has abnormal cell migration phenotype, suppressible by Drice^NIG.7788R, Scer\GAL4^ptc-559.1

(Rudrapatna et al., 2013)

Scer\GAL4^ppk.PG, hid^UAS.cUa, rpr^UAS.cUa has increased cell death | third instar larval stage phenotype, suppressible by BacA\p35^UAS.cUa, Scer\GAL4^ppk.PG

(Bhattacharya et al., 2012)

Scer\GAL4^Hml.Δ, hid^UAS.cUa has increased cell death | larval stage phenotype, suppressible by BacA\p35^UAS.cUa, Scer\GAL4^Hml.Δ

(Broderick et al., 2012)

Scer\GAL4^Hml.Δ, hid^UAS.cUa has increased cell death phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^Hml.Δ

(Charroux and Royet, 2009)

Scer\GAL4^Hml.Δ, hid^UAS.cUa has partially lethal - majority die | pupal stage phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^Hml.Δ

(Charroux and Royet, 2009)

NOT suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, hid^UAS.cUa has abnormal size | adult stage phenotype, non-suppressible by HUWE1^EY01689, Scer\GAL4^GMR.PF

(Yanku et al., 2018)

Scer\GAL4^GMR.PF, hid^UAS.cUa has visible | adult stage phenotype, non-suppressible by HUWE1^EY01689, Scer\GAL4^GMR.PF

(Yanku et al., 2018)

Scer\GAL4^elav.PU, hid^UAS.cUa has decreased cell number | embryonic stage phenotype, non-suppressible by NimC4^KO/NimC4^KO

(Shklover et al., 2015)

Scer\GAL4^GMR.PU, hid^UAS.cUa has visible phenotype, non-suppressible by α4GT1^EP797, Scer\GAL4^GMR.PU

(Protzer et al., 2009)

Scer\GAL4^GMR.PU, hid^UAS.cUa has visible phenotype, non-suppressible by α4GT1^RNAi.UASp, Scer\GAL4^GMR.PU

(Protzer et al., 2009)

Enhancer of

Statement

Reference

Scer\GAL4^Or42b.PF, hid^UAS.cUa, rpr^UAS.cUa is an enhancer of abnormal behavior | adult stage phenotype of Scer\GAL4^Ir68a.PK, hid^UAS.cUa, rpr^UAS.cUa

(Li et al., 2022)

Scer\GAL4^Ir68a.PK, hid^UAS.cUa, rpr^UAS.cUa is an enhancer of abnormal behavior | adult stage phenotype of Scer\GAL4^Or42b.PF, hid^UAS.cUa, rpr^UAS.cUa

(Li et al., 2022)

Other

Statement

Reference

Scer\GAL4^NP0001, hid^UAS.cUa, rpr^UAS.cUa has abnormal size | adult stage phenotype

(Sawyer et al., 2025)

Scer\GAL4^esg.PU, hid^UAS.cUa, rpr^UAS.cUa has abnormal cell number | adult stage phenotype

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa, loofah^KK105655 has increased cell death | adult stage phenotype

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa, loofah^KK105655 has decreased cell number | adult stage phenotype

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa, loofah^KK105655 has increased mortality phenotype

(Sawyer et al., 2025)

Diap1^RNAi.UAS.cUa, Scer\GAL4^byn-Gal4, hid^UAS.cUa has increased mortality phenotype

(Sawyer et al., 2025)

LIMK1^HMS04455, Scer\GAL4^mirr-DE, hid^UAS.cUa has abnormal size | adult stage phenotype

(Farrell et al., 2022)

Scer\GAL4^mirr-DE, hid^UAS.cUa, tsr^UAS.cNa has abnormal size | adult stage phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has visible | adult stage phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has increased occurrence of cell division | larval stage phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has increased size | adult stage phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^nub.PK, hid^UAS.cUa has increased size | larval stage phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, LIMK1^UAS.Tag:HA, Scer\GAL4^ey.PU, hid^UAS.cUa has abnormal size | adult stage phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, LIMK1^UAS.Tag:HA, Scer\GAL4^ey.PU, hid^UAS.cUa has partially lethal phenotype

