AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.44
Gene model reviewed during 5.45
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\net using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\net in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Egfr signalling and net exert mutually antagonising activities during the specification of wing vein versus intervein fate. net is required to maintain intervein development by restricting Egfr signalling to the net-free vein regions of the wing disc.
Mutants display hyperplastic phenotype, showing tissue overgrowth in mitotic recombination clones.
Mutations in net cause extra longitudinal or transverse veins with plexated vein phenotypes. Px, px, net, dsr and emc belong to the same synergistic group and act synergistically against kn, fu and shf.
Px, net, dsr, px and emc loci belong to the plexus phenotypic group within the 'excess-of-vein' mutant class. Extra veins occur parallel to and between normal veins that connect to each other by crossveins, forming plexi. Plexi are distal. Proximal regions shift to the margin leaving a central area devoid of veins. Sensilla and chaetae appear shifted. Combinations of mutations produce superadditive phenotypes.