- Tools
- Downloads
- Links
- Community
- About
- Help
FB2026_01
,
released March 12, 2026
Ubc9, DmUbc9, semi, dUbc9, semushi
SUMO E2-conjugating enzyme - stabilizes proteins against ubiquitinization and subsequent degradation - regulates hematopoiesis - holds the Toll pathway in check
Please see the JBrowse view of Dmel\lwr for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.42
Gene model reviewed during 5.46
1.2 (northern blot)
0.736 (longest cDNA)
159 (aa)
159 (aa); 18 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\lwr using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Maternal lwr transcripts are distributed throughout the embryo until stage 10 and then decrease gradually. From stage 14 until the end of embryogenesis, transcripts are observed in the embryonic gonads in the pole cells. Within ovaries, transcripts are weakly detected in the germarium, are strongly expressed in stage S1-10 nurse cells and are weakly detected in the oocyte up until stage S10. lwr transcripts are weakly expressed in spermatogonial cells at the tip region and remain detectable in the spermatocytes and spermatids.
lwr transcripts are provided maternally and are expressed throughout embryogenesis.
lwr transcript accumulates at the anterior end of syncytial blastoderm embryos.
JBrowse - Visual display of RNA-Seq signals
View Dmel\lwr in JBrowse2-1.5
2-0.2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
Expression is enriched in embryonic gonads.
Identification: Yeast two hybrid study using full length sina to screen a SL2 cDNA library.
Mutants suppress the nodDTW phenotype.
Source for identity of: lwr CG3018
'semushi' means 'hunchback' in Japanese.