(Farrell et al., 2022)

Scer\GAL4^Tk.PS, hid^UAS.cUa, rpr^UAS.cUa has decreased cell number | oogenesis | conditional phenotype

(Ameku et al., 2018)

Scer\GAL4^{5-HT2A-PL00052}, hid^UAS.cUa, rpr^UAS.cUa has abnormal memory | larval stage | conditional phenotype

(Huser et al., 2017)

Scer\GAL4^Trhn.PB, hid^UAS.cUa, rpr^UAS.cUa has abnormal memory | larval stage phenotype

(Huser et al., 2017)

Scer\GAL4^GMR58E02, hid^UAS.cUa, rpr^UAS.cUa has abnormal memory | adult stage | nutrition conditional phenotype

(Rohwedder et al., 2016)

Scer\GAL4^GMR64H06, hid^UAS.cUa, rpr^UAS.cUa has abnormal memory | adult stage | nutrition conditional phenotype

(Rohwedder et al., 2016)

Scer\GAL4^GMR57B04, hid^UAS.cUa, rpr^UAS.C has abnormal chemosensory behavior | larval stage phenotype

(van Giesen et al., 2016)

Scer\GAL4^GMR57B04, hid^UAS.cUa, rpr^UAS.C has abnormal locomotor behavior | larval stage | chemical conditional phenotype

(van Giesen et al., 2016)

Scer\GAL4^EL.eveRC, hid^UAS.cUa, rpr^UAS.cUa has uncoordinated | larval stage phenotype

(Heckscher et al., 2015)

Scer\GAL4^EL.eveRC, hid^UAS.cUa, rpr^UAS.cUa has abnormal locomotor behavior | larval stage phenotype

(Heckscher et al., 2015)

Scer\GAL4^NPF.1, hid^UAS.cUa, rpr^UAS.C has abnormal feeding behavior | larval stage | nutrition conditional phenotype

(Rohwedder et al., 2015)

Scer\GAL4^NPF.1, hid^UAS.cUa, rpr^UAS.C has abnormal memory | larval stage | nutrition conditional phenotype

(Rohwedder et al., 2015)

Scer\GAL4^Tdc2.PC, Scer\GAL80^{tsh-md621-GAL80}, hid^UAS.cUa, rpr^UAS.cUa has abnormal learning | nutrition conditional phenotype

(Selcho et al., 2014)

Scer\GAL4^Ilp7.PC, hid^UAS.cUa, rpr^UAS.C has decreased fecundity | female phenotype

(Castellanos et al., 2013)

Scer\GAL4^cry.PU, TrpA1¹, hid^UAS.cUa has abnormal locomotor rhythm phenotype

(Lee and Montell, 2013)

BacA\p35^UAS.cHa, Scer\GAL4^ptc-559.1, hid^UAS.cUa has abnormal cell migration phenotype

(Rudrapatna et al., 2013)

Scer\GAL4^ppk.PG, hid^UAS.cUa, rpr^UAS.cUa has increased cell death | third instar larval stage phenotype

(Bhattacharya et al., 2012)

Scer\GAL4^Trhn.PB, hid^UAS.cUa, rpr^UAS.cUa has abnormal locomotor behavior | larval stage | nutrition conditional phenotype

(Huser et al., 2012)

Scer\GAL4^Trhn.PB, hid^UAS.cUa, rpr^UAS.cUa has abnormal chemosensory behavior | larval stage | nutrition conditional phenotype

(Huser et al., 2012)

Scer\GAL4^Tdc2.PC, hid^UAS.cUa, rpr^UAS.cUa has abnormal locomotor behavior | larval stage phenotype

(Selcho et al., 2012)

Scer\GAL4^Rh5.PT, hid^UAS.cUa, rpr^UAS.C has abnormal phototaxis | larval stage phenotype

