FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Ctet\tetX
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General Information
Symbol
Ctet\tetX
Species
C. tetani
Name
tetanus toxin
Annotation Symbol
Feature Type
FlyBase ID
FBgn0016753
Gene Model Status
Stock Availability
Gene Summary
Contribute a Gene Snapshot for this gene.
Also Known As

TNT, TeTxLC, tetanus toxin light chain, TeTx, light chain of tetanus toxin

Foreign Gene Data

Foreign sequence; species == Clostridium tetani; gene == 'tetX, tetanus toxin'; UniProtKB:P04958.

Summaries
Alleles, Insertions, Transgenic Constructs
Classical and Insertion Alleles ( 0 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 22 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Ctet\tetX
Transgenic constructs containing regulatory region of Ctet\tetX
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
Sterility
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
aCC neuron & neuromuscular junction, with Scer\GAL4eve.RRC
aCC neuron & synapse, with Scer\GAL4eve.RRC
aCC neuron & synapse, with Scer\GAL4sca-537.4
antennal sense organ & neuron, with Scer\GAL4GH86
chemosensory sensory organ & neuron, with Scer\GAL4GH86
giant fibers & synapse, with Scer\GAL4c17
larval maxillary sense organ & neuron, with Scer\GAL4GH86
monopolar laminar cell & axon, with Scer\GAL4MZ1369
pharyngeal sense organ & neuron, with Scer\GAL4GH86
photoreceptor cell R7 & axon, with Scer\GAL4GMR.PF
photoreceptor cell R7 & axon, with Scer\GAL4MZ1369
photoreceptor cell R8 & axon, with Scer\GAL4GMR.PF
photoreceptor cell R8 & axon, with Scer\GAL4MZ1369
RP2 neuron & synapse, with Scer\GAL4sca-537.4
synapse & aCC neuron, with Scer\GAL4eve.RRK
synapse & RP2 neuron, with Scer\GAL4eve.RRK
Orthologs
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
Drosophila melanogaster (Fruit fly) (0)
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    Interaction Browsers
    Summary of Genetic Interactions
    Interaction Browsers
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    External Data
    Linkouts
    DroID - A comprehensive database of gene and protein interactions.
    Class of Gene
    Stocks and Reagents
    Other Comments

    Ctet\TeTxLC expressed in transgenic flies cleaves n-syb and abolishes synaptic transmission at a defined neuromuscular junction.

    Relationship to Other Genes
    Source for database merge of
    Additional comments
    Nomenclature History
    Source for database identify of
    Nomenclature comments
    Etymology
    Synonyms and Secondary IDs (24)
    Reported As
    Secondary FlyBase IDs
      Datasets (0)
      Study focus (0)
      Experimental Role
      Project
      Project Type
      Title
      Study result (0)
      Result
      Result Type
      Title
      External Crossreferences and Linkouts ( 1 )
      Linkouts
      DroID - A comprehensive database of gene and protein interactions.
      References (427)