|Citation||White, K.P., Rifkin, S.A., Hurban, P., Hogness, D.S. (1999). Microarray analysis of Drosophila development during metamorphosis. Science 286(5447): 2179--2184. (Export to RIS)|
|Publication Type||Research paper|
|PubMed Abstract||Metamorphosis is an integrated set of developmental processes controlled by a transcriptional hierarchy that coordinates the action of hundreds of genes. In order to identify and analyze the expression of these genes, high-density DNA microarrays containing several thousand Drosophila melanogaster gene sequences were constructed. Many differentially expressed genes can be assigned to developmental pathways known to be active during metamorphosis, whereas others can be assigned to pathways not previously associated with metamorphosis. Additionally, many genes of unknown function were identified that may be involved in the control and execution of metamorphosis. The utility of this genome-based approach is demonstrated for studying a set of complex biological processes in a multicellular organism.|
|Personal communication to FlyBase||EST clones in Science 286:2179-2184 paper.
White, 2000.2.23, EST clones in Science 286:2179-2184 paper. [FBrf0125065]
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|Language of Publication||English|
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