(Keene et al., 2011)

Scer\GAL4^tim.PE, hid^UAS.cUa, rpr^UAS.C has abnormal phototaxis | larval stage phenotype

(Keene et al., 2011)

Scer\GAL4^ppk.1.9, hid^UAS.cUa, rpr^UAS.cUa has abnormal phototaxis phenotype

(Xiang et al., 2010)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult anterior hindgut phenotype, enhanceable by Scer\GAL4^byn-Gal4/Ttc30^GD11551

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult anterior hindgut phenotype, enhanceable by Scer\GAL4^byn-Gal4/Twdlα^HMC05749

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult anterior hindgut phenotype, enhanceable by CG15236^KK106695, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult anterior hindgut phenotype, enhanceable by CG15236^JF03064, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult pylorus phenotype, enhanceable by firl^KK112836/Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult pylorus phenotype, enhanceable by CG31139^KK105064, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult pylorus phenotype, enhanceable by Prp38^GD10048, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult pylorus phenotype, enhanceable by CG7296^HMS05715, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult pylorus phenotype, enhanceable by CG17187^HMC03923, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult pylorus phenotype, enhanceable by Prp38^KK100458, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult pylorus phenotype, enhanceable by CG17187^GD9309, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult pylorus phenotype, enhanceable by Scer\GAL4^byn-Gal4/pie^HMJ30102

(Sawyer et al., 2025)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has eye disc | larval stage phenotype, enhanceable by LIMK1^UAS.Tag:HA, Scer\GAL4^ey.PU

(Farrell et al., 2022)

Scer\GAL4^elav.PU, hid^UAS.cUa has larval ventral nerve cord | embryonic stage phenotype, enhanceable by NimC4^KO/NimC4^KO

(Shklover et al., 2015)

NOT Enhanced by

Statement

Reference

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult gut phenotype, non-enhanceable by CG42554^GD8152, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult gut phenotype, non-enhanceable by CG10211^HMJ30098, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult gut phenotype, non-enhanceable by CG33307^GD16054, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult gut phenotype, non-enhanceable by Efr^GD3254, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult gut phenotype, non-enhanceable by CG31810^GD17434, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult gut phenotype, non-enhanceable by Rh7^HMC05183, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult gut phenotype, non-enhanceable by CG10211^GD5320, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult gut phenotype, non-enhanceable by GCC88^GD12600, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult gut phenotype, non-enhanceable by CG9928^GD405, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult gut phenotype, non-enhanceable by Scer\GAL4^byn-Gal4/Uhg5^HMJ21153

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult gut phenotype, non-enhanceable by Pp1-87B^GD11720, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult gut phenotype, non-enhanceable by CG5245^HMJ21479, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult gut phenotype, non-enhanceable by Tep5Ψ^HMJ23163/Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^elav.PU, hid^UAS.cUa has neuron | embryonic stage phenotype, non-enhanceable by NimC4^KO/NimC4^KO

(Shklover et al., 2015)

Scer\GAL4^GMR.PU, hid^UAS.cUa has eye phenotype, non-enhanceable by α4GT1^EP797, Scer\GAL4^GMR.PU

(Protzer et al., 2009)

Scer\GAL4^GMR.PU, hid^UAS.cUa has eye phenotype, non-enhanceable by α4GT1^RNAi.UASp, Scer\GAL4^GMR.PU

(Protzer et al., 2009)

Suppressed by

Statement

Reference

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult pylorus phenotype, suppressible by BacA\p35^UAS.cUa, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa has adult pylorus phenotype, suppressible by Diap1^UAS.cUa, Scer\GAL4^byn-Gal4

(Sawyer et al., 2025)

Scer\GAL4^GMR9D11, hid^UAS.cUa, rpr^UAS.cUa has type II neuroblast | larval stage | decreased number phenotype, suppressible | partially by Delta^UAS.cUa

(Zhang et al., 2024)

Scer\GAL4^GMR9D11, hid^UAS.cUa, rpr^UAS.cUa has type II neuroblast | larval stage | decreased number phenotype, suppressible | partially by BacA\p35^UAS.cHa

(Zhang et al., 2024)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has adult head phenotype, suppressible | partially by LIMK1^HMJ02235, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has adult head phenotype, suppressible | partially by LIMK1^HMS04455, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has adult head phenotype, suppressible | partially by LIMK1^JF02063, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has adult head phenotype, suppressible | partially by LIMK1²

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has adult head phenotype, suppressible | partially by tsr^UAS.cNa, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has eye disc | larval stage phenotype, suppressible by LIMK1^HMS04455, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has eye disc | larval stage phenotype, suppressible by tsr^UAS.cNa, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has filamentous actin | larval stage phenotype, suppressible by LIMK1²

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has filamentous actin | larval stage phenotype, suppressible by Dronc^HMS00758, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has eye disc | larval stage phenotype, suppressible by Dronc^HMS00758, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has filamentous actin | larval stage phenotype, suppressible by tsr^UAS.cNa, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has eye disc | larval stage phenotype, suppressible by LIMK1²

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^nub.PK, hid^UAS.cUa has wing pouch | larval stage phenotype, suppressible by LIMK1^HMS04455, Scer\GAL4^nub.PK

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^nub.PK, hid^UAS.cUa has filamentous actin | larval stage phenotype, suppressible by LIMK1^HMS04455, Scer\GAL4^nub.PK

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa has eye disc | somatic clone | larval stage phenotype, suppressible by Dronc^HMS00758, Scer\GAL4^Act.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa has filamentous actin | somatic clone | larval stage phenotype, suppressible by Dronc^HMS00758, Scer\GAL4^Act.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa has eye disc | somatic clone | larval stage phenotype, suppressible by LIMK1^HMS04455, Scer\GAL4^Act.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa has filamentous actin | somatic clone | larval stage phenotype, suppressible by LIMK1^HMS04455, Scer\GAL4^Act.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa has eye disc | somatic clone | larval stage phenotype, suppressible by LIMK1²

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa has filamentous actin | somatic clone | larval stage phenotype, suppressible by LIMK1²

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa has eye disc | somatic clone | larval stage phenotype, suppressible by tsr^UAS.cNa, Scer\GAL4^Act.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa has filamentous actin | somatic clone | larval stage phenotype, suppressible by tsr^UAS.cNa, Scer\GAL4^Act.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa has filamentous actin | somatic clone | larval stage phenotype, suppressible by Myo31DF^HMS00928, Scer\GAL4^Act.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa has eye disc | somatic clone | larval stage phenotype, suppressible by Myo31DF^HMS00928, Scer\GAL4^Act.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, LIMK1^UAS.Tag:HA, Scer\GAL4^ey.PU, hid^UAS.cUa has adult head phenotype, suppressible by Myo31DF^HMS00928, Scer\GAL4^ey.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, LIMK1^UAS.Tag:HA, Scer\GAL4^ey.PU, hid^UAS.cUa has eye disc | larval stage phenotype, suppressible by Myo31DF^HMS00928, Scer\GAL4^ey.PU

(Farrell et al., 2022)

Scer\GAL4^eg-Mz360, hid^UAS.cUa has larval ventral nerve cord phenotype, suppressible | partially by Scer\GAL4^eg-Mz360/hb^UAS.cWa

(Pérez et al., 2022)

Scer\GAL4^elav.PU, hid^UAS.cUa has neuron | embryonic stage phenotype, suppressible by egr¹/egr¹

(Shklover et al., 2015)

Scer\GAL4^elav.PU, hid^UAS.cUa has larval ventral nerve cord | embryonic stage phenotype, suppressible by egr¹/egr¹

(Shklover et al., 2015)

Scer\GAL4^GMR.PU, hid^UAS.cUa has eye phenotype, suppressible by SRm160[+]/Srrm1^B103

(Fan et al., 2014)

Scer\GAL4^vg.PU, hid^UAS.cUa has wing phenotype, suppressible by Cdk7^S164A.T170A

(Morishita et al., 2013)

Scer\GAL4^GMR.PF, hid^UAS.cUa has eye phenotype, suppressible by HAdV-C\E4orf4^UAS.cPa, Scer\GAL4^GMR.PF

(Pechkovsky et al., 2013)

Scer\GAL4^ppk.PG, hid^UAS.cUa, rpr^UAS.cUa has abdominal sensory neuron | third instar larval stage phenotype, suppressible by BacA\p35^UAS.cUa, Scer\GAL4^ppk.PG

(Bhattacharya et al., 2012)

Scer\GAL4^Hml.Δ, hid^UAS.cUa has embryonic/larval lymph gland | larval stage phenotype, suppressible by BacA\p35^UAS.cUa, Scer\GAL4^Hml.Δ

(Broderick et al., 2012)

Scer\GAL4^Hml.Δ, hid^UAS.cUa has embryonic/larval plasmatocyte phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^Hml.Δ

(Charroux and Royet, 2009)

NOT suppressed by

Statement

Reference

BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa has filamentous actin | somatic clone | larval stage phenotype, non-suppressible by bsk^DN.UAS, Scer\GAL4^Act.PU

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa has eye disc | somatic clone | larval stage phenotype, non-suppressible by Tak1²⁵²⁷

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa has filamentous actin | somatic clone | larval stage phenotype, non-suppressible by Tak1²⁵²⁷

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa has eye disc | somatic clone | larval stage phenotype, non-suppressible by bsk^DN.UAS, Scer\GAL4^Act.PU

(Farrell et al., 2022)

Scer\GAL4^GMR.PF, hid^UAS.cUa has eye phenotype, non-suppressible by HUWE1^EY01689, Scer\GAL4^GMR.PF

(Yanku et al., 2018)

Scer\GAL4^elav.PU, hid^UAS.cUa has neuron | embryonic stage phenotype, non-suppressible by NimC4^KO/NimC4^KO

(Shklover et al., 2015)

Scer\GAL4^GMR.PU, hid^UAS.cUa has eye phenotype, non-suppressible by α4GT1^EP797, Scer\GAL4^GMR.PU

(Protzer et al., 2009)

Scer\GAL4^GMR.PU, hid^UAS.cUa has eye phenotype, non-suppressible by α4GT1^RNAi.UASp, Scer\GAL4^GMR.PU

(Protzer et al., 2009)

Other

Statement

Reference

Scer\GAL4^NP0001, hid^UAS.cUa, rpr^UAS.cUa has nucleus | adult stage phenotype

(Sawyer et al., 2025)

Scer\GAL4^NP0001, hid^UAS.cUa, rpr^UAS.cUa has adult midgut enterocyte phenotype

(Sawyer et al., 2025)

Scer\GAL4^esg.PU, hid^UAS.cUa, rpr^UAS.cUa has adult midgut phenotype

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa, loofah^KK105655 has adult anterior hindgut phenotype

(Sawyer et al., 2025)

Scer\GAL4^byn-Gal4, hid^UAS.cUa, loofah^KK105655 has nucleus | adult stage phenotype

(Sawyer et al., 2025)

LIMK1^HMS04455, Scer\GAL4^mirr-DE, hid^UAS.cUa has eye disc | larval stage phenotype

(Farrell et al., 2022)

Scer\GAL4^mirr-DE, hid^UAS.cUa, tsr^UAS.cNa has eye disc | larval stage phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has adult head phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has eye disc | larval stage phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has filamentous actin | larval stage phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has ocellus | increased number | adult stage phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^ey.PU, hid^UAS.cUa has adult head bristle | increased number | adult stage phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^nub.PK, hid^UAS.cUa has filamentous actin | larval stage phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^nub.PK, hid^UAS.cUa has wing pouch | larval stage phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, LIMK1^UAS.Tag:HA, Scer\GAL4^ey.PU, hid^UAS.cUa has adult head phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, LIMK1^UAS.Tag:HA, Scer\GAL4^ey.PU, hid^UAS.cUa has eye | adult stage | absent phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa has eye disc | somatic clone | larval stage phenotype

(Farrell et al., 2022)

BacA\p35^UAS.cUa, Scer\GAL4^Act.PU, hid^UAS.cUa has filamentous actin | somatic clone | larval stage phenotype

(Farrell et al., 2022)

Scer\GAL4^Tk.PS, hid^UAS.cUa, rpr^UAS.cUa has female germline stem cell | conditional phenotype

(Ameku et al., 2018)

Scer\GAL4^EL.eveRC, hid^UAS.cUa, rpr^UAS.cUa has embryonic/larval hypodermal muscle cell phenotype

(Heckscher et al., 2015)

Scer\GAL4^ppk.PG, hid^UAS.cUa, rpr^UAS.cUa has abdominal sensory neuron | third instar larval stage phenotype

(Bhattacharya et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Females co-expressing rpr^UAS.cUa and hid^UAS.cUa under the control of Scer\GAL4^Tk.PS show the expected mating-induced increase in germline stem cells in the germarium, as compared to controls.

(Ameku et al., 2018)

One copy of SRm160^B103 slightly suppresses the apoptosis seen in the eye when hid^Scer\UAS.cUa is expressed under the control of Scer\GAL4^GMR.PU.

(Fan et al., 2014)

Selective ablation of octopamine/tyramine neurons in the brains through co-expression of hid^Scer\UAS.cUa and rpr^Scer\UAS.cUa under the control of Scer\GAL4^Tdc2.PC and VNC-specific Scer\GAL80^tsh-GAL80 does not lead to any deficit in appetitive olfactory learning when fructose is given as a reward. Larvae also exhibit robust appetitive memory when sorbitol is used as a reward, comparable to that of genetic controls. In contrast, the larvae fail to show significant learning when rewarded with arabinose; memory performance is significantly reduced compared with controls. Perception of the odors (amyl acetate and benzaldehyde) is unaffected, and larvae show normal attraction behavior toward arabinose and perform indistinguishably from controls.

(Selcho et al., 2014)

When embryonic Ilp7 neurons are killed using W^Scer\UAS.cUa and rpr^Scer\UAS.C (post-embryonic Ilp7 neurons are retained by limiting expression to the first and second instar larval stages using Scer\GAL80^ts.αTub84B) female egg laying is normal.

When males express W^Scer\UAS.cUa and rpr^Scer\UAS.C under the control of Scer\GAL4^Ilp7.PC female egg laying is reduced on the first day after eclosion compared to wild type males, but subsequent egg laying is normal.

Females expressing W^Scer\UAS.cUa and rpr^Scer\UAS.C throughout development under the control of Scer\GAL4^Ilp7.PC have severely reduced egg laying. These females also have distended abdomens and eggs are always found jammed in the lateral oviduct. Of the small number of egg laid by these females, only 40% produce viable larvae.

(Castellanos et al., 2013)

Activity peaks during thermophase/cryophase cycles are virtually eliminated in TrpA1¹ flies expressing W^Scer\UAS.cUa under the control of Scer\GAL4^cry.PU. When these flies are subsequently allowed to free run at a constant temperature (either 18[o]C or 29[o]C) in constant darkness, only 6% show rhythmic locomotor activity.

(Lee and Montell, 2013)

The degree of wing ablation observed in flies expressing W^Scer\UAS.cUa under the control of Scer\GAL4^vg.PU is strongly reduced in a Cdk7^S164A.T170A background.

(Morishita et al., 2013)

The co-expression of hid^UAS.cUa and rpr^UAS.cUa under the control of Scer\GAL4^ppk.PG induces some apoptosis in third instar larval sensory neurons, as compared to controls.

(Bhattacharya et al., 2012)

Expression of both W^Scer\UAS.cUa and rpr^Scer\UAS.C under the control of Scer\GAL4^Rh5.PT abolishes light avoidance at the larval stage. However, expression under the control of Scer\GAL4^Rh6.PD does not affect light avoidance.

Expression of both W^Scer\UAS.cUa and rpr^Scer\UAS.C efficiently ablates all circadian clock neurons (Scer\GAL4^tim.PE), leaving larvae with a seriously disrupted light avoidance phenotype. This phenotype is no different in LD or DD conditions.

Expression of both W^Scer\UAS.cUa and rpr^Scer\UAS.C efficiently ablates the lateral neurons (Scer\GAL4^P2.4.Pdf) but has no effect on light avoidance.

(Keene et al., 2011)

hid¹¹⁰ mutants expressing both hid^Scer\UAS.cUa and rpr^Scer\UAS.cUa in class IV dendritic arborization neurons (under the control of Scer\GAL4^ppk.1.9) show markedly decreased white-light-avoidance behavior compared to wild-type and hid¹¹⁰ (bolwig-organ-ablated) mutants.

Expression of both hid^Scer\UAS.cUa and rpr^Scer\UAS.cUa in class IV dendritic arborization neurons (under the control of Scer\GAL4^ppk.1.9) results in marked decrease in white-light-avoidance behavior compared to wild-type.

(Xiang et al., 2010)

Co-expression of either α4GT1^EP797 or α4GT1^{dsRNA.Scer\UAS.P\T} has no effect on the adult eye phenotype caused by expression of W^Scer\UAS.cUa under the control of Scer\GAL4^GMR.PU.

(Protzer et al., 2009)

Xenogenetic Interactions

Statement

Reference

Expression of Zzzz\E4orf4^Scer\UAS.cPa suppresses the semi-viability seen when W^Scer\UAS.cUa is expressed under the control of Scer\GAL4^GMR.PF at 18[o]C. 95% of pupae eclose (compared to 69%). The reduction in eye size is also partially suppressed.

(Pechkovsky et al., 2013)

Larval wing disc cells expressing BacA\p35^Scer\UAS.cHa and W^Scer\UAS.cUa under the control of Scer\GAL4^ptc-559.1 display invading cells exclusively in basal planes of the tissue; these cells have cleanly detached and migrate several cell diameters away from the posterior edge of the ptc domain. They display a robust, rounded morphology indicative of healthy cells.

The BacA\p35^Scer\UAS.cHa-W^Scer\UAS.cUa invasive cell phenotype is completely suppressed in the presence of msn⁰⁶⁹⁴⁶.

The BacA\p35^Scer\UAS.cHa-W^Scer\UAS.cUa invasive cell phenotype is completely suppressed by co-expression of bsk^{K53R.Scer\UAS}.

Knockdown of Nc, through expression of Nc^NIG.8091R completely suppresses the invasive cell phenotype found upon co-expression of BacA\p35^Scer\UAS.cHa-W^Scer\UAS.cUa under the control of Scer\GAL4^ptc-559.1.

Reducing Ice levels, through expression of Ice^NIG.7788R, suppresses the invasive cell phenotype found upon co-expression of BacA\p35^Scer\UAS.cHa-W^Scer\UAS.cUa under the control of Scer\GAL4^ptc-559.1.

(Rudrapatna et al., 2013)

Co-expression of BacA\p35^Scer\UAS.cUa suppresses the cell death seen in the lymph glands of larvae expressing W^Scer\UAS.cUa under the control of Scer\GAL4^Hml.Δ.

(Broderick et al., 2012)

Expression of BacA\p35^Scer\UAS.cHa rescues the pupal partial lethality found upon expression of W^Scer\UAS.cUa under the control of Scer\GAL4^Hml.Δ through blocking plasmatocyte apoptosis.

(Charroux and Royet, 2009)

Complementation and Rescue Data

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Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

W^Scer\UAS.cUa

hid^Scer\UAS.cUa

hid^UAS.cUa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Unknown

Secondary FlyBase IDs

References (107)

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